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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing the Science on Vaccine Hesitancy to Inform Interventions

edited by Kimberly H. Nguyen and

Jennifer Allen

submission deadline 31 Aug 2025 | 6 articles | Viewed by 9668 | Submission Open

Keywords: vaccine hesitancy; vaccine confidence; COVID-19; routinely recommended vaccines; epidemiologic methods; conceptual frameworks; strategies; surveillance

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines Targeting the Tumor Microenvironment: Challenges and Future Prospects

edited by

Walter J. Storkus

and Devin Lowe

submission deadline 31 Aug 2025 | 6 articles | Viewed by 9577 | Submission Open

Keywords: vaccine; adoptive cell therapy; CAR-T cells; immune checkpoint inhibitors; immunotherapy; stroma; tumor microenvironment

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Advances in Glycoconjugate Vaccines and Nanovaccines

edited by

Marco Terreni

and

Sara Tengattini

submission deadline 31 Aug 2025 | 4 articles | Viewed by 8822 | Submission Open

Keywords: glycoconjugate vaccines; infection diseases; anticancer vaccines; glycosylated nanovaccines; antigenic saccharides; conjugation chemistry; glycoconjugate characterization; dual-acting vaccines; glycosylated nanoparticles

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Respiratory Syncytial Virus (RSV) Vaccine

edited by

Surender Khurana

submission deadline 31 Aug 2025 | 3 articles | Viewed by 5400 | Submission Open

Keywords: respiratory syncytial virus (RSV); RSV vaccine development; viral vector vaccines; subunit vaccines; prefusion protein design; mRNA vaccines; vaccine efficacy; immunization strategies

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Role of Gut Microbiota in Immune Tolerance and Vaccine Development

edited by

Sin-Hyeog Im

submission deadline 31 Aug 2025 | 2 articles | Viewed by 4862 | Submission Open

Keywords: immune tolerance; subtype of immune cells; microbiome; probiotics; T cells; B cells; dendritic cells; antigen-presenting cells

(This special issue belongs to the Section Clinical Immunology)

Vaccine Hesitancy and Acceptance: A Public Health Perspective

edited by

Neli Ragina

and

Michael J. Conway

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1302 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; public health; vaccine uptake; misinformation; risk perception; health communication; immunization rates; herd immunity; behavioral determinants; social determinants; trust in healthcare; vaccine misinformation; vaccine education; vaccine refusal; vaccine policy; health disparities

(This special issue belongs to the Section Human Vaccines and Public Health)

Understanding Infectious Disease Vaccinations: Implications for Health and Safety

edited by

Daniel Kwasi Ahorsu

submission deadline 31 Aug 2025 | 1 articles | Viewed by 671 | Submission Open

Keywords: vaccination; infectious disease; health; wellbeing; knowledge; attitudes

(This special issue belongs to the Section Human Vaccines and Public Health)

Strategies for Addressing Vaccine Hesitancy

edited by

Donald J. Alcendor

submission deadline 31 Aug 2025 | Viewed by 560 | Submission Open

Keywords: vaccines; vaccine hesitancy; vaccine uptake; vaccine misinformation; vaccine disparities

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition

edited by

Arturo Reyes-Sandoval

and

Young Chan Kim

submission deadline 31 Aug 2025 | 1 articles | Viewed by 473 | Submission Open

Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

The 2nd Edition: Non-Specific Protection in the Response to Vaccination and Other Immune Stimulation

edited by

François Meurens

Fanny Renois

and

Jianzhong Zhu

submission deadline 31 Aug 2025 | Viewed by 414 | Submission Open

Keywords: non-specific protections; vaccination; non-specific effects (NSEs); trained immunity; immune system; pathogens

(This special issue belongs to the Section Pathogens-host Immune Interface)

Studies of Infectious Disease Epidemiology and Vaccination

edited by

Jose Gonzales-Zamora

and Shweta Anjan

submission deadline 31 Aug 2025 | Viewed by 328 | Submission Open

Keywords: vaccine effectiveness; vaccination policies; cost-effectiveness; surveillance; public health; high-risk population; infectious diseases

(This special issue belongs to the Section Epidemiology)

Childhood Immunization and Public Health

edited by Carsten Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 317 | Submission Open

Keywords: compulsory/mandatory vaccination; coverage; local vaccination culture; pandemics; trust; vaccination frameworks; vaccine equity; vaccine hesitancy; zero-dose

(This special issue belongs to the Section Human Vaccines and Public Health)

Vaccination Against Vector-Borne Diseases: Bridging Public Health and Epidemiology

edited by

Angela Stufano

and

Claudia Maria Trombetta

submission deadline 31 Aug 2025 | Viewed by 294 | Submission Open

Keywords: vector-borne diseases; vaccination strategies; epidemiology; public health integration; disease prevention

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccination Advances for HBV, HPV, and Influenza

edited by

Wangnan Cao

submission deadline 31 Aug 2025 | Viewed by 243 | Submission Open

Keywords: HBV; HPV; influenza; vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 31 Aug 2025 | Viewed by 208 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Modulating CD4+ T Cells for Cancer Immunotherapy: Emerging Strategies and Applications

edited by

Haval Shirwan

submission deadline 1 Sep 2025 | 2 articles | Viewed by 4334 | Submission Open

Keywords: CD4+ T cells; immunomodulation; cancer immunotherapy; cancer vaccines; immunotherapeutic agents

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Virus Pandemics and Vaccinations

edited by Renata Gili,

Davide Gori

and

Matteo Riccò

submission deadline 1 Sep 2025 | 2 articles | Viewed by 2573 | Submission Open

Keywords: vaccine; vaccination strategy; one health; emerging pathogens; vaccine hesitancy

(This special issue belongs to the Section Human Vaccines and Public Health)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 1 Sep 2025 | Viewed by 271 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Maternal and Infant Vaccines

edited by Prabha Andraweera and Bing Wang

submission deadline 20 Sep 2025 | Viewed by 111 | Submission Open

Keywords: maternal vaccines; infant vaccines; immunogenicity; effectiveness; vaccine uptake; safety

Vaccination Strategies for Global Public Health

edited by

Mathumalar Fahrni

and

Antonio Ivan Lazzarino

submission deadline 30 Sep 2025 | 12 articles | Viewed by 25352 | Submission Open

Keywords: emerging infectious disease; SARS-CoV-2; human monkeypox; dengue; henipavirus; public health; population-based studies; modelling; social impact; equitable access; vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Sep 2025 | 9 articles | Viewed by 16901 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Peptide-Based Vaccines

edited by

Waleed Hussein

Mariusz Skwarczynski

and Ahmed O. Shalash

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5377 | Submission Open

Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants

Role of Next Generation Vaccines in Immunotherapeutics

edited by Swayam Prakash

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5036 | Submission Open

Keywords: immunotherapeutics; vaccines; nucleic acid vaccines; viral vector and protein subunit vaccines; cancer vaccines; autoimmune diseases and allergies; COVID-19; clinical trials; pre-clinical trials

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4208 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Development of Vaccines against Bacterial Infections

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1948 | Submission Open

Keywords: novel vaccine formulations; bacterial pathogenesis mechanisms; immunogenicity assessment; vaccine efficacy studies; next-generation vaccine platforms; targeted antigen design; novel adjuvants; vaccine clinical trials; vaccine delivery systems; vaccine cross-protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Hesitancy and Acceptance

edited by Karl Hess, Jeff Goad and Laressa Bethishou

submission deadline 30 Sep 2025 | 1 articles | Viewed by 756 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; barriers to vaccination; vaccination strategies

(This special issue belongs to the Section Human Vaccines and Public Health)

Hepatitis Vaccines: Safety, Efficacy and Global Impact

edited by

Muhammad Atif Zahoor

submission deadline 30 Sep 2025 | 1 articles | Viewed by 622 | Submission Open

Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges

(This special issue belongs to the Section Hepatitis Virus Vaccines)

3rd Edition: Safety and Autoimmune Response to SARS-CoV-2 Vaccination

edited by

Minghui Yang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 517 | Submission Open

Keywords: COVID-19 vaccine; vaccine efficacy; vaccine safety; adverse events following immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Vaccine Hesitancy in the Era of COVID-19

edited by

and

submission deadline 30 Sep 2025 | Viewed by 458 | Submission Open

Keywords: vaccine hesitancy; evidence synthesis; COVID-19

(This special issue belongs to the Section Human Vaccines and Public Health)

Animal Vaccines: 2nd Edition

edited by

Hsian-Yu Wang

and

David Benfield

submission deadline 30 Sep 2025 | Viewed by 292 | Submission Open

Keywords: animal vaccines; novel antigen or adjuvant design; vaccine technologies

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Against Sexually Transmitted Diseases

edited by Weiming Tang

submission deadline 30 Sep 2025 | Viewed by 261 | Submission Open

Keywords: vaccination; sexually transmitted infections; HPV; HIV; syphilis; gonorrhea; and chlamydia; vaccine development; public health; epidemiology; health equity; preventive strategies

(This special issue belongs to the Section HIV Vaccines)

Bioengineering Strategies for Developing Vaccines

edited by Chen Zhao and Jiayi Shu

submission deadline 30 Sep 2025 | Viewed by 257 | Submission Open

Keywords: vaccine platform; antigen design; targeted delivery; mRNA; nanoparticle; artificial intelligence

Innovations in Immunotherapy: Advancements in Cancer Vaccines and Immune Modulation

edited by

Nan Zhang

and

Hao Zhang

submission deadline 30 Sep 2025 | Viewed by 189 | Submission Open

Keywords: multi-omics; cancer therapy; precision medicine; cancer vaccines

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition

edited by

Gang Ye

submission deadline 30 Sep 2025 | Viewed by 132 | Submission Open

Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines

(This special issue belongs to the Section Vaccine Adjuvants)

Oral and Nucleic Acid Vaccines for Zoonotic and Animal Infectious Diseases

edited by Lei Shuai

submission deadline 30 Sep 2025 | Viewed by 96 | Submission Open

Keywords: oral vaccines; nucleic acid vaccines; zoonotic diseases; animal infectious diseases; vaccine development; vaccine safety; vaccine efficacy; immunological mechanism

(This special issue belongs to the Section Veterinary Vaccines)

Factors Affecting Influenza Vaccine Uptake

edited by

Adriana Pistol

submission deadline 20 Oct 2025 | Viewed by 929 | Submission Open

Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups

(This special issue belongs to the Section Influenza Virus Vaccines)

Viral Vector-Based and Other Vaccine Strategies for Poultry and Livestock

edited by Mathias Martins

submission deadline 20 Oct 2025 | Viewed by 324 | Submission Open

Keywords: vaccine strategies; viral vector-based vaccines; poultry; livestock; infectious diseases; immune responses; vaccine platforms; genetic engineering; veterinary medicine; antigen delivery

(This special issue belongs to the Section Veterinary Vaccines)

New Technology for Vaccines and Vaccine-Preventable Diseases

edited by

Jue Liu

submission deadline 20 Oct 2025 | Viewed by 226 | Submission Open

Keywords: artificial intelligence in vaccines; big data in vaccine research; emerging infectious diseases; vaccine accessibility; vaccine delivery systems; vaccine efficacy and safety; vaccine-preventable diseases; vaccine technology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines Against Influenza and Other Respiratory Virus Infections

edited by

Santosh Dhakal

submission deadline 20 Oct 2025 | Viewed by 116 | Submission Open

Keywords: adjuvants; influenza; mucosal immunity; respiratory viral pathogens; vaccine effectiveness; vaccine safety

(This special issue belongs to the Section Influenza Virus Vaccines)

Immunization Strategies for Animal Health

edited by Eva Calvo-Pinilla and

Alejandro Marin-Lopez

submission deadline 31 Oct 2025 | 6 articles | Viewed by 13718 | Submission Open

Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination

(This special issue belongs to the Section Veterinary Vaccines)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7064 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)

Next-Generation Vaccines for Animal Infectious Diseases

edited by Yongwen Luo, Huiying Fan and Qing Wang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5948 | Submission Open

Keywords: LNP-mRNA vaccines; VLP vaccines; polymeric/inorganic nanoparticle vaccines; self-assembled protein vaccines; biomimetic nanoparticle vaccines; novel vector-based vaccines; new adjuvanted vaccines; nanovaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Development for Swine Viral Pathogens

edited by Qingli Niu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5021 | Submission Open

Keywords: vaccine engineering; design; formulation; adjuvants; delivery; testing

(This special issue belongs to the Section Veterinary Vaccines)

Animal Diseases: Immune Response and Vaccines

edited by

Verónica Martín

, José M. Rojas and

Noemí Sevilla

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4918 | Submission Open

Keywords: immune responses; ruminants; vaccines; animal health

(This special issue belongs to the Section Veterinary Vaccines)

Humoral and Cellular Response after Vaccination

edited by Adrian Onu and Iuliana Caras

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4505 | Submission Open

Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus

(This special issue belongs to the Section Cellular/Molecular Immunology)

Vaccines Targeting Dendritic Cells

edited by Ronald A. Backer and Björn E. Clausen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4364 | Submission Open

Keywords: vaccines; dendritic cells; antigen targeting; immune responses; adjuvant; cancer immunotherapy; T cell activation

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

HIV Vaccine Development and Clinical Trails

edited by Massimiliano Bissa

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3551 | Submission Open

Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies

(This special issue belongs to the Section HIV Vaccines)

Promoting Research, Development and Access to Vaccines to Address Global Inequities

edited by

Yangmu Huang

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3014 | Submission Open

Keywords: research and development; communicable diseases; vulnerable population; medical countermeasures; vaccine-preventable diseases; innovative vaccines; vaccine hesitancy; health education; vaccination coverage rates; vaccination strategies

(This special issue belongs to the Section Vaccine Efficacy and Safety)

Novel Viral Vaccine and Molecular Immunology

edited by

Chang Li

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2730 | Submission Open

Keywords: viral infectious diseases; novel vaccines; immune mechanism

(This special issue belongs to the Section Cellular/Molecular Immunology)

Acceptance and Hesitancy in Vaccine Uptake: 2nd Edition

edited by Sherri Sheinfeld Gorin

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2711 | Submission Open

Keywords: vaccine acceptance; vaccine hesitancy; vaccine uptake; vaccination

(This special issue belongs to the Section Human Vaccines and Public Health)

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