Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Antioxidant Effects of Bioactive Compounds submission deadline 5 Feb 2026 | 1 articles | Viewed by 3154 | Submission Open
Keywords: bioactive compounds; polyphenols; oxidative stress; chronic diseases; nutraceuticals
Advances in Cold Therapies: Novel Physical Approaches for Musculoskeletal Repair–Molecular Insights
edited by Fackson Mwale
submission deadline 6 Feb 2026 | Viewed by 223 | Submission Open
Keywords: cold therapy; cryotherapy; cryoablation; musculoskeletal repair; inflammation modulation; regenerative medicine; extracellular matrix; cold shock proteins; tissue regeneration; physical therapy
CD5 and CD6 Immunobiology: Multitask Immunomodulatory Molecules in Infection, Cancer and Autoimmunity
edited by Lozano Francisco and María Velasco-de Andrés
submission deadline 13 Feb 2026 | Viewed by 161 | Submission Open
Keywords: CD5; CD6; T cells; B1a cells; NK cells; immunomodulation; infection; cancer; autoimmunity; immunotherapy
(This special issue belongs to the Section Biological Factors)
Molecular Insights into the Mechanism of Antipsychotic Drugs
edited by Serdar Dursun and
submission deadline 15 Feb 2026 | 2 articles | Viewed by 10257 | Submission Open
Keywords: psychotropic medications; antipsychotic drugs; schizophrenia; molecular mechanisms
(This special issue belongs to the Section Molecular Biology)
Advances in Antiviral Drug Development
edited by Angel S. Galabov
submission deadline 15 Feb 2026 | Viewed by 206 | Submission Open
Keywords: viral inhibitors; mechanism of action; antiviral tests
(This special issue belongs to the Section Molecular Medicine)
Advances in Various Roles of High-Density Lipoproteins
edited by
submission deadline 15 Feb 2026 | Viewed by 158 | Submission Open
Keywords: atherosclerosis; high-density lipoprotein (HDL); HDL functions; apolipoproteins; lipid and glucose metabolism
(This special issue belongs to the Section Lipids)
Recent Advances in Immunotherapy for Mesothelioma
edited by Licun Wu
submission deadline 15 Feb 2026 | Viewed by 128 | Submission Open
Keywords: mesothelioma; immunotherapy; tumor microenvironment; biomarkers; tumor heterogeneity
(This special issue belongs to the Section Molecular Medicine)
Evolutionary Genomics of Bacterial Endosymbionts: From Mutualism to Parasitism
edited by
submission deadline 20 Feb 2026 | Viewed by 218 | Submission Open
Keywords: host– symbiont coevolution; metabolic pathways; horizontal DNA transfer; phylogenetics
Molecular Mechanisms of Traumatic Brain Injury
edited by Xiang Gao
submission deadline 22 Feb 2026 | Viewed by 231 | Submission Open
Keywords: traumatic brain injury; cell death; neural degeneration/regeneration; genetic modification; neuroprotection
Molecular Advances in Wound Healing and Skin Regeneration
edited by and Muhammad Shafiq
submission deadline 28 Feb 2026 | 2 articles | Viewed by 32052 | Submission Open
Keywords: artificial dressings; electrospun fiber-based wound dressings; artificial skin equivalents; wound healing; instructive biomaterials for in situ skin repair; microneedles for skin therapy; drug delivery systems for wound healing; cell-free approaches for skin repair; stem cell therapy for wound healing; scarless skin repair
(This special issue belongs to the Section Biological Factors)
Design and Synthesis of Bioactive Compounds for Therapeutic Applications submission deadline 28 Feb 2026 | 12 articles | Viewed by 30773 | Submission Open
Keywords: drug design and discovery; synthesis of bioactive molecules; biological evaluations and applications; diagnostics; drug delivery
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Chronic Heart Failure: From Molecular Mechanisms to Therapies Strategies submission deadline 28 Feb 2026 | 9 articles | Viewed by 20841 | Submission Open
Keywords: chronic heart failure; pathophysiology; comorbidities; new therapies; molecular pathways
(This special issue belongs to the Section Molecular Medicine)
Cannabinoids in Neurobehavioral Modulation submission deadline 28 Feb 2026 | 4 articles | Viewed by 19418 | Submission Open
Keywords: cannabinoids; neurobehavior; brain diseases; therapeutic; translational
(This special issue belongs to the Section Molecular Biology)
Inflammatory Mechanisms and Molecular Targets in Neurological Disorders: Effects of Neuroprotective Drugs submission deadline 28 Feb 2026 | 4 articles | Viewed by 14108 | Submission Open
Keywords: neuroinflammation; neurological disorders; molecular targets; therapeutic strategies; neuroimmunology
(This special issue belongs to the Section Molecular Medicine)
Cellular Quiescence and Dormancy
edited by
submission deadline 28 Feb 2026 | 7 articles | Viewed by 13873 | Submission Open
Keywords: quiescent cells; dormant cells; biostasis; diapause; spores; dauer larva
(This special issue belongs to the Section Molecular Genetics)
Immune Responses in Type 1 Diabetes
edited by and Sally C. Kent
submission deadline 28 Feb 2026 | 5 articles | Viewed by 13823 | Submission Open
Keywords: type 1 diabetes; insulitis; immune response
(This special issue belongs to the Section Molecular Biology)
Innovative Biomolecular Structure Analysis Techniques
edited by Tzanko I. Doukov
submission deadline 28 Feb 2026 | 6 articles | Viewed by 11905 | Submission Open
Keywords: macromolecular crystallography; room temperature crystallography; protein ensembles; NMR; MD simulations
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Novel Molecules for Cancer Treatment (3rd Edition) submission deadline 28 Feb 2026 | 5 articles | Viewed by 10755 | Submission Open
Keywords: cancer; small molecules; antibody-drug-conjugated; tyrosine kinase inhibitors; target therapy; monoclonal antibodies; immunotherapy; natural compounds
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Structural Biology of Protein
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 9087 | Submission Open
Keywords: structural characterization; protein structure– function paradigm; biophysical techniques; computational methods; conformational dynamics; drug discovery; protein– protein interactions
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Biomarkers and Molecular Basis of Psychiatry
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 8592 | Submission Open
Keywords: mental health; bipolar disorders; mood; anxiety; psychosis; schizophrenia; biomarkers
(This special issue belongs to the Section Biological Factors)
Molecular Signalling Pathways in Tumorigenesis and Tumor Suppression
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 7621 | Submission Open
Keywords: E2F; RB; p53; cancer; tumor suppression
(This special issue belongs to the Section Biological Factors)
Advancing Molecular Regulation in Brain Injury Research: Mechanisms, Diagnosis, and Rehabilitation
edited by Guanglin Zhang and
submission deadline 28 Feb 2026 | 4 articles | Viewed by 7181 | Submission Open
Keywords: brain injury; biomarkers; neurodegeneration; neuroplasticity; neuroimaging; microbial dysbiosis; gut– brain axis; cognitive rehabilitation
(This special issue belongs to the Section Molecular Biology)
Genetic and Genomic Biomarkers in Cancer Diagnosis, Prognosis, and Treatment Prediction
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 6697 | Submission Open
Keywords: laboratory genetics and genomics; genetic and genomic biomarkers; diagnostic; prognostic; predictive; companion diagnosis; targeted therapy; nucleic acid
(This special issue belongs to the Section Molecular Biomarkers)
New Insights into Forensic Molecular Genetics
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 6577 | Submission Open
Keywords: forensic; DNA; RNA; protein; mtDNA; epigenetics; microbiome
(This special issue belongs to the Section Molecular Genetics)
Heterocyclic Compounds as Novel Anti-Cancer Agents and Their Mechanisms of Action
edited by Chandra Mishra and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5234 | Submission Open
Keywords: heterocyclic compounds; anticancer; synthetic; natural
(This special issue belongs to the Section Molecular Medicine)
Glutamate and Glutamate Receptors in Health and Diseases, Second Edition submission deadline 28 Feb 2026 | 3 articles | Viewed by 4872 | Submission Open
Keywords: glutamate receptors; addiction; pain; learning and memory; anxiety; depression; autism; neurodegeneration
(This special issue belongs to the Section Molecular Biology)
Polyphosphate (PolyP) in Health and Disease
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 4137 | Submission Open
Keywords: polyphosphate; polyP; biomarker and therapeutic target
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Biomarkers in Metabolic Diseases, 2nd Edition submission deadline 28 Feb 2026 | 3 articles | Viewed by 3607 | Submission Open
Keywords: metabolic disorders; inborn errors of metabolism; surrogate biomarkers; biochemical markers; diagnostic markers; newborn screening; molecular analyses; metabolomics; disease progression; treatment efficacy
(This special issue belongs to the Section Molecular Biomarkers)
Molecular Mechanism and Detection of SARS-CoV-2
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3395 | Submission Open
Keywords: SARS-CoV-2 spike protein; ACE2 receptor; viral pathogenesis; host-viral protein interactions; molecular diagnostics; RNA virus replication; immune response; viral structural proteins; pathobiology; RT-PCR detection
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms of Endometriosis: 2nd Edition
edited by , Alessandra Andrisani and Chiara Sabbadin
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3354 | Submission Open
Keywords: endocrine disfunction in endometriosis; glycosylphosphatidylinositols (GPIs) and GPI-anchored proteins; oxidative stress markers (glutathione; carbonic anhydrase; etc.); endometriosis and deep endometriosis; endometriosis-related immune system
(This special issue belongs to the Section Molecular Biology)
Hyaluronic Acid and Proteoglycans: Basic and Biomedical Applications: 2nd Edition
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 3354 | Submission Open
Keywords: hyaluronic acid; proteoglycans; GAGs; extracellular matrix; hyaluronic acid and proteoglycans in disease; cancer; inflammation; angiogenesis; vascular homeostasis and damage; arthritis and arthrosis; glycobiology
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Tumor Genomics and Liquid Biopsy in Cancer Biology
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3138 | Submission Open
Keywords: circulating tumor DNA (ctDNA); circulating tumor cells (CTCs); exosomes and extracellular vesicles; circulating free RNAs and microRNAs; tumor heterogeneity; mechanisms of metastasis; tumor clonal evolution; drug resistance; tumor microenvironment; multi-omics integration
(This special issue belongs to the Section Molecular Biology)
Molecular Biology of Age-Related Macular Degeneration: From Pathogenesis to Therapeutic Strategies
edited by , Pier Luigi Grenga and Chiara Ciancimino
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2968 | Submission Open
Keywords: age-related macular degeneration; vascular endothelial growth factor (VEGF); inflammation; neurodegeneration; single-nucleotide polymorphisms (SNP)
(This special issue belongs to the Section Molecular Biology)
Molecular and Cellular Mechanisms of Aortic Diseases
edited by Maria Giovanna Scioli
submission deadline 28 Feb 2026 | 4 articles | Viewed by 2896 | Submission Open
Keywords: aortic aneurysms; acute aortic syndromes; aortic dissection; intramural haematoma; penetrating atherosclerotic ulcer; traumatic aortic injury; pseudoaneurysm; aortic rupture; atherosclerotic; inflammatory affections; Marfan syndrome; congenital abnormalities; aortic diseases
(This special issue belongs to the Section Molecular Biology)
Single-Molecule Protein Electronics
edited by and Bintian Zhang
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2693 | Submission Open
Keywords: protein electronics; molecular electronics; single-molecule conductance; protein detection; protein sensing; label-free detection; conductance gating in proteins; electron transport mechanisms in proteins; coherence and dephasing in proteins; role of water in protein conductance; extended electronic states in proteins; hopping conductance in proteins; long-range hopping in proteins; electrode– protein interfaces; charge injection barriers at protein– electrode interfaces; proteins as electronic devices; protein assemblies as electronic devices; DNA electronics; electron transport in DNA; DNA– electrode interfaces; charge injection at a DNA– electrode interface; barrier to charge injection at a DNA– electrode interface
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Exploring Thermophilic Enzymes: From Structural Foundations to Functional Enhancement
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 2178 | Submission Open
Keywords: thermostable enzymes; structural biology; protein engineering; functional enhancement; industrial applications; thermal stability mechanisms; biotechnology
(This special issue belongs to the Section Enzymology)
Recent Advances in Retroviruses and Endogenous Retroviruses (ERVs) in Mammalian Placenta and Beyond 2025 submission deadline 28 Feb 2026 | 2 articles | Viewed by 1922 | Submission Open
Keywords: retroviruses; ERVs (endogenous retroviruses); placental diversity; organ development (stem cells); immunoregulation
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
The Planarian Model in Pharmacology, Toxicology, and Neuroscience
edited by Oné R. Pagán
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1522 | Submission Open
Keywords: planarians; pharmacology; toxicology; neuroscience; neurotransmission; regeneration
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms in Cardiorenal Syndrome
edited by , María Carmen Ruiz Fuentes and Maria José Espigares Huete
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1429 | Submission Open
Keywords: cardiorenal syndrome; renal failure; heart; kidney; heart failure
(This special issue belongs to the Section Molecular Biology)
Biomarkers and Therapeutic Approaches in Melanoma: New Omics-Strategies submission deadline 28 Feb 2026 | 1 articles | Viewed by 1374 | Submission Open
Keywords: melanoma; biomarkers; omics; precision oncology; drug resistance
(This special issue belongs to the Section Molecular Biomarkers)
Novel Insights and Applications of Pluripotent Stem Cells
edited by and Ben Rollo
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1274 | Submission Open
Keywords: pluripotent stem cells; pluripotency; differentiation; stem cell transplant; regenerative medicine; disease modeling; organoids; therapeutic screening; cell therapies; drug discovery
(This special issue belongs to the Section Cellular Biochemistry)
Oxidative Stress and Ferroptosis in Health and Disease
edited by Udayakumar Karunakaran and Suma Elumalai
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1154 | Submission Open
Keywords: reactive oxygen species; antioxidants; glutathione; iron; H2S signaling; diabetes; metabolic disease; mitochondrial biology; ferroptosis; cell death; inflammation; aging; neurodegenerative diseases
(This special issue belongs to the Section Chemical Biology)
Insights into Mitochondria in Psychiatric Disorders
edited by Ji Geng
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1150 | Submission Open
Keywords: mitochondria; depression; schizophrenia; autism; neurodevelopmental disorders
(This special issue belongs to the Section Cellular Biochemistry)
Studies of Protein Dynamics, Interactions, and Concentration by Fluorescence Fluctuation Correlation Spectroscopy (FFCS)
edited by Jieqiong Lou and Elvis Pandžić
submission deadline 28 Feb 2026 | 1 articles | Viewed by 899 | Submission Open
Keywords: fluorescence fluctuation correlation spectroscopy (FFCS); fluorescence correlation spectroscopy (FCS); image correlation spectroscopy (ICS); pair correlation function (pCF) analysis; line-scan correlation; protein dynamics; molecular diffusion; molecular flow; confinement dynamics; protein– protein interactions; membrane organization; intracellular transport; molecular crowding; spatiotemporal fluctuations; concentration heterogeneity; live-cell imaging; single-molecule analysis; quantitative fluorescence microscopy; biophysics; super-resolution fluctuation analysis
Molecular Mechanisms and Drug Research in Alzheimer’s Disease
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 887 | Submission Open
Keywords: Alzheimer's disease; molecular mechanisms; drug discovery; Aβ amyloid; tau protein; neuroinflammation; oxidative stress; metal homeostasis; blood– brain barrier; dysbiosis
(This special issue belongs to the Section Molecular Medicine)
Functional Analysis of Genes Related to DNA Damage
edited by Ryan P. Barnes and Amy M. Whitaker
submission deadline 28 Feb 2026 | 1 articles | Viewed by 722 | Submission Open
Keywords: DNA damage; DNA repair; genome stability; DNA replication stress
(This special issue belongs to the Section Molecular Biology)
Exploring Novel Molecular Pathways and Emerging Treatments for Neuromuscular Disorders submission deadline 28 Feb 2026 | 1 articles | Viewed by 427 | Submission Open
Keywords: gene therapy; repurposing; therapeutic oligonucleotides; personalized medicine; biomarkers
(This special issue belongs to the Section Molecular Medicine)
Virus-Host Protein Interactions
edited by
submission deadline 28 Feb 2026 | Viewed by 351 | Submission Open
Keywords: protein– protein interactions; antiviral drug discovery; protein target inhibitors
Novel Drug Targets and RNA Epigenetics in Cancer Therapy
edited by Manjeet K. Rao
submission deadline 28 Feb 2026 | Viewed by 327 | Submission Open
Keywords: RNA modifications; cancer epigenetics; novel drug targets; RNA therapeutics; tumorigenesis
(This special issue belongs to the Section Molecular Biology)
Cellular Signaling and Cardiovascular Diseases: From NF-κB to Golgi Dynamics
edited by
submission deadline 28 Feb 2026 | Viewed by 281 | Submission Open
Keywords: cardiovascular diseases; NF-κ B signaling; vascular cells; epigenetic regulation; vascular inflammation; intercellular crosstalk; Golgi dynamics  
(This special issue belongs to the Section Cellular Biochemistry)
Back to TopTop