Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanism and Evolution of Antibiotic Resistance".
Deadline for manuscript submissions: 15 September 2025 | Viewed by 117
Special Issue Editors
2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
Interests: antimicrobial resistance (AMR); microbial genomics, genomic epidemiology of carbapenem-resistant enterobacterales, and hypervirulent Klebsiella pneumoniae, plasmids harboring bla CARBAPENEMASES; high-risk clones
2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
Interests: antimicrobial resistance (AMR); epidemiology of carbapenem-resistant enterobacterales; detection of carbapenemases-producing critical pathogens; mobile genetic elements.
Special Issue Information
Dear Colleagues,
Antimicrobial resistance (AMR) constitutes a global concern and is one of the main threats to public health in the 21st century. The massive, often abusive, use of antibiotics in human and veterinary medicine and food production threatens their future usefulness. This has led us towards a post-antibiotic era, in which common infections could be fatal again. Gram-negative bacteria resistant to last-resort antibiotics, such as Acinetobacter baumannii, and various pathogens in the Enterobacterales order, are considered to be a critical priority by the World Health Organization. They are frequently involved in severe infections/diseases, cause hospital outbreaks, and can spread in clinical settings. They have developed high-level resistance to carbapenems but are often resistant to other first-line antibiotics such as clinical β-lactamase inhibitors and fluoroquinolones, becoming difficult-to-treat pathogens. The transfer of resistance genes among them has been decisive for the high levels of resistance they have reached. Additionally, clonal expansion and the presence of high-risk clones have been recognized among these pathogens. The surveillance of these resistant pathogens is essential for providing early warnings about emerging issues, identifying new resistance markers, and adapting resistance mechanisms’ detection methods and antibiotic use to minimize therapeutic failures. This Special Issue aims to provide the latest research on the prevalence, resistance mechanisms, and control strategies of carbapenem-resistant pathogens in clinical settings. Through the analysis of critical pathogens, we aim to deepen our understanding of the factors driving resistance and to inspire the development of more effective solutions.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Surveillance of carbapenem-resistant Enterobacterales and A. baumanii.
- Characterization of plasmids harboring carbapenemases-coding genes.
- Detection and prevalence of carbapenem-resistant mechanisms.
- Rapid identification of carbapenem-resistant pathogens.
Dr. Daniela Cejas
Dr. Marcela Radice
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antibiotic resistance
- epidemiology
- carbapenemases
- carbapenem resistance
- enterobacterales
- acinetobacter baumannii
- resistance plasmids
- surveillance
- genomics
- high-risk clones
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