The Future of Cancer Immunotherapy: Biomarkers, Tumor Microenvironment, and Precision Medicine
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 32
Special Issue Editor
Interests: pancreatic cancer; Immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a complex and diverse disease influenced by genetic, environmental, and lifestyle factors. Despite significant progress in medical science, it remains one of the leading causes of death worldwide, affecting millions of people every year. Standard treatments for various cancer types, which include surgery, radiotherapy, and chemotherapy, have shown limited success. This highlights the urgent need for the development of new therapies. Recently, there has been a growing emphasis on immunotherapy and personalized medicine as promising strategies for more effectively combating cancer. Current immune checkpoint inhibitors and CAR T-cell therapies face challenges, especially in the treatment of solid tumors. This underscores the necessity for additional clinical biomarkers to identify new therapeutic targets within the realm of personalized medicine. With the advent of high-throughput techniques, both genomics and proteomics have become crucial for identifying mutations that drive tumor initiation and progression, as well as for discovering relevant biomarkers for chemotherapy and immunotherapy. Additionally, proteomic profiling of hematological malignancies and solid tumors will provide deeper insights into the intrinsic and extrinsic factors that shape the tumor microenvironment. This knowledge will facilitate the customization of personalized medicine for various cancer types. By leveraging our current understanding of immunotherapy and conducting genomic and proteomic analyses of cancer patient samples, we can uncover new targets that can aid in the development of novel therapies. Ultimately, this approach aims to enhance life expectancy for cancer patients.
Dr. Aftab Alam
Guest Editor
Manuscript Submission Information
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Keywords
- immunotherapy
- genomics
- proteomics checkpoint
- CAR T cells
- predictive biomarkers
- resistance mechanisms
- combination approaches
- tumor microenvironment
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