Strategies for Addressing Vaccine Hesitancy

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines and Public Health".

Deadline for manuscript submissions: closed (31 August 2025) | Viewed by 3234

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Center for AIDS Health Disparities Research, Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA
Interests: Zika virus pathobiology; cytomegalovirus pathobiology and vaccines; COVID-19 vaccines and health disparities; monkeypox; emerging pathogens
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Special Issue Information

Dear Colleagues,

Vaccine hesitancy, or the delay in accepting or refusing vaccines despite the availability of vaccination services, is a significant contributor to health disparities. Vaccine hesitancy is often caused by misinformation and disinformation, especially among medically underserved populations and those with low levels of health literacy. Vaccine awareness and education are important. Combating misinformation; supporting health literacy; vaccine access; vaccine champions for training, education, and advocacy; and innovative learning strategies can surmount vaccine hesitancy. This Special Issue will focus on laboratory and clinical vaccine research, utilization, and immunization strategies to reduce vaccine hesitancy, which may include long-term, cost-effective approaches to reduce vaccine-preventable disease burden. Circumstances within the scope of Vaccines that affect vaccine complacency, convenience, and confidence are of interest.

Dr. Donald J. Alcendor
Guest Editor

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Keywords

  • vaccines
  • vaccine hesitancy
  • vaccine uptake
  • vaccine misinformation
  • vaccine disparities

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Published Papers (1 paper)

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22 pages, 457 KB  
Systematic Review
Utilization of Provider–Patient Communication Tools and Approaches to Facilitate Vaccine Confidence: A Systematic Review
by Aleda M. H. Chen, Juanita A. Draime, Mia Engert, Aaron Pachucki, Thurein Zan, Eliya Craig, Nathan Gibson, Chukwunonso Chukwuemeka, Stephanie M. Tubb and Justin W. Cole
Vaccines 2025, 13(11), 1121; https://doi.org/10.3390/vaccines13111121 - 31 Oct 2025
Viewed by 2308
Abstract
Background/Objectives: With declining vaccine coverage and rising concerns regarding vaccines, vaccine-preventable diseases are rising. Many research studies have examined approaches to enhance the acceptance of vaccines, but the integration of these approaches into practice has been limited. Thus, the objective was to [...] Read more.
Background/Objectives: With declining vaccine coverage and rising concerns regarding vaccines, vaccine-preventable diseases are rising. Many research studies have examined approaches to enhance the acceptance of vaccines, but the integration of these approaches into practice has been limited. Thus, the objective was to identify recent evidence surrounding provider–patient communication tools and approaches related to vaccination confidence. Methods: A systematic review following PRISMA methodology was conducted. Using a pre-specified search strategy aligned with the research objective and performed in PubMed, CINAHL, and Web of Science, articles were evaluated by two researchers independently, with a third resolving discrepancies, at the title and abstract screening, full-text review, quality assessment, and data extraction phases. Extraction data were descriptively analyzed, including the impact on vaccine acceptance, and synthesized thematically. Results: From the 2291 studies which underwent screening, a total of, 143 articles were included. Most studies were conducted in the United States, in the outpatient setting, and utilized physicians and nurses to deliver the intervention. Many vaccines were covered, with the greatest number of studies focusing on influenza, HPV, and pneumococcal vaccines. The three predominant communication approaches and tools utilized were provider-focused training, direct patient education/materials, and provider–patient communication strategies. These strategies often focused on addressing knowledge gaps, health beliefs, and common concerns. Over two-thirds of studies increased vaccine acceptance following communication interventions. Conclusions: To address vaccine concerns, it is important to ensure providers have the education and training necessary as well as tools to address underlying causes of concerns. When equipped, providers are able to improve vaccine acceptance. Full article
(This article belongs to the Special Issue Strategies for Addressing Vaccine Hesitancy)
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