Antimicrobial Applications of Green Nanotechnology in Biomedicine and the Environment

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 2880

Special Issue Editors


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Faculty of Exact, Physical and Natural Sciences, National University of Córdoba, National Scientific and Technical Research Council (CONICET), Av. Vélez Sarsfield 299, Córdoba X5000JJC, Argentina
Interests: nanomaterial synthesis; nanomaterial characterization; antimicrobial nanomaterials; antimicrobial mechanisms; anti-biofilm strategies; drug delivery system; new antimicrobial drugs; drug resistance; emerging antimicrobial strategies; antibiotic-resistant pathogens; synergistic effects; biological safety; nanotoxicity; clinical studies; preclinical models; environmental and sustainable applications
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Guest Editor
Instituto de Investigaciones Fármaco Bioquímicas, Universidad Mayor de San Andrés, La Paz, Bolivia
Interests: molecular biochemistry; microbial biotechnology; fermentation; bioreactors; biotechnology; industrial biotechnology; environmental biotechnology

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Guest Editor
1. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología Del Comahue (CITAAC), Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Universidad Nacional Del Comahue, Buenos Aires 1400, Neuquén 8300, Argentina
2. Departamento de Ciencias Del Ambiente, Facultad de Ciencias Del Ambiente y la Salud, Universidad Nacional Del Comahue, Buenos Aires 1400, Neuquén 8300, Argentina
Interests: nanomaterial synthesis; antimicrobial mechanisms; drug delivery systems; nanotoxicity testing; in vitro and in vivo toxicity testing; nanomedicine; clinical studies; biological safety; environmental applications; environmental safety

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Guest Editor
Biopolymers & Sensors Lab., Macromolecules Institute, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Interests: natural resources; polymerization; nanocomposites; characterization; imaging; environmental recovery; nanomedicine; sensors; machine learning; data mining
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, nanomaterials exhibiting intrinsic antimicrobial activity, along with additive or synergistic effects with antibiotics and other antimicrobials, have been increasingly investigated and applied in several important fields, including biomedicine, agriculture, industry, and environmental sustainability. Furthermore, the "One Health" approach underscores the interdependence of human, animal, and plant health, highlighting the necessity for integrated strategies to combat antimicrobial resistance across ecosystems. The combination of Green Chemistry and Nanotechnology has facilitated the production of metallic nanoparticles via eco-friendly methods, utilizing fungi, bacteria, algae, and plant extracts for the bioreduction of metal salts and stabilization of the formed nanoparticles. These green nanoparticles are emerging as promising agents due to their unique antimicrobial properties and effectiveness against resistant strains. They can inhibit biofilm formation—a critical factor in chronic infections—and serve as drug delivery systems that enhance the efficacy of traditional antibiotics through synergistic effects. Their biocompatibility and low toxicity further position them as viable candidates for clinical applications.

This Special Issue aims to explore the latest advancements in green nanoparticles as antimicrobial agents, emphasizing their synthesis, characterization, and diverse applications in clinical and environmental contexts within the framework of the One Health approach. We encourage submissions that adopt a multidisciplinary perspective to address the challenges posed by antimicrobial resistance and promote sustainable therapeutic strategies. Additionally, we welcome contributions related to pharmaceutical nanotechnology, focusing on controlled drug delivery systems that enhance the biological activity of molecules while minimizing toxicity. We invite researchers to submit their work for consideration in this Special Issue, "Antimicrobial Applications of Green Nanotechnology in Biomedicine and the Environment".

Acknowledgments: Karina Cespo Andrada will be participating in this Special Issue as a "Special Collaborator". Special thanks are due for her contributions to this issue. 

Prof. Dr. María Gabriela Paraje
Dr. Maria Teresa A. Alvarez Aliaga
Dr. Natalia Lorena Guiñazú
Dr. Fernando Gomes de Souza Junior
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • green nanoparticles
  • eco-friendly synthesis
  • antimicrobial activity
  • anti-biofilm strategies
  • antimicrobial resistance
  • synergistic effects
  • drug delivery systems
  • nanotoxicity
  • sustainable nanotechnology
  • environmental applications
  • one health approach

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Published Papers (1 paper)

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Review

39 pages, 3056 KiB  
Review
Green Silver Nanoparticles: An Antibacterial Mechanism
by Ekaterina O. Mikhailova
Antibiotics 2025, 14(1), 5; https://doi.org/10.3390/antibiotics14010005 - 25 Dec 2024
Cited by 8 | Viewed by 2561
Abstract
Silver nanoparticles (AgNPs) are a promising tool in the fight against pathogenic microorganisms. “Green” nanoparticles are especially valuable due to their environmental friendliness and lower energy consumption during production, as well as their ability to minimize the number of toxic by-products. This review [...] Read more.
Silver nanoparticles (AgNPs) are a promising tool in the fight against pathogenic microorganisms. “Green” nanoparticles are especially valuable due to their environmental friendliness and lower energy consumption during production, as well as their ability to minimize the number of toxic by-products. This review focuses on the features of AgNP synthesis using living organisms (bacteria, fungi, plants) and the involvement of various biological compounds in this process. The mechanism of antibacterial activity is also discussed in detail with special attention given to anti-biofilm and anti-quorum sensing activities. The toxicity of silver nanoparticles is considered in light of their further biomedical applications. Full article
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