Antibiotic-Associated Dysbiosis and Management

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 20 February 2025 | Viewed by 2011

Special Issue Editor


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Guest Editor
Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Biomedical Research Institute, Pusan National University, Yangsan 50612, Republic of Korea
Interests: dysbiosis; antibiotics; immunity; microbiota; intervention
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Special Issue Information

Dear Colleagues,

We are currently seeking high-quality research papers, reviews, and short communications for an upcoming Special Issue entitled "Antibiotic-Associated Dysbiosis and Management." Antibiotic-associated dysbiosis refers to the imbalance of the mucosal microbiota caused by antibiotic treatments, which can lead to various adverse health outcomes. The aim of this Special Issue is to explore the complex interactions between antibiotics, dysbiosis, and immunity, as well as the application of innovative interventions to manage dysbiosis and restore the health of the microbiota. Topics of interest include, but are not limited to, the following:

  • Dysbiosis: Investigations into the disruption of the microbial balance in the gut and other mucosal surfaces due to antibiotic use.
  • Mucosal or systemic Immunity: Research exploring how dysbiosis affects mucosal immune responses and the overall immune system.
  • Microbiota: Insights into the composition and function of microbiota communities in health and disease, particularly in the context of antibiotic exposure.
  • Management or Intervention: Innovative strategies and interventions aimed at preventing or managing antibiotic-associated dysbiosis and restoring microbial balance.

Prof. Dr. Yuseok Moon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dysbiosis
  • antibiotics
  • immunity
  • microbiota
  • intervention

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Published Papers (1 paper)

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Review

14 pages, 680 KiB  
Review
Gut Microbiota and New Microbiome-Targeted Drugs for Clostridioides difficile Infections
by Ahran Lee, Jung Sik Yoo and Eun-Jeong Yoon
Antibiotics 2024, 13(10), 995; https://doi.org/10.3390/antibiotics13100995 - 20 Oct 2024
Viewed by 1759
Abstract
Clostridioides difficile is a major causative pathogen for antibiotic-associated diarrhea and C. difficile infections (CDIs) may lead to life-threatening diseases in clinical settings. Most of the risk factors for the incidence of CDIs, i.e., antibiotic use, treatment by proton pump inhibitors, old age, [...] Read more.
Clostridioides difficile is a major causative pathogen for antibiotic-associated diarrhea and C. difficile infections (CDIs) may lead to life-threatening diseases in clinical settings. Most of the risk factors for the incidence of CDIs, i.e., antibiotic use, treatment by proton pump inhibitors, old age, and hospitalization, are associated with dysbiosis of gut microbiota and associated metabolites and, consequently, treatment options for CDIs include normalizing the composition of the intestinal microbiome. In this review, with an introduction to the CDI and its global epidemiology, CDI-associated traits of the gut microbiome and its metabolites were reviewed, and microbiome-targeting treatment options were introduced, which was approved recently as a new drug by the United States Food and Drug Administration (U.S. FDA), rather than a medical practice. Full article
(This article belongs to the Special Issue Antibiotic-Associated Dysbiosis and Management)
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