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Special Issue "Cell Biology and Biomedical Application of Galectins"
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 30 September 2023 | Viewed by 1879
Special Issue Editor
Interests: galectins; O-GlcNAc; cellular differentiation; glycobiology; cell aggregation; neutrophils
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Galectins are a family of soluble b-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions, both outside and inside the cell. Galectins play a role in many fundamental cellular processes, such as cell growth, differentiation, self-renewal, apoptosis, autophagy, phagocytosis, and cellular interactions. Changes in the expression of galectins are linked to diseases such as cancer, heart disease, and fibrosis, among others, which suggests that they are potential candidates for biomedical applications. However, current success in these directions is limited, primarily due to the complex network of interacting galectins in cells and their different modes of action. The functions of galectins depend on their localization in specific cellular compartments and organelles (cytosol, lipid droplets, cytoskeleton, mitochondria, nucleus, lysosomes, and plasma membrane) and related intracellular trafficking and secretion, which occurs through non-classical pathways. An integrated vision of galectin cell biology is still needed, and advanced studies of galectin trafficking, post-translational modifications, the transcriptional regulation of galectin gene expression, and galectin-mediated transmembrane signaling are highly warranted. This Special Issue covers recent progress in the fields of the cell biology of galectins and the biomedical aspects of these molecules as biomarkers and clinical targets in the context of human diseases.
Dr. Alexander Timoshenko
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cell differentiation
- stem cells
- cell adhesion
- post-translational modifications
- transmembrane signaling
- protein trafficking
- heart diseases
- targeted therapeutics
- galectin inhibitors
Related Special Issue
- Cell Biology of Galectins in Biomolecules (11 articles)
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Galectins — Evidence for GlycoLipid-Lectin Endocytosis and Lattices
Authors: Ludger JOHANNES; Massiullah Shafaq-Zadah；Estelle Dransart
Affiliation: Institut Curie – Paris