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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Strategies for Improved Crop Performance
edited by Maria Oszvald
submission deadline 10 Jul 2025 | Viewed by 172 | Submission Open
Keywords: wheat genome; plant breeding; crop improvement; candidate genes; genetic engineering
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanism and Advances in Gynecological Pathology: From Bench to Bedside
edited by
submission deadline 20 Jul 2025 | Viewed by 284 | Submission Open
Keywords: gynecological cancers; molecular pathology; biomarkers; genetic alterations; epigenetics; tumor microenvironment; personalized medicine; targeted therapy; endometriosis; ovarian cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Pharmacological Activities and Mechanisms of Action of Natural Products
edited by , and Lee Simon Ming-Yuen
submission deadline 31 Jul 2025 | 13 articles | Viewed by 17491 | Submission Open
Keywords: natural products; pharmacological activity; molecular mechanisms; therapeutic targets; structure– activity relationships; protein– ligand interactions; cell signaling pathways; enzyme inhibition/activation; molecular targets
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Biology in Drug Design and Precision Therapy submission deadline 31 Jul 2025 | 9 articles | Viewed by 12379 | Submission Open
Keywords: molecular biology; drug design; molecular targets; disease mechanisms; structural biology; computational chemistry; pharmacology; precision medicine; molecular pathways; personalized therapy; drug research
(This special issue belongs to the Section Molecular Medicine)
Infectious Diseases and Molecular Epidemiology: A Focus on Pathogenic Microorganisms
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 12189 | Submission Open
Keywords: infectious disease; malaria; meningitis; pathogene
(This special issue belongs to the Section Molecular Microbiology)
Cellular and Molecular Biology Insights into Neurodegenerative Diseases: From Pathogenesis to Therapeutic Targets submission deadline 31 Jul 2025 | 5 articles | Viewed by 8838 | Submission Open
Keywords: neurodegenerative disease; oxidative stress; ER stress; mitochondrial stress; corrector; misfolding protein; preoteostasis; neuroblastoma
(This special issue belongs to the Section Molecular Medicine)
Exosomes in Tissue Regeneration and Disease Therapy
edited by
submission deadline 31 Jul 2025 | 5 articles | Viewed by 7708 | Submission Open
Keywords: exosomes; tiny vesicles; cell-specific proteins; exosome-mediated; human diseases
(This special issue belongs to the Section Molecular Medicine)
Molecular Breeding and Genetics Research in Plants, 2nd Edition
edited by
submission deadline 31 Jul 2025 | 7 articles | Viewed by 7308 | Submission Open
Keywords: genetic basis; genomic selection/prediction; molecular breeding; biotic and abiotic stresses; qPCR
(This special issue belongs to the Section Molecular Plant Sciences)
Neuropharmacology and Brain Physiology: From Molecular Mechanisms to Medicines Application
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 6125 | Submission Open
Keywords: neuropsychopharmacology; neurotransmitters; neuropeptides; receptor proteins; agonist; competitive antagonist; non-competitive antagonist
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanism of Plant Growth, Development and Secondary Metabolism
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 5371 | Submission Open
Keywords: secondary metabolites; plant defense; signaling and adaptation mechanisms; plant development; genetic and epigenetic regulation; plant physiology
(This special issue belongs to the Section Molecular Plant Sciences)
Radiation-Induced Cellular and Molecular Responses
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 5362 | Submission Open
Keywords: radiation; radiobiology; space radiobiology; heavy ions carcinogenesis; LinearNonTreshold; radionuclide therapy; alpha emitters; beta emitters; radiobiology
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms in Plant Stress Tolerance
edited by
submission deadline 31 Jul 2025 | 5 articles | Viewed by 3413 | Submission Open
Keywords: plant stress tolerance; molecular mechanisms; stress-responsive gene; signal transduction pathways; epigenetic modifications; phytohormones (ethylene; ABA; SA; JA); reactive oxygen species (ROS); plant– microbe interactions; microbial plant bio-stimulants; omics approaches (genomics; transcriptomics; proteomics; and metabolomics)
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity
edited by Bogdana Virgolici
submission deadline 31 Jul 2025 | 4 articles | Viewed by 3010 | Submission Open
Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction
(This special issue belongs to the Section Molecular Medicine)
Epithelial Cancers: Molecular Mechanisms, Diagnostic Innovations, and Therapeutic Advances
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2634 | Submission Open
Keywords: epithelial cancers; molecular mechanisms; genetic alterations; epigenetics; tumor microenvironment; epithelial-mesenchymal transition; biomarkers; liquid biopsy; imaging technologies; targeted therapies; immunotherapies; personalized medicine; treatment resistance; cancer recurrence; translational research
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2219 | Submission Open
Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 2nd Edition
edited by Haibo Dong and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 1734 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions
(This special issue belongs to the Section Molecular Medicine)
Angiogenesis in Diseases: Molecular Mechanism and Regulation submission deadline 31 Jul 2025 | 1 articles | Viewed by 1443 | Submission Open
Keywords: blood vessels; angiogenic factors; trophic factors; angiogenesis biomarkers; cancers; heart diseases
(This special issue belongs to the Section Molecular Medicine)
Exploring Molecular Pathways in Skin Health and Diseases
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1176 | Submission Open
Keywords: skin health; skin aging; skin disease; molecular pathways; oxidative stress; immune response; inflammatory skin diseases
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Molecular Basis of Immunotherapy in Cancer Treatment
edited by Hassan Dastsooz
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1096 | Submission Open
Keywords: immunotherapy; cancer; CAR-T cell therapy; monoclonal antibodies; immunomodulation; cytokines; immune evasion mechanisms
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Cancer Biomarkers: Identification and Practical Applications submission deadline 31 Jul 2025 | 2 articles | Viewed by 988 | Submission Open
Keywords: cancer biomarkers; liquid biopsy; early detection; progression; prognosis; treatment monitoring
(This special issue belongs to the Section Molecular Medicine)
Molecular and Pharmacological Insights into Bioactive Compounds: Pathways to Therapeutics submission deadline 31 Jul 2025 | 1 articles | Viewed by 620 | Submission Open
Keywords: bioactive compounds; natural products; drug discovery; pharmacology; therapeutic pathways; molecular mechanisms; signal transduction; medicinal chemistry; target identification
(This special issue belongs to the Section Molecular Pharmacology)
Tumor Microenvironment: Crosstalk Between Epigenetics, Metabolism and Immunity
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 581 | Submission Open
Keywords: tumor microenvironment; epigenetic modifications; metabolic reprogramming; immune escape; tumor metastasis; therapeutic resistance
(This special issue belongs to the Section Molecular Medicine)
The Molecular Basis of Genetic and Epigenetic Changes in Cancer
edited by Su Yon Jung
submission deadline 31 Jul 2025 | Viewed by 320 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; epigenome; DNA methylation; biomarkers; gene expression; proteomics; cancer(s); prediction; prevention; screening; prognosis; treatment; infection; COVID-19; interaction with the environment; occupational hazard
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Advances in piRNA Biology and Processing: Mechanisms and Applications
edited by
submission deadline 31 Jul 2025 | Viewed by 297 | Submission Open
Keywords: piRNA; Piwi; transposable elements; epigenetics; genetics; development; cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 238 | Submission Open
Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19
(This special issue belongs to the Section Molecular Medicine)
Advances in Molecular Therapies and Disease Associations in Diabetes
edited by and Shaolei Teng
submission deadline 31 Jul 2025 | Viewed by 208 | Submission Open
Keywords: diabetes; molecular therapies; comorbidities; genomics; proteomics; metabolomics; multi-omics; precision medicine
(This special issue belongs to the Section Molecular Medicine)
Autophagy and the Ubiquitin–Proteasome System: Regulators of Protein Homeostasis, Cell Death, and Disease Pathogenesis
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 206 | Submission Open
Keywords: autophagy; ubiquitin– proteasome system; protein homeostasis; autophagosome; cell death regulation; cancer; Alzheimer's disease
(This special issue belongs to the Section Molecular Medicine)
Omics Technologies and Genomic Studies Unraveling Alzheimer’s Disease Heterogeneity
edited by
submission deadline 31 Jul 2025 | Viewed by 109 | Submission Open
Keywords: Alzheimer; multi-omics approaches; heterogeneity; genetic loci and biomarkers; neurodegenerative disease research
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Epigenetics and Chromatin Remodeling in Cancer
edited by
submission deadline 31 Jul 2025 | Viewed by 88 | Submission Open
Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy
(This special issue belongs to the Section Molecular Medicine)
Phagocytosis in Neurological Disorders: Molecular Mechanisms and Therapeutic Targets
edited by and Konstantinos Anagnostopoulos
submission deadline 31 Jul 2025 | Viewed by 71 | Submission Open
Keywords: phagocytosis; endothelial cells; microglial cells; stroke; dementia; inflammation
(This special issue belongs to the Section Molecular Medicine)
Exploring Symmetry and Asymmetry in Molecular Design for Anticancer and Antioxidant Therapies
edited by
submission deadline 20 Aug 2025 | Viewed by 112 | Submission Open
Keywords: symmetry; asymmetry; antioxidant; anticancer; synergy; oxidative stress; cytotoxicity; molecular design; synthesis
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Research in Chronic Dermatoses, 2nd Edition submission deadline 31 Aug 2025 | 2 articles | Viewed by 11550 | Submission Open
Keywords: dermatopathology; dermatosurgery; skin biology; molecular biology; genetics; JAK inhibitors; antibodies
(This special issue belongs to the Section Molecular Medicine)
The Role of Neuroinflammation in Neurodegenerative Diseases
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 8694 | Submission Open
Keywords: molecular neuropathology; neuroinflammation; multiple sclerosis; neurodegenerative diseases; dementias
(This special issue belongs to the Section Molecular Medicine)
Metabolic Interactions Between the Gut Microbiome and Organism
edited by Sree V. Chintapalli
submission deadline 31 Aug 2025 | 3 articles | Viewed by 8185 | Submission Open
Keywords: microbiota dysbiosis; metabolism; inflammation; gut– brain axis; metabolic interactions
(This special issue belongs to the Section Molecular Microbiology)
Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 8025 | Submission Open
Keywords: natural products; natural product derivatives; antidiabetic agents; α -glucosidase inhibitors; amylase inhibitors; PTP1B inhibitors; DPP-4 inhibitors; molecular level; kinetic studies; in vitro studies; in vivo studies; computational methods; mode of action
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Recombinant Proteins for Molecular Biology Research: Technologies and Applications submission deadline 31 Aug 2025 | 5 articles | Viewed by 7342 | Submission Open
Keywords: recombinant proteins; vaccine; intra-cellular signaling factors; membrane proteins; drug targets
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Insights and Therapeutic Advances in Hematological Disorders
edited by
submission deadline 31 Aug 2025 | 6 articles | Viewed by 6709 | Submission Open
Keywords: acute leukemia; myeloproliferative neoplasms; lymphoma; multiple myeloma; hemoglobinopathies; hemophilia
(This special issue belongs to the Section Molecular Medicine)
Network Pharmacology, Multi-targets and Receptor–Receptor Interactions in the CNS submission deadline 31 Aug 2025 | 3 articles | Viewed by 6706 | Submission Open
Keywords: network pharmacology; multi-targets; receptor– receptor interactions; target proteins; drug therapy in CNS; receptors
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms in Demyelinating Disorders and Remyelination Strategies of the CNS submission deadline 31 Aug 2025 | 4 articles | Viewed by 6125 | Submission Open
Keywords: demyelination; molecular mechanisms; oligodendrocyte precursor cells; myelinogenesis; dysmyelination; lipid metabolism; microglia and macrophages; experimental autoimmune encephalomyelitis; biomarkers; remyelination
(This special issue belongs to the Section Molecular Medicine)
Linking Genomic Changes with Cancer in the NGS Era, 2nd Edition
edited by Javier Azúa-Romeo and
submission deadline 31 Aug 2025 | 4 articles | Viewed by 5240 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; driver gene; functional validation; gene editing; cancer
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Advanced Molecular Research on Hypertensive Disorders of Pregnancy (HDPs)
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 4975 | Submission Open
Keywords: DNA; RNA; protein; microbiome; hypertensive disorders of pregnancy; preeclampsia; epidemiology; meta-analysis
(This special issue belongs to the Section Molecular Medicine)
Editorial Board Members' Collection Series: Natural Product Pharmacology submission deadline 31 Aug 2025 | 1 articles | Viewed by 3478 | Submission Open
Keywords: natural compounds; bioactive molecules; molecular mechanisms; therapeutic targets; drug discovery; pharmacokinetics; pharmacodynamics; cellular signaling pathways
(This special issue belongs to the Section Molecular Pharmacology)
Innovative Strategies and Applications for Drug Discovery
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3260 | Submission Open
Keywords: drug discovery; computational strategies; molecular docking; pharmacophore modeling; molecular dynamics simulations
(This special issue belongs to the Section Molecular Medicine)
Genomic Analysis of Common Disease, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 2989 | Submission Open
Keywords: genomic analysis; microarray analysis; whole exome sequencing; pathogenic mutations; copy number variants; DNA sequence variation; intellectual disability; autism; connective tissue dysplasia
(This special issue belongs to the Section Molecular Medicine)
Cancer Biomarkers: Discovery and Applications
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2891 | Submission Open
Keywords: cancer biomarkers; precision medicine; prevention; prognosis; diagnosis
(This special issue belongs to the Section Molecular Medicine)
Mental Disorder: Focus on Pathogenesis to Treatment
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 2328 | Submission Open
Keywords: mental disorders; neurobiological; oxidative stress; neuroinflammation; gene variants
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Food-Derived Natural Products and Their Biological Activities—2nd Edition
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1632 | Submission Open
Keywords: food compounds; natural products; biologically active compounds; oxidative stress; anticancer; functionality of foods
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Unraveling the Molecular Marvels of Heart Repair and Regeneration
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1442 | Submission Open
Keywords: cardiac repair; angiogenesis; heart failure; ischemia; reperfusion; reactive oxygen; cell therapy; exosome therapy; gene therapy; apoptosis; ischemic preconditioning; gene editing
(This special issue belongs to the Section Molecular Medicine)
Hormonal Regulation in Germ Cell Development
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1406 | Submission Open
Keywords: spermatogenesis; steroidogenesis; sex hormones; sex hormone receptors; gonadotropin; germ cell differentiation; androgen; luteinizing hormone; follicle-stimulating hormone; glycoprotein hormone receptors
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Significance of Transcription Factors, miRNAs, and lncRNAs in Anticancer Drug Development, 2nd Edition submission deadline 31 Aug 2025 | 3 articles | Viewed by 1390 | Submission Open
Keywords: transcription factors; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); anticancer drugs; cancer; coactivators
(This special issue belongs to the Section Molecular Medicine)
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