Advances in DNA Vaccine Research
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Nucleic Acid (DNA and mRNA) Vaccines".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 726
Special Issue Editor
Special Issue Information
Dear Colleagues,
Vaccines contain specific antigens, which are inactivated or weakened pathogens that trigger the immune system in vaccinated individuals. Vaccinating people can help prevent the spread of diseases and reduce the impact of pathogens. Recently, DNA vaccines have emerged as a promising method for preventing and controlling diseases. They consist of a plasmid with a DNA sequence encoding a target protein or antigen that activates the host's immune response. DNA vaccines offer many advantages, including increased stability, easy scalability and production, lack of any infectious agents, safe storage and easy handling, while also inducing both cellular and cell-mediated immunity. Additionally, the efficacy of DNA vaccines can be further enhanced by vehicles that help the contents of DNA vaccines enter specific cells. However, further research is needed to fully understand the immune response induced by DNA vaccines and its mechanisms. In this Special Issue, we welcome original research articles and reviews in the following areas:
- DNA vaccines;
- Methods for DNA vaccine production;
- Methods for DNA vaccine delivery, including liposomes, nanoparticles, viral vector-based delivery and other platforms;
- Vector design for DNA vaccines;
- Vaccine insert design;
- Adjuvants for DNA vaccines;
- DNA vaccine delivery;
- Immune response induced by DNA vaccines;
- Applications of DNA vaccines;
- Plasmid-based vaccines;
- Advantages of DNA vaccines;
- DNA vaccine formulations.
Dr. Dabbu Jaijyan
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA vaccines
- DNA-vectored vaccine
- vectors for DNA vaccines
- adjuvants
- DNA vaccine delivery
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