Current Progress on Bacterial Antimicrobial Resistance

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 402

Special Issue Editor


E-Mail Website
Guest Editor
1. Department of Veterinary Sciences, University of Pisa, Pisa, Italy
2. Interdepartmental Research Center “Nutraceuticals and Food for Health”, University of Pisa, Pisa, Italy
Interests: zoonosis; arthropod-borne infections; leptospirosis; enteropathogens; antibiotic resistance
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) is a current and relevant threat worldwide, affecting humans as well as livestock, pets, and wildlife. The spread of resistant bacterial strains compromises the effectiveness of previously effective antibiotics, making several common infections difficult to treat.

It has been estimated that AMR could become the leading global cause of death by 2050; therefore, control measures must be implemented. Monitoring the bacteria characterized by old and new antimicrobial resistance is pivotal to understanding the epidemiological situation in humans and animals in relation to different environments and geographical areas, in order to set up appropriate preventive measures.

This Special Issue aims to collect significant contributions regarding the factors that contribute to the emergence, dissemination, management, and control of antimicrobial-resistant bacteria. Studies on the molecular mechanisms, clinical implications, and epidemiological dimensions of AMR are welcome.

We invite the researchers to contribute through research articles, reviews, short communications, and case reports.

Dr. Valentina Virginia Ebani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • animals
  • humans
  • environments
  • epidemiology
  • molecular mechanisms of resistance
  • clinical implications
  • One Health
  • antimicrobial resistance
  • bacteria

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

12 pages, 228 KiB  
Article
Determination of Minimum Inhibitory Concentrations of Selected Antibiotics Against Trueperella pyogenes Originated from Bovine Clinical Endometritis
by Ottó Szenci, Ákos Jerzsele, Zoltán Somogyi, Ádám Kerek, Attila Répási, Lea Lénárt and László Makrai
Pathogens 2025, 14(5), 405; https://doi.org/10.3390/pathogens14050405 - 24 Apr 2025
Viewed by 202
Abstract
Bacteriological examination of uterine secretions provides essential information for the prevalence of bovine uterine pathogens and their influence on fertility. The objective of the present study was to determine the uterine pathogens in cases of clinical endometritis in two Holstein-Friesian dairy farms between [...] Read more.
Bacteriological examination of uterine secretions provides essential information for the prevalence of bovine uterine pathogens and their influence on fertility. The objective of the present study was to determine the uterine pathogens in cases of clinical endometritis in two Holstein-Friesian dairy farms between 21 and 27 days after calving and the minimum inhibitory concentration (MIC) of 14 antimicrobials for Trueperella pyogenes (T. pyogenes). Overall, the prevalence of T. pyogenes (Farms A and B) was 46.3% and 22% (p < 0.01), respectively. In contrast, Farm B had significantly more cases (p < 0.001) of Escherichia coli, but the distribution of uterine pathogens was similar. Regarding the prevalence of any bacteria, Farm B also had significantly more bacteria (p < 0.001) than Farm A. T. pyogenes isolates were highly susceptible to amoxicillin, amoxicillin/clavulanic acid, tylosin, and cephalosporins, such as ceftiofur, cefquinome, and cephalexin with MIC90 of ≤2 μg/mL. At the same time, MIC90 of tulathromycin, lincomycin, and florfenicol were between 4 and 8 μg/mL and of doxycycline, enrofloxacin, oxytetracycline, and gentamicin, were between 16 and 32 μg/mL, respectively. Meanwhile, sulfamethoxazole/trimethoprim showed the highest MIC90 (>32 μg/mL). In summary, T. pyogenes with high MIC90 against oxytetracycline, gentamicin, and sulfamethoxazole/trimethoprim were found, which calls attention to the prudent use of antibiotics. Full article
(This article belongs to the Special Issue Current Progress on Bacterial Antimicrobial Resistance)
Back to TopTop