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Commentary on COVID-19 Vaccine Hesitancy in sub-Saharan Africa
 
 
Opinion

Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa

1
Department of Parasitology, Institute of Tropical Medicine “Pedro Kourí”, Havana 11400, Cuba
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School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
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Department of Teaching, Polyclinic “Plaza de la Revolución”, Havana 11300, Cuba
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Department of Clinical Microbiology Diagnostic, Hospital Center of Institute of Tropical Medicine “Pedro Kourí”, Havana 11400, Cuba
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Department of Pathology, Hospital Center of Institute of Tropical Medicine “Pedro Kourí”, Havana 11400, Cuba
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Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, 41013 Sevilla, Spain
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Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain
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Depatamento de Medicina, Facultad de Medicina, Universidad de Sevilla, 41009 Sevilla, Spain
*
Authors to whom correspondence should be addressed.
Academic Editors: Peter A. Leggat, John Frean and Lucille Blumberg
Trop. Med. Infect. Dis. 2022, 7(8), 157; https://doi.org/10.3390/tropicalmed7080157
Received: 27 June 2022 / Revised: 26 July 2022 / Accepted: 27 July 2022 / Published: 30 July 2022
(This article belongs to the Special Issue COVID-19: Current Status and Future Prospects)
There is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection. View Full-Text
Keywords: pulmonary fibrosis; postacute COVID-19 syndrome; tuberculosis; helminth coinfection; sub-Saharan Africa pulmonary fibrosis; postacute COVID-19 syndrome; tuberculosis; helminth coinfection; sub-Saharan Africa
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MDPI and ACS Style

Fonte, L.; Acosta, A.; Sarmiento, M.E.; Norazmi, M.N.; Ginori, M.; de Armas, Y.; Calderón, E.J. Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa. Trop. Med. Infect. Dis. 2022, 7, 157. https://doi.org/10.3390/tropicalmed7080157

AMA Style

Fonte L, Acosta A, Sarmiento ME, Norazmi MN, Ginori M, de Armas Y, Calderón EJ. Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa. Tropical Medicine and Infectious Disease. 2022; 7(8):157. https://doi.org/10.3390/tropicalmed7080157

Chicago/Turabian Style

Fonte, Luis, Armando Acosta, María E. Sarmiento, Mohd Nor Norazmi, María Ginori, Yaxsier de Armas, and Enrique J. Calderón. 2022. "Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa" Tropical Medicine and Infectious Disease 7, no. 8: 157. https://doi.org/10.3390/tropicalmed7080157

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