Antioxidants in Health and Disease: Environmental Challenges, Redox Homeostasis, and Adaptive Responses
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 991
Editor
Interests: human biomonitoring; metals/metalloids; pesticides; oxidative stress; antioxidants; combined exposure and interactions; health effects; metabolomics; biomarkers; analytical chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antioxidants are key regulators of human health, maintaining redox balance, supporting adaptive stress responses, modulating inflammation, and preserving immune function. Endogenous and exogenous antioxidants work together to mitigate molecular damage and enhance cellular resilience to diverse stressors, aiding disease prevention and management. Environmental challenges, including chemical exposure, climate-related extremes, and lifestyle factors, can disrupt redox homeostasis, alter the microbiome, and reduce nutrient quality and availability, thereby increasing susceptibility to disease.
This Special Issue aims to explore antioxidants’ role in disease prevention and examine the complex interplay between environmental challenges, antioxidant defense systems, and adaptive redox responses at molecular, cellular, and systemic levels. We are seeking submissions of original research and review articles addressing how antioxidant pathways are activated, modulated, or disrupted by environmental exposures or climate-related stress; how exogenous antioxidants contribute to protection and resilience; and how these processes influence human health, disease progression, and therapeutic outcomes. Contributions which integrate mechanistic, clinical, nutritional, epidemiological, or translational perspectives are of particular interest.
Dr. Alica Pizent
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidants
- redox biology
- oxidative stress
- environmental exposures
- adaptive responses
- resilience
- Nrf2 pathway
- endogenous antioxidants
- exogenous antioxidants
- cellular homeostasis
- environmental toxicology
- climate-related stress
- human health
- chronic disease
- prevention
- therapeutic strategies
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