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40 Results Found

  • Article
  • Open Access
1 Citations
2,101 Views
11 Pages

Fractional CO2 Laser for Pediatric Hypertrophic Scars: Lessons Learned from a Prematurely Terminated Split-Scar Trial

  • Sarthak Sinha,
  • Altay Baykan,
  • Karen Hulin,
  • Doug Baron,
  • Vincent Gabriel and
  • Frankie O. G. Fraulin

20 February 2025

Background: Assessing hypertrophic scar (HTS) interventions is challenging because scars continue to undergo dynamic changes. A split-scar design can distinguish treatment effects from natural HTS evolution. Despite promising reports of ablative frac...

  • Article
  • Open Access
2 Citations
2,665 Views
12 Pages

Mid-Term Follow-Up Study of Children Undergoing Autologous Skin Transplantation for Burns

  • Angyalka Válik,
  • Katalin Harangozó,
  • András Garami,
  • Zsolt Juhász,
  • Gergő Józsa and
  • Aba Lőrincz

11 March 2023

Deep partial and full-thickness burns require surgical treatment with autologous skin grafts after necrectomy, which is the generally accepted way to achieve permanent wound coverage. This study sought to examine the grafted and donor areas of childr...

  • Article
  • Open Access
22 Citations
5,594 Views
12 Pages

Sequential and Combined Efficacious Management of Auricular Keloid: A Novel Treatment Protocol Employing Ablative CO2 and Dye Laser Therapy—An Advanced Single-Center Clinical Investigation

  • Simone Amato,
  • Steven Paul Nisticò,
  • Giovanni Pellacani,
  • Stefania Guida,
  • Anthony Rossi,
  • Caterina Longo,
  • Enzo Berardesca and
  • Giovanni Cannarozzo

8 September 2023

Auricular keloids pose significant aesthetic and functional challenges, and traditional treatments often fall short in addressing these issues. Our study presents an innovative combined approach of ablative CO2 and dye laser therapy for improved kelo...

  • Article
  • Open Access
1 Citations
7 Pages
Craniomaxillofac. Trauma Reconstr.2023, 16(4), 268-274;https://doi.org/10.1177/19433875221124406 
(registering DOI)

30 August 2022

Study Design: A prospective randomized comparative study was conducted to evaluate the postsurgical scar with Supraorbital Eyebrow (SE) Approach and Upper Blepharoplasty (UB) Approach used for open reduction and internal fixation (ORIF) of zygomatico...

  • Case Report
  • Open Access
9 Citations
8,123 Views
11 Pages

Minimally Invasive Harvesting Technique for Costal Cartilage Graft: Donor Site, Morbidity and Aesthetic Outcomes

  • Umberto Committeri,
  • Antonio Arena,
  • Emanuele Carraturo,
  • Simona Barone,
  • Giovanni Salzano,
  • Domenico Mariniello,
  • Giacomo De Riu,
  • Luigi Angelo Vaira,
  • Francesco Giovacchini and
  • Pasquale Piombino
  • + 1 author

12 May 2023

Cartilage grafts are well-known as being reliable in reconstructive surgery for craniofacial pathologies. The aim of this study is to describe a new technique which requires an incision smaller than 1.5 cm but is still effective for harvesting cartil...

  • Article
  • Open Access
30 Citations
6,278 Views
13 Pages

Correlation between Collagen Type I/III Ratio and Scar Formation in Patients Undergoing Immediate Reconstruction with the Round Block Technique after Breast-Conserving Surgery

  • Hyo-young Kim,
  • Ho-young Im,
  • Hee-kyung Chang,
  • Hwan-do Jeong,
  • Jin-hyung Park,
  • Hong-il Kim,
  • Hyung-suk Yi and
  • Yoon-soo Kim

The aim of this study was to investigate the relationship between the collagen type I/III ratio and scarring in patients who underwent immediate reconstruction with the round block technique (RBT) after breast conservation surgery. Seventy-eight pati...

  • Article
  • Open Access
57 Views
12 Pages

Association Between Rehabilitation Frequency and Functional Outcomes After Burn Injury: A Single-Center Retrospective Analysis of Confounding by Indication

  • Yazeed Temraz,
  • Theeb Al Salem,
  • Shaimaa Khan,
  • Raghad Alshehri,
  • Lina Alosaimi,
  • Mariam Hantoul,
  • Rahaf Alrajhi,
  • Rayya Alabdali,
  • Amal Bahumayim and
  • Abdulmajeed Al Ehaideb
  • + 2 authors

19 January 2026

Objective: To identify key predictors of clinical outcomes in burn survivors and clarify the role of mixed-depth burns and confounding by indication in observational rehabilitation research. Design: Retrospective cohort study using data from a burn r...

  • Article
  • Open Access
2,784 Views
11 Pages

Assessment of the Effect of Kinesiology Taping on Scar Treatment in Children

  • Justyna Pogorzelska,
  • Agata Michalska and
  • Anna Zmyślna

Background: The consequences of injuries resulting from accidents are among the most common health disorders in children. A scar forms at the site of the injury. In the treatment of scars, not all methods used in adults can be used in children. The a...

  • Article
  • Open Access
733 Views
13 Pages

15 November 2025

Background: Cesarean section (CS) frequently results in abdominal scarring, affecting recovery, aesthetics, and quality of life. Platelet-rich plasma (PRP), an autologous concentrate rich in growth factors, may enhance wound healing. This pilot trial...

  • Case Report
  • Open Access
3 Citations
3,598 Views
12 Pages

Meek Micro-Skin Grafting and Acellular Dermal Matrix in Pediatric Patients: A Novel Approach to Massive Extravasation Injury

  • Michele Maruccia,
  • Pasquale Tedeschi,
  • Claudia Corrao,
  • Rossella Elia,
  • Simone La Padula,
  • Pietro G. Di Summa,
  • Giulio M. M. Maggio and
  • Giuseppe Giudice

10 July 2023

(1) Background: Extravasation injuries in pediatric patients can lead to significant harm if they are not promptly diagnosed and treated. However, evidence-based standardization on extravasation management remains limited, particularly for extensive...

  • Article
  • Open Access
8 Citations
5,859 Views
14 Pages

Efficacy of Botulinum Toxin Type A for Prevention of Post-Mastectomy Scar in Transmen: A Prospective, Randomized Study

  • Waranaree Winayanuwattikun,
  • Vasanop Vachiramon,
  • Teerapong Rattananukrom,
  • Pasita Palakornkitti and
  • Ngamcherd Sitpahul

31 October 2023

Background: Subcutaneous mastectomies in transmen have been gaining popularity. However, post-operative scars are an inevitable consequence. Recently, Botulinum neurotoxin A (BoNT-A) has shown positive effects in scar prevention. The objective of thi...

  • Article
  • Open Access
3 Citations
7,982 Views
38 Pages

Therapeutic Efficacy of Plant-Derived Exosomes for Advanced Scar Treatment: Quantitative Analysis Using Standardized Assessment Scales

  • Lidia Majewska,
  • Agnieszka Kondraciuk,
  • Iwona Paciepnik,
  • Agnieszka Budzyńska and
  • Karolina Dorosz

25 July 2025

Background: Wound healing and scar management remain significant challenges in dermatology and aesthetic medicine. Recent advances in regenerative medicine have introduced plant-derived exosome-like nanoparticles (PDENs) as potential therapeutic agen...

  • Article
  • Open Access
1,039 Views
14 Pages

28 October 2025

Background/Objectives: Hysterectomy is the most common gynecologic surgical procedure. While extensive research has been conducted on the advantages of laparoscopy, the gynecology literature lacks sufficient studies on scar-related outcomes, patient...

  • Article
  • Open Access
19 Citations
6,153 Views
11 Pages

Postburn hypertrophic scarring is a common complication in burn injuries to the hands, often associated with impaired hand function. We evaluated the effects of extracorporeal shock wave therapy (ESWT), compared to a sham stimulation therapy, on hype...

  • Article
  • Open Access
6 Citations
5,113 Views
9 Pages

15 November 2022

Compression therapy for burn scars can accelerate scar maturation and improve clinical symptoms (pruritus and pain). This study objectively verified the effect of pressure garment therapy in maintaining a therapeutic pressure range for hypertrophic s...

  • Article
  • Open Access
24 Citations
8,651 Views
12 Pages

Novel Application of Cultured Epithelial Autografts (CEA) with Expanded Mesh Skin Grafting Over an Artificial Dermis or Dermal Wound Bed Preparation

  • Sadanori Akita,
  • Kenji Hayashida,
  • Hiroshi Yoshimoto,
  • Masaki Fujioka,
  • Chikako Senju,
  • Shin Morooka,
  • Gozo Nishimura,
  • Nobuhiko Mukae,
  • Kazuo Kobayashi and
  • Nagasaki University plastic surgeons group
  • + 7 authors

Cultured epithelial autografts (CEA) with highly expanded mesh skin grafts were used for extensive adult burns covering more than 30% of the total body surface area. A prospective study on eight patients assessed subjective and objective findings up...

  • Article
  • Open Access
940 Views
15 Pages

Hybrid Fractional Laser and Autologous Lipofilling: A Synergistic Strategy for Functional and Aesthetic Scar Remodeling

  • Gabriele Delia,
  • Lucia Quattrocchi,
  • Pietro Micieli,
  • Damiano Tambasco,
  • Roberta Albanese and
  • Fabiana Battaglia

23 September 2025

Background: Scar management remains a significant challenge in plastic and reconstructive surgery, particularly when addressing atrophic, retractile, or fibrotic scars. Autologous fat grafting and hybrid fractional laser therapy have independently sh...

  • Article
  • Open Access
5 Citations
3,576 Views
10 Pages

The Jaws Brachioplasty: An Original Technique: Improving Aesthetic Outcomes in Arm Lift Procedures

  • Giuseppe Nisi,
  • Francesco Ruben Giardino,
  • Martino Giudice,
  • Giorgio Fasano,
  • Roberto Cuomo and
  • Luca Grimaldi

27 August 2022

(1) Background: The increase in the number of bariatric surgery procedures has led plastic surgeons to look for new approaches to improve outcomes of body-contouring surgeries. A major concern in brachioplasty is the scarring process. Here, we propos...

  • Article
  • Open Access
16 Citations
3,635 Views
16 Pages

The Role of Local Inflammation and Hypoxia in the Formation of Hypertrophic Scars—A New Model in the Duroc Pig

  • Sebastian P. Nischwitz,
  • Julia Fink,
  • Marlies Schellnegger,
  • Hanna Luze,
  • Vladimir Bubalo,
  • Carolin Tetyczka,
  • Eva Roblegg,
  • Christian Holecek,
  • Martin Zacharias and
  • Petra Kotzbeck
  • + 1 author

24 December 2022

Hypertrophic scars continue to be a major burden, especially after burns. Persistent inflammation during wound healing appears to be the precipitating aspect in pathologic scarring. The lack of a standardized model hinders research from fully elucida...

  • Article
  • Open Access
2 Citations
3,027 Views
10 Pages

18 December 2024

Background/Objectives: We treated deep partial-thickness burns of the hands and feet in four cases using a combination of NexoBrid and ReCell autologous cell regeneration techniques, without conventional split-thickness skin graft, with good results...

  • Systematic Review
  • Open Access
1,430 Views
20 Pages

30 November 2025

Background/Objectives: Scarring frequently lowers quality of life and can have both functional and aesthetic impacts. Recently it has been debated whether platelet-rich plasma (PRP) can be used as a therapy modality for improving scar outcomes, given...

  • Article
  • Open Access
4 Citations
3,362 Views
16 Pages

From In Silico Simulation between TGF-β Receptors and Quercetin to Clinical Insight of a Medical Device Containing Allium cepa: Its Efficacy and Tolerability on Post-Surgical Scars

  • Terenzio Cosio,
  • Gaetana Costanza,
  • Filadelfo Coniglione,
  • Alice Romeo,
  • Federico Iacovelli,
  • Laura Diluvio,
  • Emi Dika,
  • Ruslana Gaeta Shumak,
  • Piero Rossi and
  • Elena Campione
  • + 2 authors

21 August 2023

(1) Objective: Keloid and hypertrophic scars are a challenge in clinical management, causing functional and psychological discomfort. These pathological scars are caused by a proliferation of dermal tissue following skin injury. The TGF-β/Smad s...

  • Article
  • Open Access
716 Views
13 Pages

14 November 2025

Background: Cesarean delivery is a frequent surgical procedure associated with postoperative scarring, which may impact both the aesthetic and functional recovery of patients. Platelet-rich plasma (PRP), a concentration of autologous platelets contai...

  • Article
  • Open Access
8 Citations
5,753 Views
11 Pages

A Randomized Controlled Trial of Three Advanced Wound Dressings in Split-Thickness Skin Grafting Donor Sites—A Personalized Approach?

  • Andrzej Hecker,
  • David Benjamin Lumenta,
  • Petra Brinskelle,
  • Isabelle Sawetz,
  • Andreas Steiner,
  • Birgit Michelitsch,
  • Herwig Friedl,
  • Daniel Gmainer,
  • Lars-Peter Kamolz and
  • Raimund Winter

27 August 2022

Background: Split-thickness skin grafting (STSG) is a frequently used reconstructive technique, and its donor site represents a standardized clinical model to evaluate wound dressings. We compared hydroactive nanocellulose-based, silver-impregnated a...

  • Systematic Review
  • Open Access
2 Citations
1,768 Views
14 Pages

18 March 2025

Background and Objectives: Burn injuries, particularly partial-thickness burns, often require advanced therapies to improve re-epithelialization and scar quality. This study aims to evaluate the efficacy of autologous skin cell suspensions, such as R...

  • Article
  • Open Access
8 Citations
3,668 Views
13 Pages

Evaluation of Scar Quality after Treatment of Superficial Burns with Dressilk® and Suprathel®—In an Intraindividual Clinical Setting

  • Jennifer Lynn Schiefer,
  • Janine Andreae,
  • Paul Christian Fuchs,
  • Rolf Lefering,
  • Paul Immanuel Heidekrueger,
  • Alexandra Schulz and
  • Mahsa Bagheri

18 May 2022

Background: Various synthetic and biological wound dressings are available for the treatment of superficial burns, and standard care differs among hospitals. Nevertheless, the search for an ideal wound dressing offering a safe healing environment as...

  • Article
  • Open Access
1 Citations
5,315 Views
14 Pages

10 July 2024

Background: Pediatric forearm fractures represent a substantial proportion of childhood injuries, requiring effective and minimally invasive treatments. Our study investigated the mid-term outcomes of biodegradable poly-L-lactide-co-glycolide (PLGA)...

  • Case Report
  • Open Access
1,052 Views
9 Pages

Cultured epidermal autografts (CEAs) serve as an alternative permanent skin replacement, though high costs often limit their use in resource-constrained settings and to life-saving cases. This case report presents the first documented cosmetic applic...

  • Article
  • Open Access
10 Citations
1,422 Views
9 Pages

The comparison of two methods of treatment evaluating complications and deficiency of functions of hands after deep partial skin thickness hand burns

  • Kęstutis Maslauskas,
  • Rytis Rimdeika,
  • Jolita Rapolienė,
  • Žilvinas Saladžinskas,
  • Donatas Samsanavičius and
  • Vygintas Kaikaris

28 September 2008

Hands actively participate in daily activities of a human; therefore, hands are the most vulnerable parts of the human body. People injure hands so often because namely hands are in the closest position to the dangerous equipment. According to the da...

  • Article
  • Open Access
5 Citations
4,161 Views
18 Pages

14 March 2024

Background and Objectives: Burn surgery on the hands is a difficult procedure due to the complex anatomy and fragility of the area. Enzymatic debridement has been shown to effectively remove burn eschar while minimizing damage to the surrounding tiss...

  • Article
  • Open Access
2,678 Views
11 Pages

Evaluation of Esthetic Results after Mass Removal with Elliptical Skin Excision Using Ultrasonography to Measure Skin Thickness

  • Sang Seok Woo,
  • Hongki Gwak,
  • Ki Hyun Kim,
  • Jun Won Lee,
  • Jai Koo Choi,
  • Insuck Suh and
  • Seong Hwan Kim

3 March 2024

Background: The growth of benign cutaneous masses causes the overlaying skin to expand and become thinner, especially at the central, most projected point. In this retrospective study, a surgical technique comprising an elliptical skin excision was e...

  • Article
  • Open Access
405 Views
17 Pages

17 December 2025

Background/Objectives: Non-ablative fractional lasers are widely used for scar remodeling, yet treatment parameters are often selected empirically, and thermal thresholds for consistent outcomes remain undefined. This study explored whether forward-l...

  • Article
  • Open Access
9 Citations
2,902 Views
10 Pages

The Free Myocutaneous Tensor Fasciae Latae Flap—A Workhorse Flap for Sternal Defect Reconstruction: A Single-Center Experience

  • Amir Khosrow Bigdeli,
  • Florian Falkner,
  • Benjamin Thomas,
  • Gabriel Hundeshagen,
  • Simon Andreas Mayer,
  • Eva-Maria Risse,
  • Leila Harhaus,
  • Emre Gazyakan,
  • Ulrich Kneser and
  • Christian Andreas Radu

9 March 2022

Introduction: Deep sternal wound infections (DSWI) after cardiac surgery pose a significant challenge in reconstructive surgery. In this context, free flaps represent well-established options. The objective of this study was to investigate the clinic...

  • Article
  • Open Access
4 Citations
2,515 Views
11 Pages

Long-Term Functional Outcomes Following Enzymatic Debridement of Deep Hand Burns Using Nexobrid®: A Retrospective Analysis

  • Asja T. Malsagova,
  • Amin El-Habbassi,
  • Moritz Billner,
  • Maresa Berns,
  • Tamas Pueski,
  • Karl J. Bodenschatz,
  • Paul I. Heidekrueger and
  • Denis Ehrl

12 August 2024

Background: For years, surgical debridement with autografting has been considered the standard of care in the treatment of severe burns of the hand. However, in recent years, enzymatic debridement has increasingly been reported as a good alternative,...

  • Article
  • Open Access
13 Citations
4,248 Views
6 Pages

The Use of Matriderm® for Scalp Full-Thickness Defects Reconstruction: A Case Series

  • Giovanni Dell’Aversana Orabona,
  • Francesco Maffia,
  • Giovanni Audino,
  • Vincenzo Abbate,
  • Cristiana Germano,
  • Paola Bonavolontà,
  • Antonio Romano,
  • Riccardo Villari,
  • Mauro Mormile and
  • Luigi Califano

13 October 2022

Background: The scalp region represent a common area affected by benignant and malignant skin tumor, and it represents a surgical challenge when it is needed to be reconstructed. The aim of this study is to present our experience with full-thickness...

  • Article
  • Open Access
16 Citations
6,988 Views
9 Pages

Efficiency of Bromelain-Enriched Enzyme Mixture (NexoBrid™) in the Treatment of Burn Wounds

  • Mihaela Pertea,
  • Vladimir Poroch,
  • Petru Ciobanu,
  • Alexandru Filip,
  • Natalia Velenciuc,
  • Sorinel Lunca,
  • Andrian Panuta,
  • Mihaela Buna-Arvinte,
  • Stefana Luca and
  • Bogdan Veliceasa

2 September 2021

Background: The use of bromelain for the removal of eschar in deep burns is considered to be effective because it does not affect the unaffected skin and leaves a clean dermis after use. The main objective of this study is to find out whether bromela...

  • Article
  • Open Access
1 Citations
1,016 Views
14 Pages

Outcome of Matrix Rotation Versus Single Incision Lateral Sulcus Mammoplasty in Upper Quadrant Breast Carcinomas

  • Emad M. Abdelrahman,
  • Sherif M. Mohsen,
  • Amr G. Mohamed,
  • Mostafa S. Abdeen,
  • Mohamed A. Elsayed,
  • Zizi M. Ibrahim,
  • Osama R. Abdelraouf,
  • Hassan Hegazy and
  • Mahmoud G. Abdelhalim

5 September 2025

Background and Objectives: The term “oncoplastic breast surgery” (OBS) incorporates plastic and oncologic concepts. Through the application of diverse mammoplasty approaches, the remaining breast tissue can be reconstructed, thereby enabl...

  • Article
  • Open Access
1,110 Views
10 Pages

Aesthetic Reconstruction of Fingertip Defect Using Second Toe Pulp Free Flap

  • Soyeon Jung,
  • Sodam Yi,
  • Seungjun Lee and
  • Seokchan Eun

19 August 2025

Background: Varioaus methods are available to address fingertip injuries, which are becoming increasingly common. Coverage should ideally involve both functional and aesthetic improvements. The second toe pulp-free flap is useful because of its simil...

  • Article
  • Open Access
7 Citations
2,716 Views
18 Pages

Fragmented Dermo-Epidermal Units (FdeU) as an Emerging Strategy to Improve Wound Healing Process: An In Vitro Evaluation and a Pilot Clinical Study

  • Michele Riccio,
  • Elena Bondioli,
  • Letizia Senesi,
  • Nicola Zingaretti,
  • Paolo Gargiulo,
  • Francesco De Francesco,
  • Pier Camillo Parodi and
  • Barbara Zavan

24 September 2023

Innovative strategies have shown beneficial effects in healing wound management involving, however, a time-consuming and arduous process in clinical contexts. Micro-fragmented skin tissue acts as a slow-released natural scaffold and continuously deli...

  • Article
  • Open Access
1,147 Views
10 Pages

Objective: This study aims to evaluate the application effect of endoscopic thyroidectomy via the gasless unilateral axillary (GUA) approach in thyroid cancer and its impact on the postoperative stress response. Methods: Ninety-four thyroid cancer pa...