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1,322 Results Found

  • Article
  • Open Access
3 Citations
2,699 Views
14 Pages

A Real-World Data Derived Pharmacovigilance Assessment on Drug-Induced Nephropathy: Implication on Gaps in Patient Care

  • Yujin Kim,
  • Chang-Young Choi,
  • Yongjun Sunwoo,
  • Chaerin Go,
  • Semi Kim,
  • Sae Hyun Eom,
  • Sooyoung Shin and
  • Yeo Jin Choi

31 December 2023

This retrospective cross-sectional study aims to investigate the prevalence and seriousness of drug-induced nephrotoxicity and to identify clinical predictors intensifying the seriousness of nephrotoxicity. Adverse drug events (ADEs) reported to the...

  • Review
  • Open Access
4,275 Views
21 Pages

Addressing Patient–Provider Communication Gaps in Vanishing Twin Syndrome: Implications for Patient Care and Clinical Guidelines

  • Nichole M. Cubbage,
  • Samantha L. P. Schilit,
  • Allison Groff,
  • Stephanie Ernst and
  • Marc A. Nascarella

19 August 2025

Background: Vanishing twin syndrome (VTS) represents a complex and under-recognized phenomenon in multifetal pregnancies, associated with both clinical uncertainty and significant psychosocial impact. Despite its frequency, gaps remain in diagnostic...

  • Review
  • Open Access
20 Citations
7,529 Views
14 Pages

Gaps and Interventions across the Diagnostic Care Cascade of TB Patients at the Level of Patient, Community and Health System: A Qualitative Review of the Literature

  • Harsh D Shah,
  • Mahalaqua Nazli Khatib,
  • Zahiruddin Quazi Syed,
  • Abhay M. Gaidhane,
  • Sandul Yasobant,
  • Kiran Narkhede,
  • Priya Bhavsar,
  • Jay Patel,
  • Anish Sinha and
  • Deepak Saxena
  • + 2 authors

Tuberculosis (TB) continues to be one of the important public health concerns globally, and India is among the seven countries with the largest burden of TB. There has been a consistent increase in the notifications of TB cases across the globe. Howe...

  • Article
  • Open Access
37 Citations
10,043 Views
10 Pages

Measuring Quality Gaps in TB Screening in South Africa Using Standardised Patient Analysis

  • Carmen S. Christian,
  • Ulf-G. Gerdtham,
  • Dumisani Hompashe,
  • Anja Smith and
  • Ronelle Burger

This is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at t...

  • Review
  • Open Access
5 Citations
2,931 Views
19 Pages

Enhancing Lung Cancer Care in Portugal: Bridging Gaps for Improved Patient Outcomes

  • Raquel Ramos,
  • Conceição Souto Moura,
  • Mariana Costa,
  • Nuno Jorge Lamas,
  • Renato Correia,
  • Diogo Garcez,
  • José Miguel Pereira,
  • Carlos Sousa and
  • Nuno Vale

24 April 2024

Lung cancer has the highest incidence and cancer-related mortality worldwide. In Portugal, it ranks as the fourth most common cancer, with nearly 6000 new cases being diagnosed every year. Lung cancer is the main cause of cancer-related death among m...

  • Article
  • Open Access
3 Citations
1,831 Views
16 Pages

Perceived Gaps in Oncologic Emergency Care for Patients with Cancer: A Qualitative Comparison of Emergency Medicine and Oncologist Physician Perspectives

  • Monica K. Wattana,
  • Moira Davenport,
  • Jason J. Bischof,
  • Angela B. Lindsay,
  • Nicholas R. Pettit,
  • Jazmin R. Menendez,
  • Kelsey Harper,
  • Demis N. Lipe and
  • Aiham Qdaisat

27 February 2025

Objective: Providing high-quality, safe, and consistent care for patients with cancer in the emergency department (ED) poses unique challenges. To better understand these challenges, we surveyed oncologists and emergency medicine (EM) physicians acro...

  • Article
  • Open Access
1,370 Views
13 Pages

Background/Objectives: Adults with type 1 diabetes (T1D) experience disproportionately high rates of depression, anxiety, and psychological distress, yet integration of behavioral health into diabetes care remains limited. The objective of this study...

  • Article
  • Open Access
2 Citations
1,055 Views
13 Pages

Objective: This study aimed to quantify the discrepancy between perceived and ideal sleep duration among primary care patients and identify demographic, lifestyle, and psychological factors associated with this expectation–reality gap. Methods:...

  • Article
  • Open Access
2 Citations
3,216 Views
17 Pages

Improving Practice for Urinary Continence Care on Adult Acute Medical and Rehabilitation Wards: A Multi-Site, Co-Created Implementation Study

  • Dianne Lesley Marsden,
  • Kerry Boyle,
  • Jaclyn Birnie,
  • Amanda Buzio,
  • Joshua Dizon,
  • Judith Dunne,
  • Sandra Greensill,
  • Kelvin Hill,
  • Sandra Lever and
  • Jed Duff
  • + 7 authors

Many adult inpatients experience urinary continence issues; however, we lack evidence on effective interventions for inpatient continence care. We conducted a before and after implementation study. We implemented our guideline-based intervention usin...

  • Article
  • Open Access
3 Citations
3,822 Views
11 Pages

Changes to the payment structure of the United States (U.S.) healthcare system are leading to an increased acuity level of patients receiving short-term skilled nursing facility care. Most skilled nursing facility patients are older, and many have me...

  • Article
  • Open Access
2 Citations
2,874 Views
18 Pages

Persistent Cardiometabolic Health Gaps: Can Therapeutic Care Gaps Be Precisely Identified from Electronic Health Records

  • Xiaowei Yan,
  • Walter F. Stewart,
  • Hannah Husby,
  • Jake Delatorre-Reimer,
  • Satish Mudiganti,
  • Farah Refai,
  • Andrew Hudnut,
  • Kevin Knobel,
  • Karen MacDonald and
  • James B. Jones
  • + 1 author

31 December 2021

The objective of this study was to determine the strengths and limitations of using structured electronic health records (EHR) to identify and manage cardiometabolic (CM) health gaps. We used medication adherence measures derived from dispense data t...

  • Article
  • Open Access
2 Citations
2,876 Views
10 Pages

Pancreatic Adenocarcinoma: Real World Evidence of Care Delivery in AccessHope Data

  • Afsaneh Barzi,
  • Angela J. Kim,
  • Crystal K. Liang,
  • Howard West,
  • D. Wong,
  • Carol Wright,
  • Nitya Nathwani,
  • Catherine M. Vasko,
  • Vincent Chung and
  • Todd Sachs
  • + 1 author

15 September 2023

Background: Pancreatic adenocarcinoma is an aggressive disease and the delivery of comprehensive care to individuals with this cancer is critical to achieve appropriate outcomes. The identification of gaps in care delivery facilitates the design of i...

  • Article
  • Open Access
1 Citations
3,014 Views
9 Pages

Variable Creatinine Levels in Critical Care Patients: A Concerning Knowledge Gap

  • Trushil Shah,
  • Madhusudhanan Narasimhan,
  • Mary Latha Rathinam,
  • Karen Relle,
  • Melanie Kim,
  • Tharani Muthukumar,
  • William Tharpe,
  • Sonja Bartolome,
  • Lenin Mahimainathan and
  • Alagarraju Muthukumar

15 April 2021

An accurate creatinine (Cr) estimate is pivotal for the assessment of renal function. Both patient- and practice-spawned factors palliate the test accuracy of serum creatinine (sCr) and can erratically represent actual kidney function. This study eva...

  • Article
  • Open Access
4 Citations
2,866 Views
14 Pages

Perceived Provision of Perioperative Information and Care by Patients Who Have Undergone Surgery for Colorectal Cancer: A Cross-Sectional Study

  • Alison Zucca,
  • Elise Mansfield,
  • Rob Sanson-Fisher,
  • Rebecca Wyse,
  • Sally-Anne Johnston,
  • Kristy Fakes,
  • Sancha Robinson and
  • Stephen Smith

Background: Active patient participation in preparation and recovery from colorectal cancer surgery can be facilitated by timely information and care and may improve patient wellbeing and reduce hospitalizations; Methods: We aimed to identify gaps in...

  • Article
  • Open Access
2,488 Views
16 Pages

Background: Continuity of care is critical for optimal stroke rehabilitation, yet gaps in post-stroke services in Saudi Arabia may undermine long-term patient outcomes and recovery. The therapists who care for people with stroke should be aware of pa...

  • Article
  • Open Access
2 Citations
2,713 Views
8 Pages

Background: An increasing number of patients included in home mechanical ventilation (HMV) care has been under observation for many years. The study aimed to assess the patients opinion concerning the expected and perceived quality of care in an HMV...

  • Article
  • Open Access
7 Citations
3,223 Views
11 Pages

Challenges for Latina Breast Cancer Patient Survivorship Care in a Rural US-Mexico Border Region

  • Eunjeong Ko,
  • Veronica Cardenas,
  • María Luisa Zúñiga,
  • Susan I. Woodruff,
  • Viviane Rodriguez and
  • Helen Palomino

Rural US Latina breast cancer patients experience language barriers, health literacy issues, and limited access to health care resources that negatively impact survivorship care. This study explored the challenges to survivorship care for rural Latin...

  • Article
  • Open Access
15 Citations
5,719 Views
18 Pages

Examining the Gaps and Issues of End-of-Life Care among Older Population through the Lens of Socioecological Model—A Multi-Method Qualitative Study of Hong Kong

  • Roger Yat-Nork Chung,
  • Dong Dong,
  • Nancy Nam Sze Chau,
  • Patsy Yuen-Kwan Chau,
  • Eng Kiong Yeoh and
  • Eliza Lai-Yi Wong

End-of-life (EOL) care for terminal illness and life-limiting conditions is a sector in the health service spectrum that is drawing increased attention. Despite having the world’s longest life expectancy and an ever-escalating demand for long-t...

  • Article
  • Open Access
14 Citations
4,875 Views
21 Pages

Hemodynamic Insights into Abdominal Aortic Aneurysms: Bridging the Knowledge Gap for Improved Patient Care

  • Suvash C. Saha,
  • Isabella Francis,
  • Goutam Saha,
  • Xinlei Huang and
  • Md. Mamun Molla

15 February 2024

Background: Abdominal aortic aneurysms (AAAs) present a formidable public health concern due to their propensity for localized, anomalous expansion of the abdominal aorta. These insidious dilations, often in their early stages, mask the life-threaten...

  • Article
  • Open Access
5 Citations
2,782 Views
15 Pages

Are Energy and Protein Intakes Lower Than Requirements in Older Adults? An Urgent Issue in Hospitals and Nursing Homes

  • Marie Blanquet,
  • Candy Guiguet-Auclair,
  • Pauline Berland,
  • Guillaume Ducher,
  • Anaïs Sauvage,
  • Sylvain Dadet,
  • Vincent Guiyedi,
  • Nicolas Farigon,
  • Jérôme Bohatier and
  • Yves Boirie
  • + 1 author

26 July 2023

Energy and protein intakes lower than requirements are associated with worsening health outcomes. Here we set out to evaluate gaps between energy and protein intakes and requirements in older adults in hospitals and in nursing homes (NH). A cross-sec...

  • Article
  • Open Access
4 Citations
4,966 Views
14 Pages

Restructuring Skin Cancer Care in Ontario: A Provincial Plan

  • John Milkovich,
  • Tim Hanna,
  • Carolyn Nessim,
  • Teresa M. Petrella,
  • Louis Weatherhead,
  • An-Wen Chan,
  • Jonathan C. Irish,
  • Christian Murray,
  • Grace Bannerman and
  • the Ontario Skin Cancer Advisory Committee
  • + 4 authors

12 March 2021

There is a global rise in skin cancer incidence, resulting in an increase in patient care needs and healthcare costs. To optimize health care planning, costs, and patient care, Ontario Health developed a provincial skin cancer plan to streamline the...

  • Article
  • Open Access
9 Citations
4,771 Views
13 Pages

16 April 2022

Introduction: There is a gap in healthcare literature related to the spiritual competence of physicians and nurses practicing in South Asian Muslim communities. To fill that gap, the Spiritual Care Competence Questionnaire (SCCQ) was applied which wa...

  • Article
  • Open Access
1,066 Views
16 Pages

Quality of Care for Hypertension in Primary Health Care in South Africa: Cross-Sectional Feasibility Study

  • Enos Muisaphanda Rampamba,
  • Stephen M. Campbell,
  • Brian Godman and
  • Johanna C. Meyer

24 September 2025

Introduction: Little is known about the quality of care for patients with hypertension in primary health care (PHC) facilities in South Africa, where most people receive care. Objectives: To test 46 quality indicators, developed previously, to assess...

  • Case Report
  • Open Access
1 Citations
2,291 Views
10 Pages

24 October 2023

When accessing medical care, lesbian, gay, bisexual, transgender, queer/questioning plus (LGBTQ+) individuals face many known challenges, including stigma, discrimination, and health disparities. Transgender and nonbinary individuals often encounter...

  • Article
  • Open Access
17 Citations
4,357 Views
17 Pages

Translating Evidence-Based Guidelines into Practice—Are We Getting It Right? A Multi-Centre Prospective International Audit of Nutrition Care in Patients with Foregut Tumors (INFORM)

  • Merran Findlay,
  • Judith D. Bauer,
  • Rupinder Dhaliwal,
  • Marian de van der Schueren,
  • Alessandro Laviano,
  • Adrianne Widaman,
  • Lisa Martin,
  • Andrew G. Day and
  • Leah M. Gramlich

11 December 2020

Malnutrition is highly prevalent in patients with foregut tumors comprising head and neck (HNC) and esophageal (EC) cancers, negatively impacting outcomes. International evidence-based guidelines (EBGs) for nutrition care exist; however, translation...

  • Review
  • Open Access
1,140 Views
9 Pages

Bringing Clarity to Complex Pediatric Perioperative Care: Development of a Novel Pathway to Support Goal-Directed, Patient-Centered Care

  • Tiffany Lin,
  • Neveada Raventhiranathan,
  • Myra Ahmad,
  • Andrew L. Feit,
  • Allison E. Hotze,
  • Grace L. Ker,
  • Robert P. Moore and
  • Sergio D. Bergese

26 April 2025

Background: Advances in pediatric perioperative care have supported the safe provision of increasingly complex surgical care to patients with complicated diseases and abnormal physiology. This has led to the possible misalignment of the impact of pot...

  • Article
  • Open Access
888 Views
10 Pages

10 July 2025

Background/Objectives: The pediatric mental health crisis in the United States has reached unprecedented levels. Severe shortages in specialized health care professionals, particularly child and adolescent psychiatrists (CAPs), exacerbate the challen...

  • Article
  • Open Access
1,153 Views
20 Pages

Collaborative Funding Model to Improve Quality of Care for Metastatic Breast Cancer in Europe

  • Matti S. Aapro,
  • Jacqueline Waldrop,
  • Oriana Ciani,
  • Amanda Drury,
  • Theresa Wiseman,
  • Marianna Masiero,
  • Joanna Matuszewska,
  • Shani Paluch-Shimon,
  • Gabriella Pravettoni and
  • Nicola Fenderico
  • + 5 authors

30 September 2025

Breast cancer (BC) is the most frequently diagnosed malignancy in women. Currently, BC is treated with a holistic and multidisciplinary approach from diagnostic, surgical, radio-oncological, and medical perspectives, and advances including in early d...

  • Communication
  • Open Access
67 Citations
9,765 Views
14 Pages

The overarching goal of care coordination is communication and co-management across settings. Children with medical complexity require care from multiple services and providers, and the many benefits of care coordination on health and patient experie...

  • Review
  • Open Access
20 Citations
5,897 Views
10 Pages

Palliative care is indicated in patients with heart failure since the early phases of the disease, as suggested by international guidelines. However, patients are referred to palliative care very late. Many barriers could explain the gap between the...

  • Article
  • Open Access
7 Citations
4,835 Views
14 Pages

Although the progressive clinical trajectory of motor neurone disease (MND) is widely understood, multiple challenges remain preventing optimal end-of-life care for this population with unique needs from the patient, carer and service provider perspe...

  • Article
  • Open Access
14 Citations
4,697 Views
12 Pages

Healthcare Professional Students’ Perspectives on Substance Use Disorders and Stigma: A Qualitative Study

  • Alina Cernasev,
  • Kiki M. Kline,
  • Rachel Elizabeth Barenie,
  • Kenneth C. Hohmeier,
  • Steven Stewart and
  • Shandra S. Forrest-Bank

Background: Access to and quality of care for Substance Use Disorders (SUDs) remain a major public health issue. Stigma associated with SUDs contributes to the gap between the number of patients who need treatment and the much smaller fraction that r...

  • Article
  • Open Access
21 Citations
1,462 Views
10 Pages

Cross-Disciplinary Research in Cancer: An Opportunity to Narrow the Knowledge–Practice Gap

  • R. Urquhart,
  • E. Grunfeld,
  • L. Jackson,
  • J. Sargeant and
  • G.A. Porter

1 December 2013

Health services researchers have consistently identified a gap between what is identified as “best practice” and what actually happens in clinical care. Despite nearly two decades of a growing evidence-based practice movement, narrowing the knowledge...

  • Opinion
  • Open Access
6 Citations
5,270 Views
11 Pages

Nutrition is a foundation of health and one of six pillars of Lifestyle Medicine. The importance of nutrition in clinical care is now widely recognized by health care professionals and the public. However, clinicians are not comfortable counselling t...

  • Review
  • Open Access
3 Citations
2,743 Views
11 Pages

Quality Measures in Systemic Sclerosis

  • Aos Aboabat,
  • Zareen Ahmad,
  • Amanda Steiman and
  • Sindhu R. Johnson

Quality improvement is an emerging field, that applies principles of improvement science and utilizes measurement methods with the aim of improving patient care. Systemic sclerosis (SSc) is a systemic autoimmune rheumatic disease associated with incr...

  • Review
  • Open Access
13 Citations
5,072 Views
8 Pages

7 August 2018

Chronic obstructive pulmonary disease (COPD) is the second leading cause of emergency department (ED) admissions to hospital, and nearly a third of patients with acute exacerbation (AE) of COPD are re-admitted to hospital within 28 days after dischar...

  • Article
  • Open Access
10 Citations
1 Views
5 Pages

The Cost of Implementing a Nationwide Program to Decrease the Epilepsy Treatment Gap in a High Gap Country

  • Gretchen L. Birbeck,
  • Elwyn Chomba,
  • Edward Mbewe,
  • Masharip Atadzhanov,
  • Alan Haworth and
  • Henry Kansembe

5 October 2012

Healthcare systems in many low income countries have evolved to provide services for acute, infections and are poorly structured for the provision of chronic, non-communicable diseases which are increasingly common. Epilepsy is a common chronic neuro...

  • Review
  • Open Access
5 Citations
5,555 Views
16 Pages

23 February 2024

Lung cancer treatment and patient care are constantly improving, but it remains doubtful whether this applies equally to all socioeconomic groups. It is nowadays well established that there are socioeconomic inequalities regarding lung cancer inciden...

  • Perspective
  • Open Access
21 Citations
20,498 Views
12 Pages

Caring for the Patient with Severe or Very Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

  • Jose G. Montoya,
  • Theresa G. Dowell,
  • Amy E. Mooney,
  • Mary E. Dimmock and
  • Lily Chu

6 October 2021

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can cause a wide range of severity and functional impairment, leaving some patients able to work while others are homebound or bedbound. The most severely ill patients may need total care. Y...

  • Review
  • Open Access
24 Citations
8,117 Views
17 Pages

19 February 2019

In the last few years, important changes have occurred in the clinical and epidemiological characteristics of patients that were admitted to cardiac intensive care units (CICU). Care has shifted from acute coronary syndrome patients towards elderly p...

  • Review
  • Open Access
1 Citations
9,396 Views
33 Pages

The Future of Cardiothoracic Surgical Critical Care Medicine as a Medical Science: A Call to Action

  • Rafal Kopanczyk,
  • Jesse Lester,
  • Micah T. Long,
  • Briana J. Kossbiel,
  • Aaron S. Hess,
  • Alan Rozycki,
  • David R. Nunley,
  • Alim Habib,
  • Ashley Taylor and
  • Amar M. Bhatt
  • + 1 author

27 December 2022

Cardiothoracic surgical critical care medicine (CT-CCM) is a medical discipline centered on the perioperative care of diverse groups of patients. With an aging demographic and an increase in burden of chronic diseases the utilization of cardiothoraci...

  • Article
  • Open Access
9 Citations
2,195 Views
10 Pages

“No One Truly Understands What We Go through and How to Treat It”: Lived Experiences with Medical Providers among Patients with Orofacial Pain

  • Victoria A. Grunberg,
  • Mira Reichman,
  • Brenda C. Lovette,
  • Ana-Maria Vranceanu and
  • Jonathan Greenberg

Orofacial pain affects 10–15% of adults, yet treatments are limited. The gaps in care are frustrating for both patients and providers and can negatively impact patient–provider interactions. These interactions are key because they impact...

  • Article
  • Open Access
929 Views
10 Pages

20 October 2025

Systemic Lupus Erythematosus (SLE) is a multifaceted autoimmune disease that requires individualized care and informed patient counseling. Pharmacists are well-positioned to support SLE patients, yet gaps in knowledge and preparedness among pharmacy...

  • Article
  • Open Access
17 Citations
6,122 Views
14 Pages

Exploring the Relationship between Window View Quantity, Quality, and Ratings of Care in the Hospital

  • Sahar Mihandoust,
  • Anjali Joseph,
  • Sara Kennedy,
  • Piers MacNaughton and
  • May Woo

Hospital ratings reflect patient satisfaction, consumer perception of care, and create the context for quality improvement in healthcare settings. Despite an abundance of studies on the health benefits of the presence and content of window views, the...

  • Article
  • Open Access
1,093 Views
16 Pages

Facilitating and Hindering Factors in the Implementation of a Care Transition Strategy: Mixed Methods Study

  • Marcia Baiocchi Amaral Danielle,
  • Elisiane Lorenzini,
  • Ana Letícia Missio de Oliveira,
  • Anthony John Onwuegbuzie,
  • Letícia Flores Trindade,
  • Michelle Mariah Malkiewiez,
  • Darlisom Sousa Ferreira,
  • Luana Amaral Alpirez and
  • Adriane Cristina Bernat Kolankiewicz

Objective: To identify facilitating and hindering factors for implementing a care transition strategy for adult patients undergoing elective colorectal cancer surgery, within a primary health care (PHC) context, addressing gaps in the literature on i...

  • Review
  • Open Access
14 Citations
3,241 Views
16 Pages

Patient Preferences in Metastatic Breast Cancer Care: A Scoping Review

  • Kelcey A. Bland,
  • Reem Mustafa and
  • Helen McTaggart-Cowan

30 August 2023

People with metastatic breast cancer (MBC) have diverse medical, physical, and psychosocial needs that require multidimensional care. Understanding patient preferences is crucial to tailor treatments, services, and foster patient-centered care. A sco...

  • Article
  • Open Access
34 Citations
33,695 Views
25 Pages

The healthcare industry has recently faced the issues of enhancing patient care, streamlining healthcare operations, and offering high-quality services at reasonable costs. These crucial issues include general healthcare administration, resource allo...

  • Review
  • Open Access
14 Citations
4,596 Views
10 Pages

Pre-exposure prophylaxis (PrEP) for the human immunodeficiency virus (HIV) is rapidly increasing in use worldwide, with many countries now publicly funding use for high risk populations. Pharmacists, as front-line care providers, must have the necess...

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