Skip to Content
You are currently on the new version of our website. Access the old version .

68 Results Found

  • Article
  • Open Access
16 Citations
1,606 Views
18 Pages

Gestational Diabetes Mellitus Alters Cytokine Profiles and Macrophage Polarization in Human Placenta

  • Martalice Ribeiro Barbosa,
  • Gabriela Feres de Marchi,
  • Kênia Maria Rezende Silva,
  • Danielle Cristina Honorio França and ,
  • Marcondes Alves Barbosa da Silva,
  • Jakeline Ribeiro Barbosa,
  • Laura Valdiane Luz Melo,
  • Eduardo Luzía França and
  • Adenilda Cristina Honorio-França
  • + 4 authors+ 0 author

9 November 2025

Gestational Diabetes Mellitus (GDM) is a metabolic condition characterized by glucose intolerance, which manifests or is diagnosed for the first time during pregnancy. Hyperglycemia associated with GDM can induce a systemic and local inflammatory env...

(This article belongs to the Special Issue The Relationship, Mechanisms, and Treatment Strategies of Diabetes Mellitus and Related Diseases)
  • Review
  • Open Access
33 Citations
21,716 Views
35 Pages

The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review

  • Linda P. Guamán,
  • Saskya E. Carrera-Pacheco,
  • Johana Zúñiga-Miranda,
  • Enrique Teran and ,
  • Cesar Erazo and
  • Carlos Barba-Ostria
  • + 1 author+ 0 author

30 October 2024

Background: This review investigates the impact of bioactive molecules produced by probiotics on child health, focusing on their roles in modulating gut microbiota, enhancing immune function, and supporting overall development. Key metabolites, inclu...

(This article belongs to the Special Issue The Impact of Probiotics/Prebiotics and Functional Foods in Human Health)
  • Article
  • Open Access
8 Citations
2,449 Views
20 Pages

Obesity Correlates with Chronic Inflammation of the Innate Immune System in Preeclampsia and HELLP Syndrome during Pregnancy

  • Julia Rimboeck,
  • Michael Gruber,
  • Marco Weigl,
  • Pia Huber and ,
  • Dirk Lunz and
  • Walter Petermichl
  • + 1 author+ 0 author

HELLP syndrome is characterized by hemolysis, elevated liver enzymes, and a low platelet count and poses an increased risk to the pregnant woman and the unborn child. Individual risk factors such as obesity may alter immunocompetence and influence th...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
4 Citations
3,139 Views
15 Pages

Carbohydrate-Mediated Pregnancy Gut Microbiota and Neonatal Low Birth Weight

  • Hong-Ren Yu,
  • Yao-Tsung Yeh,
  • Hong-Tai Tzeng,
  • Hong-Ying Dai and ,
  • Wei-Chia Lee,
  • Kay L. H. Wu,
  • Julie Y. H. Chan,
  • You-Lin Tain and
  • Chien-Ning Hsu
  • + 4 authors+ 0 author

28 April 2024

The effects of gut microbiota on the association between carbohydrate intake during pregnancy and neonatal low birth weight (LBW) were investigated. A prospective cohort study was conducted with 257 singleton-born mother–child pairs in Taiwan,...

(This article belongs to the Section Nutrition in Women)
  • Article
  • Open Access
7 Citations
4,730 Views
17 Pages

23 August 2024

During the COVID-19 pandemic, many DeafBlind children were left without access to educational services when schools went remote. This article presents findings from a project that brought DeafBlind adults into the homes of DeafBlind children during a...

(This article belongs to the Special Issue Coexpressivity, Gesture, and Language Emergence: Modality, Composition, and Creation)
  • Review
  • Open Access
14 Citations
7,138 Views
22 Pages

3 February 2022

In this review, we discuss the functions and main effects on pregnancy outcomes of three agents that have the ability to induce epigenetic modifications: valproic acid (VPA), a well-known teratogen that is a histone deacetylase inhibitor; S-adenosylm...

(This article belongs to the Special Issue Epigenetic Drugs)
  • Case Report
  • Open Access
4 Citations
2,917 Views
13 Pages

Transcutaneous Spinal Stimulation Combined with Locomotor Training Improves Functional Outcomes in a Child with Cerebral Palsy: A Case Study

  • Darryn Atkinson,
  • Kristen Barta,
  • Fabian Bizama,
  • Hazel Anderson and ,
  • Sheila Brose and
  • Dimitry G Sayenko
  • + 1 author+ 0 author

26 November 2024

Background and Purpose: activities-based locomotor training (AB-LT) is a restorative therapeutic approach to the treatment of movement deficits in people with non-progressive neurological conditions, including cerebral palsy (CP). Transcutaneous spin...

(This article belongs to the Section Pediatric Neurology & Neurodevelopmental Disorders)
  • Article
  • Open Access
2 Citations
4,711 Views
13 Pages

Single-Cell RNA Sequencing Reveals Distinct Cardiac-Derived Stromal Cell Subpopulations

  • Jessica R. Hoffman,
  • Arun R. Jayaraman,
  • Sruti Bheri and
  • Michael E. Davis

Human cardiac-derived c-kit+ stromal cells (CSCs) have demonstrated efficacy in preclinical trials for the treatment of heart failure and myocardial dysfunction. Unfortunately, large variability in patient outcomes and cell populations remains a prob...

(This article belongs to the Special Issue Models and Methods for Computational Cardiology)
  • Article
  • Open Access
3 Citations
1,055 Views
14 Pages

Integrating CTLA-4 Genetics and Soluble Isoforms for the Stratification of HCV-Related Hepatocellular Carcinoma Risk and Aggressiveness

  • Marwa Hassan,
  • Walaa H. El-Maadawy,
  • Sally A. Fahim,
  • Sherihan M. Youssef and ,
  • Omaima Mostafa Badran and
  • Mahmoud Balata
  • + 1 author+ 0 author

15 November 2025

Host genetic factors influencing immune regulation are believed to modulate susceptibility to hepatitis C virus (HCV) and related hepatocellular carcinoma (HCC). This study aimed to investigate the association of Cytotoxic T-lymphocyte-associated ant...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
880 Views
12 Pages

Effects of Maternal Heartbeat Exposure on Neonatal Autonomic Regulation

  • Sara Puddu,
  • Stefano Vicentin,
  • Filippo Zemin,
  • Paola Veronese and
  • Elisa Cainelli

Background: During intrauterine life, the fetus is continuously exposed to rhythmic sensory stimuli; among these, the maternal heartbeat is one of the earliest and most biologically salient, contributing to the early organization of physiological reg...

  • Review
  • Open Access
91 Citations
14,160 Views
22 Pages

Nurturing the Early Life Gut Microbiome and Immune Maturation for Long Term Health

  • Shaillay Kumar Dogra,
  • Cheong Kwong Chung,
  • Dantong Wang,
  • Olga Sakwinska and ,
  • Sara Colombo Mottaz and
  • Norbert Sprenger
  • + 1 author+ 0 author

Early life is characterized by developmental milestones such as holding up the head, turning over, sitting up and walking that are typically achieved sequentially in specific time windows. Similarly, the early gut microbiome maturation can be charact...

(This article belongs to the Special Issue Novel Insights into the Infant Gut Microbiome and Host–Microbe Interactions)
  • Review
  • Open Access
952 Views
24 Pages

Hepatitis B Virus: Epidemiology, Prophylaxis, Therapy, Clinical Outcomes, and Novel Therapeutic Directions

  • Uzair Iqbal,
  • Khadija Khalid,
  • Yunus Yukselten,
  • Farooq Ahmad and ,
  • Haseeb Ahmad,
  • Abdur Rehman Khalid,
  • Mohamed Shaltout and
  • Richard E. Sutton
  • + 3 authors+ 0 author

7 September 2026

Hepatitis B virus (HBV) infection is a worldwide health concern that infects nearly 254 million people globally and causes more than 1 million deaths annually. The highest prevalence is seen in sub-Saharan Africa and the Western Pacific region. Cirrh...

(This article belongs to the Section Molecular Medicine)
  • Article
  • Open Access
1,101 Views
19 Pages

Neurocognitive Correlates of Diagnostic Heterogeneity in Children with ADHD: The Differential Contributions of Cognitive Disengagement Syndrome, Symptom Severity, and Anxiety

  • İbrahim Adak,
  • Esin Özdeniz Varan,
  • Nergis Eyüpoğlu,
  • Ayşim Alpman and ,
  • Zeynep Durmuş,
  • Oğuz Bilal Karakuş,
  • İpek Süzer Gamlı and
  • Özalp Ekinci
  • + 3 authors+ 0 author

Background/Objectives: Attention-Deficit/Hyperactivity Disorder (ADHD) shows substantial cognitive heterogeneity, complicating individualized clinical formulation. This study examined whether Cognitive Disengagement Syndrome (CDS), anxiety, and ADHD...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition)
  • Article
  • Open Access
12 Citations
5,338 Views
23 Pages

Mindful Coping Power Effects on Children’s Autonomic Nervous System Functioning and Long-Term Behavioral Outcomes

  • Caroline L. Boxmeyer,
  • Catanya G. Stager,
  • Shari Miller,
  • John E. Lochman and ,
  • Devon E. Romero,
  • Nicole P. Powell,
  • Chuong Bui and
  • Lixin Qu
  • + 3 authors+ 0 author

23 May 2023

Mindful Coping Power (MCP) was developed to enhance the effects of the Coping Power (CP) preventive intervention on children’s reactive aggression by integrating mindfulness training into CP. In prior pre–post analyses in a randomized tri...

(This article belongs to the Special Issue (Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice)
  • Article
  • Open Access
2 Citations
12,675 Views
14 Pages

The Flip Side of the Coin: Giftedness in Pediatric Acute-Onset Neuropsychiatric Syndrome

  • Denise Calaprice,
  • Ryan Terreri,
  • Christopher Whitty,
  • Ryan Whitty and
  • Janice Tona

16 December 2024

Background/Objectives: Individuals with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), an immune-modulated disorder, experience exacerbation-related neuropsychiatric symptoms, functional impairments, and high rates of developmental diagnosis...

(This article belongs to the Special Issue Advances in Obsessive–Compulsive Disorders in Children: Epidemiology, Diagnosis and Treatment)
  • Article
  • Open Access
1 Citations
1,090 Views
14 Pages

Radiotherapy for Liver-Confined Hepatocellular Carcinoma in Elderly Patients with Comorbidity

  • Sun Hyun Bae,
  • Young Seok Kim,
  • Sang Gyune Kim,
  • Jeong-Ju Yoo and ,
  • Jae Myeong Lee,
  • Sanghyeok Lim,
  • Jae Hong Jung and
  • Chan Kyu Kim
  • + 3 authors+ 0 author

27 December 2025

Background: Globally, the incidence rate of hepatocellular carcinoma (HCC) has increased among elderly patients. Elderly patients often present with multiple comorbidities that affect treatment tolerance and outcomes, and the optimal management strat...

(This article belongs to the Section Cancer Therapy)
  • Protocol
  • Open Access
6 Citations
5,126 Views
16 Pages

Despite the extensive evidence on the benefits of physical activity (PA) in older adults, including reduced risk of disease, mortality, falls, and cognitive and functional decline, most do not attain sufficient PA levels. Theoretical work suggests th...

(This article belongs to the Special Issue The Challenges and Opportunities for Promoting Active Healthy Ageing)
  • Systematic Review
  • Open Access
4 Citations
2,579 Views
76 Pages

6 February 2026

Introduction: Resting-state EEG (rsEEG) is a scalable window onto trait-like “executive readiness,” but findings have been fragmented by task impurity on the executive-function (EF) side and heterogeneous EEG pipelines. This review synthe...

(This article belongs to the Special Issue Innovations in Neurorehabilitation—2nd Edition)

of 2