Vaccination Against Vector-Borne Diseases: Bridging Public Health and Epidemiology

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines against Tropical and other Infectious Diseases".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 698

Special Issue Editors


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Guest Editor
DIM Section of Occupational Medicine "EC Vigliani", Università degli studi di Bari Aldo Moro, 70121 Bari, Italy
Interests: immunology; occupational autoimmune diseases; zoonotic viruses seroprevalence in occupational setting
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Molecular and Developmental Medicine, University of Siena, Banchi di Sotto, 55, 53100 Siena, Italy
Interests: influenza vaccines; correlates of protection; vaccine-preventable diseases; seroepidemiology; SARS-CoV-2
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to explore the pivotal role that vaccination plays in preventing vector-borne diseases, focusing on how vaccination strategies intersect with public health and epidemiology to address these global health threats. Vector-borne diseases—such as malaria, dengue, Zika, and chikungunya—are transmitted by insects like mosquitoes and ticks, posing unique challenges due to environmental, ecological, and socioeconomic factors that influence disease spread and vaccine efficacy.

This Special Issue aims to focus on the recent advancements in vaccine development, including novel vaccine candidates and technologies targeting vector-borne pathogens. Emphasis is placed on how epidemiological data can inform vaccine deployment, maximizing the impact of immunization programs within vulnerable communities and high-risk regions. Articles within this Special Issue should also examine public health frameworks, discussing how surveillance systems, community engagement, and health education can be strengthened to support vaccination efforts. This Special Issue also aims to address factors which influence vector-borne diseases that require adaptive vaccination strategies. Overall, this Special Issue aims to showcase how vaccines, when integrated with robust public health and epidemiological frameworks, offer a powerful tool to reduce the burden of diseases worldwide. 

Dr. Angela Stufano
Dr. Claudia Maria Trombetta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vector-borne diseases
  • vaccination strategies
  • epidemiology
  • public health integration
  • disease prevention

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Published Papers (1 paper)

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Review

16 pages, 1336 KiB  
Review
Malaria Vaccines: Current Achievements and Path Forward
by Jiayan Chen, Qi Wang, Xiaomeng He and Bei Yang
Vaccines 2025, 13(5), 542; https://doi.org/10.3390/vaccines13050542 - 19 May 2025
Viewed by 355
Abstract
Malaria remains a significant global health challenge. Although the recent approval of the liver-stage vaccines RTS, S and R21 marks significant progress in malaria control, challenges remain in achieving long-lasting and broad protection. In this review, we provide an overview of the current [...] Read more.
Malaria remains a significant global health challenge. Although the recent approval of the liver-stage vaccines RTS, S and R21 marks significant progress in malaria control, challenges remain in achieving long-lasting and broad protection. In this review, we provide an overview of the current landscape of malaria control, especially anti-malaria vaccine development. We first review the development of the RTS, S and R21 vaccines, highlighting their efficacy and limitations. We then examine other vaccines in development, including attenuated whole-sporozoite vaccines, as well as blood-stage-targeting vaccines and transmission-blocking vaccines targeting a variety of different immunogens. Additionally, we discuss emerging technologies, such as mRNA-based platforms, nanoparticle delivery systems, and novel adjuvants, assessing their potential to enhance the efficacy and mitigate the waning immunity concerns of most malaria vaccines. We believe that the identification of novel immunogen candidates, together with continued innovation in vaccine design and delivery, will enable us to win the fight against malaria in the future. Full article
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