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Nutrients, Volume 9, Issue 2

February 2017 - 94 articles

Cover Story: Metabolic vulnerability is associated with age-related diseases and concomitant co-morbidities, which include obesity, diabetes, atherosclerosis and cancer. Phenotypic heterogeneity and individual response to metabolic stressors are closely related food intake. Understanding the complexity of the relationship between dietary provision and metabolic consequences in the long term might provide clinical strategies to improve healthspan. New aspects of metformin activity provide a link to many of the overlapping factors, especially the way in which organismal bioenergetics remodel one-carbon metabolism. Metformin not only inhibits mitochondrial complex 1, modulating the metabolic response to nutrient intake, but also alters one-carbon metabolic pathways. View this paper
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Articles (94)

  • Article
  • Open Access
30 Citations
9,757 Views
12 Pages

The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk

  • Brodie Daniels,
  • Stefan Schmidt,
  • Tracy King,
  • Kiersten Israel-Ballard,
  • Kimberly Amundson Mansen and
  • Anna Coutsoudis

22 February 2017

A pasteurization temperature monitoring system has been designed using FoneAstra, a cellphone-based networked sensing system, to monitor simulated flash-heat (FH) pasteurization. This study compared the effect of the FoneAstra FH (F-FH) method with t...

  • Article
  • Open Access
17 Citations
9,076 Views
13 Pages

22 February 2017

Iodine deficiency during the first two years of life may cause irreversible brain damage and mental retardation. The aim of the present study was to investigate, for the first time, the effect of iodine fortified milk on the iodine status of lactatin...

  • Article
  • Open Access
59 Citations
10,589 Views
7 Pages

Antiosteoporotic Activity of Genistein Aglycone in Postmenopausal Women: Evidence from a Post-Hoc Analysis of a Multicenter Randomized Controlled Trial

  • Vincenzo Arcoraci,
  • Marco Atteritano,
  • Francesco Squadrito,
  • Rosario D’Anna,
  • Herbert Marini,
  • Domenico Santoro,
  • Letteria Minutoli,
  • Sonia Messina,
  • Domenica Altavilla and
  • Alessandra Bitto

22 February 2017

Genistein has a preventive role against bone mass loss during menopause. However, experimental data in animal models of osteoporosis suggest an anti-osteoporotic potential for this isoflavone. We performed a post-hoc analysis of a previously publishe...

  • Article
  • Open Access
25 Citations
7,742 Views
18 Pages

Age-Related Loss in Bone Mineral Density of Rats Fed Lifelong on a Fish Oil-Based Diet Is Avoided by Coenzyme Q10 Addition

  • Alfonso Varela-López,
  • Julio J. Ochoa,
  • José M. Llamas-Elvira,
  • Magdalena López-Frías,
  • Elena Planells,
  • MCarmen Ramirez-Tortosa,
  • Cesar L. Ramirez-Tortosa,
  • Francesca Giampieri,
  • Maurizio Battino and
  • José L. Quiles

22 February 2017

During aging, bone mass declines increasing osteoporosis and fracture risks. Oxidative stress has been related to this bone loss, making dietary compounds with antioxidant properties a promising weapon. Male Wistar rats were maintained for 6 or 24 mo...

  • Article
  • Open Access
49 Citations
9,442 Views
13 Pages

Zinc Status Biomarkers and Cardiometabolic Risk Factors in Metabolic Syndrome: A Case Control Study

  • Erika P. S. Freitas,
  • Aline T. O. Cunha,
  • Sephora L. S. Aquino,
  • Lucia F. C. Pedrosa,
  • Severina C. V. C. Lima,
  • Josivan G. Lima,
  • Maria G. Almeida and
  • Karine C. M. Sena-Evangelista

22 February 2017

Metabolic syndrome (MS) involves pathophysiological alterations that might compromise zinc status. The aim of this study was to evaluate zinc status biomarkers and their associations with cardiometabolic factors in patients with MS. Our case control...

  • Review
  • Open Access
60 Citations
17,376 Views
12 Pages

22 February 2017

Many articles have discussed the relationship between fructose consumption and the incidence of obesity and related diseases. Fructose is absorbed in the intestine and metabolized in the liver to glucose, lactate, glycogen, and, to a lesser extent, l...

  • Article
  • Open Access
45 Citations
6,981 Views
11 Pages

Mediterranean Diet and Its Correlates among Adolescents in Non-Mediterranean European Countries: A Population-Based Study

  • Dario Novak,
  • Lovro Štefan,
  • Rebeka Prosoli,
  • Arunas Emeljanovas,
  • Brigita Mieziene,
  • Ivana Milanović and
  • Snežana Radisavljević-Janić

22 February 2017

Little is known about the factors which might influence the adherence to a Mediterranean diet in non-Mediterranean European countries. Thus, the main purpose of this study was to determine the associations between socioeconomic, psychological, and ph...

  • Review
  • Open Access
279 Citations
20,017 Views
27 Pages

21 February 2017

With recent insight into the development of dietary supplements and functional foods, search of effective phytochemical compounds and their mechanisms involved in prevention and management of diabetes and its complications are now being assessed. Cin...

  • Article
  • Open Access
13 Citations
10,185 Views
13 Pages

Metabolic Effects of Glucose-Fructose Co-Ingestion Compared to Glucose Alone during Exercise in Type 1 Diabetes

  • Lia Bally,
  • Patrick Kempf,
  • Thomas Zueger,
  • Christian Speck,
  • Nicola Pasi,
  • Carlos Ciller,
  • Katrin Feller,
  • Hannah Loher,
  • Robin Rosset and
  • Matthias Wilhelm
  • + 5 authors

21 February 2017

This paper aims to compare the metabolic effects of glucose-fructose co-ingestion (GLUFRU) with glucose alone (GLU) in exercising individuals with type 1 diabetes mellitus. Fifteen male individuals with type 1 diabetes (HbA1c 7.0% ± 0.6% (53 ± 7 mmol...

  • Article
  • Open Access
25 Citations
7,163 Views
11 Pages

Hypoallergenic Variant of the Major Egg White Allergen Gal d 1 Produced by Disruption of Cysteine Bridges

  • Pathum Dhanapala,
  • Dulashi Withanage-Dona,
  • Mimi L. K. Tang,
  • Tim Doran and
  • Cenk Suphioglu

21 February 2017

Background: Gal d 1 (ovomucoid) is the dominant allergen in the chicken egg white. Hypoallergenic variants of this allergen can be used in immunotherapy as an egg allergy treatment approach. We hypothesised that disruption of two of the nine cysteine...

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Nutrients - ISSN 2072-6643