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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Virus-Like Particle-Based Vaccines

edited by

Abel Gutiérrez-Ortega

submission deadline 31 Dec 2025 | Viewed by 241 | Submission Open

Keywords: virus-like particles (VLPs); vaccine design; immune response mechanisms; clinical trials; therapeutic vaccines; vaccine manufacturing; antigen delivery; rapid vaccine development

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immune-Mediated Diseases Following Vaccination

edited by

Giampiero Girolomoni

submission deadline 31 Dec 2025 | Viewed by 232 | Submission Open

Keywords: immune-mediated diseases; autoimmune diseases; atopic dermatitis; asthma; rheumatic diseases; vasculitis

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Development of Broadly Protective Vaccines Against Respiratory Virus Infections

edited by

Noopur Bhatnagar

and Jerry W. Simecka

submission deadline 20 Jan 2026 | Viewed by 379 | Submission Open

Keywords: broadly protective vaccines; respiratory viruses; universal vaccines; cross-protective immunity; vaccine development; mucosal immunity; T-cell responses; broadly neutralizing antibodies; immunogenicity; vaccine efficacy

Maternal Vaccination and Vaccines

edited by

Gianluca Straface

submission deadline 31 Jan 2026 | 6 articles | Viewed by 30990 | Submission Open

Keywords: prenatal care; vaccination; vaccination hesitancy; Tdap vaccine; influenza vaccine; COVID-19 vaccine

(This special issue belongs to the Section Vaccines and Public Health)

Prevention of Human Papillomavirus and Vaccines Strategies

edited by

Rui Gil da Costa

submission deadline 31 Jan 2026 | 5 articles | Viewed by 24346 | Submission Open

Keywords: human papillomavirus; HPV vaccines; vaccination strategies; cervical cancer prevention; therapeutic vaccines

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccines and Vaccination: HIV, Hepatitis Viruses, and HPV

edited by

Ivan Schietroma

and

Sonia Moretti

submission deadline 31 Jan 2026 | 8 articles | Viewed by 24174 | Submission Open

Keywords: preventative vaccine; therapeutic vaccine; HIV; hepatitis A; hepatitis B; human papillomavirus; sexually transmitted infections; immunoprotection; vaccination; preventable diseases

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Fish Disease Occurrence and Immune Prevention and Control

edited by

Yonghua Hu

Jianmin Ye

and Yang Zhou

submission deadline 31 Jan 2026 | 4 articles | Viewed by 19027 | Submission Open

Keywords: fish immunology; fish disease; pathogenesis; virulence factor; disease prevention and control; vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Virus-Like Particle Vaccine Development

edited by

Jian Xu

submission deadline 31 Jan 2026 | 7 articles | Viewed by 18342 | Submission Open

Keywords: vaccine; virus-like particle; display; protein production; immunogenicity

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunity to Influenza Viruses and Vaccines

edited by

Rongbao Gao

submission deadline 31 Jan 2026 | 7 articles | Viewed by 15789 | Submission Open

Keywords: avian influenza; etiology; antiviral immunity; serology; vaccine; pathogenesis

(This special issue belongs to the Section Influenza Virus Vaccines)

Innovations in Vaccine Technology

edited by

Rachel Stephenson

submission deadline 31 Jan 2026 | 8 articles | Viewed by 15719 | Submission Open

Keywords: inactivated vaccines; live-attenuated vaccines; messenger RNA (mRNA) vaccines; subunit; recombinant; polysaccharide and conjugate vaccines; toxoid vaccines; viral vector vaccines; personalized vaccines; antigen design; reverse vaccinology; lipid nanoparticles; cell-based vaccine production; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Next-Generation Vaccine and Immunotherapy

edited by

Takashi Imai

submission deadline 31 Jan 2026 | 4 articles | Viewed by 14324 | Submission Open

Keywords: next-generation vaccine; immunotherapy; pathogens; cancers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Analysis of Vaccine-Induced Adaptive Immune Responses

edited by

Francesco Nicoli

and

Antonella Caputo

submission deadline 31 Jan 2026 | 5 articles | Viewed by 14324 | Submission Open

Keywords: RNA sequencing; flow cytometry; microscopy; T cells; B cells; antibodies; biochemistry; molecular biology; systems biology; epitope prediction

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Recent Scientific Development of Poliovirus Vaccines

edited by

Lester M. Shulman

submission deadline 31 Jan 2026 | 6 articles | Viewed by 11939 | Submission Open

Keywords: novel oral polio vaccines (nOPV); vaccine-derived poliovirus (VDPV); recombination; inactivated oral vaccine strains (sIPV); edible vaccines; non-infectious vaccine-like particles (VLPs); subdermal administration of fractional doses; adjuvants; edible vaccines; microarray patches

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Development and Global Health

edited by

Anna Paczkowska

Karolina Hoffmann

and

Krzysztof Kus

submission deadline 31 Jan 2026 | 3 articles | Viewed by 11251 | Submission Open

Keywords: next-generation vaccines; clinical efficacy of vaccines; vaccine safety; treatment methods for civilization diseases; public health; prevention of civilization diseases

(This special issue belongs to the Section Vaccines and Public Health)

Advances in Vaccine Adjuvants

edited by Devyani Joshi and Sanjeev Kumar

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6267 | Submission Open

Keywords: infectious diseases; cancer vaccines; mechanisms of adjuvants; novel adjuvants; delivery systems; particulate adjuvants; innate immune response; adaptive immune response

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Respiratory Viruses and Antiviral Immunity

edited by

Andreu Comas-Garcia

Sofía Bernal-Silva

and

Maria Grazia Cusi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 6195 | Submission Open

Keywords: respiratory viruses; innate antiviral response; adaptative antiviral response; prevention; damage; viral clearance

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Effectiveness and Safety of Vaccines in Special Populations

edited by Arjan Harxhi and

Justyna Dominika Kowalska

submission deadline 31 Jan 2026 | 4 articles | Viewed by 5655 | Submission Open

Keywords: vaccines; special populations; HIV; pregnancy; migrants

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Immune Responses in Patients with Inflammatory Bowel Disease After Vaccination

edited by

Phil-Robin Tepasse

and Arne Bokemeyer

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4914 | Submission Open

Keywords: inflammatory bowel disease; vaccination; opportunistic infections; immune response; immunomodulatory therapy

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Host Immunity and Vaccines for Respiratory Pathogens

edited by

Hanqing He

and

Yuxia Liang

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4360 | Submission Open

Keywords: vaccines; immunity; infectious disease; respiratory pathogens

Development of Novel Mucosal Vaccines: Advances in Technology and Delivery

edited by

Mohamed I. Husseiny El-Sayed

submission deadline 31 Jan 2026 | 1 articles | Viewed by 4239 | Submission Open

Keywords: oral vaccines; nasal vaccines; live attenuated vaccines; DNA vaccines; mRNA vaccines; viral vectors vaccine; nanoparticle delivery system; adjuvants; gene-based vaccine; microencapsulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Challenges to Developing New Vaccines and Improving Existing Platforms

edited by

S. Louise Cosby

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4141 | Submission Open

Keywords: infectious disease; cancer vaccines; humoral and cellular immunity; flaviviruses vaccines; inactivated and subunit vaccines; novel assays

Vaccine Design and Development

edited by

Vladimir Temchura

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3758 | Submission Open

Keywords: vaccine design; vaccine development; vaccinology; immunization; immune response; vaccine delivery; vaccine efficacy

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Pandemic Influenza Vaccination

edited by Francisco Nogareda and Shoshanna Goldin

submission deadline 31 Jan 2026 | 5 articles | Viewed by 3415 | Submission Open

Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response

(This special issue belongs to the Section Influenza Virus Vaccines)

Novel Immunotherapies, Cell Therapies and Cancer Vaccines

edited by

Vita Golubovskaya

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3186 | Submission Open

Keywords: cell therapy; vaccine; cancer; immunotherapy; antibody

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccination Against Major Respiratory Pathogens in Livestock Farming

edited by

Enrico Brugnera

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2800 | Submission Open

Keywords: respiratory tract infections; innate and adaptive immune responses; vaccines; safety issues; risks and benefits studies

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines for Porcine Diseases

edited by Xiaohu Wang and

Lizette M. Cortes

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2185 | Submission Open

Keywords: vaccine development; immune mechanisms; adjuvants; global animal health; porcine diseases; vaccine candidate targets

(This special issue belongs to the Section Veterinary Vaccines)

Recent Research on Human Papillomavirus (HPV) Infection and Vaccination: 2nd Edition

edited by

Li Shi

and Yufeng Yao

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1744 | Submission Open

Keywords: HPV infection; HPV vaccination; willingness; hesitancy; therapeutic vaccines; cervical cancer prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Chronic Viral Infections and Cancer: Openings for Vaccines and Cure

edited by

Maria G. Isaguliants

and Karl Ljungberg

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1477 | Submission Open

Keywords: chronic viral infection; oncogenic viruses; hepatitis B virus; high risk human papillomaviruses; hepatitis C virus; epstein– barr virus; human immunodeficiency virus type I; cancer associated with viral infection; immunotherapy; prophylactic viral vaccines; therapeutic viral vaccines

Immune Responses After Malaria Infection and Next Generation Malaria Vaccine

edited by Yu-Min Chuang

submission deadline 31 Jan 2026 | Viewed by 490 | Submission Open

Keywords: humoral immune response; cellular immune response; malaria; antimalaria vaccine; Plasmodium

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Reactive Vaccination During Outbreaks

edited by Giuseppe Ippolito, Gary Kobinger and Giovanni Rezza

submission deadline 31 Jan 2026 | Viewed by 358 | Submission Open

Keywords: vaccination strategies; reactive vaccination; vaccine efficacy; efficiency; duration of protection; and the selection of populations

(This special issue belongs to the Section Vaccines and Public Health)

The Era of Vaccines: Advancing Tumor Immunology and Immunotherapy

edited by

Surendra Shukla

and

Vinay Kumar

submission deadline 31 Jan 2026 | Viewed by 239 | Submission Open

Keywords: cancer immunotherapy; tumor microenvironment; immune editing; immune checkpoints; CAR-T and NK therapy; biomarkers for immunotherapy

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Communicable Diseases: New and Old Therapies and Preventive Strategies, 2nd Edition

edited by

Cristina Genovese

Calimeri Sebastiano

, Daniela Lo Giudice,

Vincenza La Fauci

and

Vincenza Gianfredi

submission deadline 26 Feb 2026 | 1 articles | Viewed by 3213 | Submission Open

Keywords: vaccines; therapies; communicable diseases

Improving HPV Vaccination Coverage: Current Issues, Future Prospects and Strategies

edited by

Irena Ilic

submission deadline 28 Feb 2026 | 8 articles | Viewed by 18722 | Submission Open

Keywords: HPV vaccine; HPV-related cancers; vaccination; vaccine coverage; vaccine acceptance; vaccine hesitancy; vaccines knowledge; attitudes and practice; immunity; prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Viral Infections, Host Immunity and Vaccines

edited by Salman L. Butt and

Henry Kariithi

submission deadline 28 Feb 2026 | 6 articles | Viewed by 13715 | Submission Open

Keywords: multi-omics; innate immunity; spatial; virulence; persistence

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Recombinant Vaccine for Human and Animal Diseases

edited by

Shawn Babiuk

submission deadline 28 Feb 2026 | 3 articles | Viewed by 13107 | Submission Open

Keywords: subunit vaccines; protein expression; synthetic biology; virus like particles; bacterial antigens; baculovirus antigens; plant antigens

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines to Reduce Antimicrobial Resistance to Bacterial Pathogens

edited by

Miriam Moscoso

, Astrid Pérez and Eva Gato

submission deadline 28 Feb 2026 | 3 articles | Viewed by 10268 | Submission Open

Keywords: antimicrobial resistance; immune responses; infectious diseases; bacterial vaccines; antibody response; cellular response; mucosal immunity; efficacy evaluation; vaccine development

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition

edited by

Arturo Reyes-Sandoval

and

Young Chan Kim

submission deadline 28 Feb 2026 | 6 articles | Viewed by 8724 | Submission Open

Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Safety and Side Effects in SARS-CoV-2 Vaccine

edited by

Ying-Fei Yang

and

Sher Singh

submission deadline 28 Feb 2026 | 2 articles | Viewed by 6979 | Submission Open

Keywords: COVID-19 vaccine; vaccine adverse event reporting system (VAERS); vaccine safety datalink (VSD); adverse event; safety and side effects

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Enterovirus Vaccines Development and Immune Responses Following Immunization

edited by

Yuefei Jin

and

Shuaiyin Chen

submission deadline 28 Feb 2026 | 1 articles | Viewed by 6848 | Submission Open

Keywords: enterovirus; vaccine; immune efficacy; immune response

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

The Effectiveness of Influenza Vaccine

edited by Filippo Ansaldi and

Amicizia Daniela

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6034 | Submission Open

Keywords: effectiveness; influenza vaccines; infection control; influenza vaccination; seasonal influenza vaccines

(This special issue belongs to the Section Influenza Virus Vaccines)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4851 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccination and Infectious Disease Epidemics

edited by

King-Pui Florence Chan

and

Ken Ka Pang Chan

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3221 | Submission Open

Keywords: vaccination; infectious disease; epidemics; vaccination efficacy

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Nanoparticle-Based Delivery Systems for Vaccines

edited by

Sergio Rosales-Mendoza

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2237 | Submission Open

Keywords: virus-like particle; nanocage; chimeric antigen; mucosal vaccine; nanoadjuvant; nanoparticle

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Receptor-Binding Domain-Based Vaccines Against SARS-CoV-2

edited by Puthupparampil Scaria

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1928 | Submission Open

Keywords: RBD vaccine; COVID-19; vaccine; SARS-CoV-2

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advances in DNA Vaccine Research

edited by Dabbu Jaijyan

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1693 | Submission Open

Keywords: DNA vaccines; DNA-vectored vaccine; vectors for DNA vaccines; adjuvants; DNA vaccine delivery

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Vaccine Strategies to Prevent Community-Acquired Pneumonia

edited by

Vissaria Sakka

and

Garyphallia Poulakou

submission deadline 28 Feb 2026 | Viewed by 799 | Submission Open

Keywords: community-acquired respiratory infections; Streptococcus pneumoniae; Staphylococcus aureus; influenza; pneumonia; respiratory infections; respiratory pathogens

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Advancements in NK Vaccines for Solid Tumors: A Focus on Ongoing Clinical Trials

edited by

Yutao Wang

submission deadline 28 Feb 2026 | Viewed by 537 | Submission Open

Keywords: natural killer (NK) cell-based vaccines; solid tumors; cancer immunotherapy; clinical trials; immune response modulation

Mucosal Vaccines: Advances in Technology and Delivery

edited by

Kai Zhao

, Shangen Xu and Yuhong Lin

submission deadline 28 Feb 2026 | Viewed by 510 | Submission Open

Keywords: mucosal immunization; mucosal vaccine; adjuvant; vaccine delivery strategy; vaccine formulations; immune response

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Recent Advances in Ruminant Vaccines

edited by

Petr Slama

submission deadline 28 Feb 2026 | Viewed by 344 | Submission Open

Keywords: mastitis; ruminant; vaccine; mammary gland; cattle; inflammation

Memory T Cells in Vaccine-Induced Immunity for Infectious Diseases

edited by Bingdong Zhu

submission deadline 28 Feb 2026 | Viewed by 335 | Submission Open

Keywords: memory T cells; vaccination; adjuvant; immune strategy; infectious disease

Displaying special issue 51-100 on page 2 of 6.

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