You are currently viewing a new version of our website. To view the old version click .

Pathogens, Volume 14, Issue 3

March 2025 - 95 articles

Cover Story: HIV infection cannot be cured due to latently infected cells carrying intact but inactive HIV DNA, making them indistinguishable from uninfected cells. Several strategies have been developed to cure HIV infection, including the reactivation of HIV in latently infected cells, resulting in recognition and death—the “shock and kill” approach. Various latency-reversing agents (LRAs) have been tested in clinical trials. Some were successful in reactivating HIV in vivo and induced detectable changes in the reservoir. Though the technique is not yet curative, these trials prove that latently infected cells can be targeted. In combination with the latest immunomodulatory drugs that aid in killing cells that replicate HIV, new strategies and novel LRAs may be developed in the near future to cure HIV infection. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (95)

  • Article
  • Open Access
1,708 Views
20 Pages

Novel Techniques to Unravel Causative Bacterial Ecological Shifts in Chronic Urinary Tract Infection

  • Catherine C. Y. Chieng,
  • Qingyang Kong,
  • Natasha S. Y. Liou,
  • Mariña Neira Rey,
  • Katie L. Dalby,
  • Neil Jones,
  • Rajvinder Khasriya and
  • Harry Horsley

Chronic urinary tract infection (UTI) presents with protracted lower urinary tract symptoms and elevated urinary leukocyte counts, but its bacterial etiological agents remain obscure. In this cross-sectional investigation, we aimed to unravel the rol...

  • Article
  • Open Access
3 Citations
1,371 Views
13 Pages

Clonal Dissemination of NDM-Producing Proteus mirabilis in a Teaching Hospital in Sousse, Tunisia

  • Nadia Jaidane,
  • Lamia Tilouche,
  • Saoussen Oueslati,
  • Delphine Girlich,
  • Sana Azaiez,
  • Aymeric Jacquemin,
  • Laurent Dortet,
  • Walid Naija,
  • Abdelhalim Trabelsi and
  • Thierry Naas
  • + 2 authors

Proteus mirabilis (P. mirabilis) is an opportunistic pathogen involved in urinary tract infections as well as various nosocomial infections. Emerging resistances to beta-lactams in this species complicates potential treatment since it is intrinsicall...

  • Brief Report
  • Open Access
1,016 Views
8 Pages

Ocular Symptoms in Pre- and Perimenopausal Woman Infected with Demodex spp.

  • Danuta Kosik-Bogacka,
  • Natalia Łanocha-Arendarczyk,
  • Renata Pilarczyk,
  • Daria Schneider-Matyka,
  • Karolina Kot,
  • Konrad Grzeszczak,
  • Joanna Pyzia and
  • Elżbieta Grochans

The aim of this study was to determine the subjective ocular symptoms in pre- and perimenopausal women infected with Demodex folliculorum and D. brevis. Eyelashes were taken from pre- and perimenopausal women aged from 45 to 69 years (n = 253) and yo...

  • Article
  • Open Access
1,262 Views
14 Pages

Detection of Klebsiella pneumoniae in Veterinary and Food Matrices Using Loop-Mediated Isothermal Amplification

  • Icía Bermúdez-Fornos,
  • Alberto Cepeda,
  • Alejandro Garrido-Maestu and
  • Alexandre Lamas

Klebsiella pneumoniae is an opportunistic human pathogen of high relevance due to its ability to acquire antibiotic resistance. This pathogen is included, along with Enterococcus faecium, Staphylococcus aureus, Acinetobacter baumanii, Pseudomonas aer...

  • Article
  • Open Access
1 Citations
829 Views
12 Pages

Periodontitis is a chronic inflammatory disease characterized by bacterial infection and immune dysregulation. Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) is a key pathogen linked to disease progression. Caspase-1 and caspase-4 r...

  • Article
  • Open Access
4 Citations
1,508 Views
16 Pages

Molecular Characterization and Antimicrobial Resistance Evaluation of Listeria monocytogenes Strains from Food and Human Samples

  • Annamaria Castello,
  • Vincenzina Alio,
  • Marina Torresi,
  • Gabriella Centorotola,
  • Alexandra Chiaverini,
  • Francesco Pomilio,
  • Ignazio Arrigo,
  • Anna Giammanco,
  • Teresa Fasciana and
  • Marco Francesco Ortoffi
  • + 4 authors

Listeria monocytogenes is an important foodborne pathogen, markedly persistent even in harsh environments and responsible for high hospitalization and mortality rates. The aim of the present study was to detect the strains circulating in Sicily over...

  • Review
  • Open Access
1 Citations
4,429 Views
25 Pages

The human microbiome plays a vital role in maintaining human homeostasis, acting as a key regulator of host immunity and defense mechanisms. However, dysbiotic microbial communities may cause disruption of the symbiotic relationship between the host...

  • Article
  • Open Access
2 Citations
1,607 Views
13 Pages

Genomic Diversity, Virulome, and Resistome of Streptococcus agalactiae in Northeastern Brazil: Are Multi-Host Adapted Strains Rising?

  • Vinicius Pietta Perez,
  • Luciana Roberta Torini,
  • Fernanda Zani Manieri,
  • Suellen Bernardo de Queiroz,
  • Jorhanna Isabelle Araujo de Brito Gomes,
  • Lauro Santos Filho,
  • Eloiza Helena Campana,
  • Celso Jose Bruno de Oliveira,
  • Eduardo Sergio Soares Sousa and
  • Ilana Lopes Baratella Cunha Camargo

Streptococcus agalactiae, known as group B streptococci (GBS), colonizes the digestive and genitourinary tracts and causes neonatal diseases and infections in immunocompromised and elderly individuals. GBS neonatal disease prevention includes intrapa...

  • Article
  • Open Access
1 Citations
1,263 Views
15 Pages

Expanded Gram-Negative Activity of Marinopyrrole A

  • Clare F. Euteneuer,
  • Brianna N. Davis,
  • LeeAnna M. Lui,
  • Andrew J. Neville and
  • Paul H. Davis

The rise of bacterial infections is a global health issue that calls for the development and availability of additional antimicrobial agents. Known for its in vitro effects on Gram-positive organisms, the drug-like small molecule marinopyrrole A was...

  • Systematic Review
  • Open Access
4 Citations
1,669 Views
17 Pages

Food safety is a paramount public health concern, particularly with the rise of antimicrobial-resistant bacteria. This systematic review explores the efficacy of bacteriophages as a novel and environmentally sustainable approach to controlling multi-...

of 10

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Pathogens - ISSN 2076-0817