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Coronary Artery Bypass Grafting: Contemporary Clinical Research Update

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 June 2026 | Viewed by 195

Special Issue Editor


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Guest Editor
Department of Cardiothoracic Surgery, Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
Interests: cardiothoracic surgery; robotic surgery; coronary revascularization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Coronary artery bypass grafting (CABG) remains the cornerstone of surgical revascularization. This Special Issue, titled “Coronary Artery Bypass Grafting: Contemporary Clinical Research Update,” will highlight recent clinical evidence that advances patient selection, perioperative management, procedural strategies, and long-term outcomes. We invite the submission of original research and high-quality analyses addressing contemporary topics such as multi-arterial grafting (including bilateral internal thoracic and radial conduits), off-pump and minimally invasive/robotic approaches, and enhanced recovery and perioperative care pathways.

We particularly welcome studies focused on graft durability and patency, including intraoperative assessment, postoperative imaging and surveillance, anastomotic devices/technology, and optimization of antithrombotic and secondary prevention strategies. Submissions using randomized trials, real-world registries, and modern analytic methods (including risk prediction and stratification) are encouraged.

We are especially interested in works involving complex and under-studied patient subsets—such as diabetes, left main or multivessel disease, reduced ejection fraction, frailty, and women’s cardiovascular health—as well as contemporary comparisons of CABG with PCI, and studies of hybrid or staged revascularization strategies. Our goal is to provide clinicians and researchers with practical, data-driven insights that improve durable revascularization and patient-centred outcomes.

Dr. Arian Arjomandi Rad
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coronary artery bypass grafting
  • arterial grafts
  • graft patency
  • hybrid coronary revascularization
  • perioperative management
  • outcomes research
  • risk stratification
  • frailty
  • minimally invasive/robotic CABG
  • antithrombotic therapy

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Published Papers (1 paper)

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Research

17 pages, 2057 KB  
Article
Winter Temperature and Long-Term Mortality After Coronary Artery Bypass Grafting: A Multicenter Cohort Study
by Tomasz Urbanowicz, Sleiman Sebastian Aboul-Hassan, Krzysztof Skotak, Maria Luszczyn, Łukasz Moskal, Jakub Bratkowski, Jarosław Bartkowski, Bartłomiej Perek, Mirosław Wilczyński, Krzysztof J. Filipiak, Romuald Cichoń and Marek Jemielity
J. Clin. Med. 2026, 15(11), 4216; https://doi.org/10.3390/jcm15114216 - 29 May 2026
Abstract
Background: Traditional cardiovascular risk models focus on patient-related clinical variables, while the impact of long-term environmental exposure remains insufficiently characterized in post-revascularization populations. Objective: To evaluate the association between environmental exposure and long-term mortality after coronary artery bypass grafting (CABG), and to determine [...] Read more.
Background: Traditional cardiovascular risk models focus on patient-related clinical variables, while the impact of long-term environmental exposure remains insufficiently characterized in post-revascularization populations. Objective: To evaluate the association between environmental exposure and long-term mortality after coronary artery bypass grafting (CABG), and to determine whether integrated environmental measures provide additional prognostic value beyond established clinical risk factors. Methods: This retrospective multicenter cohort study included 1042 consecutive patients undergoing CABG with a median follow-up of 8.1 years. Regional environmental data were linked to individual patients. Multivariable Cox regression models were constructed using a hierarchical approach. To address collinearity among environmental variables, principal component analysis (PCA) was applied. Mean winter temperature was analyzed as a clinically interpretable proxy of overall environmental exposure. Results: During follow-up, 220 deaths (21.1%) occurred. Established clinical predictors of mortality included age, diabetes mellitus, peripheral vascular disease, and dyslipidemia. Individual environmental variables showed unstable associations due to collinearity. PCA identified a dominant environmental component explaining 82.0% of variance; however, its association with mortality did not reach statistical significance after adjustment (HR 1.17 per SD, 95% CI 0.98–1.39; p = 0.083). In contrast, higher mean winter temperature was independently associated with increased mortality (HR 1.24 per SD, 95% CI 1.05–1.48; p = 0.013) per 1 °C increase, with evidence of non-linearity. Conclusions: Environmental exposure represents a relevant component of long-term risk after CABG. While individual environmental variables are highly correlated and unstable, clinically interpretable measures such as winter temperature may provide practical support for risk assessment. Full article
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