Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets

Dear Colleagues,

Metabolic dysfunction-associated steatotic liver disease (MASLD) covers the wide spectrum of steatotic liver disease. It has become a major cause of liver-related morbidity and mortality worldwide and one of the most common indications for liver transplantation. Nevertheless, hepatic injury is not the only health problem in the course of the disease, and comorbidities should also be taken into account. Understanding the multiorgan and systemic impact of metabolic interactions should facilitate holistic patient management by providing exact insights into disease pathogenesis and should help to create better therapeutic strategies in the future.

The present Special Issue aims to highlight the coexistence of major liver, cardiovascular, and cancer threats to disease-affected patients, as well as to address the importance of the early implementation of preventive strategies to hamper disease progression and establish the most effective treatment.

We are pleased and honored to invite researchers to submit all types of papers, including original, narrative, and systematic reviews, to this Special Issue to widen our knowledge of multiorgan metabolic interactions and their implications for human health. 

Prof. Dr. Beata Kasztelan-Szczerbinska
Prof. Dr. Halina Cichoż-Lach
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.