In crude oil production, large volumes of produced water are generated as a highly polluting waste byproduct. On average, at least two barrels of produced water are generated for every barrel of oil. This water contains oil traces in stable and compl...
Bufadienolides exert broad-spectrum pharmacological activities relevant to cardiology and novel cancer treatments. Their efficacy, toxicity, and pharmacokinetic profiles are significantly affected by modifications at carbon-3 (C3) of the steroid core...
This study explores the adsorption and catalytic degradation of 2,4,6-trinitrotoluene (TNT) from aqueous solutions, using montmorillonite-based catalysts. Commercially, montmorillonite K10 was modified through aluminum pillaring (K10-Al-PILC), follow...
Botanical insecticides and soaps are frequently proposed as environmentally safer alternatives to synthetic insecticides. However, the efficacy and selectivity of these products are often only partially supported by empirical evidence. Here, we teste...
The identification of protein-protein interaction disruptors (PPIDs) that disrupt the YAP/TAZ-TEAD interaction has gained considerable momentum. Several studies have shown that YAP/TAZ are no longer oncogenic when their interaction with the TEAD fami...
Concrete in construction has recently gained media coverage for its negative CO2 footprint, but this is not the only problem associated with its use. Due to its chemical composition, freshly poured concrete changes the pH of water coming in contact w...
Dermanyssus gallinae (PRM) is the most common blood-sucking ectoparasite in laying hens and is resistant against numerous acaricides. Silver nanoparticles (AgNPs) represent an innovative solution against PRM. The current study aimed to assess the in...
Cr(VI) is considered to be the most hazardous and toxic oxidation state of chromium and hence the development of effective removal technologies, able to provide water with Cr(VI) below the drinking water limits (US EPA 100 μg/L, European Commissio...
Oil-contaminated water is among the most significant environmental challenges from various industries and manufacturing processes. Oily water poses a severe environmental threat and is toxic to many forms of life. This study aims to investigate the p...
Hexavalent chromium [Cr (VI)] is a highly toxic and hazardous contaminant that poses serious health risks to both humans and the environment. Its presence in water sources can lead to severe health issues, including various types of cancer and respir...
Compounds derived from plants have several anticancer properties. In the current study, one guaiane-type sesquiterpene dimer, vieloplain F, isolated from Xylopia vielana species, was tested against B-Raf kinase protein (PDB: 3OG7), a potent target fo...
Broadly effective and safe anti-coronavirus agent is existentially needed. Major protease (3CLpro) is a highly conserved enzyme of betacoronaviruses. The enzyme plays pivotal role in the virus replication cycle. Thus, it is a good target of a broadly...
The search for possible alternatives to traditional flame retardants (FRs) is pushing the academic and industrial communities towards the design of new products that exhibit low environmental impact and toxicity, notwithstanding high performances, wh...
Varroa destructor is currently considered the parasite that causes the greatest damage and economic losses to honeybee farms. Its presence is often associated with that of viral and bacterial pathogens, which ultimately leads to colony collapse. Care...
Wee1-like protein kinase 2 (WEE2) is an oocyte-specific kinase that regulates meiotic arrest and fertilization. Its largely restricted expression in female germ cells and absence in somatic tissues make it a highly selective target for reproductive h...
Background: Melanin protects skin and hair from the effects of ultraviolet (UV) radiation damage, which contributes to all forms of skin cancer, including melanoma. Human melanocytes produce two main types of melanin: eumelanin provides effective pho...
16 April 2025
Introduction: Thirdhand smoke (THS) was first identified by Graham and colleagues in 1953, and nicotine was detected in household dust from smokers in 1991. Thirdhand smoke (THS) consists of toxic nicotine residues that persist on surfaces long after...
Freshwater bodies and, consequently, drinking water treatment plants (DWTPs) sources are increasingly facing toxic cyanobacterial blooms. Even though conventional treatment processes including coagulation, flocculation, sedimentation, and filtration...
Varroa destructor is an ectoparasitic mite that causes a true syndrome with complex symptoms in honeybees. For mite control, several synthetic active principles are commercially available. However, these formulations are proving less effective due to...
The ostrich oil of Struthio camelus (Ratite) found uses in folk medicine as an anti-inflammatory in eczema and contact dermatitis. The anti-inflammatory effect of a γ-lactone (5-hexyl-3H-furan-2-one) isolated from ostrich oil and its formulated nano-...
Surface chemical modification allows for the rational construction of biochar with desirable structures and functionalities for environment purification. Fruit-peel-derived adsorbing material has been well studied in the adsorption of heavy-metal rem...
Combating acquired drug resistance of EGFR tyrosine kinase (TK) is a great challenge and an urgent necessity in the management of non-small cell lung cancers. The advanced EGFR (L858R/T790M/C797S) triple mutation has been recently reported, and there...
Human development has led to increased production of oil and gas, mainly as energy sources, which, however, are responsible for contamination and metal corrosion in industrial, marine, and terrestrial environments. Lubricating oil, in particular, is...
Mediterranean countries experience a large production of olive oil, thus generating huge quantities of non-biodegradable vegetation waters. The discharge of these effluents into aquatic environments seriously affects the quality of surface waters. Th...
Background: Disinfection by-products used to obtain drinking water, including halomethanes (HMs) such as CH2Cl2, CHCl3, and BrCHCl2, induce cytotoxicity and hyperproliferation in human lung fibroblasts (MRC-5). Enzymes such as superoxide dismutase (S...
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