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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cardiovascular Disease: From Molecular Mechanisms to Therapeutic Innovations

edited by Andrea Marzullo

submission deadline 31 May 2026 | 9 articles | Viewed by 18338 | Submission Open

Keywords: cardiovascular pathophysiology; molecular biomarkers; inflammation and oxidative stress; therapeutic targets; lipid metabolism

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Therapies and Disease Associations in Diabetes

edited by

Hongbao Cao

and Shaolei Teng

submission deadline 31 May 2026 | 5 articles | Viewed by 12526 | Submission Open

Keywords: diabetes; molecular therapies; comorbidities; genomics; proteomics; metabolomics; multi-omics; precision medicine

(This special issue belongs to the Section Molecular Medicine)

Multiple Myeloma: From Molecular Mechanism to Diagnosis and Therapy

edited by

Jari Intra

submission deadline 31 May 2026 | 5 articles | Viewed by 9983 | Submission Open

Keywords: multiple myeloma; blood cancer; immunopathogenesis; biomarker; immunoglobulin

(This special issue belongs to the Section Molecular Medicine)

Advances in Phytochemical Research: Molecular Pathways in Health and Disease

edited by

Christiana Charalambous

and

Christiana Neophytou

submission deadline 31 May 2026 | 8 articles | Viewed by 8186 | Submission Open

Keywords: phytochemicals; molecular mechanisms; cancer signaling pathways; anti-inflammatory properties; anti-oxidant properties; apoptosis; cardiovascular disorders; metabolic syndromes; chemoprevention

(This special issue belongs to the Section Molecular Medicine)

The Molecular Basis of Immunotherapy in Cancer Treatment

edited by Hassan Dastsooz

submission deadline 31 May 2026 | 3 articles | Viewed by 7268 | Submission Open

Keywords: immunotherapy; cancer; CAR-T cell therapy; monoclonal antibodies; immunomodulation; cytokines; immune evasion mechanisms

(This special issue belongs to the Section Molecular Medicine)

Linking Genomic Changes with Cancer in the NGS Era, 3rd Edition

edited by Javier Azúa-Romeo

submission deadline 31 May 2026 | 8 articles | Viewed by 6863 | Submission Open

Keywords: next-generation sequencing (NGS); genetic variation; driver gene; functional validation; gene editing; cancer

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Novel Pharmacological Strategies and Molecular Mechanisms in Nonclinical Research

edited by

Vanessa Mateus

submission deadline 31 May 2026 | 5 articles | Viewed by 4623 | Submission Open

Keywords: molecular pharmacology; drug targets; signal transduction pathways; nonclinical models; receptor-ligand interactions; pharmacogenomics; preclinical drug development; gene expression modulation; mechanism of action; translational pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Research in Glioblastoma and Neuroblastoma

edited by

Maria G. Bottone

submission deadline 31 May 2026 | 3 articles | Viewed by 3905 | Submission Open

Keywords: glioblastoma; neuroblastoma; neuropharmaceuticals; drug design; blood– brain barrier; molecular therapeutics; brain-tumor biomarkers

(This special issue belongs to the Section Molecular Medicine)

Neuropituitary Hormones in Metabolic Disorders

edited by

Claudia Camerino

submission deadline 31 May 2026 | 2 articles | Viewed by 2957 | Submission Open

Keywords: oxytocin; vasopressin; thermoregulation; obesity; Prader– Willi syndrome; autism spectrum disorder; anorexia nervosa; craniopharyngioma; metabolic disorders; hypothalamic pituitary disorders; oxytocin-deficiency; vasopressin-deficiency

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Mechanisms and Pharmacological Underlying Cardiorenal Diseases

edited by

Caterina Carollo

submission deadline 31 May 2026 | 3 articles | Viewed by 2520 | Submission Open

Keywords: hypertension; cardio-renal syndromes; heart failure; chronic kidney disease; hemodialysis; periotenal dialysis

(This special issue belongs to the Section Molecular Medicine)

Repurposing and Innovation: Drug Research in Neuroprotection

edited by

Stela Dragomanova

submission deadline 31 May 2026 | 2 articles | Viewed by 2304 | Submission Open

Keywords: neuroprotection; drug repurposing; natural-derived compounds; neurodegenerative diseases; pharmacological innovation

(This special issue belongs to the Section Molecular Pharmacology)

Cancer Genetics and Pharmacology: Advancing Precision Therapeutics

edited by Baoming Wang

submission deadline 31 May 2026 | 1 articles | Viewed by 1456 | Submission Open

Keywords: cancer genetics; epigenetic modifications; pharmacogenomics; personalized medicine

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular and Cellular Insights into the Musculoskeletal System, Joints and Spine

edited by Seon-Jin Yoon

submission deadline 31 May 2026 | 2 articles | Viewed by 986 | Submission Open

Keywords: musculoskeletal system; joints; spine; pain-related nerve system; genetics; sequencing; human; animal; cell

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Epithelial Cancers: From Molecular Mechanisms to Therapeutic Innovations

edited by

Cristian Scheau

and

Ana Caruntu

submission deadline 31 May 2026 | 1 articles | Viewed by 711 | Submission Open

Keywords: epithelial cancers human malignancies; tumor microenvironment; genetic alterations; epithelial– mesenchymal transition

(This special issue belongs to the Section Molecular Medicine)

Advances in piRNA Biology and Processing: Mechanisms and Applications

edited by

Yicheng Luo

submission deadline 31 May 2026 | Viewed by 507 | Submission Open

Keywords: piRNA; Piwi; transposable elements; epigenetics; genetics; development; cancer

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Medicinal Plants and Phytochemicals for the Prevention and Intervention of Metabolic Disease and Its Complications

edited by

Sandra Barbalho

submission deadline 31 May 2026 | Viewed by 440 | Submission Open

Keywords: metabolic diseases; phytochemicals; medicinal plants; metabolic diseases complications; functional foods

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Natural Polyphenols in Cardiovascular Disease Prevention: Molecular Mechanisms and Therapeutic Perspectives

edited by

Pasquale Perrone

submission deadline 31 May 2026 | Viewed by 256 | Submission Open

Keywords: polyphenols; phytochemicals; cardiovascular diseases; cardiovascular; protective

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Approaches and Innovations for Human and Veterinary Vaccines

edited by Attila Farsang

submission deadline 31 May 2026 | Viewed by 186 | Submission Open

Keywords: vaccines; vaccinology; immunology mechanisms; vaccine vectors; gene vaccines; infection; host– pathogen interactions and responses

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Targeted Therapies and Biomarker Discovery in Health and Disease

edited by

Rodrigo Pinheiro Araldi

submission deadline 10 Jun 2026 | 3 articles | Viewed by 2013 | Submission Open

Keywords: multi-omics technologies; targeted therapies; biomarkers; oncology; neurology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights: Mechanisms Underlying the Biological Activities of Natural Products—2nd Edition

edited by

Premalatha Balachandran

submission deadline 20 Jun 2026 | 9 articles | Viewed by 11799 | Submission Open

Keywords: natural products; molecular mechanisms; biological activities; pharmacodynamics; drug discovery; therapeutic potential; signaling pathways; target identification; pharmacological properties; bioactive compounds

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

The Green Revolution in Cancer Research: Bioactive Substances from Plants as Promising Therapeutics

edited by Johura Ansary

submission deadline 20 Jun 2026 | 5 articles | Viewed by 9048 | Submission Open

Keywords: bioactive compound; cancer research; plant-derived; anti-cancer properties; therapeutic strategies

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Advancements in Dendrimer Technology: From Molecular Biology Applications to Therapeutic Innovations

edited by

Jørn Bolstad Christensen

submission deadline 20 Jun 2026 | Viewed by 252 | Submission Open

Keywords: dendrimers; molecular biology applications; therapeutic innovations; nanomedicine; drug delivery

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Cancer Biomarkers: Identification and Practical Applications

edited by

Mihaela Chivu-Economescu

submission deadline 30 Jun 2026 | 7 articles | Viewed by 15051 | Submission Open

Keywords: cancer biomarkers; liquid biopsy; early detection; progression; prognosis; treatment monitoring

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Biology Methods in Hepatology Research, 2nd Edition

edited by

Ralf Weiskirchen

and

Dileep G. Nair

submission deadline 30 Jun 2026 | 3 articles | Viewed by 8785 | Submission Open

Keywords: hepatic diseases; molecular biology methods; single-cell genomics; single-cell proteomics; hepatic organoids; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Molecular Functions of Long Non-Coding RNAs: Implications for Diseases and Therapy

edited by

Bodhisattwa Banerjee

submission deadline 30 Jun 2026 | 7 articles | Viewed by 8396 | Submission Open

Keywords: long non-coding RNAs (lncRNAs); gene regulation; molecular mechanisms; chromatin remodeling; epigenetic control; disease pathophysiology; biomarker discovery; therapeutic strategies; translational research

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Breeding and Genetics Research in Plants—3rd Edition

edited by

Shimeles Tilahun

submission deadline 30 Jun 2026 | 10 articles | Viewed by 8370 | Submission Open

Keywords: genetic basis; genomic selection/prediction; molecular breeding; biotic and abiotic stresses; qPCR

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism and Regulation in Neuroinflammation, 2nd Edition

edited by Hung-Pei Tsai

submission deadline 30 Jun 2026 | 2 articles | Viewed by 8233 | Submission Open

Keywords: microglia; glial cells; cytokines; blood– brain barrier; traumatic brain injury; aging; Alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis; multiple sclerosis

(This special issue belongs to the Section Molecular Medicine)

Tumor Immunology: From Molecular Mechanisms to Treatment

edited by

Deepika Awasthi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4632 | Submission Open

Keywords: cellular metabolism; metabolic reprogramming; immunometabolism; tumor microenvironment; immunotherapy; metabolites; immunosuppression; immune cells; tumor cells

(This special issue belongs to the Section Molecular Medicine)

Cancer Immunology: Molecular Tools, New Therapeutic Targets, Challenges, and Opportunities

edited by Pablo C. Ortiz-Lazareno

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3565 | Submission Open

Keywords: cancer immunology; immune response; immune evasion; immune checkpoints; immune response

(This special issue belongs to the Section Molecular Medicine)

Natural Products in Biomedicine and Pharmacotherapy, 2nd Edition

edited by

Ahmed Ezat El Zowalaty

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3137 | Submission Open

Keywords: natural products; genetic engineering; pharmacotherapy; anticancer; antimicrobials

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Biology in Drug Design and Precision Therapy, 2nd Edition

edited by

Cristina Manuela Dragoi

Ion-Bogdan Dumitrescu

and

Alina Crenguta Nicolae

submission deadline 30 Jun 2026 | 4 articles | Viewed by 2125 | Submission Open

Keywords: molecular biology; drug design; molecular targets; disease mechanisms; structural biology; computational chemistry; pharmacology; precision medicine; molecular pathways; personalized therapy; drug research

(This special issue belongs to the Section Molecular Medicine)

Future Challenges of Targeted Therapy of Cancers, 3rd Edition

edited by

Simona Gurzu

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1667 | Submission Open

Keywords: biomarkers; tumor tissue; individualized therapy; gene profile; epithelial– mesenchymal transition; immunotherapy; angiogenesis; metastases; oncology; pathology

(This special issue belongs to the Section Molecular Medicine)

Molecular and Omics Insights into Microbiome–Host Interactions in Health and Disease

edited by

Shweta Kuba

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1103 | Submission Open

Keywords: microbiome; host– microbe interactions; multi-omics; molecular mechanisms; health and disease

(This special issue belongs to the Section Molecular Microbiology)

Design and Synthesis of Bioactive Peptides and Molecular Conjugates for Targeted Drug Delivery

edited by

Ashmeet Singh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1089 | Submission Open

Keywords: peptides; non-covalent synthesis; fluorescent probes; biomaterials; stimuli-responsive; hydrogels; site specific; drug delivery

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Advances in Bioactive Molecules and Modern Structure–Activity Approaches

edited by

Claudiu N. Lungu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 954 | Submission Open

Keywords: QSAR; structure– activity modeling; drug design

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Emerging Trends in Nanobiotechnology and Nanomedicine

edited by

Eduardo Ricci Junior

and

Ana Paula Dos Santos Matos

submission deadline 30 Jun 2026 | 1 articles | Viewed by 870 | Submission Open

Keywords: bionanotechnology; nanocarriers; cancer; infectious diseases; drug delivery; bioavailability

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Cerebrovascular Diseases: From Pathogenesis to Treatment, 2nd Edition

edited by

Adrià Arboix

Teresa Gasull

and Francisco Purroy

submission deadline 30 Jun 2026 | 1 articles | Viewed by 829 | Submission Open

Keywords: stroke; ischemic; hemorrhagic; neuronal death; molecular mechanisms; inflammation; epigenetics; ischemic tolerance; ferroptosis; free radicals; treatment

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms in Plant Stress Tolerance, 2nd Edition

edited by

Sajid Ali

submission deadline 30 Jun 2026 | 1 articles | Viewed by 641 | Submission Open

Keywords: plant stress tolerance; molecular mechanisms; stress-responsive gene; signal transduction pathways; epigenetic modifications; phytohormones (ethylene; ABA; SA; JA); reactive oxygen species (ROS); plant– microbe interactions; microbial plant bio-stimulants; omics approaches (genomics; transcriptomics; proteomics; and metabolomics)

(This special issue belongs to the Section Molecular Plant Sciences)

New Discoveries and Mechanistic Insights in Future Cancer Therapies

edited by

Yi-Chiang Hsu

submission deadline 30 Jun 2026 | Viewed by 535 | Submission Open

Keywords: cancer therapeutics; tumor antigens; vaccine; nanotechnology

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Abiotic and Biotic Stress Tolerance in Crops

edited by

Abdullah Shalmani

and

Adnan Iqbal

submission deadline 30 Jun 2026 | 1 articles | Viewed by 497 | Submission Open

Keywords: stress tolerance; molecular mechanisms; omics approaches; transcriptional regulation; multi-stress resistance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Novel Anticancer Drugs: From Structure to Molecular Targets

edited by

Magdalena Mizerska-Kowalska

and

Roman Paduch

submission deadline 30 Jun 2026 | Viewed by 236 | Submission Open

Keywords: cancer therapy; anticancer agents; natural sources; drug design; drug repurposing; drug synthesis; molecular mechanisms

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Mechanisms of Plant Resistance and Sensitivity to Biotic and Abiotic Factors: The Role and Function of Sex

edited by

Ekaterina N. Baranova

submission deadline 30 Jun 2026 | Viewed by 223 | Submission Open

Keywords: plant reproductive development; molecular regulation of sex; apomixis; dioecious plants; hermaphrodites; pollination; female and male gametophyte; regulation of flowering; plant sex-determining genes; evolution towards dioecy

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Fruit Development, Stress Response, and Quality Formation in Horticultural Crops

edited by

Rahat Sharif

submission deadline 30 Jun 2026 | Viewed by 218 | Submission Open

Keywords: phytohormones; fruit development; abiotic stress; pathogen resistance; epigenetics; metabolic pathways; postharvest biology

(This special issue belongs to the Section Molecular Plant Sciences)

Phytochemicals in Cancer Chemoprevention and Treatment: 2nd Edition

edited by

Wojciech Trybus

Ewa Trybus

and

Aneta Wȩgierek-Ciuk

submission deadline 20 Jul 2026 | 4 articles | Viewed by 16504 | Submission Open

Keywords: phytochemicals; chemoprevention; cancer therapy; oxidative stress; apoptosis; autophagy; mitotic catastrophe; cell cycle; cytotoxicity; DNA damage; molecular pathways

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Product in Skin Inflammation and Barrier Function Damage

edited by

Hsiu-Mei Chiang

submission deadline 20 Jul 2026 | 3 articles | Viewed by 11431 | Submission Open

Keywords: skin inflammation; barrier function damage; natural compounds; antioxidant properties; antiaging

(This special issue belongs to the Section Molecular Medicine)

Modulation of Oxidative Stress: A Global Perspective for Climate Change Adaptation

edited by

Tihomir Kovač

and

Tihana Marček

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1168 | Submission Open

Keywords: oxidative stress; modulation; climate change; environmental factors; adaption

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Innovative Strategies in Overcoming Antimicrobial Resistance: From Phage Therapy to Combination

edited by Rajnikant Sharma

submission deadline 20 Jul 2026 | Viewed by 269 | Submission Open

Keywords: bacteriophages; phage therapy; antimicrobial resistance; phage engineering; phage-antibiotic combination; phage pharmacokinetics

(This special issue belongs to the Section Molecular Microbiology)

Oral Cancer: Prophylaxis, Etiopathogenesis and Treatment, 2nd Edition

edited by

Violeta Popovici

and

Emma Adriana Ozon

submission deadline 31 Jul 2026 | 4 articles | Viewed by 11520 | Submission Open

Keywords: oral carcinogenesis; biomarkers; cell signaling; natural products; phytochemicals; medicinal plants; essential oils; antimicrobial activity; cytotoxicity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Food-Derived Natural Products and Their Biological Activities—2nd Edition

edited by

Yanfang Li

submission deadline 31 Jul 2026 | 6 articles | Viewed by 9201 | Submission Open

Keywords: food compounds; natural products; biologically active compounds; oxidative stress; anticancer; functionality of foods

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Phytochemicals: Therapeutic Potential in Metabolic Disorders and Cancer

edited by

Mohamed Addi

submission deadline 31 Jul 2026 | 2 articles | Viewed by 6319 | Submission Open

Keywords: phytochemicals; molecular mechanisms; cancer therapeutics; metabolic disorders; natural compounds; signal transduction; epigenetic regulation; oxidative stress; anti-inflammatory agents; plant-based

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

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