Proceedings, Volume 79, Issue 1

Dengue virus is a serious public health issue in tropical and subtropical regions. The global incidence of dengue necessitates the potent antiviral medication for the prevention of proliferation of the virus inside the human body. The DEN2 NS2B/NS3 p...

Since ancient times, plants have been used as preservatives, spices, flavorings and as natural remedies to prevent or treat diseases owing to the biological activity correlated with the bioactive compounds they contain. The avocado fruit (Persea amer...

Seaweeds are an important source of bioactive metabolites in the development of drugs and nutraceuticals. This study aimed to analyze the antiproliferative and apoptotic activities of the methanol extract (ME) of G. edulis using human Rhabdomyosarcom...

Present investigation assessed the hypoglycemic potential of hydro-alcoholic (HAE) and aqueous (AQE) extracts of Mehon, a commercial antidiabetic polyherbal formulation using various in vitro techniques. HAE and AQE were analyzed for α-amylase and α-...

2,5-diketopiperazines (DKP) are the simplest cyclo-peptides in nature, which could play a key role in the origin of life. They are ubiquitous in microorganisms, higher species, and in food and beverages. These dipeptides have been known since the beg...

Obesity, a global health concern, is associated with the dysbiosis of intestinal microbial composition. This study aims to investigate the potential of urolithin A (Uro-A) in reducing body weight gain through modulation of the gut microbiota. Rats we...

The aim of this review is to understand whether lentinan can be a useful integrative remedy for cancer patients. PubMed, EMBASE, Web of Science, Cochrane Library and Google Scholar were screened for relevant meta-analyses from inception to 29th Septe...

Central adiposity is one of the significant determinants of obesity-related hypertension risk, which may arise because of the pathogenic inflammatory nature of the abdominal fat depot. Pro-inflammatory cytokine and adipokine upregulation through nucl...

Cyclic ADP-ribose (cADPR, 1, Figure 1) is a naturally occurring metabolite of NAD+
capable of mobilizing Ca²⁺ ions from intracellular stores. [...]

The use of herbal products for the treatment, prevention and cure of diseases is one of the oldest human medicinal practices. In fact, the majority of the population in developing countries depend on ancestral plant knowledge for healthcare. However,...

Glycolysis inhibitors are currently considered as potential anticancer agents due to the fact that significant changes occur in tumor cells, known as metabolic reprogramming. However, carbohydrate metabolism inhibitors have pronounced systemic toxici...

Exhausted olive pomace (EOP) is a residue derived from the olive pomace oil industry. One of the main components of this agro-industrial residue is the extractive fraction which contains non-structural components such as bioactive compounds. In this...

Inhibition of tumor necrosis factor-alpha (TNF-α) has become a feasible target for alleviating inflammation-mediated diseases. Currently, techniques developed, such as anti-TNF antibody therapies, prove not to be nearly as beneficial enough to effect...

Olive leaves are a source of valuable compounds with applications in the phytopharmacy sector, among others. Nevertheless, there are untapped olive resources that can give new clues for the discovery of natural bioactive compounds. Therefore, in this...

Olea europea is among the most important potential plants of the Arabian Peninsula. It is commonly known as Zaytoun in Arabic. Olive leaves possess a wide array of pharmacological and medicinal attributes. Currently, process optimization for extracti...