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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Vaccine Efficacy and Safety in Transplant Recipients

edited by

Ger Rijkers

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2617 | Submission Open

Keywords: transplant recipients; vaccination; kidney; heart; lung; stem cell transplants; safety; antibody response; efficacy

(This special issue belongs to the Section Vaccine Efficacy and Safety)

New Approaches to Vaccine Development and Delivery

edited by

Antonio Carlos de Freitas

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2203 | Submission Open

Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control

(This special issue belongs to the Section Vaccination Optimization)

Advances in Allergy, Clinical Immunology, and Vaccines

edited by

Laura Franza

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1445 | Submission Open

Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution

(This special issue belongs to the Section Clinical Immunology)

Research in Vaccine Adjuvants: Innovations and Challenges

edited by Haibo Li and

Hongwu Sun

submission deadline 31 Oct 2025 | 1 articles | Viewed by 715 | Submission Open

Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges

(This special issue belongs to the Section Vaccine Adjuvants)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 31 Oct 2025 | Viewed by 497 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

The Development of Recombinant and Subunit Vaccines Against Infectious Diseases

edited by

Abu Salim Mustafa

submission deadline 31 Oct 2025 | Viewed by 468 | Submission Open

Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants

(This special issue belongs to the Section Vaccines against Infectious Diseases)

The Development of Peptide-Based Vaccines

edited by

José Manuel Pérez De La Lastra

and

José de la Fuente

submission deadline 31 Oct 2025 | Viewed by 214 | Submission Open

Keywords: peptide antigens; vaccine design; immunogenicity; epitope mapping; adjuvants; multi-epitope vaccines; personalized peptide vaccines; vaccine delivery systems; computational vaccine design; synthetic peptides

Infectious Diseases and Immunization in Animals

edited by

Fábio Abade dos Santos

, Ezgi Akdesir and

Jelena Prpić

submission deadline 31 Oct 2025 | Viewed by 173 | Submission Open

Keywords: animal vaccination; zoonotic diseases; One Health; host– pathogen interaction; veterinary immunology; emerging infectious diseases; antimicrobial resistance; vaccine development

(This special issue belongs to the Section Veterinary Vaccines)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 31 Oct 2025 | Viewed by 164 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-host Immune Interface)

Nanomaterial Application in Vaccines

edited by

Tian Xia

and

Bingbing Sun

submission deadline 31 Oct 2025 | Viewed by 38 | Submission Open

Keywords: nanomaterials; vaccine delivery; immunogenicity enhancement; tolerogenic nanovaccine; nanotechnology; vaccine stability; vaccine design; nanoparticles; immunization strategies; biotechnology in vaccines

Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy

edited by

Ruchi Roy

submission deadline 31 Oct 2025 | Viewed by 27 | Submission Open

Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Bioengineering in Vaccine Design and Delivery

edited by

Massimo Zollo

submission deadline 1 Nov 2025 | 3 articles | Viewed by 6873 | Submission Open

Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles

(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 1 Nov 2025 | 2 articles | Viewed by 2512 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition

edited by

Fabrizio Maggi

and

Licia Bordi

submission deadline 30 Nov 2025 | 13 articles | Viewed by 49247 | Submission Open

Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Feature Papers of DNA and mRNA Vaccines

edited by

Jorge H. Leitão

submission deadline 30 Nov 2025 | 9 articles | Viewed by 35548 | Submission Open

(This special issue belongs to the Section DNA and mRNA Vaccines)

Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Nov 2025 | 4 articles | Viewed by 6344 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease

(This special issue belongs to the Section Vaccine Efficacy and Safety)

Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects

edited by

Eyad Elkord

and Afsheen Raza

submission deadline 30 Nov 2025 | 4 articles | Viewed by 6244 | Submission Open

Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Advanced Concepts in Vaccines in Public Health

edited by

Lamberto Manzoli

and Maria Elena Flacco

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4882 | Submission Open

Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness

(This special issue belongs to the Section Human Vaccines and Public Health)

Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition

edited by Juan Yang and Wei Wang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1278 | Submission Open

Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

The Vaccine Development and Study of Swine Diseases

edited by

Chunhe Guo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1192 | Submission Open

Keywords: swine diseases; viruses; vaccines; protection; control

(This special issue belongs to the Section Veterinary Vaccines)

Intracellular Parasites: Immunology, Resistance, and Therapeutics

edited by

Rajesh Mani

and Nagendran Tharmalingam

submission deadline 30 Nov 2025 | Viewed by 1099 | Submission Open

Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles

(This special issue belongs to the Section Pathogens-host Immune Interface)

New Insights into Vaccination and Public Health: 2nd Edition

edited by

Paolo Castiglia

and

Antonella Arghittu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 915 | Submission Open

Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases

(This special issue belongs to the Section Human Vaccines and Public Health)

Cost-Effectiveness of Vaccines and Public Health

edited by Sachin A. Silva

submission deadline 30 Nov 2025 | Viewed by 548 | Submission Open

Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines Design Against Porcine Circovirus

edited by

Jianli Shi

Junki Maruyama

and

Takeshi Saito

submission deadline 30 Nov 2025 | Viewed by 495 | Submission Open

Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method

(This special issue belongs to the Section Veterinary Vaccines)

Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination

edited by

Paul Shing-fong Chan

submission deadline 30 Nov 2025 | Viewed by 325 | Submission Open

Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

Bacterial and Viral Infections: Current Challenges and Vaccine Innovations

edited by Dima El Safadi

submission deadline 30 Nov 2025 | Viewed by 301 | Submission Open

Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health

(This special issue belongs to the Section Pathogens-host Immune Interface)

Tuberculosis Diagnosis and Vaccines Research

edited by Shumaila Nida Javed Tunio

submission deadline 30 Nov 2025 | Viewed by 213 | Submission Open

Keywords: developing new diagnostic methods; new drugs; new vaccines for tuberculosis

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Animal Infectious Diseases and Vaccinology in One Health

edited by

Edith Rojas-Anaya

and Elizabeth Loza-Rubio

submission deadline 30 Nov 2025 | Viewed by 140 | Submission Open

Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses

(This special issue belongs to the Section Veterinary Vaccines)

Advances in HIV Vaccine Development, 2nd Edition

edited by

Xueling Wu

submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open

Keywords: HIV; envelope glycoprotein; vaccine; adjuvant; antibody; neutralization; ADCC; ADCP; complement; cellular immune response

(This special issue belongs to the Section HIV Vaccines)

Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition

edited by

Imran Saleem

submission deadline 30 Nov 2025 | Viewed by 64 | Submission Open

Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology

(This special issue belongs to the Section Vaccine Adjuvants)

Vaccines for Porcine Coronaviruses

edited by

Jung-Eun Park

submission deadline 1 Dec 2025 | Viewed by 273 | Submission Open

Keywords: porcine coronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); porcine deltacoronavirus (PDCoV); swine acute diarrhea syndrome coronavirus (SADS-CoV); porcine respiratory coronavirus (PRCV); porcine hemagglutinating encephalomyelitis virus (PHEV); vaccine; immune response; protective efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Public Health in the 21st Century

edited by

Evridiki Patelarou

Enkeleint A. Mechili

and

Athina E. Patelarou

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4921 | Submission Open

Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development

(This special issue belongs to the Section Human Vaccines and Public Health)

Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

edited by Wandi Zhu

submission deadline 20 Dec 2025 | Viewed by 22 | Submission Open

Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity

Health Technology Assessment of Vaccination: Strategies, Public Health and Values

edited by Maarten J. Postma, Jurjen Van der Schans and

Cornelis Boersma

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5534 | Submission Open

Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines Against Poultry Viruses

edited by

Xiuli Feng

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4502 | Submission Open

Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs

(This special issue belongs to the Section Veterinary Vaccines)

Cutting-Edge Cancer Vaccines Enhanced by Nanotechnology

edited by

Xiupeng Wang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2456 | Submission Open

Keywords: cancer immunotherapy; nanotechnology; cancer vaccine; adjuvant; in situ cancer vaccine; personalized cancer vaccine; combination cancer therapy; nanoparticle

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Strategies for the Monitoring, Treatment, and Prevention of Mpox and Other Poxvirus Infections

edited by Patrick Obermeier and Susanne Buder

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2142 | Submission Open

Keywords: poxvirus; mpox; emerging infection; epidemiology; surveillance; vaccine; vaccine efficacy; immunity; one health; global health

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Strategies to Enhance Vaccine Uptake and Immunization Among Underserved Populations/Vulnerable Groups

edited by

Álvaro Francisco Lopes De Sousa

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1912 | Submission Open

Keywords: vaccine uptake; vulnerable populations; health interventions; vaccine hesitancy; public health strategies; health education and equity

(This special issue belongs to the Section Human Vaccines and Public Health)

Prevention of Human Papillomavirus (HPV) and Vaccination

edited by

Sara Boccalini

Paolo Bonanni

and

Angela Bechini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1860 | Submission Open

Keywords: HPV vaccination; screening; PAP test; HPV-DNA test; HPV vaccine coverage; vaccine hesitancy; promotion

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccination and Public Health Strategy

edited by Shenglan Tang, Lance E. Rodewald and Taufique Joarder

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1693 | Submission Open

Keywords: immunization Agenda 2030; vaccine equity; new vaccines introduction; sustainable immunization and financing; sustainable vaccine supply and procurement

(This special issue belongs to the Section Human Vaccines and Public Health)

The Development of Vaccine Against Parasite Infection

edited by

Kathryn M. Jones

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1228 | Submission Open

Keywords: adaptive immune response; vaccine; adjuvant; protozoal; helminth; apicomplexan; delivery systems; epidemiology; needs assessment

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for the Vulnerable Population

edited by

My Kieu Ha

submission deadline 31 Dec 2025 | 1 articles | Viewed by 985 | Submission Open

Keywords: vaccines; vulnerable populations; infectious diseases; immunization

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines and Antibody-Based Therapeutics Against Infectious Disease

edited by Suman Kundu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 889 | Submission Open

Keywords: infectious disease; vaccine; antibody; therapy; agriculture; protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine and Vaccination in Veterinary Medicine

edited by

Diqiu Liu

and Wen Shi

submission deadline 31 Dec 2025 | 2 articles | Viewed by 802 | Submission Open

Keywords: veterinary vaccine; vaccine design; vaccine safety and efficacy; immune response; immunization

(This special issue belongs to the Section Veterinary Vaccines)

Epidemiology of Diseases Preventable by Vaccination

edited by

Caterina Elisabetta Rizzo

Cristina Genovese

and

Roberto Venuto

submission deadline 31 Dec 2025 | Viewed by 740 | Submission Open

Keywords: vaccine safety and efficacy; vaccination strategies; epidemiological surveillance; vaccine equity; disease burden and impact

(This special issue belongs to the Section Epidemiology)

SARS-CoV-2, Influenza and Other Respiratory Viruses: Preventive Measures Affecting the Determinants of Health and Disease

edited by

Marco Del Riccio

and

Saverio Caini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 677 | Submission Open

Keywords: respiratory; viruses; SARS-CoV-2; human influenza; respiratory syncytial virus; vaccines; vaccination strategies; disease burden

(This special issue belongs to the Section Epidemiology)

Innovative Technology in Vaccine Development: Advancing Immunization Strategies

edited by Aziz Chentoufi

submission deadline 31 Dec 2025 | Viewed by 340 | Submission Open

Keywords: vaccine; mRNA; viral vectors; nanoparticle; structural vaccinology; artificial intelligence; immunization

Animal Virus Infection, Immunity and Vaccines: 2nd Edition

edited by

Hani Boshra

submission deadline 31 Dec 2025 | Viewed by 303 | Submission Open

Keywords: zoonotic and veterinary diseases; viruses; vaccinology; immunology

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination Against Viral Hepatitis for Prevention and Treatment

edited by Antony Black and Monique Andersson

submission deadline 31 Dec 2025 | Viewed by 292 | Submission Open

Keywords: viral hepatitis; vaccines; coverage; epidemiology; immunology; efficacy

(This special issue belongs to the Section Hepatitis Virus Vaccines)

The Development of mRNA Vaccines

edited by Minghui Yang, Yuming Li and Bo Hu

submission deadline 31 Dec 2025 | Viewed by 277 | Submission Open

Keywords: nanoparticle delivery system; mRNA vaccines; infectious disease; tumor immunity; adjuvant

(This special issue belongs to the Section DNA and mRNA Vaccines)

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