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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1424 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Immune Response to Dengue Viral Infection

edited by

Bo Peng

and Xiaolu Shi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1375 | Submission Open

Keywords: dengue virus infection; immune response; immunity; viral infection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1297 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

BCG Vaccine and Beyond: Innovations in Tuberculosis Vaccination and Inflammation-Related Disease Prevention

edited by

Xiao-Yong Fan

and

Zhi-Dong Hu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1224 | Submission Open

Keywords: tuberculosis; vaccine; vaccination; immune response; adjuvant; T-cell; immune memory; adaptive immunity; innate immune memory; correlates of protection

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Influenza Vaccines and Influenza Vaccination in Europe

edited by George Kassianos

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1222 | Submission Open

Keywords: vaccines; vaccine design; influenza; vaccination rates; vaccine efficacy; effectiveness; vaccine safety; vaccine development; adjuvant; recombinant influenza vaccine; cell-based; egg-derived; mRNA; vaccination strategies; vaccine response; antivirals

(This special issue belongs to the Section Influenza Virus Vaccines)

New Horizons in the Fight Against Vector-Borne Diseases and Parasitic Infestations: From Basic Research to Applied Studies in Vaccines

edited by

Rodolfo Cordeiro Giunchetti

and

Maykelin Fuentes Zaldivar

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1203 | Submission Open

Keywords: vaccine; global health; neglected diseases; vectors

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for Poultry Viruses

edited by

Dingxiang Liu

and Ying Liao

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1185 | Submission Open

Keywords: poultry viruses; vaccines; recombinant vaccines; vector-based vaccines; DNA/mRNA vaccines; vaccine delivery; adjuvants; vaccine efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Factors Influencing Vaccine Uptake and Immunization Outcomes

edited by Sitong Luo, Meiqi Xin and

Zixin Wang

submission deadline 30 Apr 2026 | 1 articles | Viewed by 539 | Submission Open

Keywords: vaccination; vaccine uptake; immunization

(This special issue belongs to the Section Vaccines and Public Health)

Recent Advances and Strategies for the Management of CIN and HPV Eradication Starategies for the Prevention of Uterine Cervical Cancer

edited by

Masaru Sakamoto

submission deadline 30 Apr 2026 | 1 articles | Viewed by 489 | Submission Open

Keywords: CIN; 9-valent HPV vaccine; HPV L2-VLP vaccine; HPV therapeutic vaccine; endocervical conization; laser vaporization; PDT

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Immunological Responses to mRNA Vaccines

edited by Hyeri Seok

submission deadline 30 Apr 2026 | Viewed by 390 | Submission Open

Keywords: infectious; vaccine; immune response; immunogenicity; vaccine-induced immunity

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 30 Apr 2026 | Viewed by 346 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Oral Vaccines: Challenges, Immunity and Therapeutic Advances

edited by Amin Safa

submission deadline 30 Apr 2026 | Viewed by 298 | Submission Open

Keywords: oral vaccines; mucosal immunity; Peyer’ s patches; nanoparticles; probiotic delivery; cancer immunotherapy; gastrointestinal barriers; antigen presentation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

State of the Art of Flavivirus Virus Research

edited by

Tomoyoshi Komiya

submission deadline 30 Apr 2026 | Viewed by 258 | Submission Open

Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Genetically Engineered Mouse Models in Vaccine Development

edited by Deshan Ren and

Bingqian Qu

submission deadline 30 Apr 2026 | Viewed by 195 | Submission Open

Keywords: vaccine; immunogenicity; knockout; knockin; transgenic mice; humanized mice; xenografts; NCG/NKG/NRG/NSG; viruses

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

New Challenges in Vaccines and Vaccination: A Public Health Perspective

edited by

Marcello Guido

and

Antonella Zizza

submission deadline 30 Apr 2026 | Viewed by 136 | Submission Open

Keywords: vaccine effectiveness/efficacy; vaccination strategies; tailored approaches for different populations; public health

(This special issue belongs to the Section Vaccines and Public Health)

Tumor Vaccines: Current Processes, Prevailing Challenges and Future Perspectives

edited by Xingxing He and Honglin Jin

submission deadline 1 May 2026 | 8 articles | Viewed by 32313 | Submission Open

Keywords: tumor vaccine; mRNA vaccine; personalized medicine; adjuvant; delivery strategies; cancer immunotherapy; personalized vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Exploring Cutaneous Autoimmune Disease Flares in the Wake of COVID-19 Infection and Vaccination

edited by Angeliki-Victoria Roussaki-Schulze, Efterpi Zafiriou and

Emmanouil Karampinis

submission deadline 10 May 2026 | Viewed by 470 | Submission Open

Keywords: COVID-19 infection; COVID-19 vaccination; psoriasis; inflammatory dermatoses; alopecia; bullous dermatoses; adverse reactions; exanthem

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 15 May 2026 | 4 articles | Viewed by 4580 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Treatments Against Viral Hepatitis: Achievements, Challenges and Perspectives, 2nd Edition

edited by

Bárbara Vieira Do Lago

and

Vinicius M. Mello

submission deadline 20 May 2026 | Viewed by 269 | Submission Open

Keywords: vaccination; treatments; viral hepatitis; hepatitis A– E

(This special issue belongs to the Section Hepatitis Virus Vaccines)

Innovative Vaccines and Technologies to Address Tropical Parasitic Diseases

edited by

Cecilia Maria Perez Brandan

Iván Marcipar

and Fernando Sanchez-Valdez

submission deadline 30 May 2026 | Viewed by 216 | Submission Open

Keywords: tropical parasitic diseases; vaccine development; chimeric and multiepitope vaccines; immunomodulation and adjuvants; host– parasite interaction; biotechnology-based vaccine platforms

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccination, Public Health and Epidemiology

edited by

Ricardo Izurieta

submission deadline 31 May 2026 | 9 articles | Viewed by 19469 | Submission Open

Keywords: vaccine; vaccinology; epidemiology; infectious diseases; public health; emerging infectious diseases; tropical neglected diseases

(This special issue belongs to the Section Vaccines and Public Health)

Clinical Strategies to Improve Efficacy, Effectiveness, and Safety of Vaccination in Humans

edited by

Kay Choong See

submission deadline 31 May 2026 | 10 articles | Viewed by 16828 | Submission Open

Keywords: adenovirus vaccines; immunologic adjuvants; adult; communicable diseases; geriatrics; immunocompromised Host; mRNA vaccines; pediatrics; public health; attenuated vaccines; inactivated vaccines

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

A One-Health Perspective on Immunization Against Infectious Diseases

edited by Jose Camilla Sammartino

submission deadline 31 May 2026 | 4 articles | Viewed by 8234 | Submission Open

Keywords: One-Health vaccinology; immunization; vaccine; antibody; infectious disease; emerging pathogens; climate change; sustainability

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Research on HIV/AIDS Vaccine

edited by Portia Chipo Mutevedzi and

Nagesh Kolishetti

submission deadline 31 May 2026 | 3 articles | Viewed by 7308 | Submission Open

Keywords: HIV; antiretroviral treatment (ART); vaccines; drug resistance; vaccine efficacy

(This special issue belongs to the Section HIV Vaccines)

Vaccines to Achieve Affordable Universal Coverage

edited by Pui Hong Chung

submission deadline 31 May 2026 | 2 articles | Viewed by 6899 | Submission Open

Keywords: Sustainable Development Goals (SDGs); global health; vaccines; vaccine equity; vaccine disparities; vaccine accessibility; vaccination literacy; vaccine innovation; disease prevention; vaccine policy and implementation; public health policy; health economics; healthcare disparities; universal health coverage; international health partnerships

(This special issue belongs to the Section Vaccines and Public Health)

Safety and Immunogenicity of Vaccination

edited by Jennifer Serwanga

submission deadline 31 May 2026 | 5 articles | Viewed by 4825 | Submission Open

Keywords: vaccine safety; immunogenicity profiling; correlates of protection; vaccine-induced immunity; dose optimization and adjuvants; breakthrough infections; long-term immune memory; vaccines in special populations

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Vaccine, Preventive Strategies and Antiviral Responses to Zoonotic Viruses

edited by

Wei Ye

, Shu Shen, Chen Peng and Ben Hu

submission deadline 31 May 2026 | 1 articles | Viewed by 2326 | Submission Open

Keywords: alphavirus; arenavirus; bunyavirus; coronavirus; flavivirus; filovirus; orthomyxovirus (e.g.; avian influenza virus); orthopoxvirus; paramyxovirus; rhabdovirus

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy

edited by

Ruchi Roy

submission deadline 31 May 2026 | 1 articles | Viewed by 1645 | Submission Open

Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advances in ImmunoTherapy of Cancer

edited by Li Ye and Jiajun Fan

submission deadline 31 May 2026 | 1 articles | Viewed by 1243 | Submission Open

Keywords: cancer vaccines; neoantigen; immunotherapy; cancer microenviroment

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

SARS-CoV-2 Pathogenesis, Vaccines and Therapeutics

edited by

Hatem A. Elshabrawy

submission deadline 31 May 2026 | 1 articles | Viewed by 806 | Submission Open

Keywords: vaccine; SARS-CoV-2; COVID-19; antibodies; antivirals

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination

edited by

Paul Shing-fong Chan

submission deadline 31 May 2026 | 1 articles | Viewed by 449 | Submission Open

Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Therapeutic Cancer Vaccines: Advances, Challenges, and Future Directions

edited by Erminia Massarelli and Victoria M. Villaflor

submission deadline 31 May 2026 | Viewed by 448 | Submission Open

Keywords: therapeutic cancer vaccines; clinical trials; solid tumors; malignant hematology; peptide vaccines; DNA vaccines; vector vaccines; dendritic cell vaccines; allogenic vaccines; mRNA vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccines Based on Dendritic Cells: Breaking Barriers to New Immune Response Approach

edited by

Soledad Lopez-Enriquez

submission deadline 31 May 2026 | Viewed by 440 | Submission Open

Keywords: plasmacytoid dendritic cells; myeloid dendritic cells; immunotolerance; regulatory T cells; cytotoxic T cells; NK cells; immunotherapies; nanovaccines; immunometabolism; delivery systems

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Recent Research on Adenovirus-Vectored Vaccines

edited by

Michael A. Barry

and

Vijay S. Reddy

submission deadline 31 May 2026 | Viewed by 307 | Submission Open

Keywords: adenovirus; replication competent; single cycle; replication defective; serotypes; targeting; structure; cryo-EM; vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Avian Viruses and the Host Immune System

edited by

Kang Ning

, Junfeng Lv and

Xiujuan Zhang

submission deadline 31 May 2026 | Viewed by 289 | Submission Open

Keywords: avian; waterfowl; viral diseases; vaccination strategies; viral vector development; host immune response

(This special issue belongs to the Section Veterinary Vaccines)

NK Cell-Mediated Immune Responses and Tumor Defense

edited by Dae Joong Kim and Luc Van Kaer

submission deadline 31 May 2026 | Viewed by 274 | Submission Open

Keywords: innate immunity; metastasis; MHC class I; immunotherapy; cytokines; STING; IFNγ ; NK cell engager; CD8 T cell; chimeric antigen receptors (CARs)

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition

edited by

Gang Ye

submission deadline 31 May 2026 | Viewed by 262 | Submission Open

Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Advances in Serologic Assays for Vaccination Monitoring and Assessment of Immune Protection

edited by Paul D. Olivo and Randolph F.R. Rasch

submission deadline 31 May 2026 | Viewed by 262 | Submission Open

Keywords: vaccines; vaccine-preventable diseases; antibodies; serology; correlates of protection; biomarkers of immunity; immunosurveillance

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccines Against Swine Respiratory Diseases

edited by Jairo Jaime

submission deadline 31 May 2026 | Viewed by 169 | Submission Open

Keywords: porcine respiratory disease complex (PRDC); vaccines; innate and adaptive immunity; viruses; bacteria; adjuvants; new vaccination strategies

(This special issue belongs to the Section Veterinary Vaccines)

Evaluating Immunisation Programmes to Optimise Vaccination Strategies and Strengthen Vaccines Impact

edited by Irina Kislaya and Ausenda Machado

submission deadline 31 May 2026 | Viewed by 159 | Submission Open

Keywords: immunisation programme; impact; evaluation; implementation

(This special issue belongs to the Section Epidemiology and Vaccination)

Novel Adjuvants and Delivery Technologies for Vaccine Development

edited by

Mohammad N. Uddin

and

Bernadette D’Souza

submission deadline 31 May 2026 | Viewed by 148 | Submission Open

Keywords: adjuvants; vaccine delivery systems; immunogenicity; nanotechnology; clinical trials; antigen presentation; formulation development; vaccine efficacy; mucosal immunity

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccines and Immune-Modulators for Mammalian Livestock Species

edited by

Falko Steinbach

, Eliane Isabelle Marti,

Cornelia Deeg

and Rupam Dutta

submission deadline 31 May 2026 | Viewed by 139 | Submission Open

Keywords: vaccines; mammalian species; adjuvants; immune-modulators

(This special issue belongs to the Section Veterinary Vaccines)

Advances in Pneumococcal Vaccines: Efficacy, Implementation, and Coverage

edited by Jose María Marimón

submission deadline 31 May 2026 | Viewed by 87 | Submission Open

Keywords: pneumococcal conjugate vaccines; pneumococcal diseases; streptococcus pneumoniae serotypes; serotype replacement

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines for Tuberculosis Control

edited by

Subramanian Dhandayuthapani

and Chinnaswamy Jagannath

submission deadline 15 Jun 2026 | Viewed by 147 | Submission Open

Keywords: tuberculosis vaccine; recombinant vaccines; mRNA vaccines; viral vector vaccines; peptide vaccines; DNA vaccines; live-attenuated vaccines; immunology of adjuvants; immunoinformatics; multi-omics integration

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Innovations in Immunotherapy and Cancer Vaccines: From Bench to Bedside

edited by

Paul Takam Kamga

submission deadline 16 Jun 2026 | 1 articles | Viewed by 884 | Submission Open

Keywords: cancer; immunotherapy; vaccine; preclinical and clinical studies

Peptide-Based Vaccines

edited by

Waleed Hussein

Mariusz Skwarczynski

and Ahmed O. Shalash

submission deadline 30 Jun 2026 | 4 articles | Viewed by 12354 | Submission Open

Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants

Host–Virus Interactions and Vaccine Development

edited by

Masaaki Miyazawa

submission deadline 30 Jun 2026 | 4 articles | Viewed by 11529 | Submission Open

Keywords: virus infection; host genes; immune regulation; innate immunity; immunological memory; vaccine efficacy

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Immunization of Immunosuppressed Patients

edited by

Massimo Franchini

and

Daniele Focosi

submission deadline 30 Jun 2026 | 6 articles | Viewed by 10299 | Submission Open

Keywords: COVID-19; vaccine efficacy; immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Vaccination for Patients with Respiratory Diseases

edited by

Wang Chun Kwok

and

Pin-Kuei Fu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9256 | Submission Open

Keywords: asthma; COPD; bronchiectasis; ILD; vaccines

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

State-of-the-Art Vaccine Design

edited by

D. William Provance, Jr.

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9111 | Submission Open

Keywords: vaccine; adjuvant; recombinant antigen; synthetic biology; vaccine delivery systems; universal vaccines; immunity

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

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