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Tropical Medicine and Infectious Disease, Volume 7, Issue 8

August 2022 - 60 articles

Cover Story: Leishmaniasis is a neglected tropical disease that seriously influences global public health. Circular RNAs (circRNAs) are a new type of noncoding RNA that are involved in the regulation of biological and developmental processes. However, there is no published research on the function of circRNAs in leishmaniasis. This is the first study to explore the expression profiles of circRNAs in leishmaniasis. A total of 4664 significant differentially expressed circRNAs were identified and compared to those in control groups. Then, five hub genes (BRCA1, CREBBP, EP300, PIK3R1, and CRK) were identified. This study provides new evidence of the change in differentially expressed circRNAs and its potential function in leishmaniasis. These results may provide novel insights and evidence for the diagnosis and treatment of leishmaniasis. View this paper
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Articles (60)

  • Article
  • Open Access
19 Citations
4,447 Views
15 Pages

Evaluating Molecular Xenomonitoring as a Tool for Lymphatic Filariasis Surveillance in Samoa, 2018–2019

  • Brady McPherson,
  • Helen J. Mayfield,
  • Angus McLure,
  • Katherine Gass,
  • Take Naseri,
  • Robert Thomsen,
  • Steven A. Williams,
  • Nils Pilotte,
  • Therese Kearns and
  • Colleen L. Lau

Molecular xenomonitoring (MX), the detection of filarial DNA in mosquitoes using molecular methods (PCR), is a potentially useful surveillance strategy for lymphatic filariasis (LF) elimination programs. Delay in filarial antigen (Ag) clearance post-...

  • Article
  • Open Access
4 Citations
3,511 Views
14 Pages

Using Routinely Collected Health Records to Identify the Fine-Resolution Spatial Patterns of Soil-Transmitted Helminth Infections in Rwanda

  • Elias Nyandwi,
  • Tom Veldkamp,
  • Sherif Amer,
  • Eugene Ruberanziza,
  • Nadine Rujeni and
  • Ireneé Umulisa

Background. Soil-transmitted helminths (STH) are parasitic diseases with significant public health impact. Analysis is generally based on cross-sectional prevalence surveys; outcomes are mostly aggregated to larger spatial units. However, recent rese...

  • Article
  • Open Access
1 Citations
3,040 Views
14 Pages

Factors Affecting the Transition from Paper to Digital Data Collection for Mobile Tuberculosis Active Case Finding in Low Internet Access Settings in Pakistan

  • Christina Mergenthaler,
  • Jake D. Mathewson,
  • Abdullah Latif,
  • Hasan Tahir,
  • Vincent Meurrens,
  • Andreas van Werle,
  • Aamna Rashid,
  • Muhammad Tariq,
  • Tanveer Ahmed and
  • Ente Rood

Between September 2020 and March 2021, Mercy Corps piloted hybrid digital (CAPI) and paper-based (PAPI) data collection as part of its tuberculosis (TB) active case finding strategy. Data were collected using CAPI and PAPI at 140 TB chest camps in lo...

  • Article
  • Open Access
9 Citations
3,221 Views
10 Pages

Carbapenem-Resistant Organisms Isolated in Surgical Site Infections in Benin: A Public Health Problem

  • Carine Laurence Yehouenou,
  • Reza Soleimani,
  • Arsène A. Kpangon,
  • Anne Simon,
  • Francis M. Dossou and
  • Olivia Dalleur

An alarming worldwide increase in antimicrobial resistance is complicating the management of surgical site infections (SSIs), especially in low-middle income countries. The main objective of this study was to describe the pattern of carbapenem-resist...

  • Article
  • Open Access
10 Citations
3,099 Views
9 Pages

The Subjective Well-Being of Elderly Migrants in Dongguan: The Role of Residential Environment

  • Yuxi Liu,
  • Li Jia,
  • Junhui Xiao,
  • Qin Chen,
  • Qihui Gan,
  • Jie Huang,
  • Xianglei Zhu,
  • Chichen Zhang and
  • Chonghua Wan

To examine the association between community and individual-level residential environment in relation to subjective well-being (SWB) amongst 470 elderly migrants in China, this community-based survey was conducted. The manner and extent to which the...

  • Article
  • Open Access
11 Citations
3,143 Views
11 Pages

A Web of Science-Based Bibliometric Analysis of Global Noma Publications

  • Diego Azañedo,
  • Fabriccio J. Visconti-Lopez and
  • Akram Hernández-Vásquez

The World Health Organization recognizes noma as a global health problem and has suggested prioritizing research into this disease. A bibliographic search of original articles published in the Web of Science database up to 2022 was performed. A bibli...

  • Article
  • Open Access
6 Citations
3,566 Views
20 Pages

Transmission Dynamics and Genomic Epidemiology of Emerging Variants of SARS-CoV-2 in Bangladesh

  • Md. Abu Sayeed,
  • Jinnat Ferdous,
  • Otun Saha,
  • Shariful Islam,
  • Shusmita Dutta Choudhury,
  • Josefina Abedin,
  • Mohammad Mahmudul Hassan and
  • Ariful Islam

With the progression of the global SARS-CoV-2 pandemic, the new variants have become more infectious and continue spreading at a higher rate than pre-existing ones. Thus, we conducted a study to explore the epidemiology of emerging variants of SARS-C...

  • Article
  • Open Access
54 Citations
103,827 Views
13 Pages

Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents

  • Suyanee Mansanguan,
  • Prakaykaew Charunwatthana,
  • Watcharapong Piyaphanee,
  • Wilanee Dechkhajorn,
  • Akkapon Poolcharoen and
  • Chayasin Mansanguan

This study focuses on cardiovascular manifestation, particularly myocarditis and pericarditis events, after BNT162b2 mRNA COVID-19 vaccine injection in Thai adolescents. This prospective cohort study enrolled students aged 13–18 years from two...

  • Article
  • Open Access
8 Citations
3,623 Views
12 Pages

First Molecular Identification of Bulinus africanus in Lake Malawi Implicated in Transmitting Schistosoma Parasites

  • Mohammad H. Alharbi,
  • Cynthia Iravoga,
  • Sekeleghe A. Kayuni,
  • Lucas Cunningham,
  • E. James LaCourse,
  • Peter Makaula and
  • J. Russell Stothard

The freshwater snail genus Bulinus plays a vital role in transmitting parasites of the Schistosoma haematobium group. A hybrid schistosome between S. haematobium and S. mattheei has been recently detected using DNA-based identification methods in sch...

  • Article
  • Open Access
1 Citations
4,040 Views
12 Pages

Contributory Factors to Successful Tuberculosis Treatment in Southwest Nigeria: A Cross-Sectional Study

  • Olanrewaju Oladimeji,
  • Kelechi Elizabeth Oladimeji,
  • Mirabel Nanjoh,
  • Lucas Banda,
  • Olukayode Ademola Adeleke,
  • Teke Apalata,
  • Jabu Mbokazi and
  • Francis Leonard Mpotte Hyera

Tuberculosis (TB) is one of the oldest human diseases, and preventing treatment failure is critical. This is because TB cases pose a risk to the immediate and remote communities due to the potential for spread, particularly for multidrug-resistant (M...

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Trop. Med. Infect. Dis. - ISSN 2414-6366