Challenges and Strategies for the Antibiotic Resistance Crisis

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1171

Special Issue Editors

CNRS, Aix-Marseille University, Centrale Marseille, iSm2, 13013 Marseille, France
Interests: mycotoxins; fungal metabolites; antimicrobial; anticancer; antinflammatory; antioxidant
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is compiled in cooperation with the 4th International Electronic Conference on Antibiotics, organized by Antibiotics from 21 to 23 May 2025 on the MDPI Sciforum platform (https://sciforum.net/event/ECA2025). We welcome submissions from the scientific community and stakeholders to present and discuss recent advances in antibiotic research.

The following areas were covered:

  • Antibiotics Stewardship and Antimicrobial Use in Healthcare Settings;
  • Antibiotics and One Health;
  • Epidemiology, Prevalence and Mechanisms of Antibiotics Resistance and Cross-Resistance;
  • Novel Antimicrobial Agents: Discovery, Design, Synthesis and Action;
  • Multidisciplinary Antimicrobial Strategies: Materials, Peptides, Bacteriophages and Repurposing;
  • Antibiotic Clinical Studies, Pharmacokinetics and Pharmacodynamics;
  • Clinical and Environmental Impact of Bacterial Biofilms;
  • Artificial Intelligence Strategies to Tackle Antibiotic Resistance.

Dr. Manuel Simões
Dr. Marc Maresca
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibiotics stewardship
  • antimicrobial use
  • antibiotics resistance
  • novel antimicrobial agents
  • multidisciplinary antimicrobial strategies
  • antibiotic clinical studies
  • artificial intelligence strategies

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Published Papers (1 paper)

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Review

26 pages, 2915 KiB  
Review
Recent Knowledge in the Application of Saccharomyces in Aquaculture: A Bibliometric and Narrative Review
by Elshafia Ali Hamid Mohammed, Béla Kovács and Károly Pál
Antibiotics 2025, 14(8), 736; https://doi.org/10.3390/antibiotics14080736 - 22 Jul 2025
Viewed by 423
Abstract
Aquaculture is a key food production sector responsible for meeting the nutritional needs of a rapidly growing global population. However, the emergence of disease outbreaks has become a major challenge for the aquaculture industry, resulting in significant economic losses. The use of costly [...] Read more.
Aquaculture is a key food production sector responsible for meeting the nutritional needs of a rapidly growing global population. However, the emergence of disease outbreaks has become a major challenge for the aquaculture industry, resulting in significant economic losses. The use of costly and toxic antibiotics for treatment has a negative impact on the aquatic environment. Consequently, there has been a growing interest in probiotics as a non-antibiotic approach to manage disease outbreaks and improve fish performance. The use of the yeast Saccharomyces cerevisiae (SC) has shown remarkable benefits in aquaculture. In February 2025, a systematic search was conducted based on the Web of Science (WoS) database for the period 2015–2025 to identify relevant studies investigating the beneficial effects of SC in aquaculture. After searching on WoS, 466 documents were found and analyzed using R-bibliometric package for comprehensive analysis to identify research gap, trends, and distribution of global literature that focuses on SC in aquaculture. The most relevant and recent articles were reviewed, summarized and discussed. The yeast SC have shown a wide range of benefits, including improved growth performance, feed efficiency, enhanced diversity of the gut microbiome and immune response. The implementation of SC is becoming a recent trend and its efficacy in aquatic environments has been thoroughly investigated. This review aims to provide a valuable insight into SC as one of the most important aquaculture probiotics. It also emphasizes the need for further research to fully understand its benefits and the way it works. Full article
(This article belongs to the Special Issue Challenges and Strategies for the Antibiotic Resistance Crisis)
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