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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Phytochemicals in Cancer Chemoprevention and Treatment: 2nd Edition

edited by

Wojciech Trybus

Ewa Trybus

and

Aneta Wȩgierek-Ciuk

submission deadline 20 Jul 2026 | 4 articles | Viewed by 17860 | Submission Open

Keywords: phytochemicals; chemoprevention; cancer therapy; oxidative stress; apoptosis; autophagy; mitotic catastrophe; cell cycle; cytotoxicity; DNA damage; molecular pathways

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Product in Skin Inflammation and Barrier Function Damage

edited by

Hsiu-Mei Chiang

submission deadline 20 Jul 2026 | 4 articles | Viewed by 12017 | Submission Open

Keywords: skin inflammation; barrier function damage; natural compounds; antioxidant properties; antiaging

(This special issue belongs to the Section Molecular Medicine)

Modulation of Oxidative Stress: A Global Perspective for Climate Change Adaptation

edited by

Tihomir Kovač

and

Tihana Marček

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1330 | Submission Open

Keywords: oxidative stress; modulation; climate change; environmental factors; adaption

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Innovative Strategies in Overcoming Antimicrobial Resistance: From Phage Therapy to Combination

edited by Rajnikant Sharma

submission deadline 20 Jul 2026 | Viewed by 350 | Submission Open

Keywords: bacteriophages; phage therapy; antimicrobial resistance; phage engineering; phage-antibiotic combination; phage pharmacokinetics

(This special issue belongs to the Section Molecular Microbiology)

Oral Cancer: Prophylaxis, Etiopathogenesis and Treatment, 2nd Edition

edited by

Violeta Popovici

and

Emma Adriana Ozon

submission deadline 31 Jul 2026 | 5 articles | Viewed by 12620 | Submission Open

Keywords: oral carcinogenesis; biomarkers; cell signaling; natural products; phytochemicals; medicinal plants; essential oils; antimicrobial activity; cytotoxicity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Food-Derived Natural Products and Their Biological Activities—2nd Edition

edited by

Yanfang Li

submission deadline 31 Jul 2026 | 6 articles | Viewed by 10265 | Submission Open

Keywords: food compounds; natural products; biologically active compounds; oxidative stress; anticancer; functionality of foods

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Phytochemicals: Therapeutic Potential in Metabolic Disorders and Cancer

edited by

Mohamed Addi

submission deadline 31 Jul 2026 | 2 articles | Viewed by 6751 | Submission Open

Keywords: phytochemicals; molecular mechanisms; cancer therapeutics; metabolic disorders; natural compounds; signal transduction; epigenetic regulation; oxidative stress; anti-inflammatory agents; plant-based

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Biologically Active Compounds: Sources, Mechanisms of Action, and Applications

edited by Yulian Tumbarski and

Ivan Ivanov

submission deadline 31 Jul 2026 | 9 articles | Viewed by 4952 | Submission Open

Keywords: biologically active compounds; natural products; mechanisms of action; structure–activity relationships; bioavailability; antioxidant activity; antimicrobial activity; anticancer activity; omics approaches; biomedical and industrial applications

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Multi-Omics Integration for Precision Medicine: From Pathogenesis, Diagnosis to Treatment

edited by

Sanghun Lee

, Brian Kwan and Kangjin Kim

submission deadline 31 Jul 2026 | 5 articles | Viewed by 3698 | Submission Open

Keywords: multi-omics integration; precision medicine; systems biology; biomarker discovery; genomics and transcriptomics; proteomics and metabolomics; disease pathogenesis; personalized therapy; machine learning in biology; translational research

(This special issue belongs to the Section Molecular Medicine)

Molecular Dynamics Simulations in Structural Biology: From Proteins to Complex Biomolecular Systems

edited by

Ana E. Ledesma

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1303 | Submission Open

Keywords: protein; molecular docking; dynamic simulation; biomolecular systems; molecular interactions; structural modification; enzyme activity; biological function; antioxidant activity; infrared spectroscopy

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Impacts of DNA Methylation as Epigenetic Drivers of Disease Onset and Progression

edited by Adam G. Marsh

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1233 | Submission Open

Keywords: epigenetics; DNA methylation; disease onset; disease progression; molecular mechanisms; molecular biomarkers; gene silencing; gene expression

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Tumor Immunotherapy: Mechanisms and Translation

edited by Yujiao Liu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 767 | Submission Open

Keywords: tumor immunotherapy; PD-1; tumor antigens; drug delivery system; combination strategies

(This special issue belongs to the Section Molecular Medicine)

Technological Advances Around Next-Generation Sequencing Application, 2nd Edition

edited by

Gaurav Tripathi

submission deadline 31 Jul 2026 | 1 articles | Viewed by 746 | Submission Open

Keywords: next-generation sequencing; single-cell sequencing; long-read sequencing; metagenomics; epigenomics; cancer genomics; clinical applications; liquid biopsy; CRISPR-Cas9; precision medicine; personalized healthcare

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Mechanisms of Animal Metabolism: Pathophysiological Implications in Tumor Progression

edited by

Cristian Gabriel Torres Mendoza

submission deadline 31 Jul 2026 | Viewed by 260 | Submission Open

Keywords: animal cancer metabolism; animal tumor diseases; Warburg effect; drug-resistance; therapeutic targets

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Innovations in Postharvest Biology and Molecular Research in Fruits

edited by Emilio Attinà

submission deadline 31 Jul 2026 | Viewed by 242 | Submission Open

Keywords: microplastics; ecosystems; contamination; wear and tear of plastic products; degradation of macroplastics; accumulation in the food chain; detection in human organs and tissues; transport of toxic substances; contamination of rivers; natural sites

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular and Cellular Insights into Musculoskeletal Oncology: Primary Tumors, Metastases, and Translational Advances

edited by Catalin Cristoiu and Georgian Iacobescu

submission deadline 31 Jul 2026 | Viewed by 185 | Submission Open

Keywords: musculoskeletal oncology; spinal tumors; molecular pathways; tumor microenvironment; metastatic bone disease; translational oncology

(This special issue belongs to the Section Molecular Medicine)

Molecular Research into Eye Lens Proteins

edited by

Michel-Edwar Mickael

and Tenzin Tender

submission deadline 31 Jul 2026 | Viewed by 179 | Submission Open

Keywords: alpha-crystallin; eye lens proteins; molecular chaperone; cataracts; neurodegenerative diseases; therapeutic applications

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Treatment of Kidney Diseases

edited by Junyi Zhu

submission deadline 10 Aug 2026 | 4 articles | Viewed by 3294 | Submission Open

Keywords: nephrotic syndrome; kidney disease; kidney injury

(This special issue belongs to the Section Molecular Medicine)

Omics Analysis for Personalized Medicine

edited by

Golder N. Wilson

and

Tadeja Kuret

submission deadline 20 Aug 2026 | 6 articles | Viewed by 11636 | Submission Open

Keywords: genomics; epigenomics; transcriptomics; proteomics; metabolomics; multi-omics; high throughput; personalized medicine; immune-mediated inflammatory diseases

(This special issue belongs to the Section Molecular Medicine)

Exploring Molecular Pathways in Skin Health and Diseases

edited by

Sullim Lee

submission deadline 20 Aug 2026 | 6 articles | Viewed by 10959 | Submission Open

Keywords: skin health; skin aging; skin disease; molecular pathways; oxidative stress; immune response; inflammatory skin diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Bioinformatics and Molecular Research on Alzheimer’s Disease

edited by Aristidis G. Vrahatis

submission deadline 20 Aug 2026 | 2 articles | Viewed by 9805 | Submission Open

Keywords: Alzheimer’s disease; single-cell sequencing; molecular biomarkers; single-cell RNA-seq; single-cell ATAC-seq; spatial transcriptomics

(This special issue belongs to the Section Molecular Medicine)

Nanotechnology‑Enhanced Precision Therapeutics

edited by

Milutin Stepić

and

Iva A. Popović

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2110 | Submission Open

Keywords: photodynamic therapy; photosensitisers; targeting nanocarriers; multifunctional nanoplatforms; nanotheranostics; active targeting of cancer; molecular drug targeting; drug metabolism and toxicity; pharmacogenetic testing; cancer microenvironment remodelling

(This special issue belongs to the Section Molecular Medicine)

Phagocytosis in Neurological Disorders: Molecular Mechanisms and Therapeutic Targets

edited by

Dimitrios I. Tsiptsios

and Konstantinos Anagnostopoulos

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1705 | Submission Open

Keywords: phagocytosis; endothelial cells; microglial cells; stroke; dementia; inflammation

(This special issue belongs to the Section Molecular Medicine)

Molecular Approaches in Early Detection and Targeted Therapies for Pancreatic Cancer

edited by

Hassan Mubarak Ishqi

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1268 | Submission Open

Keywords: pancreatic cancer; early detection; molecular biomarkers; targeted therapy; genomics; tumor microenvironment; precision medicine; transcriptomics; proteomics; cancer diagnostics

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of the Neuro-Musculoskeletal System

edited by

Adriano Polican Ciena

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1260 | Submission Open

Keywords: morphology; molecular biology; microscopy; neuromuscular junction; myotendinous junction

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Biology on Environmental Microorganisms

edited by

Mariusz Cycoń

submission deadline 20 Aug 2026 | 1 articles | Viewed by 485 | Submission Open

Keywords: environmental microbiology; metagenomics; microbial interactions; phage–host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Advances in the Synthesis and Molecular Design of Bioactive Heterocycles as Anticancer and Antioxidant Agents

edited by

Anca Stana

submission deadline 20 Aug 2026 | Viewed by 394 | Submission Open

Keywords: symmetry; asymmetry; antioxidant; anticancer; synergy; oxidative stress; cytotoxicity; molecular design; synthesis

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular and Cellular Mechanisms of Vascular Function and Dysfunction: Roles of the Endothelium and G-Protein Coupled Receptors

edited by John J. McGuire

submission deadline 20 Aug 2026 | Viewed by 310 | Submission Open

Keywords: endothelium; endothelial cells; vascular smooth muscle; platelets; G-protein coupled receptor; signal transduction; metabolic dysfunction; diabetes; inflammation; angiogenesis

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Therapeutic Approaches in Fibrosis and Tissue Remodeling

edited by Pulin Che and

Huachun Cui

submission deadline 20 Aug 2026 | Viewed by 276 | Submission Open

Keywords: fibrosis; tissue remodeling; biomarkers; molecular pathways; translational medicine; therapeutic strategies

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Innovative Approaches in Bone and Cartilage Regeneration: From Stem Cells to Organoids

edited by

Maria Giovanna Rizzo

submission deadline 30 Aug 2026 | 3 articles | Viewed by 3016 | Submission Open

Keywords: bone and cartilage biology; physiology; molecular biology; nutraceuticals; regenerative medicine

(This special issue belongs to the Section Molecular Medicine)

Design, Synthesis and Pharmacological Evaluation of Novel Small Molecule Leads: From Anti-Infective to Anti-Inflammatory Therapies

edited by

Anca Stana

and

Ioana Ionuț

submission deadline 30 Aug 2026 | Viewed by 208 | Submission Open

Keywords: drug design; pharmacological evaluation; antimicrobial resistance; infectious and inflammatory diseases; target validation

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Radiation-Induced Cellular and Molecular Responses

edited by

Carlo Aprile

submission deadline 31 Aug 2026 | 6 articles | Viewed by 24238 | Submission Open

Keywords: radiation; radiobiology; space radiobiology; heavy ions carcinogenesis; LinearNonTreshold; radionuclide therapy; alpha emitters; beta emitters; radiobiology

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Innovative Therapeutic Approaches in Inflammatory Diseases, Pioneering Precision Medicine Solutions, 2nd Edition

edited by

Hector A. Cabrera-Fuentes

Klaus T. Preissner

and

Elisabeth Deindl

submission deadline 31 Aug 2026 | 13 articles | Viewed by 12362 | Submission Open

Keywords: inflammatory diseases; autoimmune disorders; cytokine signaling; oxidative stress; therapies

(This special issue belongs to the Section Molecular Medicine)

Pharmacological Activities and Mechanisms of Action of Natural Products, 2nd Edition

edited by

Shining Loo

Antony Kam

and Simon Ming-Yuen Lee

submission deadline 31 Aug 2026 | 11 articles | Viewed by 9697 | Submission Open

Keywords: natural products; pharmacological activity; molecular mechanisms; therapeutic targets; structure–activity relationships; protein–ligand interactions; cell signaling pathways; enzyme inhibition/activation; molecular targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Autophagy and the Ubiquitin–Proteasome System: Regulators of Protein Homeostasis, Cell Death, and Disease Pathogenesis

edited by

Lei Dong

submission deadline 31 Aug 2026 | 4 articles | Viewed by 8189 | Submission Open

Keywords: autophagy; ubiquitin–proteasome system; protein homeostasis; autophagosome; cell death regulation; cancer; Alzheimer's disease

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers

edited by

Stergios Boussios

submission deadline 31 Aug 2026 | 3 articles | Viewed by 6188 | Submission Open

Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Plant Adaptation and Stress Tolerance Under Changing Environmental Conditions

edited by

Naveed Ahmad

submission deadline 31 Aug 2026 | 5 articles | Viewed by 5081 | Submission Open

Keywords: elevated CO2; drought–heat–salinity; carbon–nitrogen balance; TOR/SnRK1; hormone crosstalk; redox signaling; microbiome; single-cell/spatial omics; phenomics; genome editing; predictive breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular and Pharmacological Insights into Bioactive Compounds: Pathways to Therapeutics

edited by

Mosharraf Sarker

and

Talat Nasim

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4961 | Submission Open

Keywords: bioactive compounds; natural products; drug discovery; pharmacology; therapeutic pathways; molecular mechanisms; signal transduction; medicinal chemistry; target identification

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights and Therapeutic Advances in Hematological Disorders, 2nd Edition

edited by

Eleni Gavriilaki

submission deadline 31 Aug 2026 | 4 articles | Viewed by 4402 | Submission Open

Keywords: acute leukemia; myeloproliferative neoplasms; lymphoma; multiple myeloma; hemoglobinopathies; hemophilia

(This special issue belongs to the Section Molecular Medicine)

Unraveling the Role of Epigenetics and Molecular Genetics in Disease Progression via the Gut–Brain Axis

edited by Yong-Chan Kim

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4158 | Submission Open

Keywords: prion diseases; Parkinson’s disease; Alzheimer’s disease; neurodegenerative disease; inflammatory bowel diseases; ulcerative colitis; Crohn’s disease; brain–gut axis; bioinformatics; polymorphism

(This special issue belongs to the Section Molecular Medicine)

The Modulatory Effects of Plants with Therapeutic Potential in Neuropsychiatric Disorder

edited by

Alin Ciobica

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4100 | Submission Open

Keywords: plant biodiversity; antioxidant effects; therapeutic potential; neuropsychiatric disorders; oxidative stress markers; inflammatory markers

(This special issue belongs to the Section Molecular Pharmacology)

Hormonal Regulation in Germ Cell Development

edited by

Kwan Sik Min

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3358 | Submission Open

Keywords: spermatogenesis; steroidogenesis; sex hormones; sex hormone receptors; gonadotropin; germ cell differentiation; androgen; luteinizing hormone; follicle-stimulating hormone; glycoprotein hormone receptors

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Markers of Tumor Response and Toxicity of Antitumor Therapy

edited by

Liudmila V. Spirina

and

Natalya V. Yunusova

submission deadline 31 Aug 2026 | 4 articles | Viewed by 2808 | Submission Open

Keywords: anti-cancer therapy; side effect; tumor response; toxicity; molecular markers

(This special issue belongs to the Section Molecular Medicine)

Molecular Research in Osteoarthritis and Osteoarticular Diseases, 2nd Edition

edited by

Ye Liu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2745 | Submission Open

Keywords: osteoarthritis; cartilage regeneration; bioinformatics; biomarkers; inflammation; cartilage; metabolic imbalance

(This special issue belongs to the Section Molecular Medicine)

Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition

edited by

Chingyuan Wu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2436 | Submission Open

Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19

(This special issue belongs to the Section Molecular Medicine)

Redox Imbalance and Inflammatory Signaling in Disease Mechanisms and Therapeutic Strategies

edited by

Dušan T. Sokolović

and

Nikola Stojanović

submission deadline 31 Aug 2026 | 1 articles | Viewed by 518 | Submission Open

Keywords: redox signaling; inflammatory; oxinflammation

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Mycobacterial Infections: Redox Modulation, Cytokine Reprogramming, and Host-Directed Therapy

edited by

Vishwanath Venketaraman

submission deadline 31 Aug 2026 | Viewed by 203 | Submission Open

Keywords: TB; NTM; redox imbalance; cytokine reprogramming; host-directed therapy

(This special issue belongs to the Section Molecular Microbiology)

Molecular Characteristics and Diagnostic Biomarkers in Tumors

edited by Anjali Seth and Israh Akhtar

submission deadline 31 Aug 2026 | Viewed by 200 | Submission Open

Keywords: tumor molecular profiling; diagnostic biomarkers; precision oncology; cancer genomics

(This special issue belongs to the Section Molecular Medicine)

Molecular and Cellular Mechanisms of Neurodegenerative Disease

edited by

Chryssa Bekiari

and

Anastasia Tsingotjidou

submission deadline 31 Aug 2026 | Viewed by 196 | Submission Open

Keywords: Alzheimer’s disease; neurodegeneration; functional neuroanatomy; transgenic animal models; brain imaging

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Emerging Trends for Genome-Wide Association Studies in Complex Disease Genetics

edited by

Xiaowei Wu

submission deadline 20 Sep 2026 | 4 articles | Viewed by 4657 | Submission Open

Keywords: GWAS; polygenic risk scores; rare variants; structural variants; multi-omics; Mendelian randomization; population structure and relatedness; machine learning; Bayesian models; stochastic models

(This special issue belongs to the Section Bioinformatics and Systems Biology)

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