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Clinical Advances in Spine Disorders—2nd Edition
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Clinical Advances in Spine Disorders—2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 10 July 2026 | Viewed by 1299

Special Issue Editors

Dr. Sokol Trungu

E-Mail Website
Guest Editor
1. Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy
2. Neurosurgery Unit, Cardinale G. Panico Hospital, 73039 Tricase, Italy
Interests: spinal surgery; spinal cord injury; spine surgery; microneurosurgery; neuro-oncology; glioma; traumatic brain injury; neuroanatomy; brain tumors; intervertebral disk degeneration
Special Issues, Collections and Topics in MDPI journals
Dr. Luca Ricciardi

E-Mail Website
Guest Editor
Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy
Interests: spine surgery; spinal surgery; spinal cord injury; microneurosurgery; neuroanatomy; brain injury; traumatic brain injury; glioma; spine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce the Special Issue “Clinical Advances in Spine Disorders—2nd Edition”, building upon the success of the first edition.

Clinical advances and surgical techniques for the treatment of spine disorders have been effective in minimizing invasiveness and reducing complications. However, there is always a need for improvements in patient outcomes based on new insights and the latest developments in lumbar spine surgery. In this Special Issue of Journal of Clinical Medicine, we are interested in providing a comprehensive overview of the latest advances in the development of conservative treatments and surgical techniques, with a focus on minimally invasive surgery and the use of robotics and navigation systems.

We invite authors to submit papers to this Special Issue focusing on the newest clinical advances in spine disorders. We hope that this Special Issue will reignite interest in the currently unsolved challenges encountered in spine surgery.

Dr. Sokol Trungu
Dr. Luca Ricciardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spine disorders
  • lumbar spine surgery
  • minimally invasive surgery
  • spine surgery
  • microneurosurgery

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Published Papers (1 paper)

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12 pages, 831 KB  
Systematic Review
Complications in Thoracic Minimally Invasive Spine Surgery (2013–2024): A Systematic Review
by Sean Inzerillo, Chibuikem A. Ikwuegbuenyi, Eesha Gurav, Noah Willett, Mousa Hamad, Ibrahim Hussain, Alan Hernández-Hernández, Galal Elsayed, Osama Kashlan and Roger Härtl
J. Clin. Med. 2026, 15(1), 363; https://doi.org/10.3390/jcm15010363 - 3 Jan 2026
Viewed by 968
Abstract
Background/Objectives: Thoracic minimally invasive spine surgery (MISS) offers reduced tissue trauma and faster recovery compared with open approaches, but its adoption remains limited due to technical complexity and uncertainty regarding complication rates. This study aimed to synthesize the available evidence on overall [...] Read more.
Background/Objectives: Thoracic minimally invasive spine surgery (MISS) offers reduced tissue trauma and faster recovery compared with open approaches, but its adoption remains limited due to technical complexity and uncertainty regarding complication rates. This study aimed to synthesize the available evidence on overall and approach-specific complications of thoracic MISS using tubular, uniportal endoscopic, and biportal endoscopic techniques. Methods: Following PRISMA guidelines (PROSPERO CRD42024594316), PubMed, Medline, Embase, and Cochrane Library were searched from January 2013 to March 2024 for studies reporting complication rates after thoracic MISS in adults. Eligible studies included tubular, uniportal, or biportal approaches. Study quality was assessed using the Newcastle–Ottawa Scale. Complication data were extracted and summarized descriptively, with reported rates stratified by surgical approach. Results: Nine studies (234 patients) were included, all retrospective with moderate risk of bias. Across included studies, reported overall complication rates following thoracic MISS ranged from 0% to 42.9%. Stratified by surgical approach, reported complication rates ranged from 0% to 11.8% across six tubular studies, 9.7% to 20.0% across two uniportal endoscopic studies, and 42.9% in a single small biportal endoscopic study. Neural injuries and dural tears were the most frequently reported complications, with reported rates ranging from 0% to 14.3% and 0% to 3.6%, respectively. Symptomatic cerebrospinal fluid leaks and revision surgeries were less common, with reported rates ranging from 0% to 11.8% and 0% to 3.2%, respectively. Conclusions: Thoracic MISS demonstrates a low overall complication rate, particularly for tubular approaches. However, findings should be interpreted with caution given the small number of included studies, retrospective designs, and clinical heterogeneity. Larger comparative investigations are needed to better define safety profiles and support broader adoption of thoracic MISS techniques. Full article
(This article belongs to the Special Issue Clinical Advances in Spine Disorders—2nd Edition)
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