Microbiome–Gut–Brain Axis in Neurodevelopmental Disorders
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 April 2026
Special Issue Editors
Interests: Child and Adolescent Psychiatry
Special Issue Information
Dear Colleagues,
The microbiome–gut–brain (MGB) axis is a complex and highly sophisticated system of bidirectional communication between the intestinal milieu and the central nervous system which regulates the maturation and the function of several body physiological systems, thus playing a crucial role in human homeostasis. There are evolving research data suggesting that early microbial colonization runs in parallel with neurogenetic and synaptogenetic processes within the brain which underserve its capacity to get organized, conceptualize, learn, adjust, relate and self-reflect. Disturbances of the MGB axis lie at the heart of aberrant neurodevelopment including autism, schizophrenia, attention deficit and hyperactivity disorder, and other neurodevelopmental conditions. In this respect, research on the molecular and physiological pathways which mediate microbiota–gut–brain cross-talk and its clinical and behavioral correlates may disentangle and further expand current knowledge on the etiology of neurodevelopmental disorders. This Special Issue entitled “Microbiome–Gut–Brain Axis in Neurodevelopmental Disorders” welcomes original and review articles focusing on the contribution of the MGB axis to the pathophysiology and clinical course of neurodevelopmental disorders, particularly emphasizing the underlying molecular, neurochemical, and cellular events and the potential role of microbiota-related processes in the diagnostic assessment and management of these conditions.
Dr. Katerina Karaivazoglou
Dr. Konstantinos Kotsis
Guest Editors
Manuscript Submission Information
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Keywords
- microbiome–gut–brain axis
- neurodevelopmental disorders
- autism
- schizophrenia
- intestinal dysbiosis
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