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20 Results Found

  • Review
  • Open Access
14 Citations
4,667 Views
25 Pages

28 September 2022

This review presents literature data: the history of the discovery of quinoid compounds, their biosynthesis and biological activity. Special attention is paid to the description of the quinoid pigments of the sea urchins Scaphechinus mirabilis (from...

  • Article
  • Open Access
4 Citations
3,324 Views
9 Pages

Determination of the Qualitative Composition of Biologically Active Substances of Extracts of In Vitro Callus, Cell Suspension, and Root Cultures of the Medicinal Plant Rhaponticum carthamoides

  • Lyudmila Asyakina,
  • Svetlana Ivanova,
  • Alexander Prosekov,
  • Lyubov Dyshlyuk,
  • Evgeny Chupakhin,
  • Elena Ulrikh,
  • Olga Babich and
  • Stanislav Sukhikh

12 March 2021

This work aims to study the qualitative composition of biologically active substance (BAS) extracts in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides. The research methodology is based on high-perform...

  • Article
  • Open Access
9 Citations
3,386 Views
13 Pages

One-Step Synthesis of Magnetic Nanocomposite with Embedded Biologically Active Substance

  • Zhanna Ignatovich,
  • Khristina Novik,
  • Anna Abakshonok,
  • Elena Koroleva,
  • Anna Beklemisheva,
  • Larisa Panina,
  • Egor Kaniukov,
  • Marina Anisovich and
  • Alena Shumskaya

10 February 2021

Magnetic nanocomposites based on hydroxyapatite were prepared by a one-step process using the hydrothermal coprecipitation method to sinter iron oxides (Fe3O4 and γ-Fe2O3). The possibility of expanding the proposed technique for the synthesis of magn...

  • Article
  • Open Access
898 Views
17 Pages

Design of Composite Systems Based on Hydrophilic Silica and Organic Acids: Gallic, Glycyrrhizic and Its Salts

  • Tetiana Krupska,
  • Qiliang Wei,
  • Jinju Zheng,
  • Weiyou Yang,
  • Alina Holovan,
  • Mykola Borysenko and
  • Volodymyr Turov

The process of formation of composite systems based on nanosilica A-300 and biologically active substances (BAS), namely gallic acid (GA), glycyrrhizic acid (GLA), and its salts, was studied using a set of physicochemical methods. It was shown that w...

  • Article
  • Open Access
11 Citations
3,635 Views
14 Pages

27 February 2021

The results of the qualitative composition analysis of the dried biomass extracts of in vitro callus, cell suspension, and root cultures show that the main biologically active substances (BAS) in the medicinal plant, Rhodiola rosea, are 6-C-(1-(4-hyd...

  • Communication
  • Open Access
5 Citations
2,376 Views
11 Pages

Correlation between Biogenic Amines and Their Precursors in Stored Chicken Meat

  • Wojciech Wójcik,
  • Krzysztof Damaziak,
  • Monika Łukasiewicz-Mierzejewska,
  • Olga Świder,
  • Jan Niemiec,
  • Michał Wójcicki,
  • Marek Roszko,
  • Dariusz Gozdowski,
  • Julia Riedel and
  • Agata Marzec

10 November 2023

Biogenic amines (BAs) are biologically active substances found in the cells of microorganisms, plants, and animals. These BAs serve many vital functions in the body. However, an excessive amount can be toxic, especially for individuals taking monoami...

  • Article
  • Open Access
7 Citations
22,637 Views
14 Pages

Iota-Carrageenan Inhibits Replication of the SARS-CoV-2 Variants of Concern Omicron BA.1, BA.2 and BA.5

  • Christian Setz,
  • Maximilian Große,
  • Maria Fröba,
  • Janina Auth,
  • Pia Rauch,
  • Alexandra Herrmann,
  • Arne Cordsmeier,
  • Armin Ensser,
  • Michael Schindler and
  • Ulrich Schubert
  • + 4 authors

Even with its endemic transition, the COVID-19 pandemic remains a public health threat, particularly in the light of emerging variants of concern (VoCs) and the need for pandemic preparedness in the future. In November 2021, the SARS-CoV-2 VoC Omicro...

  • Article
  • Open Access
1 Citations
2,513 Views
18 Pages

Due to their richness in organic substances and nutrients, seaweed (macroalgae) harbor a large number of epiphytic bacteria on their surfaces. These bacteria interact with their host in multiple complex ways, in particular, by producing chemical comp...

  • Article
  • Open Access
8 Citations
3,461 Views
18 Pages

Environmentally safe ways are sought to prevent the accumulation and to accelerate the degradation of herbicide active substances in agricultural soil. This study aimed to determine the effectiveness of finely-ground barley straw and bentonite in mit...

  • Article
  • Open Access
15 Citations
3,277 Views
12 Pages

Heavy metals are unbreakable, and most of them are poisonous to animals and people. Metals are particularly concerning among environmental contaminants since they are less apparent, have extensive effects on ecosystems, are poisonous, and bioaccumula...

  • Abstract
  • Open Access
867 Views
1 Page

The aim of this study was to determine the nutritional composition and biologically active substances (BAS) of wild edible plants from Montenegro. Nettle (Urtica dioica L.) leaves, rosehips (Rosa canina L.), and the fruit of the strawberry tree (Arbu...

  • Article
  • Open Access
3 Citations
4,309 Views
14 Pages

Human Skin Fibroblasts as an In Vitro Model Illustrating Changes in Collagen Levels and Skin Cell Migration Under the Influence of Selected Plant Hormones

  • Agata Jabłońska-Trypuć,
  • Walentyn Pankiewicz,
  • Elżbieta Wołejko,
  • Gabriela Sokołowska,
  • Jorge Estévez,
  • Miguel A. Sogorb and
  • Urszula Wydro

Human skin fibroblasts are an excellent in vitro model for tracking the processes occurring in human skin and studying the potential impact of various biologically active substances on these processes. Two plant hormones, which are included in the cy...

  • Article
  • Open Access
10 Citations
2,080 Views
22 Pages

8 August 2023

This study aimed to investigate the anti-atherosclerotic properties of quercetin isolated from the extract of Hedysarum neglectum Ledeb hairy roots. During the study, the hormonal composition of the nutrient medium for cultivation of H. neglectum hai...

  • Article
  • Open Access
6 Citations
2,039 Views
21 Pages

Biochar, Halloysite, and Alginite Improve the Quality of Soil Contaminated with Petroleum Products

  • Jadwiga Wyszkowska,
  • Agata Borowik,
  • Magdalena Zaborowska and
  • Jan Kucharski

Investigations into the effective, fast, and economically viable remediation of soils polluted with petroleum-derived products are still relevant. The vegetative pot experiment was conducted at the Didactic-Experimental Garden greenhouse (NE, Poland,...

  • Review
  • Open Access
26 Citations
11,634 Views
20 Pages

Effects of Saponins on Lipid Metabolism: The Gut–Liver Axis Plays a Key Role

  • Shixi Cao,
  • Mengqi Liu,
  • Yao Han,
  • Shouren Li,
  • Xiaoyan Zhu,
  • Defeng Li,
  • Yinghua Shi and
  • Boshuai Liu

17 May 2024

Unhealthy lifestyles (high-fat diet, smoking, alcohol consumption, too little exercise, etc.) in the current society are prone to cause lipid metabolism disorders affecting the health of the organism and inducing the occurrence of diseases. Saponins,...

  • Review
  • Open Access
42 Citations
14,094 Views
51 Pages

Tackling Atherosclerosis via Selected Nutrition

  • Anna Vesnina,
  • Alexander Prosekov,
  • Victor Atuchin,
  • Varvara Minina and
  • Anastasia Ponasenko

The development and pathogenesis of atherosclerosis are significantly influenced by lifestyle, particularly nutrition. The modern level of science and technology development promote personalized nutrition as an efficient preventive measure against at...

  • Article
  • Open Access
501 Views
22 Pages

28 November 2025

Background: In Siberian folk medicine, Sagan-Dalya (Rhododendron adamsii Rehder) of the Ericaceae family is used as a tonic and restorative in the form of infusions and decoctions. Pharmacological studies have shown that alcoholic extracts of this pl...

  • Article
  • Open Access
1 Citations
2,281 Views
20 Pages

Combination of Betulinic Acid Fragments and Carbonic Anhydrase Inhibitors—A New Drug Targeting Approach

  • Matthias Bache,
  • Niels V. Heise,
  • Andreas Thiel,
  • Anne Funtan,
  • Franziska Seifert,
  • Marina Petrenko,
  • Antje Güttler,
  • Sarah Brandt,
  • Thomas Mueller and
  • Reinhard Paschke
  • + 2 authors

Human carbonic anhydrase IX (hCA IX) is a zinc(II)-dependent metalloenzyme that plays a critical role in the conversion of carbon dioxide and water to protons and bicarbonate. It is a membrane-bound protein with an extracellular catalytic center that...

  • Article
  • Open Access
10 Citations
5,029 Views
18 Pages

Broad Antiviral Effects of Echinacea purpurea against SARS-CoV-2 Variants of Concern and Potential Mechanism of Action

  • Selvarani Vimalanathan,
  • Mahmoud Shehata,
  • Kannan Sadasivam,
  • Serena Delbue,
  • Maria Dolci,
  • Elena Pariani,
  • Sarah D’Alessandro and
  • Stephan Pleschka

SARS-CoV-2 variants of concern (VOCs) represent an alarming threat as they show altered biological behavior and may escape vaccination effectiveness. Broad-spectrum antivirals could play an important role to control infections. The activity of Echina...

  • Article
  • Open Access
17 Citations
8,896 Views
19 Pages

The Role of Freeze-Drying as a Multifunctional Process in Improving the Properties of Hydrogels for Medical Use

  • Kacper Odziomek,
  • Anna K. Drabczyk,
  • Paulina Kościelniak,
  • Patryk Konieczny,
  • Mateusz Barczewski and
  • Katarzyna Bialik-Wąs

10 November 2024

Background/Objectives: Freeze-drying is a dehydration method that extends the shelf life and stability of drugs, vaccines, and biologics. Recently, its role has expanded beyond preservation to improve novel pharmaceuticals and their carriers, such as...