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37 Results Found

  • Article
  • Open Access
7 Citations
3,366 Views
13 Pages

Identification of Genomic Regions and Candidate Genes for Litter Traits in French Large White Pigs Using Genome-Wide Association Studies

  • Jianmei Chen,
  • Ziyi Wu,
  • Ruxue Chen,
  • Zhihui Huang,
  • Xuelei Han,
  • Ruimin Qiao,
  • Kejun Wang,
  • Feng Yang,
  • Xin-Jian Li and
  • Xiu-Ling Li

19 June 2022

The reproductive traits of sows are one of the important economic traits in pig production, and their performance directly affects the economic benefits of the entire pig industry. In this study, a total of 895 French Large White pigs were genotyped...

  • Article
  • Open Access
2 Citations
1,963 Views
16 Pages

Genome Selection and Genome-Wide Association Analyses for Litter Size Traits in Large White Pigs

  • Yifeng Hong,
  • Xiaoyan He,
  • Dan Wu,
  • Jian Ye,
  • Yuxing Zhang,
  • Zhenfang Wu and
  • Cheng Tan

11 June 2025

(1) Background: Litter size traits are critical for pig breeding efficiency but pose challenges due to low heritability and sex-limited influences. This study aimed to elucidate the genetic architecture and identify candidate genes for these traits i...

  • Article
  • Open Access
9 Citations
5,476 Views
17 Pages

Single-Step Genome Wide Association Study Identifies QTL Signals for Untrimmed and Trimmed Thigh Weight in Italian Crossbred Pigs for Dry-Cured Ham Production

  • Valentino Palombo,
  • Mariasilvia D’Andrea,
  • Danilo Licastro,
  • Simeone Dal Monego,
  • Sandy Sgorlon,
  • Misa Sandri and
  • Bruno Stefanon

29 May 2021

Protected Designation of Origin (PDO) dry-cured ham is the most important product in the Italian pig breeding industry, mainly oriented to produce heavy pig carcasses to obtain hams of the right weight and maturity. Recently, along with the tradition...

  • Article
  • Open Access
5 Citations
2,752 Views
14 Pages

Genomic Regions Associated with Resistance to Gastrointestinal Parasites in Australian Merino Sheep

  • Brenda Vera,
  • Elly A. Navajas,
  • Pablo Peraza,
  • Beatriz Carracelas,
  • Elize Van Lier and
  • Gabriel Ciappesoni

27 June 2024

The objective of this study was to identify genomic regions and genes associated with resistance to gastrointestinal nematodes in Australian Merino sheep in Uruguay, using the single-step GWAS methodology (ssGWAS), which is based on genomic estimated...

  • Article
  • Open Access
10 Citations
2,745 Views
15 Pages

Identification of Candidate Genes and Pathways Linked to the Temperament Trait in Sheep

  • Estefanía Romaniuk,
  • Brenda Vera,
  • Pablo Peraza,
  • Gabriel Ciappesoni,
  • Juan Pablo Damián and
  • Elize Van Lier

11 February 2024

Temperament can be defined as the emotional variability among animals of the same species in response to the same stimulus, grouping animals by their reactivity as nervous, intermediate, or calm. Our goal was to identify genomic regions with the temp...

  • Article
  • Open Access
22 Citations
4,599 Views
16 Pages

Genome-Wide Association Study of Parasite Resistance to Gastrointestinal Nematodes in Corriedale Sheep

  • Beatriz Carracelas,
  • Elly A. Navajas,
  • Brenda Vera and
  • Gabriel Ciappesoni

27 August 2022

Selection of genetically resistant animals is one alternative to reduce the negative impact of gastrointestinal nematodes (GIN) on sheep production. The aim of this study was to identify genomic regions associated with GIN resistance in Corriedale sh...

  • Article
  • Open Access
989 Views
20 Pages

Multivariate Single-Step GWAS Reveals Pleiotropic Genomic Regions and Candidate Genes Associated with Male Scrotal Circumference and Female Fertility Traits in Retinta Beef Cattle

  • Chiraz Ziadi,
  • Rosa María Morales,
  • María Ángeles Vargas-Pérez,
  • Gabriel Anaya Calvo-Rubio,
  • Sebastián Demyda-Peyrás and
  • Antonio Molina

11 October 2025

Fertility is key for calf production. Direct selection for female fertility under field conditions is hindered by low accuracy and selection response. An alternative widely implemented is selection for scrotal circumference (SC), genetically correlat...

  • Article
  • Open Access
6 Citations
2,991 Views
17 Pages

A Single-Step Genome-Wide Association Study for Semen Traits of Egyptian Buffalo Bulls

  • Ayman G. EL Nagar,
  • Mohamed M. I. Salem,
  • Amin M. S. Amin,
  • Maher H. Khalil,
  • Ayman F. Ashour,
  • Mohammed M. Hegazy and
  • Hamdy Abdel-Shafy

5 December 2023

The present study aimed to contribute to the limited research on buffalo (Bubalus bubalis) semen traits by incorporating genomic data. A total of 8465 ejaculates were collected. The genotyping procedure was conducted using the Axiom® Buffalo Geno...

  • Article
  • Open Access
15 Citations
5,984 Views
27 Pages

Haplotype-Based Single-Step GWAS for Yearling Temperament in American Angus Cattle

  • Andre C. Araujo,
  • Paulo L. S. Carneiro,
  • Amanda B. Alvarenga,
  • Hinayah R. Oliveira,
  • Stephen P. Miller,
  • Kelli Retallick and
  • Luiz F. Brito

22 December 2021

Behavior is a complex trait and, therefore, understanding its genetic architecture is paramount for the development of effective breeding strategies. The objective of this study was to perform traditional and weighted single-step genome-wide associat...

  • Article
  • Open Access
10 Citations
5,910 Views
10 Pages

Detection of Genomic Regions with Pleiotropic Effects for Growth and Carcass Quality Traits in the Rubia Gallega Cattle Breed

  • Maria Martinez-Castillero,
  • Carlos Then,
  • Juan Altarriba,
  • Houssemeddine Srihi,
  • David López-Carbonell,
  • Clara Díaz,
  • Paulino Martinez,
  • Miguel Hermida and
  • Luis Varona

4 June 2021

The breeding scheme in the Rubia Gallega cattle population is based upon traits measured in farms and slaughterhouses. In recent years, genomic evaluation has been implemented by using a ssGBLUP (single-step Genomic Best Linear Unbiased Prediction)....

  • Article
  • Open Access
7 Citations
3,158 Views
19 Pages

Genome-Wide Association Study of Conformation Traits in Brazilian Holstein Cattle

  • Emanueli F. P. Silva,
  • Rita C. Gaia,
  • Henrique A. Mulim,
  • Luís Fernando Batista Pinto,
  • Laiza H. S. Iung,
  • Luiz F. Brito and
  • Victor B. Pedrosa

25 August 2024

The linear conformation of animals exerts an influence on health, reproduction, production, and welfare, in addition to longevity, which directly affects the profitability of milk-producing farms. The objectives of this study were (1) to perform geno...

  • Feature Paper
  • Article
  • Open Access
879 Views
18 Pages

Genetic Parameters, Linear Associations, and Genome-Wide Association Study for Endotoxin-Induced Cortisol Response in Holstein heifers

  • Bruno A. Galindo,
  • Umesh K. Shandilya,
  • Ankita Sharma,
  • Flavio S. Schenkel,
  • Angela Canovas,
  • Bonnie A. Mallard and
  • Niel A. Karrow

26 June 2025

Lipopolysaccharide (LPS) endotoxin is a well-characterized microbe-associated molecular pattern (MAMP) that forms the outer membrane of both pathogenic and commensal Gram-negative bacteria. It plays a crucial role in triggering inflammatory disorders...

  • Article
  • Open Access
1 Citations
1,527 Views
15 Pages

Enhancing Genomic Prediction Accuracy with a Single-Step Genomic Best Linear Unbiased Prediction Model Integrating Genome-Wide Association Study Results

  • Zhixu Pang,
  • Wannian Wang,
  • Pu Huang,
  • Hongzhi Zhang,
  • Siying Zhang,
  • Pengkun Yang,
  • Liying Qiao,
  • Jianhua Liu,
  • Yangyang Pan and
  • Wenzhong Liu
  • + 1 author

29 April 2025

Genomic selection (GS) is a genetic breeding method that uses genome-wide marker information to improve the accuracy of the prediction of complex traits. The single-step GBLUP (ssGBLUP) model, which integrates pedigree, phenotypic, and genomic data,...

  • Article
  • Open Access
2 Citations
2,308 Views
10 Pages

Genetic Variants Associated with Sensitive Skin: A Genome-Wide Association Study in Korean Women

  • Seoyoung Kim,
  • Kyung-Won Hong,
  • Mihyun Oh,
  • Susun An,
  • Jieun Han,
  • Sodam Park,
  • Goun Kim and
  • Jae Youl Cho

22 October 2024

Sensitive skin (SS) is associated with discomfort, including burning, stinging, and itching. These symptoms are often exacerbated by environmental factors and personal care products. In this genome-wide association study (GWAS), we aimed to identify...

  • Article
  • Open Access
6 Citations
2,689 Views
21 Pages

Sclerotinia sclerotiorum (Ss) is one of the most devastating fungal pathogens, causing huge yield loss in multiple economically important crops including oilseed rape. Plant resistance to Ss pertains to quantitative disease resistance (QDR) controlle...

  • Article
  • Open Access
3 Citations
1,699 Views
13 Pages

Genome-Wide Association Study and Genomic Prediction of Soybean Mosaic Virus Resistance

  • Di He,
  • Xintong Wu,
  • Zhi Liu,
  • Qing Yang,
  • Xiaolei Shi,
  • Qijian Song,
  • Ainong Shi,
  • Dexiao Li and
  • Long Yan

27 February 2025

Soybean mosaic virus (SMV), a pathogen responsible for inducing leaf mosaic or necrosis symptoms, significantly compromises soybean seed yield and quality. According to the classification system in the United States, SMV is categorized into seven dis...

  • Article
  • Open Access
19 Citations
3,668 Views
13 Pages

Genome-Wide Association Study Reveals the QTLs for Seed Storability in World Rice Core Collections

  • Fangxi Wu,
  • Xi Luo,
  • Lingqiang Wang,
  • Yidong Wei,
  • Jianguo Li,
  • Huaan Xie,
  • Jianfu Zhang and
  • Guosheng Xie

20 April 2021

Seed storability is a main agronomically important trait to assure storage safety of grain and seeds in rice. Although many quantitative trait loci (QTLs) and associated genes for rice seed storability have been identified, the detailed genetic mecha...

  • Article
  • Open Access
6 Citations
1,755 Views
19 Pages

Genomic Prediction and Genome-Wide Association Study for Growth-Related Traits in Taiwan Country Chicken

  • Tsung-Che Tu,
  • Chen-Jyuan Lin,
  • Ming-Che Liu,
  • Zhi-Ting Hsu and
  • Chih-Feng Chen

28 January 2025

Taiwan Country chickens are integral to Taiwanese culture and the poultry industry. By establishing a crossbreeding system, breeders must consider the growth-related traits of the dam line to achieve acceptable traits in commercial meat-type chickens...

  • Article
  • Open Access
1 Citations
1,633 Views
26 Pages

Pleiotropic Genes Affecting Milk Production, Fertility, and Health in Thai-Holstein Crossbred Dairy Cattle: A GWAS Approach

  • Akhmad Fathoni,
  • Wuttigrai Boonkum,
  • Vibuntita Chankitisakul,
  • Sayan Buaban and
  • Monchai Duangjinda

2 May 2025

Understanding the genetic basis of economically important traits is essential for enhancing the productivity, fertility, and health of dairy cattle. This study aimed to identify the pleiotropic genes associated with the 305-day milk yield (MY305), da...

  • Article
  • Open Access
1,465 Views
16 Pages

Ten Candidate Genes Were Identified to Be Associated with the Great Growth Differentiation in the Three-Way Cross Hybrid Abalone

  • Qizhen Xiao,
  • Shihai Gong,
  • Zekun Huang,
  • Wenzhu Peng,
  • Zhaofang Han,
  • Yang Gan,
  • Yawei Shen,
  • Weiwei You,
  • Caihuan Ke and
  • Xuan Luo

14 January 2025

Abalone is an economically important mollusk, whose slow growth has impeded the recovery of its wild populations and development of aquaculture. The three-way cross hybrid abalone ((Haliotis discus hannai♀ × H. fulgens♂)♀ &tim...

  • Article
  • Open Access
2 Citations
1,930 Views
17 Pages

27 December 2024

Days open (DO) is a critical economic and reproductive trait that is commonly employed in genetic selection. Making improvements using conventional genetic techniques is exceedingly challenging. Therefore, new techniques are required to improve the a...

  • Article
  • Open Access
4 Citations
2,891 Views
14 Pages

Background: Gut microbiota have been previously reported to be related to a variety of immune diseases. However, the causal connection between Sjögren’s syndrome (SS) and gut microbiota has yet to be clarified. Methods: We employed a two-s...

  • Article
  • Open Access
16 Citations
6,176 Views
14 Pages

24 December 2020

Red raspberry (Rubus idaeus L.) is an expanding high-value berry crop worldwide. The presence of prickles, outgrowths of epidermal tissues lacking vasculature, on the canes, petioles, and undersides of leaves complicates both field management and har...

  • Article
  • Open Access
25 Citations
4,814 Views
21 Pages

Genome-Wide Association Study Reveals Genomic Regions Associated with Fusarium Wilt Resistance in Common Bean

  • Jean Fausto de Carvalho Paulino,
  • Caléo Panhoca de Almeida,
  • César Júnior Bueno,
  • Qijian Song,
  • Roberto Fritsche-Neto,
  • Sérgio Augusto Morais Carbonell,
  • Alisson Fernando Chiorato and
  • Luciana Lasry Benchimol-Reis

18 May 2021

Fusarium wilt (Fusarium oxysporum f. sp. phaseoli, Fop) is one of the main fungal soil diseases in common bean. The aim of the present study was to identify genomic regions associated with Fop resistance through genome-wide association studies (GWAS)...

  • Article
  • Open Access
10 Citations
3,914 Views
18 Pages

Genome-Wide Association Mapping for Yield and Yield-Related Traits in Rice (Oryza Sativa L.) Using SNPs Markers

  • Muhammad Ashfaq,
  • Abdul Rasheed,
  • Renshan Zhu,
  • Muhammad Ali,
  • Muhammad Arshad Javed,
  • Alia Anwar,
  • Javaria Tabassum,
  • Shabnum Shaheen and
  • Xianting Wu

15 May 2023

Rice (Oryza sativa L.) is a staple food for more than 50% of the world’s population. Rice cultivar improvement is critical in order to feed the world’s growing population. Improving yield is one of the main aims of rice breeders. However,...

  • Article
  • Open Access
1 Citations
1,555 Views
17 Pages

Novel Metabolites Genetically Linked to Salt Sensitivity of Blood Pressure: Evidence from mGWAS in Chinese Population

  • Xiaojun Yang,
  • Bowen Zhang,
  • Fuyuan Wen,
  • Han Qi,
  • Fengxu Zhang,
  • Yunyi Xie,
  • Wenjuan Peng,
  • Boya Li,
  • Aibin Qu and
  • Ling Zhang
  • + 1 author

This study aims to identify genetically influenced metabolites (GIMs) associated with SSBP and elucidate their regulatory pathways through metabolome genome-wide association studies (mGWASs). Untargeted metabolomics and genome-wide genotyping were pe...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,092 Views
18 Pages

Weighted Single-Step GWAS Reveals Genomic Regions Associated with Female Fertility in the Spanish Retinta Beef Cattle

  • Rosa María Morales,
  • Gabriel Anaya Calvo-Rubio,
  • Chiraz Ziadi,
  • María Ángeles Vargas-Pérez,
  • Sebastián Demyda-Peyrás and
  • Antonio Molina

11 September 2025

Improving reproductive efficiency in beef cattle remains a key objective for sustainable genetic progress, particularly in extensively managed autochthonous breeds such as the Spanish Retinta. In this study, we applied a weighted single-step genome-w...

  • Article
  • Open Access
2 Citations
1,763 Views
15 Pages

Pangenome-Wide Association Study in the Chlamydiaceae Family Reveals Key Evolutionary Aspects of Their Relationship with Their Hosts

  • Rosalba Salgado-Morales,
  • Karla Barba-Xochipa,
  • Fernando Martínez-Ocampo,
  • Edgar Dantán-González,
  • Armando Hernández-Mendoza,
  • Manuel Quiterio-Trenado,
  • Magdalena Rodríguez-Santiago and
  • Abraham Rivera-Ramírez

26 November 2024

The Chlamydiaceae are a family of obligate intracellular bacteria known for their unique biphasic developmental cycle. Chlamydial are associated with various host organisms, including humans, and have been proposed as emerging pathogens. Genomic stud...

  • Article
  • Open Access
10 Citations
3,766 Views
28 Pages

Genome-Wide Association (GWAS) Applied to Carcass and Meat Traits of Nellore Cattle

  • Hugo Borges Dos Reis,
  • Minos Esperândio Carvalho,
  • Rafael Espigolan,
  • Mirele Daiana Poleti,
  • Dewison Ricardo Ambrizi,
  • Mariana Piatto Berton,
  • José Bento Sterman Ferraz,
  • Elisângela Chicaroni de Mattos Oliveira and
  • Joanir Pereira Eler

21 December 2023

The meat market has enormous importance for the world economy, and the quality of the product offered to the consumer is fundamental for the success of the sector. In this study, we analyzed a database which contained information on 2470 animals from...

  • Article
  • Open Access
9 Citations
4,640 Views
14 Pages

5 February 2022

The purpose of this study was to perform a genome-wide association study to determine the genomic regions associated with heat stress tolerance in swine. Phenotypic information on carcass weight was available for 227,043 individuals from commercial f...

  • Article
  • Open Access
3 Citations
1,221 Views
17 Pages

Identification of Loci and Candidate Genes Associated with Arginine Content in Soybean

  • Jiahao Ma,
  • Qing Yang,
  • Cuihong Yu,
  • Zhi Liu,
  • Xiaolei Shi,
  • Xintong Wu,
  • Rongqing Xu,
  • Pengshuo Shen,
  • Yuechen Zhang and
  • Long Yan
  • + 1 author

30 May 2025

Soybean (Glycine max) seeds are rich in amino acids, offering key nutritional and physiological benefits. In this study, 290 soybean accessions from the USDA Germplasm Collection based in Urbana, IL Information Network (GRIN) were analyzed. Four Geno...

  • Article
  • Open Access
5 Citations
3,574 Views
15 Pages

Identification of Genetic Markers for the Detection of Bacillus thuringiensis Strains of Interest for Food Safety

  • Arnaud Fichant,
  • Arnaud Felten,
  • Armel Gallet,
  • Olivier Firmesse and
  • Mathilde Bonis

5 December 2022

Bacillus thuringiensis (Bt), belonging to the Bacillus cereus (Bc) group, is commonly used as a biopesticide worldwide due to its ability to produce insecticidal crystals during sporulation. The use of Bt, especially subspecies aizawai and kurstaki,...

  • Article
  • Open Access
103 Views
22 Pages

Characterization of Genetic Diversity and Genomic Prediction of Secondary Metabolites in Pea Genetic Resources

  • Stefano Zanotto,
  • Nelson Nazzicari,
  • Gesine Schmidt,
  • Ulrike Böcker,
  • Francesca Vurro,
  • Antonella Pasqualone,
  • Anne Kjersti Uhlen and
  • Paolo Annicchiarico

23 January 2026

This study aimed to assess the variation, genetic architecture, and genome-enabled prediction of traits with nutritional and health relevance in 156 pea (Pisum sativum L.) accessions of diverse geographic origins. The traits included the total phenol...

  • Article
  • Open Access
21 Citations
4,519 Views
20 Pages

Genome-Wide Association Mapping for Stomata and Yield Indices in Bread Wheat under Water Limited Conditions

  • Hafiz Ghulam Muhu-Din Ahmed,
  • Muhammad Nouman Iqbal,
  • Muhammad Arslan Iqbal,
  • Yawen Zeng,
  • Aziz Ullah,
  • Muhammad Iqbal,
  • Humayun Raza,
  • Muhammad Majid Yar,
  • Nadeem Sarwar and
  • Saddam Hussain
  • + 1 author

18 August 2021

Genome-wide association study (GWAS) was performed for stomata- and yield-related attributes with high-density Illumina 90 K Infinium SNP (single nucleotide polymorphism) array in bread wheat to determine genetic potential of germplasm for scarce wat...

  • Article
  • Open Access
3 Citations
3,900 Views
20 Pages

Accurate Phenotypic Identification and Genetic Analysis of the Ear Leaf Veins in Maize (Zea mays L.)

  • Shangjing Guo,
  • Mingyi Zhu,
  • Jianjun Du,
  • Jinglu Wang,
  • Xianju Lu,
  • Yu Jin,
  • Minggang Zhang,
  • Xinyu Guo and
  • Ying Zhang

4 March 2023

The ear leaf veins are an important transport structure in the maize "source" organ; therefore, the microscopic phenotypic characteristics and genetic analysis of the leaf veins are particularly essential for promoting the breeding of ideal maize var...

  • Article
  • Open Access
7 Citations
4,016 Views
14 Pages

Determination of Genetic Effects of LIPK and LIPJ Genes on Milk Fatty Acids in Dairy Cattle

  • Lijun Shi,
  • Bo Han,
  • Lin Liu,
  • Xiaoqing Lv,
  • Zhu Ma,
  • Cong Li,
  • Lingna Xu,
  • Yanhua Li,
  • Feng Zhao and
  • Dongxiao Sun
  • + 1 author

28 January 2019

In our previous genome-wide association study (GWAS) on milk fatty acids (FAs) in Chinese Holstein, we discovered 83 genome-wide significant single nucleotide polymorphisms (SNPs) associated with milk FAs. Two of them were close to lipase family memb...

  • Review
  • Open Access
76 Citations
13,375 Views
21 Pages

Genomic Analysis, Progress and Future Perspectives in Dairy Cattle Selection: A Review

  • Miguel A. Gutierrez-Reinoso,
  • Pedro M. Aponte and
  • Manuel Garcia-Herreros

25 February 2021

Genomics comprises a set of current and valuable technologies implemented as selection tools in dairy cattle commercial breeding programs. The intensive progeny testing for production and reproductive traits based on genomic breeding values (GEBVs) h...