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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Thoracic Surgery: Technology and Innovation

edited by

Yoshikane Yamauchi

submission deadline 30 Jun 2026 | Viewed by 25 | Submission Open

Keywords: thoracic surgery; robotic surgical procedures; video-assisted thoracoscopic surgery; thoracic neoplasms; minimally invasive surgical procedures; surgical outcomes; lung cancer surgery; surgical innovation

(This special issue belongs to the Section Methods and Technologies Development)

Research and Treatment of Hepatocellular Carcinoma

edited by Chung Cheung Thomas Yau

submission deadline 30 Jun 2026 | Viewed by 23 | Submission Open

Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments

(This special issue belongs to the Section Cancer Therapy)

Advances in Clinical Treatment of Pancreatic Cancers

edited by

Alberto Brolese

submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open

Keywords: pancreatic cancer; PDAC; neoadjuvant chemotherapy; neuroendocrine tumors; pNET; pancreatic cystic disease; IPMN; pancreatic oligometastases

(This special issue belongs to the Section Clinical Research of Cancer)

Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)

edited by Yi Huang and

Bing Li

submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open

Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Basic and Translational Science in Ocular Oncology

edited by Anthony B. Daniels,

Arun D. Singh

and

Jens Folke Kiilgaard

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: ocular oncology; eye cancer; tumors; melanoma; retinoblastoma; hemangioma; hemangioblastoma; lymphoma

(This special issue belongs to the Section Cancer Pathophysiology)

Circadian Rhythms, Cancers and Chronotherapy (2nd Edition)

edited by

Francis Levi

Pasquale F. Innominato

and Esra Tasali

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: drug development and chronotherapy; chemotherapy; immunotherapy; targeted agents; radiotherapy; surgery; circadian host or tumor biomarkers; electronic patient-reported outcomes; circadian rhythms and sleep; sex- and age specificities; clinical trial designs; mathematical models and artificial intelligence; digital healthcare; telemedicine and logistics

(This special issue belongs to the Section Cancer Therapy)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | Viewed by 16 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | Viewed by 12 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Myeloma and Immunology

edited by

Joao Cristina

submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open

Keywords: multiple myeloma; tumor immunology; immune microenvironment; immunotherapy; CAR-T cells; immune evasion; immune profiling

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | Viewed by 6 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Therapeutic Strategies for Prostate Cancer

edited by Angelo Naselli and

Giacomo Maria Pirola

submission deadline 1 Jul 2026 | 4 articles | Viewed by 10898 | Submission Open

Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies

(This special issue belongs to the Section Cancer Therapy)

The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms

edited by

Elisa Meacci

submission deadline 1 Jul 2026 | 3 articles | Viewed by 5622 | Submission Open

Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer

(This special issue belongs to the Section Cancer Therapy)

Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments

edited by Christian Ott and Julius Höhne

submission deadline 1 Jul 2026 | 3 articles | Viewed by 3887 | Submission Open

Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy

(This special issue belongs to the Section Cancer Therapy)

The Mediastinum—Pandora’s Box

edited by

Cesar A. Moran

submission deadline 1 Jul 2026 | Viewed by 384 | Submission Open

Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors

Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment

edited by

Nethaji Muniraj

submission deadline 1 Jul 2026 | Viewed by 52 | Submission Open

Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Perioperative Management and Cancer Outcome (2nd Edition)

edited by

Daniela Ionescu

submission deadline 9 Jul 2026 | Viewed by 30 | Submission Open

Keywords: perioperative management; cancer treatment outcomes; onco-anesthesiology; preoperative risk assessment; enhanced recovery after surgery (ERAS); pain management; personalized medicine

Clinicopathological Study of Gynecologic Cancer (2nd Edition)

edited by

Massimo Origoni

submission deadline 10 Jul 2026 | 1 articles | Viewed by 777 | Submission Open

Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology

(This special issue belongs to the Section Clinical Research of Cancer)

Chemotherapy for Metastatic Head and Neck Squamous Cell Carcinomas

edited by Ken Saijo

submission deadline 15 Jul 2026 | Viewed by 48 | Submission Open

Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy

(This special issue belongs to the Section Cancer Metastasis)

Tumor Microenvironment of Breast Cancer–2nd Edition

edited by

Masanori Oshi

submission deadline 15 Jul 2026 | Viewed by 23 | Submission Open

Keywords: breast cancer; tumor microenvironment; TME; stromal cells

(This special issue belongs to the Section Tumor Microenvironment)

Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management

edited by

Mateusz Czajkowski

and Marcin Matuszewski

submission deadline 15 Jul 2026 | Viewed by 16 | Submission Open

Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Hodgkin Lymphoma (HL)

edited by

Antonino Carbone

submission deadline 15 Jul 2026 | Viewed by 9 | Submission Open

Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL

(This special issue belongs to the Section Cancer Pathophysiology)

Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 20 Jul 2026 | 1 articles | Viewed by 214 | Submission Open

Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers

(This special issue belongs to the Section Cancer Therapy)

HIV-Associated Lymphoid Neoplasms (2nd Edition)

edited by

José-Tomás Navarro

submission deadline 20 Jul 2026 | Viewed by 25 | Submission Open

Keywords: B-cell lymphoma; HIV; AIDS; Epstein– Barr virus; epidemiology; pathogenesis; prognosis

(This special issue belongs to the Section Infectious Agents and Cancer)

Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and Senthamizhchelvan Srinivasan

submission deadline 25 Jul 2026 | Viewed by 20 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Evolving Understanding of the Epidemiology of Thyroid Cancer

edited by

Marco Capezzone

and

Anello Marcello Poma

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3251 | Submission Open

Keywords: thyroid cancer; epidemiology; incidence; time trends; mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Clinical Treatment and Prognosis of Breast Cancer

edited by Roxana Popescu and

Ionut Marcel Cobec

submission deadline 31 Jul 2026 | Viewed by 391 | Submission Open

Keywords: breast cancer; targeted therapy; personalized therapy; alternative approach; tumor biology; gynecologic oncology

Recent Developments on PET-CT in Multiple Myeloma

edited by Carmelo Caldarella

submission deadline 31 Jul 2026 | Viewed by 96 | Submission Open

Keywords: PET/CT; multiple myeloma; novel radiopharmaceuticals; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice—2nd Edition

edited by

Dario Bugada

submission deadline 31 Jul 2026 | Viewed by 32 | Submission Open

Keywords: perioperative care; cancer anesthesia; analgesia; pain management

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

The Emerging Role of Multiplexed Imaging for Cancer Diagnosis and Therapy (2nd Edition)

edited by

Li Liu

and

Yicheng Ni

submission deadline 31 Jul 2026 | Viewed by 31 | Submission Open

Keywords: multiplexed imaging; cancer diagnosis; molecular imaging; novel contrast agents; targeted radionuclide tracers theragnostics; personalized cancer therapy; therapeutic monitoring; imaging biomarkers; clinical translation

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Clinical Trials for Hepatobiliary and Pancreatic Cancer Diagnosis and Treatment (2nd Edition)

edited by

Takuji Okusaka

submission deadline 31 Jul 2026 | Viewed by 29 | Submission Open

Keywords: biliary cancer; liver cancer; pancreatic cancer; clinical trial; diagnosis; surgery; neoadjuvant therapy; adjuvant therapy; radiotherapy; chemotherapy; targeted therapy; precision medicine; immunotherapy; biliary and duodenal stent; psycho-oncology; palliative and supportive care

(This special issue belongs to the Section Clinical Research of Cancer)

Circulating Tumor Cells (CTCs) (2nd Edition)

edited by

Dario Marchetti

submission deadline 31 Jul 2026 | Viewed by 27 | Submission Open

Keywords: liquid biopsy; metastatic biomarkers; CTCs isolation technologies; tumor heterogeneity; clinical CTC applications

(This special issue belongs to the Section Tumor Microenvironment)

Hematopoietic Stem Cells and Cancer Immunotherapy

edited by Harinad B. Maganti

submission deadline 31 Jul 2026 | Viewed by 13 | Submission Open

Keywords: hematopoietic stem cell; transplantation; leukemia; cell biology; CAR-T cell therapies; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Mechanisms of Therapy Resistance in Cancers—2nd Edition

edited by

Birandra K. Sinha

submission deadline 31 Jul 2026 | Viewed by 10 | Submission Open

Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance

(This special issue belongs to the Section Cancer Drug Development)

Novel Therapies in Metastatic Castration-Resistant Prostate Cancer

edited by Kathryn E. Meier

submission deadline 1 Aug 2026 | 1 articles | Viewed by 2874 | Submission Open

Keywords: signal transduction inhibitors; targeted therapies; immunotherapy; radiopharmaceuticals; PARP inhibitors; biomarker-based approaches

(This special issue belongs to the Section Cancer Therapy)

Immunotherapy for Hematologic Malignancies

edited by Rajesh Ramakrishnan Nair

submission deadline 15 Aug 2026 | Viewed by 7 | Submission Open

Keywords: immune evasion; immunotherapy; CAR-T cell therapy; BiTEs; immunomodulators; checkpoint; inhibitors; bone marrow microenvironment; refractory/relapsed; drug resistance; gene editing

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Rare Cancers, Diagnostic Challenges and Personalized Therapeutic Approaches in the 21st Century (2nd Edition)

edited by

Jason Roszik

submission deadline 20 Aug 2026 | 1 articles | Viewed by 547 | Submission Open

Keywords: rare cancer; biology; diagnosis; classification; personalized therapeutics; markers

(This special issue belongs to the Section Cancer Therapy)

Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology

edited by

John Ross Crawford

and Michael Levy

submission deadline 20 Aug 2026 | Viewed by 67 | Submission Open

Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy

(This special issue belongs to the Section Pediatric Oncology)

Socio-Demographic Factors and Cancer Research: 2nd Edition

edited by

Mitchell S. Fourman

and Amanda N. Goldin

submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open

Keywords: socio-economic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis

edited by

Ming Tan

and

Evgeniy V. Denisov

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1143 | Submission Open

Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Hereditary Cancer: State of the Art

edited by Joanne Ngeow, Jianbang Chiang and

Rashid N. Lui

submission deadline 31 Aug 2026 | Viewed by 72 | Submission Open

Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance

(This special issue belongs to the Section Cancer Pathophysiology)

Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact

edited by Jun-Pyo Myong

submission deadline 31 Aug 2026 | Viewed by 4 | Submission Open

Keywords: occupational exposure; chemical carcinogens; risk assessment; epidemiology; biomarkers; exposure assessment; preventive strategies; workplace safety; occupational health; regulatory measures

(This special issue belongs to the Section Infectious Agents and Cancer)

Cancer-Therapy-Related Adverse Events (2nd Edition)

edited by

Yinghong Wang

and Pauline Funchain

submission deadline 1 Sep 2026 | Viewed by 36 | Submission Open

Keywords: cancer; cancer therapy; toxicities; adverse events

(This special issue belongs to the Section Cancer Therapy)

The Role of Minimally Invasive and Minimally Radical Surgery in Cervical and Endometrial Cancer

edited by

Raj Naik

, Marie Plante, Christophe Pomel,

Roberto Tozzi

and Gwénaël Ferron

submission deadline 1 Sep 2026 | Viewed by 26 | Submission Open

Keywords: cervical cancer; endometrial cancer; laparoscopic surgery; minimally invasive surgery; surgical oncology; fertility-sparing surgery; non-radical surgery; conservative surgery

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer: Immune Response, Immune Microenvironment, and Immunotherapy

edited by

Ravindra Deshpande

and

Ann Richmond

submission deadline 15 Sep 2026 | Viewed by 3 | Submission Open

Keywords: breast cancer; immune response; tumor immune microenvironment; immunotherapy resistance; intrinsic and extrinsic mechanisms; immune checkpoint inhibitors; T-cell dysfunction; cytokines; cancer vaccines; tumor immunosuppression

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Novel Advancements in Prostate Cancer Surgery: Indications and Techniques

edited by Valerio Santarelli and

Alessandro Sciarra

submission deadline 30 Sep 2026 | 1 articles | Viewed by 572 | Submission Open

Keywords: radical prostatectomy; prostate cancer; technology; minimally invasive surgery

(This special issue belongs to the Section Cancer Therapy)

Targeting RNA to Improve Cancer Precision Medicine

edited by

Gabriella Misso

, Anna Grimaldi and Chiara Tammaro

submission deadline 30 Sep 2026 | Viewed by 428 | Submission Open

Keywords: cancer; RNA therapy; RNA delivery; RNA; miRNA; mRNA; siRNA; oligonucleotides; aptamers; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma

edited by

Norihiro Imai

and

Dongming Liu

submission deadline 30 Sep 2026 | Viewed by 112 | Submission Open

Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent

(This special issue belongs to the Section Cancer Biomarkers)

Cancer Immunotherapy-Related Adverse Events and Therapy-Related Accelerated Aging

edited by

Grace Lu-Yao

submission deadline 30 Sep 2026 | Viewed by 79 | Submission Open

Keywords: immune-related adverse events (irAEs); accelerated aging; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Development of Effective Therapy Targeting the Microenvironment of Cancer (2nd Edition)

edited by

Moriaki Kusakabe

and Kanae Taruno

submission deadline 30 Sep 2026 | Viewed by 65 | Submission Open

Keywords: cancer; tumor microenvironment; cancer therapy; cancer cell; animal level

(This special issue belongs to the Section Tumor Microenvironment)

Tumor-Initiating Cells in Cancer: Their Interactions with Other Cell Types, and Prospective Applications

edited by

Spiros Vlahopoulos

submission deadline 30 Sep 2026 | Viewed by 36 | Submission Open

Keywords: cancer stem cells; cancer stem-like cells; leukemia; chromatin; transcription factors; cellular phenotype; microenvironment; immunity; tumor stroma

(This special issue belongs to the Section Tumor Microenvironment)

Displaying special issue 1051-1100 on page 22 of 23.

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