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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanism and Advances in Gynecological Pathology: From Bench to Bedside
edited by
submission deadline 20 Jul 2025 | Viewed by 295 | Submission Open
Keywords: gynecological cancers; molecular pathology; biomarkers; genetic alterations; epigenetics; tumor microenvironment; personalized medicine; targeted therapy; endometriosis; ovarian cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Pharmacological Activities and Mechanisms of Action of Natural Products
edited by , and Lee Simon Ming-Yuen
submission deadline 31 Jul 2025 | 13 articles | Viewed by 18844 | Submission Open
Keywords: natural products; pharmacological activity; molecular mechanisms; therapeutic targets; structure– activity relationships; protein– ligand interactions; cell signaling pathways; enzyme inhibition/activation; molecular targets
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Biology in Drug Design and Precision Therapy submission deadline 31 Jul 2025 | 10 articles | Viewed by 13372 | Submission Open
Keywords: molecular biology; drug design; molecular targets; disease mechanisms; structural biology; computational chemistry; pharmacology; precision medicine; molecular pathways; personalized therapy; drug research
(This special issue belongs to the Section Molecular Medicine)
Infectious Diseases and Molecular Epidemiology: A Focus on Pathogenic Microorganisms
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 13149 | Submission Open
Keywords: infectious disease; malaria; meningitis; pathogene
(This special issue belongs to the Section Molecular Microbiology)
Cellular and Molecular Biology Insights into Neurodegenerative Diseases: From Pathogenesis to Therapeutic Targets submission deadline 31 Jul 2025 | 5 articles | Viewed by 9415 | Submission Open
Keywords: neurodegenerative disease; oxidative stress; ER stress; mitochondrial stress; corrector; misfolding protein; preoteostasis; neuroblastoma
(This special issue belongs to the Section Molecular Medicine)
Exosomes in Tissue Regeneration and Disease Therapy
edited by
submission deadline 31 Jul 2025 | 5 articles | Viewed by 8195 | Submission Open
Keywords: exosomes; tiny vesicles; cell-specific proteins; exosome-mediated; human diseases
(This special issue belongs to the Section Molecular Medicine)
Molecular Breeding and Genetics Research in Plants, 2nd Edition
edited by
submission deadline 31 Jul 2025 | 8 articles | Viewed by 8025 | Submission Open
Keywords: genetic basis; genomic selection/prediction; molecular breeding; biotic and abiotic stresses; qPCR
(This special issue belongs to the Section Molecular Plant Sciences)
Neuropharmacology and Brain Physiology: From Molecular Mechanisms to Medicines Application
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 6511 | Submission Open
Keywords: neuropsychopharmacology; neurotransmitters; neuropeptides; receptor proteins; agonist; competitive antagonist; non-competitive antagonist
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanism of Plant Growth, Development and Secondary Metabolism
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 5885 | Submission Open
Keywords: secondary metabolites; plant defense; signaling and adaptation mechanisms; plant development; genetic and epigenetic regulation; plant physiology
(This special issue belongs to the Section Molecular Plant Sciences)
Radiation-Induced Cellular and Molecular Responses
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 5730 | Submission Open
Keywords: radiation; radiobiology; space radiobiology; heavy ions carcinogenesis; LinearNonTreshold; radionuclide therapy; alpha emitters; beta emitters; radiobiology
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity
edited by Bogdana Virgolici
submission deadline 31 Jul 2025 | 4 articles | Viewed by 4451 | Submission Open
Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms in Plant Stress Tolerance
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 4435 | Submission Open
Keywords: plant stress tolerance; molecular mechanisms; stress-responsive gene; signal transduction pathways; epigenetic modifications; phytohormones (ethylene; ABA; SA; JA); reactive oxygen species (ROS); plant– microbe interactions; microbial plant bio-stimulants; omics approaches (genomics; transcriptomics; proteomics; and metabolomics)
(This special issue belongs to the Section Molecular Plant Sciences)
Epithelial Cancers: Molecular Mechanisms, Diagnostic Innovations, and Therapeutic Advances
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2810 | Submission Open
Keywords: epithelial cancers; molecular mechanisms; genetic alterations; epigenetics; tumor microenvironment; epithelial-mesenchymal transition; biomarkers; liquid biopsy; imaging technologies; targeted therapies; immunotherapies; personalized medicine; treatment resistance; cancer recurrence; translational research
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2331 | Submission Open
Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 2nd Edition
edited by Haibo Dong and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 1995 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions
(This special issue belongs to the Section Molecular Medicine)
Angiogenesis in Diseases: Molecular Mechanism and Regulation submission deadline 31 Jul 2025 | 1 articles | Viewed by 1551 | Submission Open
Keywords: blood vessels; angiogenic factors; trophic factors; angiogenesis biomarkers; cancers; heart diseases
(This special issue belongs to the Section Molecular Medicine)
Exploring Molecular Pathways in Skin Health and Diseases
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1226 | Submission Open
Keywords: skin health; skin aging; skin disease; molecular pathways; oxidative stress; immune response; inflammatory skin diseases
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular and Pharmacological Insights into Bioactive Compounds: Pathways to Therapeutics submission deadline 31 Jul 2025 | 1 articles | Viewed by 662 | Submission Open
Keywords: bioactive compounds; natural products; drug discovery; pharmacology; therapeutic pathways; molecular mechanisms; signal transduction; medicinal chemistry; target identification
(This special issue belongs to the Section Molecular Pharmacology)
Tumor Microenvironment: Crosstalk Between Epigenetics, Metabolism and Immunity
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 652 | Submission Open
Keywords: tumor microenvironment; epigenetic modifications; metabolic reprogramming; immune escape; tumor metastasis; therapeutic resistance
(This special issue belongs to the Section Molecular Medicine)
Autophagy and the Ubiquitin–Proteasome System: Regulators of Protein Homeostasis, Cell Death, and Disease Pathogenesis
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 445 | Submission Open
Keywords: autophagy; ubiquitin– proteasome system; protein homeostasis; autophagosome; cell death regulation; cancer; Alzheimer's disease
(This special issue belongs to the Section Molecular Medicine)
The Molecular Basis of Genetic and Epigenetic Changes in Cancer
edited by Su Yon Jung
submission deadline 31 Jul 2025 | Viewed by 324 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; epigenome; DNA methylation; biomarkers; gene expression; proteomics; cancer(s); prediction; prevention; screening; prognosis; treatment; infection; COVID-19; interaction with the environment; occupational hazard
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 242 | Submission Open
Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19
(This special issue belongs to the Section Molecular Medicine)
Omics Technologies and Genomic Studies Unraveling Alzheimer’s Disease Heterogeneity
edited by
submission deadline 31 Jul 2025 | Viewed by 114 | Submission Open
Keywords: Alzheimer; multi-omics approaches; heterogeneity; genetic loci and biomarkers; neurodegenerative disease research
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Epigenetics and Chromatin Remodeling in Cancer
edited by
submission deadline 31 Jul 2025 | Viewed by 90 | Submission Open
Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy
(This special issue belongs to the Section Molecular Medicine)
Phagocytosis in Neurological Disorders: Molecular Mechanisms and Therapeutic Targets
edited by and Konstantinos Anagnostopoulos
submission deadline 31 Jul 2025 | Viewed by 80 | Submission Open
Keywords: phagocytosis; endothelial cells; microglial cells; stroke; dementia; inflammation
(This special issue belongs to the Section Molecular Medicine)
Exploring Symmetry and Asymmetry in Molecular Design for Anticancer and Antioxidant Therapies
edited by
submission deadline 20 Aug 2025 | Viewed by 116 | Submission Open
Keywords: symmetry; asymmetry; antioxidant; anticancer; synergy; oxidative stress; cytotoxicity; molecular design; synthesis
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Research in Chronic Dermatoses, 2nd Edition submission deadline 31 Aug 2025 | 2 articles | Viewed by 12846 | Submission Open
Keywords: dermatopathology; dermatosurgery; skin biology; molecular biology; genetics; JAK inhibitors; antibodies
(This special issue belongs to the Section Molecular Medicine)
The Role of Neuroinflammation in Neurodegenerative Diseases
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 9607 | Submission Open
Keywords: molecular neuropathology; neuroinflammation; multiple sclerosis; neurodegenerative diseases; dementias
(This special issue belongs to the Section Molecular Medicine)
Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 8618 | Submission Open
Keywords: natural products; natural product derivatives; antidiabetic agents; α -glucosidase inhibitors; amylase inhibitors; PTP1B inhibitors; DPP-4 inhibitors; molecular level; kinetic studies; in vitro studies; in vivo studies; computational methods; mode of action
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Metabolic Interactions Between the Gut Microbiome and Organism
edited by Sree V. Chintapalli
submission deadline 31 Aug 2025 | 3 articles | Viewed by 8408 | Submission Open
Keywords: microbiota dysbiosis; metabolism; inflammation; gut– brain axis; metabolic interactions
(This special issue belongs to the Section Molecular Microbiology)
Recombinant Proteins for Molecular Biology Research: Technologies and Applications submission deadline 31 Aug 2025 | 5 articles | Viewed by 7544 | Submission Open
Keywords: recombinant proteins; vaccine; intra-cellular signaling factors; membrane proteins; drug targets
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Network Pharmacology, Multi-targets and Receptor–Receptor Interactions in the CNS submission deadline 31 Aug 2025 | 3 articles | Viewed by 7151 | Submission Open
Keywords: network pharmacology; multi-targets; receptor– receptor interactions; target proteins; drug therapy in CNS; receptors
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Insights and Therapeutic Advances in Hematological Disorders
edited by
submission deadline 31 Aug 2025 | 6 articles | Viewed by 7129 | Submission Open
Keywords: acute leukemia; myeloproliferative neoplasms; lymphoma; multiple myeloma; hemoglobinopathies; hemophilia
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms in Demyelinating Disorders and Remyelination Strategies of the CNS submission deadline 31 Aug 2025 | 4 articles | Viewed by 6372 | Submission Open
Keywords: demyelination; molecular mechanisms; oligodendrocyte precursor cells; myelinogenesis; dysmyelination; lipid metabolism; microglia and macrophages; experimental autoimmune encephalomyelitis; biomarkers; remyelination
(This special issue belongs to the Section Molecular Medicine)
Linking Genomic Changes with Cancer in the NGS Era, 2nd Edition
edited by Javier Azúa-Romeo and
submission deadline 31 Aug 2025 | 5 articles | Viewed by 5678 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; driver gene; functional validation; gene editing; cancer
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Advanced Molecular Research on Hypertensive Disorders of Pregnancy (HDPs)
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 5325 | Submission Open
Keywords: DNA; RNA; protein; microbiome; hypertensive disorders of pregnancy; preeclampsia; epidemiology; meta-analysis
(This special issue belongs to the Section Molecular Medicine)
Editorial Board Members' Collection Series: Natural Product Pharmacology submission deadline 31 Aug 2025 | 1 articles | Viewed by 3886 | Submission Open
Keywords: natural compounds; bioactive molecules; molecular mechanisms; therapeutic targets; drug discovery; pharmacokinetics; pharmacodynamics; cellular signaling pathways
(This special issue belongs to the Section Molecular Pharmacology)
Innovative Strategies and Applications for Drug Discovery
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3436 | Submission Open
Keywords: drug discovery; computational strategies; molecular docking; pharmacophore modeling; molecular dynamics simulations
(This special issue belongs to the Section Molecular Medicine)
Genomic Analysis of Common Disease, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 3285 | Submission Open
Keywords: genomic analysis; microarray analysis; whole exome sequencing; pathogenic mutations; copy number variants; DNA sequence variation; intellectual disability; autism; connective tissue dysplasia
(This special issue belongs to the Section Molecular Medicine)
Cancer Biomarkers: Discovery and Applications
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3166 | Submission Open
Keywords: cancer biomarkers; precision medicine; prevention; prognosis; diagnosis
(This special issue belongs to the Section Molecular Medicine)
Mental Disorder: Focus on Pathogenesis to Treatment
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 2642 | Submission Open
Keywords: mental disorders; neurobiological; oxidative stress; neuroinflammation; gene variants
(This special issue belongs to the Section Molecular Medicine)
Unraveling the Molecular Marvels of Heart Repair and Regeneration
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1793 | Submission Open
Keywords: cardiac repair; angiogenesis; heart failure; ischemia; reperfusion; reactive oxygen; cell therapy; exosome therapy; gene therapy; apoptosis; ischemic preconditioning; gene editing
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Food-Derived Natural Products and Their Biological Activities—2nd Edition
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1792 | Submission Open
Keywords: food compounds; natural products; biologically active compounds; oxidative stress; anticancer; functionality of foods
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Significance of Transcription Factors, miRNAs, and lncRNAs in Anticancer Drug Development, 2nd Edition submission deadline 31 Aug 2025 | 3 articles | Viewed by 1766 | Submission Open
Keywords: transcription factors; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); anticancer drugs; cancer; coactivators
(This special issue belongs to the Section Molecular Medicine)
Hormonal Regulation in Germ Cell Development
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1503 | Submission Open
Keywords: spermatogenesis; steroidogenesis; sex hormones; sex hormone receptors; gonadotropin; germ cell differentiation; androgen; luteinizing hormone; follicle-stimulating hormone; glycoprotein hormone receptors
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Modulatory Effects of Plants with Therapeutic Potential in Neuropsychiatric Disorder
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1314 | Submission Open
Keywords: plant biodiversity; antioxidant effects; therapeutic potential; neuropsychiatric disorders; oxidative stress markers; inflammatory markers
(This special issue belongs to the Section Molecular Pharmacology)
Insights from Genetics, Epigenetics, and Microbiome Research in Obesity: Integrative Approaches to Understand Metabolic Disorders
edited by Shengping Yang
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1154 | Submission Open
Keywords: obesity; epigenetics; microbiom; genetics; bioinformatics
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Early Molecular Diagnosis and Comprehensive Treatment of Tumors
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1081 | Submission Open
Keywords: next-generation sequencing (NGS); novel biomarkers; precision medicine; targeted therapy; immunotherapy; integrative treatment; personalized cancer treatment
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Bioinformatics Research in Bacterial Genomics, Metagenomics and Metatranscriptomics: 2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 743 | Submission Open
Keywords: bacterial genomics and functional analysis; genome-wide comparative genomics; bioinformatics methods and tools; metagenomics; metatranscriptomics
(This special issue belongs to the Section Molecular Microbiology)
Mechanisms and Pathophysiology of Obesity
edited by Padmamalini Baskaran
submission deadline 31 Aug 2025 | Viewed by 291 | Submission Open
Keywords: understanding genetic factors for obesity at the molecular level; understanding environmental factors for obesity at the molecular level; contribution of insulin resistance to obesity and ways to combat; circadian misalignment– molecular level understanding of its contribution to obesity and ways to mitigate it; effective and individualized obesity treatment strategies for stress; molecular understanding of the influence of parental obesity on childhood overweight; molecular mechanisms of maternal smoking on childhood obesity; therapeutic interventions for obesity through recombinant hormones; role of gut hormones in the treatment of obesity; development of new digital tools for weight management interventions
(This special issue belongs to the Section Molecular Medicine)
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