Special Issues

Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Humoral and Cellular Response After Vaccination
edited by Adrian Onu and Iuliana Caras
submission deadline 31 Oct 2025 | 2 articles | Viewed by 5112 | Submission Open
Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
New Approaches to Vaccine Development and Delivery submission deadline 31 Oct 2025 | 4 articles | Viewed by 4943 | Submission Open
Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
HIV Vaccine Development and Clinical Trails
edited by Massimiliano Bissa
submission deadline 31 Oct 2025 | 2 articles | Viewed by 4636 | Submission Open
Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies
(This special issue belongs to the Section HIV Vaccines)
Vaccine Efficacy and Safety in Transplant Recipients
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3597 | Submission Open
Keywords: transplant recipients; vaccination; kidney; heart; lung; stem cell transplants; safety; antibody response; efficacy
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Novel Viral Vaccine and Molecular Immunology
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3360 | Submission Open
Keywords: viral infectious diseases; novel vaccines; immune mechanism
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Personalised Cancer Vaccines
edited by Andrew L. Coveler
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3099 | Submission Open
Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Advances in Allergy, Clinical Immunology, and Vaccines
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2668 | Submission Open
Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Infectious Diseases and Immunization in Animals
edited by , Ezgi Akdesir and
submission deadline 31 Oct 2025 | 3 articles | Viewed by 1897 | Submission Open
Keywords: animal vaccination; zoonotic diseases; One Health; host– pathogen interaction; veterinary immunology; emerging infectious diseases; antimicrobial resistance; vaccine development
(This special issue belongs to the Section Veterinary Vaccines)
Research in Vaccine Adjuvants: Innovations and Challenges
edited by Haibo Li and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1524 | Submission Open
Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Innovations Advancing Vaccine Preparedness and Response Capabilities to Counter Pandemic Influenza
edited by , Sam Lee, and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1061 | Submission Open
Keywords: influenza vaccines; efficacy; vaccine uptake; rapid manufacturing; vaccine mechanism of action; alternative routes of administration; single-dose regimens
(This special issue belongs to the Section Influenza Virus Vaccines)
Antiviral Immunity and Vaccine Development
edited by and Tao Yu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 862 | Submission Open
Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics
(This special issue belongs to the Section Pathogens-Host Immune Boundaries)
The Development of Recombinant and Subunit Vaccines Against Infectious Diseases
edited by
submission deadline 31 Oct 2025 | Viewed by 573 | Submission Open
Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants
(This special issue belongs to the Section Vaccines against Infectious Diseases)
Pandemic Influenza Vaccination
edited by Francisco Nogareda and Shoshanna Goldin
submission deadline 31 Oct 2025 | Viewed by 544 | Submission Open
Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response
(This special issue belongs to the Section Influenza Virus Vaccines)
The Development of Peptide-Based Vaccines submission deadline 31 Oct 2025 | Viewed by 311 | Submission Open
Keywords: peptide antigens; vaccine design; immunogenicity; epitope mapping; adjuvants; multi-epitope vaccines; personalized peptide vaccines; vaccine delivery systems; computational vaccine design; synthetic peptides
Nanomaterial Application in Vaccines
edited by and
submission deadline 31 Oct 2025 | Viewed by 95 | Submission Open
Keywords: nanomaterials; vaccine delivery; immunogenicity enhancement; tolerogenic nanovaccine; nanotechnology; vaccine stability; vaccine design; nanoparticles; immunization strategies; biotechnology in vaccines
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Bioengineering in Vaccine Design and Delivery
edited by
submission deadline 1 Nov 2025 | 3 articles | Viewed by 8167 | Submission Open
Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design
edited by Tony W. Ng and Steven A. Porcelli
submission deadline 1 Nov 2025 | 2 articles | Viewed by 3650 | Submission Open
Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Molecular Virology and Translational Research in Antiviral Vaccine Development
edited by
submission deadline 20 Nov 2025 | Viewed by 213 | Submission Open
Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses
COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition
edited by and
submission deadline 30 Nov 2025 | 21 articles | Viewed by 99730 | Submission Open
Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Feature Papers of DNA and mRNA Vaccines
edited by
submission deadline 30 Nov 2025 | 10 articles | Viewed by 45237 | Submission Open
(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)
Advance Public Health Through Vaccination
edited by , Maria Rosaria Gualano, and
submission deadline 30 Nov 2025 | 15 articles | Viewed by 31748 | Submission Open
Keywords: epidemiology; vaccination  strategies; vaccine hesitancy; health equity; vulnerable population
(This special issue belongs to the Section Vaccines and Public Health)
Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects
edited by and Afsheen Raza
submission deadline 30 Nov 2025 | 4 articles | Viewed by 9871 | Submission Open
Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases
edited by and
submission deadline 30 Nov 2025 | 5 articles | Viewed by 8869 | Submission Open
Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Advanced Concepts in Vaccines in Public Health
edited by and Maria Elena Flacco
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7653 | Submission Open
Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness
(This special issue belongs to the Section Vaccines and Public Health)
Advances in HIV Vaccine Development, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 4178 | Submission Open
Keywords: HIV; envelope glycoprotein; vaccine; adjuvant; antibody; neutralization; ADCC; ADCP; complement; cellular immune response
(This special issue belongs to the Section HIV Vaccines)
Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition
edited by Juan Yang and Wei Wang
submission deadline 30 Nov 2025 | 3 articles | Viewed by 3603 | Submission Open
Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
The Vaccine Development and Study of Swine Diseases
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2434 | Submission Open
Keywords: swine diseases; viruses; vaccines; protection; control
(This special issue belongs to the Section Veterinary Vaccines)
Intracellular Parasites: Immunology, Resistance, and Therapeutics
edited by and Nagendran Tharmalingam
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2149 | Submission Open
Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles
(This special issue belongs to the Section Pathogens-Host Immune Boundaries)
New Insights into Vaccination and Public Health: 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1729 | Submission Open
Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases
(This special issue belongs to the Section Vaccines and Public Health)
Animal Infectious Diseases and Vaccinology in One Health
edited by and Elizabeth Loza-Rubio
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1085 | Submission Open
Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses
(This special issue belongs to the Section Veterinary Vaccines)
Bacterial and Viral Infections: Current Challenges and Vaccine Innovations
edited by Dima El Safadi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 909 | Submission Open
Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health
(This special issue belongs to the Section Pathogens-Host Immune Boundaries)
Cost-Effectiveness of Vaccines and Public Health
edited by Sachin A. Silva
submission deadline 30 Nov 2025 | Viewed by 715 | Submission Open
Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs
(This special issue belongs to the Section Vaccines and Public Health)
Vaccines Design Against Porcine Circovirus submission deadline 30 Nov 2025 | Viewed by 551 | Submission Open
Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method
(This special issue belongs to the Section Veterinary Vaccines)
Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination submission deadline 30 Nov 2025 | Viewed by 375 | Submission Open
Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination
(This special issue belongs to the Section Vaccines and Public Health)
Tuberculosis Diagnosis and Vaccines Research
edited by Shumaila Nida Javed Tunio
submission deadline 30 Nov 2025 | Viewed by 274 | Submission Open
Keywords: developing new diagnostic methods; new drugs; new vaccines for tuberculosis
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 122 | Submission Open
Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Vaccines for Porcine Coronaviruses
edited by
submission deadline 1 Dec 2025 | Viewed by 339 | Submission Open
Keywords: porcine coronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); porcine deltacoronavirus (PDCoV); swine acute diarrhea syndrome coronavirus (SADS-CoV); porcine respiratory coronavirus (PRCV); porcine hemagglutinating encephalomyelitis virus (PHEV); vaccine; immune response; protective efficacy
(This special issue belongs to the Section Veterinary Vaccines)
Vaccination and Public Health in the 21st Century submission deadline 20 Dec 2025 | 9 articles | Viewed by 10403 | Submission Open
Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development
(This special issue belongs to the Section Vaccines and Public Health)
Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases
edited by Wandi Zhu
submission deadline 20 Dec 2025 | Viewed by 240 | Submission Open
Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity
Human Immune Responses to Infection and Vaccination submission deadline 31 Dec 2025 | 8 articles | Viewed by 12886 | Submission Open
Keywords: vaccine immunogenicity; adjuvants; new generation of vaccines; vaccine development; immune regulation; translational vaccinology; system vaccinology; herd immunity; vaccine safety; correlates of protection
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 10558 | Submission Open
Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Health Technology Assessment of Vaccination: Strategies, Public Health and Values
edited by Maarten J. Postma, Jurjen Van der Schans and
submission deadline 31 Dec 2025 | 5 articles | Viewed by 8303 | Submission Open
Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy
(This special issue belongs to the Section Vaccines and Public Health)
Vaccines Against Poultry Viruses
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 7403 | Submission Open
Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs
(This special issue belongs to the Section Veterinary Vaccines)
Recent Scientific Advances in Vaccines for Shigella
edited by Akamol Suvarnapunya, Kristen A Clarkson, Renee Laird and August Louis Bourgeois
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4738 | Submission Open
Keywords: Shigella; vaccines; global health
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Prevention of Human Papillomavirus (HPV) and Vaccination submission deadline 31 Dec 2025 | 3 articles | Viewed by 4718 | Submission Open
Keywords: HPV vaccination; screening; PAP test; HPV-DNA test; HPV vaccine coverage; vaccine hesitancy; promotion
(This special issue belongs to the Section Human Papillomavirus Vaccines)
Strategies for the Monitoring, Treatment, and Prevention of Mpox and Other Poxvirus Infections
edited by Patrick Obermeier and Susanne Buder
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4486 | Submission Open
Keywords: poxvirus; mpox; emerging infection; epidemiology; surveillance; vaccine; vaccine efficacy; immunity; one health; global health
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
The Development of mRNA Vaccines
edited by Minghui Yang, Yuming Li and Bo Hu
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4438 | Submission Open
Keywords: nanoparticle delivery system; mRNA vaccines; infectious disease; tumor immunity; adjuvant
(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)
Vaccines for the Vulnerable Population
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 4372 | Submission Open
Keywords: vaccines; vulnerable populations; infectious diseases; immunization
(This special issue belongs to the Section Vaccines and Public Health)
Vaccines and Antibody-Based Therapeutics Against Infectious Disease
edited by Suman Kundu
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3446 | Submission Open
Keywords: infectious disease; vaccine; antibody; therapy; agriculture; protection
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Strategies to Enhance Vaccine Uptake and Immunization Among Underserved Populations/Vulnerable Groups submission deadline 31 Dec 2025 | 2 articles | Viewed by 3288 | Submission Open
Keywords: vaccine uptake; vulnerable populations; health interventions; vaccine hesitancy; public health strategies; health education and equity
(This special issue belongs to the Section Vaccines and Public Health)
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