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Proceedings, Volume 78, Issue 1

IECP 2020 2021 - 60 articles

The 1st International Electronic Conference on Pharmaceutics

Online | 1–15 December 2020

Volume Editors:
Andrea Erxleben, National University of Ireland, Ireland
Elisabetta Gavini, University of Sassari, Italy

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Cover Story: The 1st International Electronic Conference on Pharmaceutics (IECP 2020) brings together experts from academia and industry to share new ideas, technologies, and innovations in the broad areas of pharmaceutical formulation, process development, drug delivery, pharmacokinetics, and biopharmaceutics. This event is organized around the following general topics: formulation of poorly soluble drugs; cyclodextrins in pharmaceutics; electrospun–sprayed drug delivery systems; advances in pharmacokinetics and drug metabolism; transdermal and topical drug delivery; brain drug delivery; nanomedicine for cancer.

Articles (60)

  • Proceeding Paper
  • Open Access
1 Citations
1,939 Views
2 Pages

A Novel Hydrogel of Poloxamer 407-Chitosan-hyaluronic Acid as Possible Wound Healing in Skin and Mucosa

  • José L. Soriano-Ruiz,
  • Noelia Pérez-González,
  • Nuria Bozal-de Febrer,
  • María Rincón,
  • Beatriz Clares and
  • Ana C. Calpena

11 January 2021

The use of hydrogels in the treatment of wound healing is becoming an increasingly routine. [...]

  • Proceeding Paper
  • Open Access
1 Citations
1,568 Views
2 Pages

Novel Strategy for the Formulation of Poorly Water-Soluble Drugs: Nystatin Microencapsulation

  • Noelia Pérez-González,
  • María J. Martín-Villena,
  • Ana C. Calpena-Campmany,
  • José A. Morales-Molina and
  • Beatriz Clares-Naveros

4 December 2020

Background: In recent years, a growing concern about resistance to anti-infective agents has emerged1. One of the most common microbial agents is Candida albicans. Under certain conditions, C. albicans can cause infections of skin and mucosal tissue...

  • Proceeding Paper
  • Open Access
2 Citations
2,180 Views
7 Pages

1 December 2020

Iloperidone (ILO) is a second-generation antipsychotic drug and a first-line treatment approved by USFDA in May 2009. Iloperidone belongs to Biopharmaceutical Classification Systems (BCS) class II; thus, it is poorly water-soluble, highly permeable,...

  • Proceeding Paper
  • Open Access
1,568 Views
9 Pages

Ex Vivo and In Vivo Anti-inflammatory Evaluations of Modulated Flavanones Solutions

  • Paola Bustos-Salgado,
  • María J. Rodríguez-Lagunas,
  • Valeri Domínguez-Villegas,
  • Berenice Andrade-Carrera,
  • Ana Calpena-Campmany and
  • María Luisa Garduño-Ramírez

1 December 2020

Interest has developed in natural molecules due to their clinically proven effects on skin diseases. Flavanones display several biological activities, and recently have been the focus of studies due to their anti-inflammatory effect. To improve their...

  • Proceeding Paper
  • Open Access
1,428 Views
8 Pages

High-Throughput Electrospinning of Bioactive Scaffolds for Bone Regeneration

  • Herman Novik,
  • Marta Clerici,
  • Amir Fahmi,
  • Matej Buzgo and
  • Aiva Simaite

1 December 2020

Among the most promising technologies for sustained drug delivery systems are core-shell nanofibres prepared by electrospinning. However, the most common method for the production of those, coaxial electrospinning, suffers from extremely low flow rat...

  • Proceeding Paper
  • Open Access
2 Citations
1,548 Views
8 Pages

Monolein Aqueous Dispersions as a Tool to Increase Flavonoid Solubility: A Preliminary Study

  • Maddalena Sguizzato,
  • Elisabetta Esposito,
  • Markus Drechsler,
  • Supandeep Singh Hallan and
  • Rita Cortesi

1 December 2020

Topical application of flavonoids has recently received increased attention, however their use is limited due to a low aqueous solubility and related low in vivo absorption. Monolein emulsified in water leads to aqueous nanostructured dispersions of...

  • Proceeding Paper
  • Open Access
1,353 Views
2 Pages

Inclusion Complexes of New Ibuprofen Thiazolidin-4-Ones with β-Cyclodextrin

  • Ioana Vasincu,
  • Anca Roxana Petrovici,
  • Maria Apotrosoaei,
  • Florentina Lupașcu,
  • Narcisa Marangoci,
  • Mariana Pinteală and
  • Lenuța Profire

1 December 2020

(1) Background: Cyclodextrins are used in various areas due to their ability to form inclusion complexes and to modify some properties of the guest molecule. The characteristics that can be improved are related to the solubility of poorly water-solub...

  • Abstract
  • Open Access
1 Citations
1,441 Views
2 Pages

Synthesis and Characterization of a Novel Nanomicellar System Pluronic-PEI Suitable for Gene and Drug Co-Delivery in Cancer Therapy

  • Cátia Domingues,
  • Ivana Jarak,
  • Carla Varela,
  • Elisiário Tavares,
  • Fernanda Roleira,
  • Carmen Alvarez-Lorenzo,
  • Angel Concheiro,
  • Rui de Carvalho,
  • Francisco Veiga and
  • Marília Dourado
  • + 1 author

1 December 2020

Polyethyleneimine (PEI) is a synthetic cationic polymer recognized as a non-viral gene carrier with high transfection efficiency. However, cytotoxicity issues limit its use. Pluronic block-copolymers conjugated with PEI have demonstrated promising re...

  • Proceeding Paper
  • Open Access
3 Citations
2,618 Views
8 Pages

1 December 2020

Thermosensitive in situ gels are promising formulations for the management of Alzheimer’s disease (AD), since they increase the residence time of lipid-based nanosystems in the nasal cavity, improving drug therapeutic efficacy. The purpose of this st...

  • Proceeding Paper
  • Open Access
2 Citations
1,196 Views
8 Pages

1 December 2020

(1) Background: It is known that RNA in Na+ salt form has only immunomodulatory activity, and in acid form additionally acquires anti-inflammatory activity and in combination with D-mannitol acquires an even broader antiviral effect. The study aimed...

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Proceedings - ISSN 2504-3900Creative Common CC BY license