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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gastrointestinal Cancer: Outcomes and Therapeutic Management

edited by Maximos Frountzas

submission deadline 20 Aug 2025 | 8 articles | Viewed by 13724 | Submission Open

Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm

(This special issue belongs to the Section Oncology)

Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases

edited by

Reem Hanna

submission deadline 20 Aug 2025 | 5 articles | Viewed by 10748 | Submission Open

Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction

Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research

edited by

Andrew Fu Wah Ho

submission deadline 20 Aug 2025 | 5 articles | Viewed by 8496 | Submission Open

Keywords: cardiovascular emergencies; neurovascular emergencies; stroke; cardiac arrest; acute myocardial infarction

(This special issue belongs to the Section Cardiovascular Medicine)

Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation

edited by

Katja E. Wartenberg

and Lori Shutter

submission deadline 20 Aug 2025 | 4 articles | Viewed by 7321 | Submission Open

Keywords: traumatic brain injury; neuromonitoring; neurocritical care; neurorehabilitation; secondary injury; outcome; prognostication

(This special issue belongs to the Section Brain Injury)

Recent Developments in Gynecological Endocrinology

edited by

Błażej Męczekalski

submission deadline 20 Aug 2025 | 5 articles | Viewed by 6380 | Submission Open

Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause

(This special issue belongs to the Section Obstetrics & Gynecology)

Frailty in the Elderly: Risk Factors, Prevention and Clinical Management

edited by

Gad Segal

submission deadline 20 Aug 2025 | 4 articles | Viewed by 5342 | Submission Open

Keywords: sarcopenia; frailty; elderly; geriatrics; personalized medicine

(This special issue belongs to the Section Epidemiology & Public Health)

New Advances in Prenatal Diagnosis and Newborn Screening

edited by

Zoltan Kozinszky

and

Andrea Suranyi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4736 | Submission Open

Keywords: sonographic parameters; molecular markers; extravillous and villous trophoblasts; perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions

(This special issue belongs to the Section Obstetrics & Gynecology)

Interstitial Lung Disease: From Diagnosis to Treatment

edited by

Takeshi Saraya

and Tomohisa Baba

submission deadline 20 Aug 2025 | 2 articles | Viewed by 3641 | Submission Open

Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds

(This special issue belongs to the Section Respiratory Medicine)

Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections

edited by

Juan J. Segura-Egea

and

Daniel Cabanillas-Balsera

submission deadline 20 Aug 2025 | 5 articles | Viewed by 3381 | Submission Open

Keywords: dentistry; endodontics; apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Kidney Transplantation

edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López

submission deadline 20 Aug 2025 | 4 articles | Viewed by 3241 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Salivary Gland Disorders

edited by Masao Yagi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 2251 | Submission Open

Keywords: salivary gland tumour; parotidectomy; nerve monitoring; molecular-targeted therapy; immunotherapy

(This special issue belongs to the Section Otolaryngology)

Liver Transplantation: Current Hurdles and Future Perspectives

edited by

Gabriele Spoletini

submission deadline 20 Aug 2025 | 3 articles | Viewed by 2072 | Submission Open

Keywords: machine perfusion; donation after circulatory death; liver preservation; living donation; acute-on-chronic liver failure; frailty; liver malignancies; surgical technique; liver transplant recipient care; immunosuppression

(This special issue belongs to the Section General Surgery)

Multiple Sclerosis: Prediction, Diagnosis and Treatment

edited by Rosaria Sacco

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2020 | Submission Open

Keywords: neurological diseases; multiple sclerosis; prodromal symptoms; diagnosis; treatment

(This special issue belongs to the Section Clinical Neurology)

State of the Art in Invasive Vascular Interventions (Second Edition)

edited by

Edit Dósa

and Luca Mezzetto

submission deadline 20 Aug 2025 | 3 articles | Viewed by 1776 | Submission Open

Keywords: coronary artery interventions; non-coronary artery cardiac interventions; open surgical cardiac procedures; endo-vascular interventions; open surgical vascular procedures

(This special issue belongs to the Section Vascular Medicine)

Advancements and Challenges in Managing Hepato-Pancreato-Biliary Cancers

edited by

Alessandro D. Mazzotta

and Niccolò Petrucciani

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1374 | Submission Open

Keywords: liver; pancreas; HPB technology; artificial intelligence for HPB; surgical oncology; MIS

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Juvenile Idiopathic Arthritis (JIA): Diagnosis, Treatment and Latest Updates

edited by

Rita Consolini

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1299 | Submission Open

Keywords: juvenile idiopathic arthritis; pathophysiology; genetic predisposition; immunologic abnormalities; diagnosis; treatment; outcome

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Gastrointestinal Inflammation

edited by

Ivana Jukic

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1262 | Submission Open

Keywords: Helicobacter pylori; antibiotic resistance; COVID-19 pandemic; post-COVID era; inflammatory bowel diseases; acute gastrointestinal infections; SARS-COV-2 infection; celiac disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates in Trauma and Emergency Medicine

edited by Yong-Soo Cho and Hyun Ho Ryu

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1007 | Submission Open

Keywords: emergency medicine; epidemiology; cardiovascular disease

(This special issue belongs to the Section Emergency Medicine)

Mental Disorders, Cognitive Impairment and Dementia Among Older Adults

edited by

Agustín Aibar Almazán

submission deadline 20 Aug 2025 | 1 articles | Viewed by 979 | Submission Open

Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function

(This special issue belongs to the Section Geriatric Medicine)

Cardio-Oncology: Novel Concepts in Diagnosis, Prevention and Treatment of Cardiotoxicity, from Gender Differences and Beyond (Second Edition)

edited by

Sabina Gallina

and

Valentina Bucciarelli

submission deadline 20 Aug 2025 | 1 articles | Viewed by 970 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; gender medicine; chemotherapy; radiotherapy; immune and targeted therapeutics; physical activity; quality of life

(This special issue belongs to the Section Cardiovascular Medicine)

Neurosurgery: Recent Advances and New Perspectives in Skull Base Approaches

edited by Sèbastien Froelich and Matteo De Simone

submission deadline 20 Aug 2025 | 1 articles | Viewed by 680 | Submission Open

Keywords: skull base; neuroanatomy; tumors; augmented reality; ETOA; EEA; exoscopy; endoscopy; multi-portal approaches

(This special issue belongs to the Section Clinical Neurology)

Surgical Precision: The Impact of AI and Robotics in General Surgery

edited by Tamara M. H. Gall

submission deadline 20 Aug 2025 | Viewed by 282 | Submission Open

Keywords: robotic surgery; artificial intelligence in surgery; surgical training; AR in surgery; 3D imaging; surgical navigation

(This special issue belongs to the Section General Surgery)

Diabetic Nephropathy: Advances in Pathogenesis and Novel Therapies

edited by Meritxell Ibernon

submission deadline 20 Aug 2025 | Viewed by 282 | Submission Open

Keywords: pathogenesis of diabetic nephropathy; novel therapies; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification

(This special issue belongs to the Section Nephrology & Urology)

Non-Invasive Respiratory Support: Current Insights and Future Directions

edited by Giovanni Misseri and

Cesare Gregoretti

submission deadline 20 Aug 2025 | Viewed by 183 | Submission Open

Keywords: respiratory failure; high-flow nasal cannula (HFNC); noninvasive ventilation (NIV); noninvasive positive pressure ventilation (NPPV); hypoxia; perioperative care; weaning; ICU; respiratory care; respiratory physiology; pneumology; home-care ventilation; artificial intelligence; personalized medicine

(This special issue belongs to the Section Respiratory Medicine)

Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights

edited by Scott G. Ravyts and Margot De Kooning

submission deadline 20 Aug 2025 | Viewed by 179 | Submission Open

Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma

(This special issue belongs to the Section Mental Health)

Idiopathic Pulmonary Fibrosis (IPF): Current Perspectives and Future Directions

edited by Vito D’Agnano

submission deadline 20 Aug 2025 | Viewed by 157 | Submission Open

Keywords: pulmonary fibrosis; IPF; ILD; antifibrotics; EMT; respiratory physiology; metabolism

(This special issue belongs to the Section Respiratory Medicine)

Management of Pregnancy Complications: 2nd Edition

edited by Ariel Many

submission deadline 20 Aug 2025 | Viewed by 141 | Submission Open

Keywords: high-risk pregnancy; preterm labor; fetal growth restriction; gestational diabetes; twins; hypertensive disorders during pregnancy; preeclampsia; IUGR; prenatal genetics; congenital anomaly detection; cesarean section; complications of labor and delivery

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advancements in Preoperative Optimization for Patients Undergoing Colorectal Surgery

edited by Tim Lubbers

submission deadline 20 Aug 2025 | Viewed by 120 | Submission Open

Keywords: preoperative optimization; colorectal surgery; postoperative recovery; complication; clinical innovations; patient outcome

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Catheter Ablation for Cardiac Arrhythmias: Clinical Updates and Perspectives in Cardiac Electrophysiology

edited by Karolina Weinmann-Emhardt, Ingo Staudacher and Jonas Wormann

submission deadline 21 Aug 2025 | 1 articles | Viewed by 2567 | Submission Open

Keywords: electrophysiology; arrhythmia; atrial fibrillation; atrial flutter; ablation; 3D mapping; pulsed field ablation; radiofrequency ablation; pulmonary vein isolation

(This special issue belongs to the Section Cardiovascular Medicine)

Eosinophilic Esophagitis: Clinical Advances in Diagnosis, Treatment, and Monitoring

edited by Pierfrancesco Visaggi, Edoardo Vincenzo Savarino and

Nicola De Bortoli

submission deadline 21 Aug 2025 | 1 articles | Viewed by 1041 | Submission Open

Keywords: eosinophilic esophagitis (EoE); diagnosis ; treatment ; monitoring; disease assessment; precision medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Acute Pancreatitis: Clinical Management and Treatment

edited by

Sorin Traian Barbu

and

Valeriu Surlin

submission deadline 21 Aug 2025 | Viewed by 220 | Submission Open

Keywords: acute pancreatitis; classification; complications; intervention; management; prevention; severity; treatment

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Acute and Chronic Heart Failure: Clinical Updates and Perspectives

edited by Luigi Cappannoli and Cristina Aurigemma

submission deadline 25 Aug 2025 | 6 articles | Viewed by 10855 | Submission Open

Keywords: acute heart failure; chronic heart failure; devices; drugs therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease

(This special issue belongs to the Section Cardiovascular Medicine)

More than Skin Deep—Latest Advances in Congenital and Autoimmune Pigmentation Disorders

edited by

Reinhart M. Speeckaert

submission deadline 25 Aug 2025 | 1 articles | Viewed by 9341 | Submission Open

Keywords: dermatology; congenital pigmentation disorders; autoimmune pigmentation disorders; melanoma; vitiligo; skin problems; systemic diseases; alopecia areata; wound care

(This special issue belongs to the Section Dermatology)

Myocardial Infarction: Current Status and Future Challenges

edited by Isaac Pascual and

Rebeca Lorca

submission deadline 25 Aug 2025 | 7 articles | Viewed by 9237 | Submission Open

Keywords: myocardial infarction; acute coronary syndrome (ACS); ischemic heart disease; coronary artery disease (CAD); percutaneous coronary intervention; pharmacological therapy; cardiovascular risk factors

(This special issue belongs to the Section Cardiology)

Musculoskeletal Imaging and Intervention

edited by

Miguel Malo-Urriés

and

Jacobo Rodríguez-Sanz

submission deadline 25 Aug 2025 | 5 articles | Viewed by 8864 | Submission Open

Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Directions for Treatment and Assessment of Ulcerative Colitis

edited by

Andrea van der Meulen

and

Christian Selinger

submission deadline 25 Aug 2025 | 3 articles | Viewed by 6860 | Submission Open

Keywords: treatment; ulcerative colitis; treatment target; ultrasound assessment; approach

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Emerging Therapies and Strategies in Thalassemia: Toward a New Era in Management—2nd Edition

edited by

Paolo Ricchi

and Raffaella Origa

submission deadline 25 Aug 2025 | 4 articles | Viewed by 5940 | Submission Open

Keywords: HSCT; gene therapy; new drugs; iron chelation; aging; long-term observation; biomarkers; new strategies

(This special issue belongs to the Section Hematology)

Interventional Pulmonology: Advances and Future Directions

edited by Martina Ferioli and Piero Candoli

submission deadline 25 Aug 2025 | 4 articles | Viewed by 4842 | Submission Open

Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging

(This special issue belongs to the Section Respiratory Medicine)

(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition

edited by

Pietro Muratori

and

Valentina Levantini

submission deadline 25 Aug 2025 | 3 articles | Viewed by 4483 | Submission Open

Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders

(This special issue belongs to the Section Mental Health)

Clinical Challenges in Heart Failure Management

edited by Paolo Severino and Gaetano M. Ruocco

submission deadline 25 Aug 2025 | 5 articles | Viewed by 4421 | Submission Open

Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care

(This special issue belongs to the Section Cardiology)

Multidisciplinary Endocarditis Perspectives: 2nd Edition

edited by

Giovanni La Canna

submission deadline 25 Aug 2025 | 2 articles | Viewed by 3983 | Submission Open

Keywords: endocarditis; clinical diagnostic; multimodality imaging; cardiology; clinical phenotypes

(This special issue belongs to the Section Cardiovascular Medicine)

Cystic Fibrosis: Clinical Manifestations and Treatment

edited by

Laura Trandafir

and

Lǎcrǎmioara Ionela Butnariu

submission deadline 25 Aug 2025 | 4 articles | Viewed by 3900 | Submission Open

Keywords: cystic fibrosis; modifier genes; CFTR modulator; CF newborn screening; CF nutrition; CF complications

(This special issue belongs to the Section Respiratory Medicine)

Challenges in the Field of Psycho-Oncology: Insights from Research

edited by

Ana Bartolo

Sara Monteiro

, Tânia Brandão and Ricardo Teixeira

submission deadline 25 Aug 2025 | 2 articles | Viewed by 3845 | Submission Open

Keywords: cancer; psycho-oncology; survivorship care; psychological distress; quality of life; sustainable development goals; global health; health disparities

(This special issue belongs to the Section Oncology)

New Insights into Lung Imaging

edited by

Chiara Romei

submission deadline 25 Aug 2025 | 3 articles | Viewed by 3389 | Submission Open

Keywords: lung disease; lung cancer; chest-CT; chest X-ray; imaging

(This special issue belongs to the Section Respiratory Medicine)

Navigating Pregnancy and Its Complications: Challenges and Innovations in Maternal–Fetal Medicine

edited by

Nikolaos Machairiotis

submission deadline 25 Aug 2025 | 3 articles | Viewed by 2620 | Submission Open

Keywords: pregnancy; obstetrics; diabetes; high risk; preeclampsia; labor; delivery; hypertension; hemorrhage; embryo; screening

(This special issue belongs to the Section Obstetrics & Gynecology)

Preeclampsia and Other Pregnancy Complications: Early Intervention, Diagnosis and Management

edited by

Kornelia Zaręba

Aneta Słabuszewska-Jóźwiak

and Mohamed Ahmed Mostafa Aboellail

submission deadline 25 Aug 2025 | 2 articles | Viewed by 2284 | Submission Open

Keywords: preeclampsia; pregnancy complications; early intervention; diagnosis of pregnancy complications; management of pregnancy complications; sexual dysfunctions in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Gastrointestinal Diseases: Clinical Challenges and Management

edited by Anusha Shirwaikar Thomas and

Yinghong Wang

submission deadline 25 Aug 2025 | 2 articles | Viewed by 2192 | Submission Open

Keywords: GI bleed; nutrition; obstructive jaundice; drug-induced live injury; GI motility; clostridium difficile infection; large bowel obstruction; colon cancer prevention and surveillance

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advancing Pediatric Sports Medicine: Insights and Innovations

edited by Brian C. Lau

submission deadline 25 Aug 2025 | 3 articles | Viewed by 2029 | Submission Open

Keywords: sport surgery; patellar instability; early sport specialization; triplane fractures; pediatric sports medicine; orthopedic surgery; access to care; arthroscopic

(This special issue belongs to the Section Orthopedics)

Psoriasis and Psoriatic Arthritis: How to Treat in the Era of Biologics and Small Molecule Inhibitors: 3rd Edition

edited by

Mayumi Komine

and

Takemichi Fukasawa

submission deadline 25 Aug 2025 | 1 articles | Viewed by 1945 | Submission Open

Keywords: psoriasis; psoriatic arthritis; biologics; small molecule inhibitors; conventional therapies

(This special issue belongs to the Section Dermatology)

Recent Advances in Immunotherapy of Cancer

edited by

Jessica Chacon