Ionic Liquids as Novel Antimicrobial Agents
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 345
Special Issue Editors
Interests: bacterial dormancy; ionic liquids; API-ILs; food safety; diagnostics; bacterial survival
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ionic liquids (ILs), which are organic salts with melting points below 100 °C, have found application in many areas of modern science. One property of ILs that quickly attracted researchers' attention was their antimicrobial, antifungal and virucidal activity, with initial studies reporting activity against MDR bacteria. The great advantage of ILs in this context is the strong correlation between their chemical structure and physicochemical properties such as bioavailability, biodegradability, solubility and antimicrobial activity. This tuneability of ILs promoted their entry into the pharmaceutical field as so-called third generation ILs. On the flipside, the possibility of synthesizing > 1018 new ILs by structural variation makes traditional screening with experimental studies unfeasible to identify new compounds with the desired properties. It is necessary to identify structure–activity relationships (SARs) to predict IL antimicrobial activity and to elucidate their mode of action at the cellular level. This Special Issue invites studies that not only report antimicrobial activity data of novel ILs but also contribute to a deeper understanding of the correlation between IL structure and their mechanism of action at the molecular level.
Dr. Patrick-Julian Mester
Dr. Tomasz Cłapa
Guest Editors
Manuscript Submission Information
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Keywords
- ionic liquids
- antimicrobials
- biocides
- bacteria
- fungi
- viruses
- structure–activity relationship
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