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Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 2688

Special Issue Editor

Dr. Glauco Chisci

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Guest Editor
Oral Surgery Postgraduate School, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy
Interests: antibiotics; infection; oral surgery; maxillofacial surgery; third molar; dental implants; zygomatic implants; socket preservation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The introduction of advances in oral surgery and periodontology is a matter of interest for both surgeons and researchers. The purpose of this Special Issue is to promote the publication of recent papers showcasing the techniques and innovations in oral and periodontal surgery. This Special Issue in this journal, JCM, aims to extend this topic, ‘Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition’, to the scientific plateau.

Submissions may address the following topics:

  • Advances in oral pathology;
  • Antimicrobial and antibiotics therapy;
  • Oral manifestations of systemic pathology;
  • Third molar surgery;
  • Periodontal disease and surgery;
  • Complications and management;
  • Ecological prescription of antibiotics in oral and maxillofacial surgery;
  • Dental implants and bone regeneration.

Dr. Glauco Chisci
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral surgery
  • third molar
  • periodontitis
  • antibiotics
  • infection
  • pain
  • research
  • advances
  • complications
  • dental implants
  • bone regeneration
  • maxillofacial surgery

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Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (3 papers)

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Research

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19 pages, 1562 KB  
Article
Prevalence and Radiographic Patterns of Impacted Third Molars in a Portuguese Population: A Retrospective Orthopantomography (OPG) and Cone-Beam Computed Tomography (CBCT) Study
by Ana Catarina Pinto, Helena Francisco, Maria Inês Charro, Duarte Marques, Jorge N. R. Martins and João Caramês
J. Clin. Med. 2026, 15(3), 1160; https://doi.org/10.3390/jcm15031160 - 2 Feb 2026
Viewed by 662
Abstract
Background/Objectives: Impacted third molars are frequent and may increase surgical complexity, particularly when the mandibular third molar is in close proximity to the inferior alveolar canal (IAC). This study aimed to estimate the prevalence and impaction patterns of third molars in a Portuguese [...] Read more.
Background/Objectives: Impacted third molars are frequent and may increase surgical complexity, particularly when the mandibular third molar is in close proximity to the inferior alveolar canal (IAC). This study aimed to estimate the prevalence and impaction patterns of third molars in a Portuguese population and to characterize, using a nested CBCT subsample, the three-dimensional relationship between mandibular third molars and the IAC, including cortical integrity and lingual plate thickness. Methods: A retrospective observational analysis of 1062 orthopantomograms (OPGs) was performed to determine the prevalence and panoramic patterns using Winter, Pell and Gregory classifications and Rood–Shehab signs. A consecutive CBCT subsample (n = 205) was assessed for IAC position, contact status (no contact; contact with cortical bone; contact without cortical bone), cortical integrity, and lingual plate thickness. Descriptive statistics were complemented by effect sizes to support clinical interpretability. Results: The prevalence of impacted third molars was 34.9%, occurring predominantly in the mandible. Vertical angulation was the most prevalent pattern in both jaws. In the CBCT subsample, IAC position and contact patterns varied widely, and loss of cortical integrity was more often observed when panoramic high-risk signs were present. No clinically meaningful left–right asymmetry was identified across key anatomical risk indicators. Conclusions: In this Portuguese cohort, impacted third molars showed consistent panoramic patterns, while CBCT provided clinically relevant three-dimensional risk descriptors—particularly IAC contact type and cortical integrity—supporting selective CBCT use based on anatomical risk indicators rather than routine imaging. Full article
(This article belongs to the Special Issue Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition)
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14 pages, 1003 KB  
Article
Impact of the COVID-19 Pandemic on Odontogenic Abscess Clinical Patterns and Predictive Factors: A Retrospective Cross-Sectional Study
by Kacper Nijakowski, Stanisław Ksel, Olesya Marushko, Aleksy Nowak, Jakub Jankowski, Jacek Kwiatkowski, Olena Marushko, Łukasz Słowik and Maciej Okła
J. Clin. Med. 2025, 14(19), 6953; https://doi.org/10.3390/jcm14196953 - 1 Oct 2025
Cited by 1 | Viewed by 995
Abstract
Background/Objectives: The COVID-19 pandemic disrupted healthcare systems globally, with dental services significantly limited due to infection control measures. This study investigates the impact of the pandemic on the clinical presentation, management, and outcomes of odontogenic abscesses over three distinct periods. Methods: [...] Read more.
Background/Objectives: The COVID-19 pandemic disrupted healthcare systems globally, with dental services significantly limited due to infection control measures. This study investigates the impact of the pandemic on the clinical presentation, management, and outcomes of odontogenic abscesses over three distinct periods. Methods: A retrospective study was conducted at University Clinical Hospital (Poznan, Poland), which included adult patients hospitalised for odontogenic infections between March 2019 and February 2022. The cohort comprised 101 patients (median age: 33 years; 59.41% male), with admissions distributed across pre-pandemic (37.62%), pandemic (19.80%), and post-pandemic (42.57%) periods. Clinical, biochemical, and radiographic data were analysed. Results: No statistically significant differences were found between periods for abscess severity, hospitalisation length, or inflammatory marker levels. Elevated procalcitonin (Rs = 0.289, p = 0.005), C-reactive protein (Rs = 0.385, p < 0.001), and body mass index (Rs = 0.253, p = 0.011) independently predicted longer hospital stays. In regression modelling, procalcitonin (β = 0.464, p = 0.001) and prior outpatient antibiotic use (β = 0.281, p = 0.038) were mainly associated with larger abscess volumes, while comorbidities (β = 0.262, p = 0.025), longer hospitalisation (β = 0.594, p = 0.001) and abscess volume (β = −0.294, p = 0.040) increased the risk of reoperation. Conclusions: The study highlights clinically important findings linked to delayed dental care and increased systemic inflammation related to the pandemic. Elevated procalcitonin and CRP levels provide prognostic information that can guide early triage, risk stratification, and decisions regarding surgical versus outpatient management. These findings emphasise the importance of maintaining essential dental services, implementing preventive strategies, and optimising management protocols to reduce the risk of severe infections and improve patient outcomes during healthcare disruptions. Full article
(This article belongs to the Special Issue Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition)
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Other

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13 pages, 3733 KB  
Case Report
Diagnostic Pitfalls of Dental Follicles and Cyst-like Lesions in Juvenile Patients: An Early Odontogenic Myxoma Mimicking a Follicular Cyst
by Kamil Nelke, Klaudiusz Łuczak, Michał Gontarz, Grażyna Wyszyńska-Pawelec, Agata Małyszek, Ömer Uranbey, Dayel Gerardo Rosales Díaz Mirón, Maciej Dobrzyński, Małgorzata Tarnowska and Piotr Kuropka
J. Clin. Med. 2026, 15(2), 599; https://doi.org/10.3390/jcm15020599 - 12 Jan 2026
Viewed by 567
Abstract
The occurrence of cysts and tumors in pediatric patients varies across different age groups. Follicular and dentigerous cysts are among the most common lesions. However, typical odontogenic tumors in juvenile patients are not frequently observed. Early stages of cyst and odontogenic tumor development [...] Read more.
The occurrence of cysts and tumors in pediatric patients varies across different age groups. Follicular and dentigerous cysts are among the most common lesions. However, typical odontogenic tumors in juvenile patients are not frequently observed. Early stages of cyst and odontogenic tumor development might exhibit some similar characteristics due to the presence of unerupted teeth or their relationship with various stages of tooth formation and eruption. Many small lesions are discovered accidentally on routine orthopantomography (OPG), while the bigger ones manifest themselves as bone swelling, cortical perforation, or displacement and mobility of teeth. Each odontogenic tumor has characteristic clinical and radiological features. Biopsy of larger lesions, or incisional biopsy of smaller lesions, allows detailed histopathological evaluation to determine tumor type and growth behavior and guide appropriate treatment planning. In some cases, atypical signs on OPGs, like asymmetry in dental follicles, occurrence of round or oval bone lesions near impacted or retained teeth, and visibility of irregular radiolucent, radiopaque, or mixed jawbone lesions, might suggest the occurrence of some possible odontogenic tumor in juvenile patients. Each case should be handled individually. In this case, we demonstrate how atypical appearances of dental follicles on panoramic radiographs may not correspond with cone-beam computed tomography findings and may indicate the early stages of odontogenic myxoma in a juvenile patient. Full article
(This article belongs to the Special Issue Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition)
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