Antioxidant Properties and Applications of Food By-Products—2nd Edition

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Extraction and Industrial Applications of Antioxidants".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 506

Special Issue Editor

School of Food Science, South China Agricultural University, Guangzhou 510642, China
Interests: polyphenols; polysaccharides; dietary fiber; bioactivity; interaction between food components; starch digestibility; gut microbiota; functional foods; utilization of agricultural by-products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Following the positive reception and valuable contributions to our first Special Issue, we are delighted to launch its sequel: “Antioxidant Properties and Applications of Food By-Products—2nd Edition”.

The journey towards sustainable resource management continues. Food manufacturing still generates substantial by-products, often misclassified as ‘waste’, leading to significant resource loss and environmental challenges. Yet these very by-products are a treasure trove of bioactive compounds—from natural antioxidants like polyphenols and carotenoids to essential macronutrients such as dietary fibers and proteins. The pioneering research featured in our first edition underscored the immense potential of these components in functional foods, pharmaceuticals, and cosmetics, setting the stage for further innovation.

This second edition aims to deepen the exploration into advanced extraction and valorization strategies. We seek to compile cutting-edge research on the recovery, processing, and functionality of these valuable substances, with a special emphasis on their antioxidant capabilities and other bioactivities. We welcome contributions that address novel processing technologies, comprehensive characterization methods, and mechanisms of action that pave the way for high-value industrial applications.

By bridging critical knowledge gaps and fostering interdisciplinary dialogue, this Special Issue will further establish food by-products as essential contributors to a circular economy. We invite original research and review articles that push the boundaries of science and technology in this dynamic field, ultimately promoting global environmental and food sustainability.

We look forward to receiving your impactful contributions.

Dr. Kai Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food by-products 
  • nutrients 
  • extracts 
  • bioactive compounds 
  • antioxidant activity 
  • physiochemical properties 
  • functional food
  • value-added application

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Published Papers (1 paper)

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Review

24 pages, 2286 KB  
Review
Antioxidant Protein Hydrolysates and Peptides from Catfish: Enzymatic Production, In Vitro Bioactivity, and Translational Gaps for Functional Foods
by Fai-Chu Wong, Ai-Lin Ooi, Wen-Jie Ng, Fazilah Abd Manan and Tsun-Thai Chai
Antioxidants 2026, 15(5), 631; https://doi.org/10.3390/antiox15050631 - 15 May 2026
Viewed by 203
Abstract
Over the past decade, an increasing demand for natural antioxidants has driven research into antioxidant peptides and protein hydrolysates from fish and their processing by-products. Catfishes, especially species like Pangasius and Clarias, generate large amounts of protein-rich by-products, which represent a valuable [...] Read more.
Over the past decade, an increasing demand for natural antioxidants has driven research into antioxidant peptides and protein hydrolysates from fish and their processing by-products. Catfishes, especially species like Pangasius and Clarias, generate large amounts of protein-rich by-products, which represent a valuable bioresource for valorization. This review discusses advances from the past decade in the production, characterization, and antioxidant capacity of protein hydrolysates and peptides that have been discovered from catfish muscle and by-products. This review emphasizes enzymatic hydrolysis strategies, using Alcalase and other commercial and by-product-derived proteases. Potent antioxidant fractions, particularly those with low molecular weight (<3 kDa) and rich in hydrophobic/aromatic amino acids, have been obtained from the hydrolysates. Mechanisms of antioxidant action, which include hydrogen atom transfer and electron transfer, are discussed in this review, along with the efficacy of catfish-derived antioxidant peptides and protein hydrolysates as demonstrated in chemical and in vivo models. Applications in food systems, such as emulsion-type sausages, have shown potential for shelf-life extension. Nevertheless, knowledge gaps remain, which include an over-dependence on in vitro assays, limited identification of antioxidant peptide sequences, and insufficient data on sensory properties, intestinal permeability, bioavailability, and stability under food processing conditions. Future work should prioritize proteomic characterization, cellular validation, flavor-masking strategies, and scalable production protocols to accelerate the application of catfish protein hydrolysates as viable natural antioxidants for the functional food industry. Full article
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