Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Deadline for manuscript submissions: 5 August 2025 | Viewed by 2262
Special Issue Editors
Interests: liver cirrhosis; non-alcoholic fatty liver disease; portal hypertension; liver failure; chronic liver diseases; liver cirrhosis; immune-related liver diseases; alcohol-related liver disease
Interests: chronic liver diseases; liver cirrhosis; alcohol-related liver disease; cholestasis; inflammatory bowel disease; novel markers of liver fibrosis; liver steatosis
Special Issue Information
Dear Colleagues,
Metabolic dysfunction-associated steatotic liver disease (MASLD) covers the wide spectrum of steatotic liver disease. It has become a major cause of liver-related morbidity and mortality worldwide and one of the most common indications for liver transplantation. Nevertheless, hepatic injury is not the only health problem in the course of the disease, and comorbidities should also be taken into account. Understanding the multiorgan and systemic impact of metabolic interactions should facilitate holistic patient management by providing exact insights into disease pathogenesis and should help to create better therapeutic strategies in the future.
The present Special Issue aims to highlight the coexistence of major liver, cardiovascular, and cancer threats to disease-affected patients, as well as to address the importance of the early implementation of preventive strategies to hamper disease progression and establish the most effective treatment.
We are pleased and honored to invite researchers to submit all types of papers, including original, narrative, and systematic reviews, to this Special Issue to widen our knowledge of multiorgan metabolic interactions and their implications for human health.
Prof. Dr. Beata Kasztelan-Szczerbinska
Prof. Dr. Halina Cichoż-Lach
Guest Editors
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Keywords
- metabolic dysfunction-associated steatotic liver disease (MASLD)
- non-alcoholic fatty liver disease (NAFLD)
- hepatic steatosis
- multiorgan metabolic interactions
- liver-related morbidity
- liver-related mortality
- lipid metabolism
- cardiovascular metabolic complications
- metabolic dysfunction-related cancer
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