2025 November - 117 articles
Enteritis is a common and recurrent disease in shrimp aquaculture, causing significant economic losses and management challenges. However, its specific causative pathogen remains unclear. Here, a pathogen strain, Vibrio parahaemolyticus VSP1, was dir...
Antimicrobial resistance in healthcare-associated infections represents one of the greatest threats to global health. The COVID-19 pandemic disrupted infection control and antimicrobial stewardship, potentially affecting the prevalence of pathogens a...
Introduction: This study was designed to determine the differences between brucellosis patients whose standard tube agglutination test (SAT) titers decreased or not after successful treatment. Methods: This retrospective study included patients with...
Rheumatic heart disease (RHD) remains a major cause of preventable morbidity in low- and middle-income countries. As the most serious sequel of acute rheumatic fever (ARF) caused by Streptococcus pyogenes, RHD arises from molecular mimicry that drive...
The Journal retracts the article “Rapid Generation of Coronaviral Immunity Using Recombinant Peptide Modified Nanodiamonds” [...]
Feline calicivirus (FCV) is widespread in multi-cat environments and typically causes acute upper respiratory tract disease (URTD). FCV also causes outbreaks of virulent systemic disease (VSD), mainly in adults, with multiple organ involvement. In th...
Borrelia garinii is a spirochete associated with Lyme borreliosis and is widely distributed across Eurasia. Although its genomic features have been well characterized in Europe, genomic data from East Asian isolates remain limited. Two B. garinii str...
Background: Escherichia coli is a cause of severe clinical bovine mastitis; however, it is not yet fully understood what makes mastitis-associated bacteria different from commensal strains at the genetic level. The goal of this study was to compare t...
Blood transfusions are indispensable in Veterinary Medicine, providing therapeutic support in cases of hematological disorders. Several pathogens can cause disease and/or exacerbate the condition of immunocompromised dogs or those requiring a transfu...
Bromoepiandrosterone (BEA), a synthetic analog of the adrenal steroid DHEA, holds promise as a host-directed therapy for both active and latent tuberculosis (TB). Unlike DHEA, BEA lacks hormonal side effects yet retains potent immunomodulatory activi...
Salmonella species isolated from chicken meat pose an increasing threat to public health. According to ECDC data, salmonellosis cases have shown a significant upward trend in many European countries between 2019 and 2023, almost reaching pre-pandemic...
Pangenotypic direct-acting antivirals (pDAAs) have transformed hepatitis C virus (HCV) treatment. In Italy, sofosbuvir/velpatasvir (SOF/VEL) and glecaprevir/pibrentasvir (GLE/PIB) are available. While both show similar efficacy, differences in patien...
Proteus mirabilis (P. mirabilis) serves as a multi-host–pathogen regarded as an alarming foodborne infectious disease, causing illnesses of variable severity in both livestock and human beings. The present study aimed to estimate the prevalence...
The ecological role and overlap with urban environments make wild carnivores useful epidemiological sentinels for several pathogens. The present study aimed to investigate the seroprevalence of Toxoplasma gondii, Neospora caninum and Encephalitozoon ...
Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD) with complex infectious and non-infectious etiologies. Bacterial pathogens, including Streptococcus pneumoniae, Haemophilus influenzae, and atypical organisms...
Bacterial liver abscess (BLA), accounting for approximately 80% of all liver abscesses, is a severe suppurative infection of the liver. Although gut microbiota dysbiosis has been implicated in BLA pathogenesis, causal evidence remains limited. Here,...
The porcine origin rotavirus A (RVA) G5 genotype is notable for its unique and sustained human circulation in Brazil, primarily as G5P[8] during the 1980s–2000s. This study aimed to characterize and investigate the full genome of a rare G5P[6]...
Swine respiratory disease (SRD) is a complex interaction whereby viral infection predisposes the host to secondary bacterial pulmonary invasion, which may be fatal. Antimicrobial agents remain an important therapy and serve to reduce morbidity and mo...
Toxoplasma gondii and Neospora caninum are intracellular protozoan parasites that cause reproductive failure and production losses in ruminants. Considering the limited information on the epidemiology of these infections in goats in different climate...
Rotavirus alphagastroenteritidis remains the leading cause of severe gastroenteritis in children under five years, despite widespread vaccine use. The COVID-19 pandemic disrupted healthcare and vaccination delivery, while non-pharmacological interven...
Free-ranging hens are at risk of infection by parasites characterized by certain stages that develop in the soil until attaining the infective phase. To analyze the usefulness of a biological control strategy of helminths affecting pasturing hens, fe...
West Nile fever is a mosquito-borne zoonotic disease caused by West Nile virus (WNV), maintained in an enzootic cycle between avian hosts and Culex mosquitoes. While birds are the principal reservoirs, WNV also infects a wide range of mammals, includ...
Chlamydia trachomatis infection causes pelvic inflammatory disease and infertility, but how host immune factors control pathogen clearance or pathology is not fully understood. Using a mouse model of genital tract infection with Chlamydia muridarum,...
Acinetobacter baumanni (A. baumannii) is a well-known pathogen associated with antimicrobial-resistant infections. It is a major cause of nosocomial infections and is frequently associated with polymicrobial and antibiotic-resistant infections. This...
Type-P5 ATPases are the least characterized among the P-type ATPases and this is especially true in the case of the malaria parasite. In this study, Spf1, a subtype-P5A ATPase of yeast, and ATP13A2, a subtype-P5B ATPase of humans, were used as templa...
Oncogenic viruses are well-established contributors to cancer development in both humans and animals. While many animal oncogenic viruses exhibit strong host specificity, concerns remain about their potential to cross species barriers and impact huma...
This study presents a model investigation into the development of tolerance to polyene antifungal drugs (nystatin and natamycin) in strains of Malassezia pachydermatis. This species, commonly associated with external ear canal infections in dogs, has...
The genus Aeromonas is widely distributed in aquatic environments, where it is a frequent fish pathogen. It has also been described in association with human infections, with most cases caused by A. caviae, A. veronii biovar sobria, and A. hydrophila...
There was an error in the original publication [...]
This study investigated the long-term trends in human parainfluenza virus (HPIV) types 1, 2, and 3 in Korea by year, age group, and season. A total of 23,284 nasopharyngeal swabs collected from patients with respiratory symptoms at a tertiary hospita...
Enterocytozoon bieneusi is the most frequently diagnosed microsporidian parasite in humans and a recognized cause of diarrheal disease, particularly in immunocompromised individuals. Its broad host range, which includes livestock, companion animals,...
Human herpesvirus 6 (HHV-6) is a common virus that can reactivate in immunocompromised patients, including lung transplant (LT) recipients. This study aimed to evaluate the clinical and functional implications of HHV-6 infection in LT patients throug...
Arboviruses such as dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) remain major global health threats, especially in tropical regions, with no effective antiviral treatments available. Recent research highlights progress in identifying antiviral...
The consumption of raw milk has been demonstrated to carry a potential risk of transmission of Campylobacter spp., with Campylobacter jejuni (C. jejuni) and Campylobacter coli (C. coli) being the major causes for foodborne gastroenteritis cases. The...
Background: Escherichia coli (E. coli) bacteremia is a significant cause of mortality, particularly in older adults. Limited data exists on clinical outcomes in octogenarians. This study aims to evaluate the clinical outcomes of E. coli bacterem...
Multidrug-resistant (MDR) bloodstream infections (BSIs) constitute a major challenge in intensive care units, with the COVID-19 pandemic compromising infection control and potentially increasing MDR incidence. Comparative data between COVID and non-C...
Nature has long served as a prolific source of bioactive compounds, offering structurally diverse scaffolds for the development of therapeutics. In recent years, increasing attention has been given to nature-inspired covalent inhibitors, molecules th...
Zika virus (ZIKV) was first identified in Africa in the mid-20th century and circulated for decades with limited and often unnoticed human cases. This situation changed with the emergence of the Asian lineage, responsible for large outbreaks in the P...
Paratuberculosis (Johne’s disease) is a chronic enteric infection of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP), leading to significant economic losses in livestock production. While the solute carrier family 11 membe...
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits remarkable developmental plasticity that enables its survival across distinct environments within the insect vector and mammalian host. This review focuses on two critical different...
Syphilis, a curable sexually transmitted infection, has resurged globally, challenging public health systems in both high-income countries and low- and middle-income countries (LMICs). In nations like the United States, the United Kingdom, parts of E...
Ticks use multiple sensory organs to facilitate host detection, including Haller’s organs (HOs) that allow ticks to sense infrared (IR) radiation from potential hosts. Additionally, ticks have primitive eyes to sense light sources. The possibil...
Background: Pseudomonas aeruginosa infection is a major driver of morbidity and mortality in cystic fibrosis (CF), yet disease severity varies widely among people with CF (pwCF). This clinical heterogeneity suggests the involvement of host genet...
Autism spectrum disorder is markedly heterogeneous and frequently accompanied by gastrointestinal symptoms that often correlate with behavioral phenotypes. Emerging evidence suggests that the microbiota–gut–brain axis may contribute to th...
Background: Cerebral echinococcosis is a rare, potentially serious parasitic disease in children, that can lead to intracranial hypertension, focal neurological deficits, seizures, and severe complications. We conducted a systematic review and meta-a...
Human adenoviruses (HAdVs; genus Mastadenovirus, family Adenoviridae) are major etiologic agents of respiratory infections, exerting a disproportionately large impact on children. However, no long-term study to date has spanned pre- and post-pandemic...
Avian influenza (AI) is a highly contagious viral disease affecting both domestic and wild birds, posing a significant threat to poultry farming worldwide. This study aims to analyze the key landscape and population factors associated with H7 avian i...
Ventilator-associated pneumonia (VAP) is one of the most common hospital-acquired infections. Several studies have explored the potential role of the lung microbiome as a biomarker for identifying and predicting the prognosis of VAP. However, researc...
Urticaria is a skin disorder characterized by erythematous, edematous, and pruritic lesions. Intestinal microorganisms can trigger various immunological responses, and Blastocystis has been suggested to affect gut-associated lymphoid tissue homeostas...
Calcineurin (CaN), a Ca2+-dependent phosphatase, plays key roles in eukaryotic cell signaling. We investigated whether Leishmania amazonensis’ two infective forms—promastigotes and amastigotes—exhibit differences in CaN expression,...
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