Special Issues

Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recombinant Vaccine for Human and Animal Diseases
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 14719 | Submission Open
Keywords: subunit vaccines; protein expression; synthetic biology; virus like particles; bacterial antigens; baculovirus antigens; plant antigens
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines to Reduce Antimicrobial Resistance to Bacterial Pathogens
edited by , Astrid Pérez and Eva Gato
submission deadline 28 Feb 2026 | 3 articles | Viewed by 12194 | Submission Open
Keywords: antimicrobial resistance; immune responses; infectious diseases; bacterial vaccines; antibody response; cellular response; mucosal immunity; efficacy evaluation; vaccine development
(This special issue belongs to the Section Pathogens-Host Immune Boundaries)
Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition submission deadline 28 Feb 2026 | 6 articles | Viewed by 10363 | Submission Open
Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
The Effectiveness of Influenza Vaccine
edited by Filippo Ansaldi and
submission deadline 28 Feb 2026 | 3 articles | Viewed by 8323 | Submission Open
Keywords: effectiveness; influenza vaccines; infection control; influenza vaccination; seasonal influenza vaccines
(This special issue belongs to the Section Influenza Virus Vaccines)
Safety and Side Effects in SARS-CoV-2 Vaccine
edited by and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 7941 | Submission Open
Keywords: COVID-19 vaccine; vaccine adverse event reporting system (VAERS); vaccine safety datalink (VSD); adverse event; safety and side effects
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Enterovirus Vaccines Development and Immune Responses Following Immunization
edited by and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 7635 | Submission Open
Keywords: enterovirus; vaccine; immune efficacy; immune response
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design
edited by Tony W. Ng and Steven A. Porcelli
submission deadline 28 Feb 2026 | 3 articles | Viewed by 5661 | Submission Open
Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Vaccination and Infectious Disease Epidemics submission deadline 28 Feb 2026 | 3 articles | Viewed by 4096 | Submission Open
Keywords: vaccination; infectious disease; epidemics; vaccination efficacy
(This special issue belongs to the Section Vaccines against Infectious Diseases)
Nanoparticle-Based Delivery Systems for Vaccines submission deadline 28 Feb 2026 | 2 articles | Viewed by 2725 | Submission Open
Keywords: virus-like particle; nanocage; chimeric antigen; mucosal vaccine; nanoadjuvant; nanoparticle
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Receptor-Binding Domain-Based Vaccines Against SARS-CoV-2
edited by Puthupparampil Scaria
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2118 | Submission Open
Keywords: RBD vaccine; COVID-19; vaccine; SARS-CoV-2
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Advances in DNA Vaccine Research
edited by Dabbu Jaijyan
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2045 | Submission Open
Keywords: DNA vaccines; DNA-vectored vaccine; vectors for DNA vaccines; adjuvants; DNA vaccine delivery
(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)
Vaccine Strategies to Prevent Community-Acquired Pneumonia submission deadline 28 Feb 2026 | Viewed by 839 | Submission Open
Keywords: community-acquired respiratory infections; Streptococcus pneumoniae; Staphylococcus aureus; influenza; pneumonia; respiratory infections; respiratory pathogens
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Mucosal Vaccines: Advances in Technology and Delivery
edited by , Shangen Xu and Yuhong Lin
submission deadline 28 Feb 2026 | 1 articles | Viewed by 557 | Submission Open
Keywords: mucosal immunization; mucosal vaccine; adjuvant; vaccine delivery strategy; vaccine formulations; immune response
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Advancements in NK Vaccines for Solid Tumors: A Focus on Ongoing Clinical Trials
edited by
submission deadline 28 Feb 2026 | Viewed by 553 | Submission Open
Keywords: natural killer (NK) cell-based vaccines; solid tumors; cancer immunotherapy; clinical trials; immune response modulation
Recent Advances in Ruminant Vaccines
edited by
submission deadline 28 Feb 2026 | Viewed by 378 | Submission Open
Keywords: mastitis; ruminant; vaccine; mammary gland; cattle; inflammation
Memory T Cells in Vaccine-Induced Immunity for Infectious Diseases
edited by Bingdong Zhu
submission deadline 28 Feb 2026 | Viewed by 374 | Submission Open
Keywords: memory T cells; vaccination; adjuvant; immune strategy; infectious disease
Cancer Vaccines: Current Advances, Clinical Applications, and Future Directions
edited by , Kajetan Kiełbowski and
submission deadline 28 Feb 2026 | Viewed by 309 | Submission Open
Keywords: cancer; cancer vaccines; tumor microenvironment; mRNA vaccines; DNA vaccines; neoantigen vaccines; translational medicine
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
SARS-CoV-2: Infections, Treatment, and Development of Vaccines—2nd Edition submission deadline 28 Feb 2026 | Viewed by 236 | Submission Open
Keywords: SARS-CoV-2; vaccines; COVID-19; diagnosis; treatment; antibodies; monoclonal antibodies; recombinant protein
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Advances in Veterinary Vaccine Development and Immunoprophylaxis for Livestock Diseases
edited by and
submission deadline 28 Feb 2026 | Viewed by 210 | Submission Open
Keywords: livestock vaccines; veterinary immunoprophylaxis; antibody-based vaccines; nanobodies; passive immunization strategies; One Health vaccinology; sustainable animal health
(This special issue belongs to the Section Veterinary Vaccines)
Applications of Nanoparticles in Vaccines
edited by Kirsty Wilson, and Nhiem L. Tran
submission deadline 28 Feb 2026 | Viewed by 208 | Submission Open
Keywords: nanoparticles; vaccine design; nanoparticle applications in vaccines; antigen incorporation with nanoparticles; physicochemical properties of nanoparticles; adjuvant properties of nanoparticles; mechanisms of nanovaccines; immune response; disease models
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Advances in Vaccines Against Infectious Diseases submission deadline 1 Mar 2026 | 17 articles | Viewed by 51601 | Submission Open
Keywords: vaccination; antigens; disease; immune; immunity; vaccine delivery; host responses; biodefence; emerging pathogens; MERS; parasites; virus; bacteria; adjuvants
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
African Swine Fever Virus Immunotherapies and Vaccine Development
edited by and Xiaodong Qin
submission deadline 1 Mar 2026 | 1 articles | Viewed by 1588 | Submission Open
Keywords: ASFV; vaccine development; pathogenesis; immune evasion; diagnostic tools and technologies
(This special issue belongs to the Section Veterinary Vaccines)
Innovations in Vaccines for Poorly Responding Populations
edited by Martha Alexander-Miller and Kenneth E. Schmader
submission deadline 15 Mar 2026 | Viewed by 371 | Submission Open
Keywords: vaccines; infants; newborns; elderly; immunocompromised; high-risk populations; adjuvants; novel vacine platforms; correlates of protection; vaccine effectiveness
Advances in Cancer Immunotherapy and Vaccines Research: 2nd Edition
edited by
submission deadline 20 Mar 2026 | 8 articles | Viewed by 27466 | Submission Open
Keywords: tumor vaccine; immune adjuvants; tumor immune environment; peptide vaccine; chemoradiotherapy; cytokines; suppressive immune cells; checkpoint inhibitors
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Advancements in Vaccine Research: Epidemiology, Immunogenicity, Effectiveness and Safety
edited by
submission deadline 20 Mar 2026 | 6 articles | Viewed by 13131 | Submission Open
Keywords: vaccine epidemiology; immune response; immunogenicity; vaccine effectiveness; safety; infectious diseases; public health; vaccine development; immunization strategies
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Innovative Strategies to Boost the Immunogenicity of Cancer Vaccines
edited by Eric O'Neill and
submission deadline 20 Mar 2026 | Viewed by 304 | Submission Open
Keywords: cancer vaccines; tumor antigens; tumor-associated antigens (TAAs); tumor-specific antigens (TSAs); subunit vaccines; peptide vaccines; mRNA vaccines; viral vector vaccines; adjuvants; antigen presentation; MHC class I and II upregulation; cancer immunotherapy; antibody– drug conjugates (ADCs); T cell engages; combination immunotherapy
Porcine Bacteria and Virus Vaccines
edited by Huixing Lin
submission deadline 25 Mar 2026 | Viewed by 363 | Submission Open
Keywords: Porcine; bacteria; virus; vaccine; diarrhea; dyspnea; adjuvant; attenuated vaccine; live vector vaccine; peptide vaccine
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines and Vaccine Preventable Diseases
edited by Elie Saade and Stefan Gravenstein
submission deadline 31 Mar 2026 | 8 articles | Viewed by 32076 | Submission Open
Keywords: vaccine-preventable diseases (VPDs); at-risk populations; older adults; nosocomial transmission; vaccine equity; immunization disparities; public health policy; social determinants of health; infection control; prophylactic and therapeutic vaccines
(This special issue belongs to the Section Vaccines and Public Health)
The Recent Development of Influenza Vaccine: 2nd Edition submission deadline 31 Mar 2026 | 8 articles | Viewed by 21340 | Submission Open
Keywords: influenza; older population; adjuvants; universal vaccine
(This special issue belongs to the Section Influenza Virus Vaccines)
Evaluating the Immune Response to RNA Vaccine
edited by and Huajun Zhao
submission deadline 31 Mar 2026 | 5 articles | Viewed by 17475 | Submission Open
Keywords: RNA vaccine; mechanism of action; immune regulation; innate immunity; adaptive vaccine response
(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)
Viral Vector-Based Vaccines and Therapeutics
edited by Sujit Pujhari
submission deadline 31 Mar 2026 | 7 articles | Viewed by 14292 | Submission Open
Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Animal Diseases: Immune Response and Vaccines
edited by , José M. Rojas and
submission deadline 31 Mar 2026 | 8 articles | Viewed by 12270 | Submission Open
Keywords: immune responses; ruminants; vaccines; animal health
(This special issue belongs to the Section Veterinary Vaccines)
The Role of Vaccination on Public Health and Epidemiology
edited by and Daniela Reis Joaquim de Freitas
submission deadline 31 Mar 2026 | 4 articles | Viewed by 12024 | Submission Open
Keywords: vaccines; immunization; epidemiology; public health; vaccine-preventable diseases; pandemic preparedness; health equity
(This special issue belongs to the Section Vaccines and Public Health)
Herpes Simplex Virus Infection, Immunity, and Vaccine Development
edited by and Swayam Prakash
submission deadline 31 Mar 2026 | 1 articles | Viewed by 8369 | Submission Open
Keywords: Herpes Simplex Virus (HSV); protection; humoral; and cellular immune mechanisms; vaccine development; HSV-1; HSV-2; immunization strategies
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Cancer Vaccines: 4th Edition
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 7294 | Submission Open
Keywords: cancer immunotherapy; therapeutic vaccine; tumor-associated antigens; neoantigens; adjuvant; tumor microenvironment; oncolytic viruses; immune checkpoint inhibitors
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Hepatitis Vaccines: Safety, Efficacy and Global Impact submission deadline 31 Mar 2026 | 3 articles | Viewed by 6977 | Submission Open
Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges
(This special issue belongs to the Section Hepatitis Virus Vaccines)
From Knowledge to Action: Advances in Herpes Zoster Vaccine and Vaccination
edited by Giulia Silvestrini and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 6394 | Submission Open
Keywords: knowledge; attitudes; and practices regarding herpes zoster vaccination; vaccine hesitancy; vaccine uptake and inequality; efficacy; reactogenicity; and safety of herpes zoster vaccine; efficacy of different vaccines; the role of different type of herpes zoster vaccine in different target of population; active campaign
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Novel Adjuvants and Delivery Systems for Vaccines
edited by Christiane Chbib and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4479 | Submission Open
Keywords: vaccines; drug development; adjuvants; nanoparticle
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Factors Affecting Influenza Vaccine Uptake
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2585 | Submission Open
Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups
(This special issue belongs to the Section Influenza Virus Vaccines)
Vaccination Strategies and Population Immunity
edited by Matthew S. McGlone and Mian Jia
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1847 | Submission Open
Keywords: vaccination strategies; population immunity; health equity; vaccine access
(This special issue belongs to the Section Vaccines and Public Health)
Vaccines and Immunotherapy for Inflammatory Disease
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1743 | Submission Open
Keywords: vaccines; immunotherapy; inflammation; autoimmune disease; cytokines; immune modulation; chronic inflammatory diseases; immune response; vaccine development; translational immunology
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Influenza Virus Infections, Vaccines and Diagnosis
edited by , Isabel Pagani and Valeria Caputo
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1657 | Submission Open
Keywords: influenza; avian influenza; monoclonal antibodies; vaccine; therapy; infection
(This special issue belongs to the Section Influenza Virus Vaccines)
Epidemiology, Immunology, and Therapeutic Vaccines of Enteric Pathogens submission deadline 31 Mar 2026 | 1 articles | Viewed by 1497 | Submission Open
Keywords: enteric infectious diseases; vaccine development; intestinal immune response; mucosal immunology; therapeutic immunization strategies; epidemiology
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Cancer Vaccines and Immunotherapies submission deadline 31 Mar 2026 | Viewed by 512 | Submission Open
Keywords: cancer vaccines; tumor immunology; immunotherapy; mRNA vaccines; neoantigen-based therapies
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Vaccine Development for Influenza Virus: 2nd Edition submission deadline 31 Mar 2026 | 1 articles | Viewed by 473 | Submission Open
Keywords: influenza vaccine; adjuvant; mRNA vaccine; novel vaccine technology; nanotechnology; immune response; animal; human
(This special issue belongs to the Section Influenza Virus Vaccines)
HPV Vaccines and New Vaccination Schedules Implementation
edited by , Aurelio Cruz-Valdez and Vicente Madrid-Marina
submission deadline 31 Mar 2026 | Viewed by 366 | Submission Open
Keywords: papillomavirus vaccines; vaccination schedule; HPV vaccine efficacy; vaccine uptake; implementation
(This special issue belongs to the Section Human Papillomavirus Vaccines)
SARS-CoV-2 Infection and COVID-19 Vaccination: Exploring Pathogenesis, Immune Response and Immunopathogenic Complications
edited by , Tamara Rodrigues and Flavio Protasio Veras
submission deadline 31 Mar 2026 | Viewed by 359 | Submission Open
Keywords: SARS-CoV-2; COVID-19; vaccine adverse events; myocarditis and thrombosis; multisystem inflammatory syndrome; long COVID-19; immune response and autoimmunity; post-vaccine complications; therapeutic strategies; vaccine safety
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Advancing Vaccine Strategies Against Viral Hemorrhagic Fevers: Innovation and Challenges submission deadline 31 Mar 2026 | Viewed by 346 | Submission Open
Keywords: viral hemorrhagic fevers; vaccines; Flaviviridae; Arenaviridae; Bunyaviridae; Filoviridae; Nairoviridae; Paramyxoviridae; Phenuiviridae
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Bio-Inspired Nanocarriers in Next-Generation Vaccines Against Bacterial and Viral Pathogens submission deadline 31 Mar 2026 | Viewed by 341 | Submission Open
Keywords: lipid nanoparticles; liposomes; extracellular vesicles; nanovesicles; nanomedicine
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Developing Recombinant Vaccines and Immunotherapy Strategies for Emerging Viral Diseases submission deadline 31 Mar 2026 | Viewed by 331 | Submission Open
Keywords: emerging viral diseases; recombinant vaccines; immunotherapy; vaccine development; immune modulation
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
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