Matrix Metalloproteinases: Mechanisms, Functions and Therapeutic Potential
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 31 May 2025 | Viewed by 2511
Special Issue Editors
Interests: cancer; matrix metalloproteinases (MMPs); yeast surface display; Protein Engineering; Proteases Inhibitors; targeted therapy; extracellular matrix
Interests: flow cytometry; real-time PCR; immunofluorescence techniques; Western Blot; apoptosis; cell differentiation; analytical chemistry; cell culture; biochemistry
Interests: biochemistry; biophysics; cancer biology; drug discovery; human serum albumin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play pivotal roles in extracellular matrix (ECM) remodeling and degradation. They are involved in a wide range of physiological processes, including tissue repair, embryogenesis, and angiogenesis. However, dysregulation of MMP activity has been implicated in various pathological conditions, such as cancer, cardiovascular diseases, and inflammatory disorders. The multifaceted roles of MMPs in health and disease have made them a focal point of biomedical research.
This Special Issue aims to explore the latest advancements in MMP research, encompassing their molecular mechanisms, regulatory pathways, and functional implications. We invite original research articles, reviews, and perspectives that provide insights into the structural biology of MMPs, their role in tissue homeostasis and disease progression, and the development of MMP inhibitors as therapeutic agents. Through this compilation, we seek to enhance our understanding of MMPs and foster the development of novel therapeutic strategies targeting these versatile enzymes.
Dr. Alireza Shoari
Dr. Joshua W. Ogony
Dr. Gokara Mahesh
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- matrix metalloproteinases
- endopeptidases
- MMP inhibitor
- tissue homeostasis
- disease progression
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