Biomolecules

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Genetics and Molecular Breeding in Plants: Advances, Applications, and Future Directions

edited by Yurong Xie and Hongbin Wei

submission deadline 31 Dec 2025 | Viewed by 22 | Submission Open

Keywords: molecular genetics; molecular breeding; genome editing (CRISPR); omics technologies; stress resilience; trait discovery; genomic selection; sustainable agriculture; crop improvement; artificial intelligence in breeding

(This special issue belongs to the Section Molecular Genetics)

Ocular Surface and Corneal Diseases: From Cellular and Molecular Biology to Therapeutic Strategies

edited by

Anat Galor

and Pragnya Rao Donthineni

submission deadline 31 Dec 2025 | Viewed by 21 | Submission Open

Keywords: dry eye disease; dry eye; aqueous tear deficiency; evaporative deficiency; ocular surface inflammation; tear osmolarity; epidemiology; limbal stem cell deficiency; neuropathic ocular pain; neurotrophic keratitis

The Role of DNA Methylation, Histone Modifications and MicroRNA in Cancer

edited by

Joanna Szczepanek

submission deadline 31 Dec 2025 | Viewed by 21 | Submission Open

Keywords: epigenetic regulation; DNA methylation; histone modifications; microRNA; cancer progression; therapeutic resistance; tumor suppressor genes; oncogenic reprogramming; personalized cancer therapy; epigenetic therapy

Molecular Mechanisms Underlying Liver Diseases: 2nd Edition

edited by

Wei Zhong

submission deadline 31 Dec 2025 | Viewed by 14 | Submission Open

Keywords: pathogenesis of liver diseases; molecular mechanisms; organelle damages; genetic determinants; organ– organ interactions; biomarkers; in vivo models of liver diseases; therapeutic insights

(This special issue belongs to the Section Cellular Biochemistry)

Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon: 2nd Edition

edited by

Eun-Woo Lee

and Jiho Yoo

submission deadline 31 Dec 2025 | Viewed by 3 | Submission Open

Keywords: biomolecules; cancer; angiogenesis; autophagy; GPCRs; translational applications; target identification; proximity-labeling; molecular docking; molecular probe; molecular pharmacology

(This special issue belongs to the Section Cellular Biochemistry)

Updates on Mitochondria and Cancer

edited by

Antonella Cormio

and

Clara Musicco

submission deadline 15 Jan 2026 | Viewed by 68 | Submission Open

Keywords: mitochondrial dysfunction in cancer; mitochondrial metabolomics; mitochondria and cancer therapy; mitochondria and cancer drug resistance; prognostic/predictive mitochondrial markers in cancer tissues and body fluids

(This special issue belongs to the Section Biological Factors)

Inflammation and Immunity in Lung Disease

edited by

Xuexian Yang

submission deadline 15 Jan 2026 | Viewed by 17 | Submission Open

Keywords: lung; infection; inflammation; host defense; cytokine release syndrome; genetic deficiency

Natural Products and Their Derivatives with Antiviral Activity

edited by

Zhijun Zhang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 588 | Submission Open

Keywords: natural products; synthetic antivirals; antiviral drugs; antiviral strategies; influenza; HBV; HIV; RSV; COVID-19; SARS-CoV-2

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Inflammation Biology in Orthodontic Tooth Movement

edited by

Masaru Yamaguchi

submission deadline 31 Jan 2026 | Viewed by 243 | Submission Open

Keywords: orthodontic tooth movement; inflammation; cytokine; root resorption; accelerated orthodontic tooth movement; relapse

(This special issue belongs to the Section Biological Factors)

New Insights into Mesothelial Cell

edited by Francesca Bodega and Cristina Porta

submission deadline 31 Jan 2026 | Viewed by 66 | Submission Open

Keywords: mesothelial cells; serous cavities; lubricating fluids; epithelial– mesenchymal transition; fibrosis; tissue repair; mesothelioma; tumor microenvironment; immune response

(This special issue belongs to the Section Molecular Biology)

Mechanisms in Stress-Related Disorders, Anxiety and Fear

edited by Veronica Begni

submission deadline 31 Jan 2026 | Viewed by 43 | Submission Open

Keywords: stress-related disorders; anxiety; fear; genetic and environmental interactions; behavioral neuroscience; biological pathways; biomarkers; therapeutic interventions

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Traumatic Brain Injury

edited by Xiang Gao

submission deadline 22 Feb 2026 | Viewed by 21 | Submission Open

Keywords: traumatic brain injury; cell death; neural degeneration/regeneration; genetic modification; neuroprotection

Molecular and Cellular Mechanisms in Anti-Thrombosis

edited by

Joen-Rong Sheu

and

Thanasekaran Jayakumar

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1252 | Submission Open

Keywords: platelet activation and thrombosis; neuroprotection; antithrombotic mechanisms

(This special issue belongs to the Section Molecular Medicine)

Protein Arginine Methylation: Functions, Mechanisms, and Therapeutic Implications

edited by Yanzhong Yang

submission deadline 31 Mar 2026 | Viewed by 16 | Submission Open

Keywords: protein arginine methyltransferases; transcription; RNA splicing; signaling transduction; DNA repair; cancer; development; small molecule inhibitor

Molecular Basis and Translational Research in Metabolic Myopathies: A Themed Issue in Honor of Professor Corrado Angelini, 2nd Edition

edited by

Marija Meznaric

Daniela Tavian

and

Sara Missaglia

submission deadline 31 May 2026 | Viewed by 32 | Submission Open

Keywords: metabolic myopathies; lipid metabolism; glycogen metabolism; genetic diseases; treatments; lipid storage myopathies; glycogen storage myopathies; lysosomal storage myopathies

(This special issue belongs to the Section Molecular Biology)

Bench and Bedside: Molecular Insights and Neuroprotective Strategies for Stroke

edited by

Yuchuan Ding

submission deadline 31 May 2026 | Viewed by 2 | Submission Open

Keywords: neuroprotection; neurorehabilitation; conditioning medicine; ischemia and reperfusion injury; cerebral hemor-rhages; stress; vascular diseases

(This special issue belongs to the Section Molecular Medicine)

Advances in Pharmacognosy and Phytochemistry: From Molecular to Pre-Clinical Insights

edited by

Hilal Zaid

Zipora Tietel

and

Akhilesh K. Tamrakar

submission deadline 30 Jun 2026 | Viewed by 626 | Submission Open

Keywords: metabolomics; drug discovery; phytopharmacology; medicinal plants

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Molecular Pathology, Diagnostics, and Therapeutics of Lung Disease

edited by