The Development of HIV Vaccines: Advances and Challenges

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "HIV Vaccines".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 42

Special Issue Editor


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Guest Editor
Department of Microbiology, Immunology & Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA
Interests: HIV accessory genes; HIV-related lipid dysregulation; HIV-related mechanisms of inflammation; HIV-infected cells; anti-HIV compounds; HIV-1 translocation
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Special Issue Information

Dear Colleagues,

This Special Issue aims to showcase research and emerging challenges in developing HIV vaccines. We invite original research articles, reviews, and perspectives that explore novel immunogens, innovative adjuvants, and advancements in vaccine delivery platforms. Submissions that focus on immune correlates of protection, strategies to elicit broadly neutralizing antibodies, and lessons learned from past vaccine trials are highly encouraged. We are particularly interested in studies that address advanced immunological concepts, including trained immunity, epigenetic reprogramming of innate responses, and the role of heterologous immunity in vaccine efficacy. Manuscripts discussing novel vaccine strategies, such as mRNA platforms, are encouraged, as are contributions that examine immune-metabolic regulation in vaccine-induced responses.

I look forward to receiving your contributions.

Prof. Dr. Michael Bukrinsky
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HIV vaccine
  • trained immunity
  • broadly neutralizing antibodies
  • T-cell immunity
  • epigenetic reprogramming
  • immune metabolism
  • systems immunology
  • adjuvants
  • mucosal immunity

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Published Papers

This special issue is now open for submission.
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