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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of the Neuro-Musculoskeletal System

edited by

Adriano Polican Ciena

submission deadline 20 Feb 2026 | Viewed by 200 | Submission Open

Keywords: morphology; molecular biology; microscopy; neuromuscular junction; myotendinous junction

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Bioinformatics Research in Bacterial Genomics, Metagenomics and Metatranscriptomics: 2nd Edition

edited by

Vesselin Baev

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3472 | Submission Open

Keywords: bacterial genomics and functional analysis; genome-wide comparative genomics; bioinformatics methods and tools; metagenomics; metatranscriptomics

(This special issue belongs to the Section Molecular Microbiology)

Hyperlipidemia and Molecular Mechanism in Human and Animals

edited by

Kyuhyung Choi

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3383 | Submission Open

Keywords: hyperlipidemia; diabetes mellitus; Cushing’ s disease; pancreatitis; gall bladder mucoceles

(This special issue belongs to the Section Molecular Medicine)

Latest Review Papers in Molecular Plant Science 2026

edited by

Zhaohui Chu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1973 | Submission Open

Keywords: multi-omics; plant bioreactor; plant genomics; plant-pathogens interaction; crop domestication; crop yield traits

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Natural Product-Induced Immune Modulation: From Signaling Pathways to Therapeutic Targets

edited by Suyun Lyu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: natural products; immunomodulation; immune responses; molecular mechanisms; immune cell activation; inflammation pathways; autoimmune diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Innovations in Antimicrobial Resistance

edited by

Rúben Fernandes

submission deadline 28 Feb 2026 | Viewed by 650 | Submission Open

Keywords: antimicrobial resistance (AMR); molecular mechanisms; genomics; personalized medicine; resistance mechanisms; translational research

(This special issue belongs to the Section Molecular Microbiology)

Epigenetics and Chromatin Remodeling in Cancer

edited by

Gianluca Tedaldi

submission deadline 28 Feb 2026 | Viewed by 267 | Submission Open

Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy

(This special issue belongs to the Section Molecular Medicine)

Current Advances in Oxytocin Research, 2nd Edition

edited by

Claudia Camerino

submission deadline 28 Feb 2026 | Viewed by 217 | Submission Open

Keywords: oxytocin; thermoregulation; skeletal muscle; obesity; Prader– Willi syndrome

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Stem Cell-Derived Cells and Bioengineering: Molecular Bases in Regeneration and Disease Research

edited by Aylin Acun

submission deadline 28 Feb 2026 | Viewed by 171 | Submission Open

Keywords: stem cells; regenerative medicine; bioengineering; disease modeling; organoids; tissue engineering; decellularization; bioprinting

(This special issue belongs to the Section Molecular Medicine)

Molecular Biology and Functional Roles of Tumor Suppressor Genes in Cancer

edited by

Yun Zhang

submission deadline 28 Feb 2026 | Viewed by 145 | Submission Open

Keywords: tumor suppressor genes; cancer biology; TP53; RB1; PTEN; genomic instability; tumor microenvironment; cancer therapy; epigenetic regulation; cell signaling

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

The Role of Microglia in Neuroinflammation and Neurodegenerative Diseases

edited by

Shunqi Wang

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: microglia; neuroinflammation; neurodegeneration; synaptic pruning; microglial activation states; innate immune signaling; TLR signaling; TREM2; CX3CR1; NF-κ B; glia– neuron interactions; neuroimmune crosstalk; therapeutic targeting of microglia

(This special issue belongs to the Section Molecular Medicine)

Innovative Models for SARS-CoV-2 Pathogenesis

edited by

Virginia Lotti

submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open

Keywords: SARS-CoV-2; coronavirus; virus infection; pathogenesis; innovative models

(This special issue belongs to the Section Molecular Medicine)

Multiomics of Cancer Research in Human and Animals

edited by

Kyuhyung Choi

submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open

Keywords: multiomics; cancer; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Drug Design and Drug Discovery

edited by

Arjun Singh

submission deadline 5 Mar 2026 | 1 articles | Viewed by 1573 | Submission Open

Keywords: drug discovery; drug design; artificial intelligence; structure-based drug design; omics; biologics; precision medicine; drug repurposing

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms Driving Cancer Progression and Metastasis

edited by

Karolina Bajdak-Rusinek

submission deadline 15 Mar 2026 | 1 articles | Viewed by 379 | Submission Open

Keywords: cancer progression; metastasis; epithelial– mesenchymal transition (EMT); tumor plasticity; tumor microenvironment; signaling pathways; therapy resistance

(This special issue belongs to the Section Molecular Medicine)

Mechanisms and Pathophysiology of Obesity

edited by Padmamalini Baskaran

submission deadline 20 Mar 2026 | 4 articles | Viewed by 15535 | Submission Open

Keywords: understanding genetic factors for obesity at the molecular level; understanding environmental factors for obesity at the molecular level; contribution of insulin resistance to obesity and ways to combat; circadian misalignment– molecular level understanding of its contribution to obesity and ways to mitigate it; effective and individualized obesity treatment strategies for stress; molecular understanding of the influence of parental obesity on childhood overweight; molecular mechanisms of maternal smoking on childhood obesity; therapeutic interventions for obesity through recombinant hormones; role of gut hormones in the treatment of obesity; development of new digital tools for weight management interventions

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Biology and Therapeutics: From Natural Products to Pharmaceutical Agents

edited by

Budimir S. Ilić

submission deadline 30 Mar 2026 | Viewed by 131 | Submission Open

Keywords: natural products; molecular biology; medicinal chemistry; drug discovery; therapeutic agents; molecular dynamics; QSAR modeling; ADMET profiling; antimicrobial resistance; translational pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity

edited by Bogdana Virgolici

submission deadline 31 Mar 2026 | 9 articles | Viewed by 33846 | Submission Open

Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Regulation in Allergy and Immune Diseases, Immunodeficiencies, 2nd Edition

edited by

Kinga Lis

submission deadline 31 Mar 2026 | 6 articles | Viewed by 27048 | Submission Open

Keywords: allergy and hypersensitivity mechanisms; cross-reactivity in allergy; component resolved diagnostic (CRD); immunodeficiencies; experimental research methods in allergology; biochemical properties of allergens

(This special issue belongs to the Section Molecular Medicine)

Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition

edited by

Hidayat Hussain

submission deadline 31 Mar 2026 | 7 articles | Viewed by 17082 | Submission Open

Keywords: natural products; natural product derivatives; antidiabetic agents; α -glucosidase inhibitors; amylase inhibitors; PTP1B inhibitors; DPP-4 inhibitors; molecular level; kinetic studies; in vitro studies; in vivo studies; computational methods; mode of action

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Research in Bioactivity of Natural Products, 3rd Edition

edited by

Magdalena Bartnik

and

Wirginia Kukula-Koch

submission deadline 31 Mar 2026 | 2 articles | Viewed by 6859 | Submission Open

Keywords: molecular research; molecular properties; metabolic pathway; phytochemicals; natural products; apoptosis; bioactivity assessment; chemical composition; therapeutic targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Targeted Therapeutic Approaches in Cancer: Combining Natural Compounds and Conventional Drugs

edited by

Alok Bhushan

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5281 | Submission Open

Keywords: natural compounds; cancer; repurposing; combination; polychemotherapy; pharmaceuticals; nutraceuticals; molecular targets; metabolomics; immunotherapy

(This special issue belongs to the Section Molecular Medicine)

The Significance of Transcription Factors, miRNAs, and lncRNAs in Anticancer Drug Development, 2nd Edition

edited by

Ru Chih C. Huang

and

Kotohiko Kimura

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5205 | Submission Open

Keywords: transcription factors; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); anticancer drugs; cancer; coactivators

(This special issue belongs to the Section Molecular Medicine)

Therapeutic Effects of Natural Bioactive Compounds in the Management of Human Diseases: 2nd Edition

edited by

Rossana Morabito

and

Sara Spinelli

submission deadline 31 Mar 2026 | 4 articles | Viewed by 4589 | Submission Open

Keywords: natural bioactive compound; human health; chronic diseases; molecular target; oxidative stress; inflammation; cancer; diabetes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Effects of Nanoparticles on Living Organisms, 3rd Edition

edited by

Yoshitaka Miyamoto

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4061 | Submission Open

Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological; inflammatory; and allergic diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Featured Papers in Bioinformatics and Systems Biology

edited by

Howard H. Yang

submission deadline 31 Mar 2026 | 4 articles | Viewed by 2642 | Submission Open

Keywords: bioinformatics; omics; genomics and transcriptomics sequence analyses; dynamic modeling

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Mechanisms and Therapeutic Advances in Hypertension Management and Vascular Health

edited by

Federica Fogacci

Arrigo Francesco Giuseppe Cicero

and

Claudio Borghi

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1899 | Submission Open

Keywords: hypertension; vascular aging; endothelial dysfunction; gestational hypertension; metabolic disorders; therapeutic strategies in hypertension management

(This special issue belongs to the Section Molecular Medicine)

Molecular Roles of Neutrophil Extracellular Traps in Immune Responses and Disease

edited by Sofía S. Jerez

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1850 | Submission Open

Keywords: neutrophils; NET; inflammation; chronic diseases; cell death

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Basis of Autoimmune Diseases

edited by

Ranjeet Singh Mahla

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1558 | Submission Open

Keywords: autoimmune diseases; immune regulation; molecular mechanisms; genetic predisposition; epigenetics; cytokines; biomarkers; immune checkpoints; targeted therapies; genomics; transcriptomics; proteomics; systems biology; inflammation; immune tolerance

(This special issue belongs to the Section Molecular Medicine)

Precision Molecular Oncology: From Tumor Biomarker Discovery to Next-Generation Drug Delivery

edited by

Farhadul Islam

submission deadline 31 Mar 2026 | Viewed by 1306 | Submission Open

Keywords: precision oncology; molecular pathology; personalized treatment; tumor marker; biomarkers; multi-omics; drug discovery; nanocarriers; drug delivery; clinical management

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Gut Biology: Stem Cells, Organoids, and Microbiota–Immune Interactions

edited by

Shaoyi Zhang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1095 | Submission Open

Keywords: intestinal stem cells; intestinal organoids; gut– microbiota interaction; mucosal immunology; molecular mechanisms; gut epithelial regeneration; microbiota– immune crosstalk; organoid disease models; intestinal homeostasis; molecular gut biology

(This special issue belongs to the Section Molecular Microbiology)

Neural Networks in Molecular and Cellular Neurobiology

edited by

Paschalis Theotokis

submission deadline 31 Mar 2026 | 1 articles | Viewed by 769 | Submission Open

Keywords: neural networks; neuroplasticity; intracellular signaling; computational neuroscience; artificial intelligence; neuromorphic computing

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Emerging Trends for Genome-Wide Association Studies in Complex Disease Genetics

edited by

Xiaowei Wu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 483 | Submission Open

Keywords: GWAS; polygenic risk scores; rare variants; structural variants; multi-omics; Mendelian randomization; population structure and relatedness; machine learning; Bayesian models; stochastic models

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Emerging Trends in Bioinformatics and Computational Biology

edited by Haijun Gong

submission deadline 31 Mar 2026 | Viewed by 450 | Submission Open

Keywords: bioinformatics; computational biology; genomics; proteomics; metabolomics; multi-omics; machine learning; algorithms; big data; molecular diagnostics; personalized medicine; data visualization

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Molecular Research on Free Radicals and Oxidative Stress—2nd Edition

edited by

Mosharraf Sarker

submission deadline 31 Mar 2026 | 1 articles | Viewed by 427 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); gene regulation; antioxidants; mitochondrial dysfunction; insulin resistance; inflammation; autophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Oxidative Stress and Inflammation

edited by Md. Sohanur Rahman

submission deadline 31 Mar 2026 | Viewed by 346 | Submission Open

Keywords: oxidative stress; inflammation; redox signaling; mitochondrial dysfunction; antioxidant therapy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Antimicrobial or Antibiofilm Activity of Biodegradable Substances

edited by

Miyako Yoshida

submission deadline 31 Mar 2026 | 1 articles | Viewed by 261 | Submission Open

Keywords: antibacterial; antibiofilm; antimicrobial; biodegradable; drug-resistance

(This special issue belongs to the Section Molecular Microbiology)

The Molecular Pathways Involved in Atopic Dermatitis: Implications for Targeted Therapy

edited by

Ciro Martins Gomes

submission deadline 31 Mar 2026 | Viewed by 258 | Submission Open

Keywords: atopic dermatitis; biological products; cytokines; Th2 cells; eczema; Janus kinase inhibitors

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Scoliosis and Spinal Disorders: Molecular Biomarkers and Therapeutic Strategies

edited by

Angelos Kaspiris

submission deadline 31 Mar 2026 | Viewed by 217 | Submission Open

Keywords: intracellular interactions during the progression of spinal disorders; molecular signaling in scoliosis; growth factor expression in spinal disorders and deformities; biomarkers; molecular-driven treatment

(This special issue belongs to the Section Molecular Medicine)

Molecular Studies of Bioactive Compounds and Their Therapeutic Potential

edited by Sanja Radman and

Ivana Carev

submission deadline 31 Mar 2026 | Viewed by 165 | Submission Open

Keywords: bioactive compounds; molecular mechanisms; structural elucidation; molecular targets; omics approaches

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Genetics and Genomics Research of Autism Spectrum Disorders

edited by

Golder N. Wilson

submission deadline 31 Mar 2026 | Viewed by 139 | Submission Open

Keywords: autism; neurodevelopmental disorders; genomics; copy number variants; next-generation sequencing

(This special issue belongs to the Section Molecular Medicine)

Molecular Research on Growth Hormones and Related Hormones and Peptides

edited by Hugo Alberto Barrera-Saldaña

submission deadline 31 Mar 2026 | Viewed by 115 | Submission Open

Keywords: growth hormones; insulin-like growth factor; prolactin; vasoinhibin; antiangiogenic

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advancements in Mass Spectrometry-Based Lipidomics for Molecular Biology Research

edited by Hua Tian

submission deadline 31 Mar 2026 | Viewed by 109 | Submission Open

Keywords: lipidomics; high resolution; spatial omics; single cell

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Complex Molecular Mechanism of Monogenic Diseases: 3rd Edition

edited by

Grzegorz Wegrzyn

submission deadline 20 Apr 2026 | 7 articles | Viewed by 21714 | Submission Open

Keywords: cystic fibrosis; sickle cell disease; duchenne muscular dystrophy; inherited monogenic disease; molecular mechanisms

(This special issue belongs to the Section Molecular Medicine)

Natural Product Drug Activity and Biomedicine Application

edited by

Anna Makuch-Kocka

submission deadline 30 Apr 2026 | 10 articles | Viewed by 22584 | Submission Open

Keywords: natural products; signaling pathways; epignetic regulation; cell communication; molecular biology

(This special issue belongs to the Section Molecular Pharmacology)

Intestinal Inflammation: From Molecular Mechanisms to Therapeutic Strategies

edited by

Raffaele Pellegrino

and

Antonietta Gerarda Gravina

submission deadline 30 Apr 2026 | 4 articles | Viewed by 12289 | Submission Open

Keywords: inflammatory bowel disease; celiac disease; Crohn's Disease; ulcerative colitis; colitis; hemorrhoidal disease

(This special issue belongs to the Section Molecular Medicine)

The Role of Bioactives in Inflammation, 2nd Edition

edited by

Chan-Yen Kuo

submission deadline 30 Apr 2026 | 7 articles | Viewed by 8359 | Submission Open

Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanism and Advances in Gynecological Pathology: From Bench to Bedside

edited by

Ahsanullah Unar

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5096 | Submission Open

Keywords: gynecological cancers; molecular pathology; biomarkers; genetic alterations; epigenetics; tumor microenvironment; personalized medicine; targeted therapy; endometriosis; ovarian cancer

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Pathogenesis, Diagnosis and Treatment of Skin and Sexually Transmitted Diseases

edited by

Maria Eleni Manthou

, Efstratios Vakirlis and

Iasonas Dermitzakis

submission deadline 30 Apr 2026 | 4 articles | Viewed by 5009 | Submission Open

Keywords: pathogenesis; diagnosis; treatment; dermatology; STDs; molecular; immunology; inflammation; genomics; precision

(This special issue belongs to the Section Molecular Medicine)

Mechanistic Insights into the Antioxidant Activity of Bioorganic Molecules: A Chemical Perspective

edited by

Tatjana S. Radosavljević

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4998 | Submission Open

Keywords: antioxidant mechanisms; bioorganic molecules; redox -active compounds; molecular reactivity; oxidative stress modulation

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

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