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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy

edited by

Ruchi Roy

submission deadline 31 Oct 2025 | Viewed by 49 | Submission Open

Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Bioengineering in Vaccine Design and Delivery

edited by

Massimo Zollo

submission deadline 1 Nov 2025 | 3 articles | Viewed by 7591 | Submission Open

Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 1 Nov 2025 | 2 articles | Viewed by 3274 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Molecular Virology and Translational Research in Antiviral Vaccine Development

edited by

Safder Ganaie

submission deadline 20 Nov 2025 | Viewed by 148 | Submission Open

Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses

COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition

edited by

Fabrizio Maggi

and

Licia Bordi

submission deadline 30 Nov 2025 | 19 articles | Viewed by 83475 | Submission Open

Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Feature Papers of DNA and mRNA Vaccines

edited by

Jorge H. Leitão

submission deadline 30 Nov 2025 | 9 articles | Viewed by 39574 | Submission Open

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Advance Public Health Through Vaccination

edited by

Gianluca Voglino

, Maria Rosaria Gualano,

Giuseppina Lo Moro

and

Erica De Vita

submission deadline 30 Nov 2025 | 15 articles | Viewed by 27043 | Submission Open

Keywords: epidemiology; vaccination strategies; vaccine hesitancy; health equity; vulnerable population

(This special issue belongs to the Section Vaccines and Public Health)

Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects

edited by

Eyad Elkord

and Afsheen Raza

submission deadline 30 Nov 2025 | 4 articles | Viewed by 8095 | Submission Open

Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7242 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Advanced Concepts in Vaccines in Public Health

edited by

Lamberto Manzoli

and Maria Elena Flacco

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5868 | Submission Open

Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness

(This special issue belongs to the Section Vaccines and Public Health)

The Vaccine Development and Study of Swine Diseases

edited by

Chunhe Guo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1885 | Submission Open

Keywords: swine diseases; viruses; vaccines; protection; control

(This special issue belongs to the Section Veterinary Vaccines)

Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition

edited by Juan Yang and Wei Wang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1727 | Submission Open

Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

New Insights into Vaccination and Public Health: 2nd Edition

edited by

Paolo Castiglia

and

Antonella Arghittu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1336 | Submission Open

Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases

(This special issue belongs to the Section Vaccines and Public Health)

Intracellular Parasites: Immunology, Resistance, and Therapeutics

edited by

Rajesh Mani

and Nagendran Tharmalingam

submission deadline 30 Nov 2025 | Viewed by 1313 | Submission Open

Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Advances in HIV Vaccine Development, 2nd Edition

edited by

Xueling Wu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 832 | Submission Open

Keywords: HIV; envelope glycoprotein; vaccine; adjuvant; antibody; neutralization; ADCC; ADCP; complement; cellular immune response

(This special issue belongs to the Section HIV Vaccines)

Animal Infectious Diseases and Vaccinology in One Health

edited by

Edith Rojas-Anaya

and Elizabeth Loza-Rubio

submission deadline 30 Nov 2025 | 1 articles | Viewed by 762 | Submission Open

Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses

(This special issue belongs to the Section Veterinary Vaccines)

Cost-Effectiveness of Vaccines and Public Health

edited by Sachin A. Silva

submission deadline 30 Nov 2025 | Viewed by 645 | Submission Open

Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Design Against Porcine Circovirus

edited by

Jianli Shi

Junki Maruyama

and

Takeshi Saito

submission deadline 30 Nov 2025 | Viewed by 521 | Submission Open

Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method

(This special issue belongs to the Section Veterinary Vaccines)

Bacterial and Viral Infections: Current Challenges and Vaccine Innovations

edited by Dima El Safadi

submission deadline 30 Nov 2025 | Viewed by 354 | Submission Open

Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination

edited by

Paul Shing-fong Chan

submission deadline 30 Nov 2025 | Viewed by 349 | Submission Open

Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Tuberculosis Diagnosis and Vaccines Research

edited by Shumaila Nida Javed Tunio

submission deadline 30 Nov 2025 | Viewed by 246 | Submission Open

Keywords: developing new diagnostic methods; new drugs; new vaccines for tuberculosis

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition

edited by

Imran Saleem

submission deadline 30 Nov 2025 | Viewed by 86 | Submission Open

Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccines for Porcine Coronaviruses

edited by

Jung-Eun Park

submission deadline 1 Dec 2025 | Viewed by 303 | Submission Open

Keywords: porcine coronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); porcine deltacoronavirus (PDCoV); swine acute diarrhea syndrome coronavirus (SADS-CoV); porcine respiratory coronavirus (PRCV); porcine hemagglutinating encephalomyelitis virus (PHEV); vaccine; immune response; protective efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Public Health in the 21st Century

edited by

Evridiki Patelarou

Enkeleint A. Mechili

and

Athina E. Patelarou

submission deadline 20 Dec 2025 | 7 articles | Viewed by 7534 | Submission Open

Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development

(This special issue belongs to the Section Vaccines and Public Health)

Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

edited by Wandi Zhu

submission deadline 20 Dec 2025 | Viewed by 203 | Submission Open

Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity

Human Immune Responses to Infection and Vaccination

edited by

Alexander Batista-Duharte

and Gabriel Cabrera

submission deadline 31 Dec 2025 | 6 articles | Viewed by 10028 | Submission Open

Keywords: vaccine immunogenicity; adjuvants; new generation of vaccines; vaccine development; immune regulation; translational vaccinology; system vaccinology; herd immunity; vaccine safety; correlates of protection

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19

edited by

Roland Zahn

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7456 | Submission Open

Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Health Technology Assessment of Vaccination: Strategies, Public Health and Values

edited by Maarten J. Postma, Jurjen Van der Schans and

Cornelis Boersma

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7198 | Submission Open

Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Against Poultry Viruses

edited by

Xiuli Feng

submission deadline 31 Dec 2025 | 2 articles | Viewed by 6063 | Submission Open

Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs

(This special issue belongs to the Section Veterinary Vaccines)

Recent Scientific Advances in Vaccines for Shigella

edited by Akamol Suvarnapunya, Kristen A Clarkson, Renee Laird and August Louis Bourgeois

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3919 | Submission Open

Keywords: Shigella; vaccines; global health

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Strategies for the Monitoring, Treatment, and Prevention of Mpox and Other Poxvirus Infections

edited by Patrick Obermeier and Susanne Buder

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3689 | Submission Open

Keywords: poxvirus; mpox; emerging infection; epidemiology; surveillance; vaccine; vaccine efficacy; immunity; one health; global health

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for the Vulnerable Population

edited by

My Kieu Ha

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3203 | Submission Open

Keywords: vaccines; vulnerable populations; infectious diseases; immunization

(This special issue belongs to the Section Vaccines and Public Health)

Prevention of Human Papillomavirus (HPV) and Vaccination

edited by

Sara Boccalini

Paolo Bonanni

and

Angela Bechini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3101 | Submission Open

Keywords: HPV vaccination; screening; PAP test; HPV-DNA test; HPV vaccine coverage; vaccine hesitancy; promotion

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Cutting-Edge Cancer Vaccines Enhanced by Nanotechnology

edited by

Xiupeng Wang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2958 | Submission Open

Keywords: cancer immunotherapy; nanotechnology; cancer vaccine; adjuvant; in situ cancer vaccine; personalized cancer vaccine; combination cancer therapy; nanoparticle

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Strategies to Enhance Vaccine Uptake and Immunization Among Underserved Populations/Vulnerable Groups

edited by

Álvaro Francisco Lopes De Sousa

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2815 | Submission Open

Keywords: vaccine uptake; vulnerable populations; health interventions; vaccine hesitancy; public health strategies; health education and equity

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines and Antibody-Based Therapeutics Against Infectious Disease

edited by Suman Kundu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2526 | Submission Open

Keywords: infectious disease; vaccine; antibody; therapy; agriculture; protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

The Development of mRNA Vaccines

edited by Minghui Yang, Yuming Li and Bo Hu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2347 | Submission Open

Keywords: nanoparticle delivery system; mRNA vaccines; infectious disease; tumor immunity; adjuvant

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Vaccination and Public Health Strategy

edited by Shenglan Tang, Lance E. Rodewald and Taufique Joarder

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2304 | Submission Open

Keywords: immunization Agenda 2030; vaccine equity; new vaccines introduction; sustainable immunization and financing; sustainable vaccine supply and procurement

(This special issue belongs to the Section Vaccines and Public Health)

Vaccine and Vaccination in Veterinary Medicine

edited by

Diqiu Liu

and Wen Shi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2048 | Submission Open

Keywords: veterinary vaccine; vaccine design; vaccine safety and efficacy; immune response; immunization

(This special issue belongs to the Section Veterinary Vaccines)

The Development of Vaccine Against Parasite Infection

edited by

Kathryn M. Jones

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1679 | Submission Open

Keywords: adaptive immune response; vaccine; adjuvant; protozoal; helminth; apicomplexan; delivery systems; epidemiology; needs assessment

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Strategies for HPV-Related Cancers: 2nd Edition

edited by

Diane M. Harper

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1462 | Submission Open

Keywords: HPV vaccine uptake; single dose immunization; clinical unmasking; HPV-associated cancers

(This special issue belongs to the Section Human Papillomavirus Vaccines)

SARS-CoV-2, Influenza and Other Respiratory Viruses: Preventive Measures Affecting the Determinants of Health and Disease

edited by

Marco Del Riccio

and

Saverio Caini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1284 | Submission Open

Keywords: respiratory; viruses; SARS-CoV-2; human influenza; respiratory syncytial virus; vaccines; vaccination strategies; disease burden

(This special issue belongs to the Section Epidemiology and Vaccination)

Epidemiology of Diseases Preventable by Vaccination

edited by

Caterina Elisabetta Rizzo

Cristina Genovese

and

Roberto Venuto

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1215 | Submission Open

Keywords: vaccine safety and efficacy; vaccination strategies; epidemiological surveillance; vaccine equity; disease burden and impact

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccination or Infection and the Role of T Cells—the Response to Cancer, Autoimmunity or Inflammatory Diseases

edited by Yuedan Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1169 | Submission Open

Keywords: T-cell biology; cancer immunotherapy; autoimmune diseases; inflammatory diseases; immune modulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

HPV Vaccination and Primary HPV Screening

edited by

Antonio Di Lorenzo

and

Pasquale Stefanizzi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 765 | Submission Open

Keywords: sexually transmitted diseases; HPV vaccination; cervical cancer screening; vaccine hesitancy; vaccine safety; vaccine effectiveness

(This special issue belongs to the Section Human Papillomavirus Vaccines)

The Development of HIV Vaccines: Advances and Challenges

edited by

Michael Bukrinsky

submission deadline 31 Dec 2025 | 1 articles | Viewed by 756 | Submission Open

Keywords: HIV vaccine; trained immunity; broadly neutralizing antibodies; T-cell immunity; epigenetic reprogramming; immune metabolism; systems immunology; adjuvants; mucosal immunity

(This special issue belongs to the Section HIV Vaccines)

Protective Immunity and Adjuvant Vaccines

edited by

Chengli Zong

submission deadline 31 Dec 2025 | 1 articles | Viewed by 642 | Submission Open

Keywords: protective immunity; adjuvant vaccines; viral diseases; innate immune response; adaptive immune response; vaccine efficacy

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Animal Herpesviruses: 2nd Edition

edited by

Stefano Petrini

and

Clinton Jones

submission deadline 31 Dec 2025 | 1 articles | Viewed by 621 | Submission Open

Keywords: herpesvirus pathogenesis; immune responses; diagnostic tools; herpesvirus vaccinology

(This special issue belongs to the Section Veterinary Vaccines)

Innovative Technology in Vaccine Development: Advancing Immunization Strategies

edited by Aziz Chentoufi

submission deadline 31 Dec 2025 | Viewed by 391 | Submission Open

Keywords: vaccine; mRNA; viral vectors; nanoparticle; structural vaccinology; artificial intelligence; immunization

Vaccination Against Viral Hepatitis for Prevention and Treatment

edited by Antony Black and Monique Andersson

submission deadline 31 Dec 2025 | Viewed by 342 | Submission Open

Keywords: viral hepatitis; vaccines; coverage; epidemiology; immunology; efficacy

(This special issue belongs to the Section Hepatitis Virus Vaccines)

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