29 Results Found

Resistance to tyrosine kinase inhibitors (TKIs, e.g., sorafenib and lenvatinib) presents a significant hurdle for hepatocellular carcinoma (HCC) treatment, underscoring the need to decipher the underlying mechanisms for improved therapeutic strategie...

Actin dynamics are known to orchestrate various myogenic processes in progenitor cells. Twinfilin-1 (TWF1) is an actin-depolymerizing factor that plays a crucial role in the differentiation of myogenic progenitor cells. However, little is known about...

Actin cytoskeleton dynamics have been found to regulate myogenesis in various progenitor cells, and twinfilin-1 (TWF1), an actin-depolymerizing factor, plays a vital role in actin dynamics and myoblast differentiation. Nevertheless, the molecular mec...

Transformer winding faults (TWFs) can lead to insulation breakdown, internal short circuits, and catastrophic transformer failure. Due to their low current magnitude—particularly at early stages such as inter-turn short circuits, axial or radia...

A novel deployable reflector antenna for small satellites has been designed, fabricated, and experimentally validated. The reflector utilizes a doubly curved flexible surface manufactured from a triaxially woven fabric-reinforced silicone (TWFS) comp...

Under the infrastructure of three gradually deepening layers consisting of System, Service and Software, the information entropy of the Trustworthy Workflow Management System (TWfMS) will evolve from being more precise to more undetermined, due to a...

MicroRNAs play a pivotal role in the regulation of adipose tissue function and have emerged as promising therapeutic candidates for the management of obesity and associated comorbidities. Among them, miR-1 could be a potential biomarker for metabolic...

As the virtual mirror of complex real-time business processes of organisations’ underlying information systems, the workflow management system (WfMS) has emerged in recent decades as a new self-autonomous paradigm in the open, dynamic, distributed co...

While tourism generates economic benefits at destinations, it also creates certain environmental pressures. In the global context of water scarcity, the spatial and temporal differentiation characteristics of water consumption at tourism destinations...

This paper investigates the twisted wind effect on a typical super-tall building (500-m-tall square prism) by conducting pressure model wind tunnel tests. Two twisted wind fields (TWFs) with maximum yaw angles of approximately 30° and 20°, re...

The twisted wind flow (TWF), referring to the phenomenon of wind direction varying with height, is a common feature of atmospheric boundary layer (ABL) winds, noticeably affecting the wind-resistant structural design and the wind environment assessme...

Continuous efforts are being made to improve plain concrete compressive strength and ductility by applying carbon, glass fiber, or hybrid-reinforced epoxy resin composites. The investigation centers on analyzing the axial compressive strength and str...

Gingivitis is a widespread disease commonly associated with dentin hypersensitivity, that, in turn, may complicate routine dental care, leading to plaque accumulation. We aimed to assess the antigingivitis, desensitizing, and antiplaque effects of a...

To enrich the understanding of the dynamic evolution of the water resources in North China, terrestrial water storage anomalies (TWSA) from January 2003 to June 2017 are derived using the new GRACE time-variable gravity field model Tongji-GraceCom. A...

Many countries have established grassroots forestry institutions to manage and protect small-scale forestry resources and provide technology and services to private foresters. Since the inception of township forestry workstations (TFWs) in China almo...

Breeding programs for improvement of sacha-inchi, Plukenetia volubilis L., generally aim to select individuals with greater seed yield since there is a strong correlation between seed yield and oil production. However, the manual removal of seed husk...

Water is an important resource for crop production; identifying the spatial pattern of the crop water footprint (WF) is of great significance for the optimization of water resource consumption and management in agricultural production. This study qua...

The tourism footprint family comprises the tourism ecological footprint (TEF), the tourism carbon footprint (TCF) and the tourism water footprint (TWF). The tourism footprint represents an important tool for quantitatively assessing the impact of tou...

Thresholds are an emergent property of complex systems and Coupled Natural Human Systems (CNH) because they indicate “tipping points” where a complicated array of social, environmental, and/or economic processes combine to substantially c...

The concept of green development requires that tourism development should be constrained by water and energy. This paper first constructed the calculation model of tourism water supply (TWS) based on water resources, economy, population, and employme...

The objective of the present study was to investigate the dynamic change of serum parameters and milk composition by dietary FA supplementation with ewes with different litter size from mating to lambing. The ewes were divided into six treatments (TW...

In recent years, the rapid development of tourism in China’s arid areas has led to a continuous increase in water consumption, heightening the tension between water supply and demand in the region. For this reason, drought-type tourist destinat...

The purpose of this study was to investigate the effect of maternal dietary folic acid (FA) supplementation during gestation on small intestinal development of newborn lambs of different litter sizes, focusing on the intestinal morphology and develop...

The practice of fasting recently has been purported to have clinical benefits, particularly as an intervention against obesity and its related pathologies. Although a number of different temporal dietary restriction strategies have been employed in p...

The concept of the water footprint (WF) has not adequately explored the combined effects of climate change and salinity. For this aim, the effects of future climate conditions on tomato WF irrigated with moderately saline water (EC = 2.9 dS m−1...

Background: As microRNA-142 (miR-142) is the only human microRNA gene where mutations have consistently been found in about 20% of all cases of diffuse large B-cell lymphoma (DLBCL), we wanted to determine the impact of miR-142 inactivation on protei...

Energy harvesting, which offers a never-ending energy supply, has emerged as a prominent technology to prolong the lifetime and reduce costs for the battery-powered wireless sensor networks. However, how to improve the energy efficiency while guarant...

A robust assessment of water used in agriculture, including livestock production systems and supply chains, is critical to inform diversification and the development of productivity and sustainable food production systems. This paper presents a detai...

The Pearl River Basin (PRB) is a humid subtropical system where frequent floods and recurrent droughts challenge water management. GRACE and GRACE Follow-On provide basin-scale constraints on terrestrial water storage anomalies (TWSA), yet their coar...