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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cutting-Edge Cancer Vaccines Enhanced by Nanotechnology

edited by

Xiupeng Wang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3254 | Submission Open

Keywords: cancer immunotherapy; nanotechnology; cancer vaccine; adjuvant; in situ cancer vaccine; personalized cancer vaccine; combination cancer therapy; nanoparticle

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccination and Public Health Strategy

edited by Shenglan Tang, Lance E. Rodewald and Taufique Joarder

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3128 | Submission Open

Keywords: immunization Agenda 2030; vaccine equity; new vaccines introduction; sustainable immunization and financing; sustainable vaccine supply and procurement

(This special issue belongs to the Section Vaccines and Public Health)

SARS-CoV-2, Influenza and Other Respiratory Viruses: Preventive Measures Affecting the Determinants of Health and Disease

edited by

Marco Del Riccio

and

Saverio Caini

submission deadline 31 Dec 2025 | 4 articles | Viewed by 2946 | Submission Open

Keywords: respiratory; viruses; SARS-CoV-2; human influenza; respiratory syncytial virus; vaccines; vaccination strategies; disease burden

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccine and Vaccination in Veterinary Medicine

edited by

Diqiu Liu

and Wen Shi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2651 | Submission Open

Keywords: veterinary vaccine; vaccine design; vaccine safety and efficacy; immune response; immunization

(This special issue belongs to the Section Veterinary Vaccines)

The Development of Vaccine Against Parasite Infection

edited by

Kathryn M. Jones

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2514 | Submission Open

Keywords: adaptive immune response; vaccine; adjuvant; protozoal; helminth; apicomplexan; delivery systems; epidemiology; needs assessment

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Epidemiology of Diseases Preventable by Vaccination

edited by

Caterina Elisabetta Rizzo

Cristina Genovese

and

Roberto Venuto

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2022 | Submission Open

Keywords: vaccine safety and efficacy; vaccination strategies; epidemiological surveillance; vaccine equity; disease burden and impact

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccine Strategies for HPV-Related Cancers: 2nd Edition

edited by

Diane M. Harper

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1980 | Submission Open

Keywords: HPV vaccine uptake; single dose immunization; clinical unmasking; HPV-associated cancers

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccination or Infection and the Role of T Cells—the Response to Cancer, Autoimmunity or Inflammatory Diseases

edited by Yuedan Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1620 | Submission Open

Keywords: T-cell biology; cancer immunotherapy; autoimmune diseases; inflammatory diseases; immune modulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

The Immunology of Dengue, Chikungunya and Zika Virus: Implications for Vaccines and Vaccine Development

edited by

Jonathan O. Rayner

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1396 | Submission Open

Keywords: dengue; chikungunya; Zika; mosquito; saliva; immunity; innate; adaptive; immunomodulation; vaccines

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Protective Immunity and Adjuvant Vaccines

edited by

Chengli Zong

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1069 | Submission Open

Keywords: protective immunity; adjuvant vaccines; viral diseases; innate immune response; adaptive immune response; vaccine efficacy

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

HPV Vaccination and Primary HPV Screening

edited by

Antonio Di Lorenzo

and

Pasquale Stefanizzi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1036 | Submission Open

Keywords: sexually transmitted diseases; HPV vaccination; cervical cancer screening; vaccine hesitancy; vaccine safety; vaccine effectiveness

(This special issue belongs to the Section Human Papillomavirus Vaccines)

The Development of HIV Vaccines: Advances and Challenges

edited by

Michael Bukrinsky

submission deadline 31 Dec 2025 | 1 articles | Viewed by 965 | Submission Open

Keywords: HIV vaccine; trained immunity; broadly neutralizing antibodies; T-cell immunity; epigenetic reprogramming; immune metabolism; systems immunology; adjuvants; mucosal immunity

(This special issue belongs to the Section HIV Vaccines)

Animal Herpesviruses: 2nd Edition

edited by

Stefano Petrini

and

Clinton Jones

submission deadline 31 Dec 2025 | 1 articles | Viewed by 948 | Submission Open

Keywords: herpesvirus pathogenesis; immune responses; diagnostic tools; herpesvirus vaccinology

(This special issue belongs to the Section Veterinary Vaccines)

Role of Human Papillomavirus Vaccines in Cervical and Vulvo-Vaginal Diseases

edited by

Ignacio Zapardiel

submission deadline 31 Dec 2025 | 1 articles | Viewed by 801 | Submission Open

Keywords: human papillomavirus; preinvasive lesions; vulvar disease; cervical intraepithelial neoplasia; vaginal neoplasia

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Innovative Technology in Vaccine Development: Advancing Immunization Strategies

edited by Aziz Chentoufi

submission deadline 31 Dec 2025 | Viewed by 465 | Submission Open

Keywords: vaccine; mRNA; viral vectors; nanoparticle; structural vaccinology; artificial intelligence; immunization

Vaccination Against Viral Hepatitis for Prevention and Treatment

edited by Antony Black and Monique Andersson

submission deadline 31 Dec 2025 | Viewed by 381 | Submission Open

Keywords: viral hepatitis; vaccines; coverage; epidemiology; immunology; efficacy

(This special issue belongs to the Section Hepatitis Virus Vaccines)

Animal Virus Infection, Immunity and Vaccines: 2nd Edition

edited by

Hani Boshra

submission deadline 31 Dec 2025 | Viewed by 371 | Submission Open

Keywords: zoonotic and veterinary diseases; viruses; vaccinology; immunology

(This special issue belongs to the Section Veterinary Vaccines)

T and B Cell Responses to HIV and Tuberculosis Infections/Coinfection and Vaccinations

edited by

Guohua Yi

submission deadline 31 Dec 2025 | Viewed by 354 | Submission Open

Keywords: T cells; B cells; viral infection; vaccination; vaccine development; immunity; vaccine efficacy

(This special issue belongs to the Section HIV Vaccines)

Vaccines and Other Prophylactic Interventions Against H5N1 Influenza Viruses

edited by Ahmed Mostafa,

Aitor Nogales

and

Luis Martinez-Sobrido

submission deadline 31 Dec 2025 | Viewed by 318 | Submission Open

Keywords: avian influenza; H5N1 viruses; immunity; second-generation vaccines; vaccine effectiveness; adjuvants and immunomodulators; influenza vaccine limitations; vaccine efficacy; vaccine prevention policies

(This special issue belongs to the Section Influenza Virus Vaccines)

African Swine Fever Virus Vaccine Development

edited by

Faming Miao

, Hong Jia and

Lian-Feng Li

submission deadline 31 Dec 2025 | Viewed by 289 | Submission Open

Keywords: African swine fever virus; infection and damage; immune response; vaccine

(This special issue belongs to the Section Veterinary Vaccines)

The Development of Ebolavirus Vaccines and Immunotherapeutics

edited by Kyle L. O'Donnell

submission deadline 31 Dec 2025 | Viewed by 286 | Submission Open

Keywords: Ebola; immunotherapeutics; vaccine platforms; immunogenicity; animal studies

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Viral Vector-Based Vaccines

edited by Marija Zaric, Hilary Whitworth and Arianna Marini

submission deadline 31 Dec 2025 | Viewed by 238 | Submission Open

Keywords: viral vectors; vaccines; immune response; vaccine platforms; vaccine development; vaccine production; vaccine delivery; vaccine safety; infectious disease; cancer vaccines; humoral immunity; cellular immunity; preclinical studies; clinical trials

Immune-Mediated Diseases Following Vaccination

edited by

Giampiero Girolomoni

submission deadline 31 Dec 2025 | Viewed by 159 | Submission Open

Keywords: immune-mediated diseases; autoimmune diseases; atopic dermatitis; asthma; rheumatic diseases; vasculitis

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Recent Advances in Virus-Like Particle-Based Vaccines

edited by

Abel Gutiérrez-Ortega

submission deadline 31 Dec 2025 | Viewed by 153 | Submission Open

Keywords: virus-like particles (VLPs); vaccine design; immune response mechanisms; clinical trials; therapeutic vaccines; vaccine manufacturing; antigen delivery; rapid vaccine development

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Development of Broadly Protective Vaccines Against Respiratory Virus Infections

edited by

Noopur Bhatnagar

and Jerry W. Simecka

submission deadline 20 Jan 2026 | Viewed by 243 | Submission Open

Keywords: broadly protective vaccines; respiratory viruses; universal vaccines; cross-protective immunity; vaccine development; mucosal immunity; T-cell responses; broadly neutralizing antibodies; immunogenicity; vaccine efficacy

Maternal Vaccination and Vaccines

edited by

Gianluca Straface

submission deadline 31 Jan 2026 | 5 articles | Viewed by 19071 | Submission Open

Keywords: prenatal care; vaccination; vaccination hesitancy; Tdap vaccine; influenza vaccine; COVID-19 vaccine

(This special issue belongs to the Section Vaccines and Public Health)

Prevention of Human Papillomavirus and Vaccines Strategies

edited by

Rui Gil da Costa

submission deadline 31 Jan 2026 | 5 articles | Viewed by 18468 | Submission Open

Keywords: human papillomavirus; HPV vaccines; vaccination strategies; cervical cancer prevention; therapeutic vaccines

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccines and Vaccination: HIV, Hepatitis Viruses, and HPV

edited by

Ivan Schietroma

and

Sonia Moretti

submission deadline 31 Jan 2026 | 8 articles | Viewed by 15037 | Submission Open

Keywords: preventative vaccine; therapeutic vaccine; HIV; hepatitis A; hepatitis B; human papillomavirus; sexually transmitted infections; immunoprotection; vaccination; preventable diseases

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Fish Disease Occurrence and Immune Prevention and Control

edited by

Yonghua Hu

Jianmin Ye

and Yang Zhou

submission deadline 31 Jan 2026 | 4 articles | Viewed by 13253 | Submission Open

Keywords: fish immunology; fish disease; pathogenesis; virulence factor; disease prevention and control; vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Virus-Like Particle Vaccine Development

edited by

Jian Xu

submission deadline 31 Jan 2026 | 6 articles | Viewed by 12380 | Submission Open

Keywords: vaccine; virus-like particle; display; protein production; immunogenicity

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Innovations in Vaccine Technology

edited by

Rachel Stephenson

submission deadline 31 Jan 2026 | 8 articles | Viewed by 11926 | Submission Open

Keywords: inactivated vaccines; live-attenuated vaccines; messenger RNA (mRNA) vaccines; subunit; recombinant; polysaccharide and conjugate vaccines; toxoid vaccines; viral vector vaccines; personalized vaccines; antigen design; reverse vaccinology; lipid nanoparticles; cell-based vaccine production; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunity to Influenza Viruses and Vaccines

edited by

Rongbao Gao

submission deadline 31 Jan 2026 | 6 articles | Viewed by 10084 | Submission Open

Keywords: avian influenza; etiology; antiviral immunity; serology; vaccine; pathogenesis

(This special issue belongs to the Section Influenza Virus Vaccines)

Analysis of Vaccine-Induced Adaptive Immune Responses

edited by

Francesco Nicoli

and

Antonella Caputo

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8981 | Submission Open

Keywords: RNA sequencing; flow cytometry; microscopy; T cells; B cells; antibodies; biochemistry; molecular biology; systems biology; epitope prediction

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Next-Generation Vaccine and Immunotherapy

edited by

Takashi Imai

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8890 | Submission Open

Keywords: next-generation vaccine; immunotherapy; pathogens; cancers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Recent Scientific Development of Poliovirus Vaccines

edited by

Lester M. Shulman

submission deadline 31 Jan 2026 | 5 articles | Viewed by 7950 | Submission Open

Keywords: novel oral polio vaccines (nOPV); vaccine-derived poliovirus (VDPV); recombination; inactivated oral vaccine strains (sIPV); edible vaccines; non-infectious vaccine-like particles (VLPs); subdermal administration of fractional doses; adjuvants; edible vaccines; microarray patches

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Development and Global Health

edited by

Anna Paczkowska

Karolina Hoffmann

and

Krzysztof Kus

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6050 | Submission Open

Keywords: next-generation vaccines; clinical efficacy of vaccines; vaccine safety; treatment methods for civilization diseases; public health; prevention of civilization diseases

(This special issue belongs to the Section Vaccines and Public Health)

Respiratory Viruses and Antiviral Immunity

edited by

Andreu Comas-Garcia

Sofía Bernal-Silva

and

Maria Grazia Cusi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 4729 | Submission Open

Keywords: respiratory viruses; innate antiviral response; adaptative antiviral response; prevention; damage; viral clearance

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Immune Responses in Patients with Inflammatory Bowel Disease After Vaccination

edited by

Phil-Robin Tepasse

and Arne Bokemeyer

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3749 | Submission Open

Keywords: inflammatory bowel disease; vaccination; opportunistic infections; immune response; immunomodulatory therapy

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Effectiveness and Safety of Vaccines in Special Populations

edited by Arjan Harxhi and

Justyna Dominika Kowalska

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3665 | Submission Open

Keywords: vaccines; special populations; HIV; pregnancy; migrants

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Advances in Vaccine Adjuvants

edited by Devyani Joshi and Sanjeev Kumar

submission deadline 31 Jan 2026 | 5 articles | Viewed by 3636 | Submission Open

Keywords: infectious diseases; cancer vaccines; mechanisms of adjuvants; novel adjuvants; delivery systems; particulate adjuvants; innate immune response; adaptive immune response

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Development of Novel Mucosal Vaccines: Advances in Technology and Delivery

edited by

Mohamed I. Husseiny El-Sayed

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3054 | Submission Open

Keywords: oral vaccines; nasal vaccines; live attenuated vaccines; DNA vaccines; mRNA vaccines; viral vectors vaccine; nanoparticle delivery system; adjuvants; gene-based vaccine; microencapsulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Challenges to Developing New Vaccines and Improving Existing Platforms

edited by

S. Louise Cosby

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2962 | Submission Open

Keywords: infectious disease; cancer vaccines; humoral and cellular immunity; flaviviruses vaccines; inactivated and subunit vaccines; novel assays

Novel Immunotherapies, Cell Therapies and Cancer Vaccines

edited by

Vita Golubovskaya

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2150 | Submission Open

Keywords: cell therapy; vaccine; cancer; immunotherapy; antibody

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccination Against Major Respiratory Pathogens in Livestock Farming

edited by

Enrico Brugnera

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1994 | Submission Open

Keywords: respiratory tract infections; innate and adaptive immune responses; vaccines; safety issues; risks and benefits studies

(This special issue belongs to the Section Veterinary Vaccines)

Host Immunity and Vaccines for Respiratory Pathogens

edited by

Hanqing He

and

Yuxia Liang

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1421 | Submission Open

Keywords: vaccines; immunity; infectious disease; respiratory pathogens

Vaccines for Porcine Diseases

edited by Xiaohu Wang and

Lizette M. Cortes

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1127 | Submission Open

Keywords: vaccine development; immune mechanisms; adjuvants; global animal health; porcine diseases; vaccine candidate targets

(This special issue belongs to the Section Veterinary Vaccines)

Recent Research on Human Papillomavirus (HPV) Infection and Vaccination: 2nd Edition

edited by

Li Shi

and Yufeng Yao

submission deadline 31 Jan 2026 | 1 articles | Viewed by 996 | Submission Open

Keywords: HPV infection; HPV vaccination; willingness; hesitancy; therapeutic vaccines; cervical cancer prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccine Design and Development

edited by

Vladimir Temchura

submission deadline 31 Jan 2026 | 2 articles | Viewed by 772 | Submission Open

Keywords: vaccine design; vaccine development; vaccinology; immunization; immune response; vaccine delivery; vaccine efficacy

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immune Responses After Malaria Infection and Next Generation Malaria Vaccine

edited by Yu-Min Chuang

submission deadline 31 Jan 2026 | Viewed by 408 | Submission Open

Keywords: humoral immune response; cellular immune response; malaria; antimalaria vaccine; Plasmodium

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Chronic Viral Infections and Cancer: Openings for Vaccines and Cure

edited by

Maria G. Isaguliants

and Karl Ljungberg

submission deadline 31 Jan 2026 | Viewed by 316 | Submission Open

Keywords: chronic viral infection; oncogenic viruses; hepatitis B virus; high risk human papillomaviruses; hepatitis C virus; epstein– barr virus; human immunodeficiency virus type I; cancer associated with viral infection; immunotherapy; prophylactic viral vaccines; therapeutic viral vaccines

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