Cellular and Molecular Basis of Parasite Infection
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 251
Special Issue Editors
Interests: parasitic diseases; communicable diseases; infectious disease prevention and control
Interests: parasitic diseases; public health; communicable diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Parasite infections are complex biological processes that involve intricate interactions between the parasite and the host at both cellular and molecular levels. Understanding these interactions is crucial for developing effective treatments and preventive measures. At the cellular level, parasites often invade host cells, utilizing the host's cellular machinery to replicate and evade the immune system. For instance, Plasmodium, the parasite responsible for malaria, invades red blood cells and modifies their surface proteins to avoid detection.
On a molecular level, parasites secrete various molecules that manipulate host cell functions. These molecules can interfere with signaling pathways, immune responses, and cellular metabolism. For example, the Trypanosoma brucei parasite, which causes African sleeping sickness, uses a process called antigenic variation to change its surface glycoproteins, helping it evade the host's immune system.
Research in this field focuses on identifying the specific cellular and molecular mechanisms parasites use to infect hosts and how hosts respond to these infections. This knowledge is essential for developing new drugs, vaccines, and diagnostic tools to combat parasitic diseases.
Dr. Adekunle Sanyaolu
Dr. Ricardo Izurieta
Guest Editors
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Keywords
- parasite infection
- host–parasite interaction
- cellular invasion
- molecular mechanisms
- immune evasion
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