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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Femtosecond Laser Applications
edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts
submission deadline 20 Dec 2025 | 4 articles | Viewed by 4033 | Submission Open
Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract
(This special issue belongs to the Section Ophthalmology)
Clinical Investigations into Diagnosing and Managing Strabismus
edited by Mario Cantó Cerdán and Pilar Cacho-Martínez
submission deadline 20 Dec 2025 | 3 articles | Viewed by 3908 | Submission Open
Keywords: oculomotricity; binocular vision; strabismus; ocular motility disorders; exotropia; esotropia; video oculography; eye tracker; ocular deviation
(This special issue belongs to the Section Ophthalmology)
Colorectal Surgery: Current Practice and Future Perspectives
edited by
submission deadline 20 Dec 2025 | 2 articles | Viewed by 3882 | Submission Open
Keywords: colorectal surgery; minimal invasive surgery; open surgery; robot assisted surgery; colorectal cancer; stomach cancer; pancreatic cancer; diverticular disease
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Management of Burns: Past, Present and Future
edited by Lior Rosenberg
submission deadline 20 Dec 2025 | 2 articles | Viewed by 3719 | Submission Open
Keywords: history of burn care; burn care infection; inflammation; burn wound care and closure; debridement; traditional Chinese burn care; traditional Indian (Ayurveda) burn care; burn mass casualty incidents (BMCIs); surge capacity; burn pain control; pruritus; burn scar treatment
(This special issue belongs to the Section General Surgery)
Advances in Periodontitis and Other Periodontal Diseases
edited by
submission deadline 20 Dec 2025 | 4 articles | Viewed by 3522 | Submission Open
Keywords: periodontal diseases; gingivitis; periodontitis; systemic disease; classification
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Updates on the Clinical Applications of Dental Restorative Materials
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 3101 | Submission Open
Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Multiple Sclerosis: Clinical Advances in Diagnosis and Treatment
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 3061 | Submission Open
Keywords: relapse-remitting multiple sclerosis; progressive multiple sclerosis; immunomodulatory treatments; cognitive impairment; personalized medicine in multiple sclerosis
(This special issue belongs to the Section Clinical Neurology)
Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation submission deadline 20 Dec 2025 | 2 articles | Viewed by 2786 | Submission Open
Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology
(This special issue belongs to the Section Cardiology)
Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation
edited by Marco Severino
submission deadline 20 Dec 2025 | 1 articles | Viewed by 2578 | Submission Open
Keywords: dental implants; oral rehabilitation; computer-guided surgery; biocompatibility; regenerative treatments; mini-implants; minimally invasive surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Management of Bladder Cancer
edited by , Antonio Cicione and
submission deadline 20 Dec 2025 | 1 articles | Viewed by 2574 | Submission Open
Keywords: bladder cancer; minimally invasive surgery; immunotherapy; targeted therapy; biomarkers; imaging techniques; muscle invasive bladder cancer; non-muscle-invasive bladder cancer
(This special issue belongs to the Section Nephrology & Urology)
Genitourinary Cancers: Clinical Advances and Practice Updates
edited by David Benjamin and Arash Rezazadeh Kalebasty
submission deadline 20 Dec 2025 | 3 articles | Viewed by 2513 | Submission Open
Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology
(This special issue belongs to the Section Nephrology & Urology)
Advances in Diagnosis and Treatment of Urological Cancers
edited by Davide Campobasso, and
submission deadline 20 Dec 2025 | 2 articles | Viewed by 2245 | Submission Open
Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives of Vascular and Endovascular Surgeries submission deadline 20 Dec 2025 | 2 articles | Viewed by 2071 | Submission Open
Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease
(This special issue belongs to the Section Vascular Medicine)
New Insights in Maxillofacial Surgery
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1945 | Submission Open
Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Key Challenges in Heart Transplantation and Their Solutions
edited by Elizabeth J. Maynes
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1683 | Submission Open
Keywords: heart transplantation; heart failure; cardiac surgery; minimally invasive techniques; general surgery; heart diseases
(This special issue belongs to the Section Cardiology)
Current Challenges and Perspectives in Liver Transplantation
edited by Bogdan Dorobanţu, and Waldo Concepcion
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1370 | Submission Open
Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Neurological Rehabilitation: Repair Mechanisms, Plasticity, and Connectomes
edited by Thomas Mokrusch and Frank Kirchhoff
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1346 | Submission Open
Keywords: neurorehabilitation; therapeutic approaches; repair mechanism; plasticity; neurology
(This special issue belongs to the Section Clinical Neurology)
New Perspectives in Maternal–Fetal Medicine
edited by Catalina de Paco-Matallana
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1068 | Submission Open
Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Perspectives and Innovations in Urogynecology
edited by Stavros Athanasiou
submission deadline 20 Dec 2025 | 1 articles | Viewed by 984 | Submission Open
Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life
(This special issue belongs to the Section Obstetrics & Gynecology)
Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 861 | Submission Open
Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse
(This special issue belongs to the Section Cardiology)
New Clinical Advances in Breast Reconstruction
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 674 | Submission Open
Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Novel Diagnostic and Therapeutic Strategies in Vitreoretinal Disease
edited by Jerzy Mackiewicz and
submission deadline 20 Dec 2025 | Viewed by 373 | Submission Open
Keywords: retinal detachment; vitreoretinal diseases; PPV; vitrectomy; macular edema; uveitis; AMD; retinal imaging; retinal pathology; diabetic retinopathy; optical coherent tomography; OCT
(This special issue belongs to the Section Ophthalmology)
Parkinson's Disease: Recent Advances in Diagnosis and Treatment submission deadline 20 Dec 2025 | Viewed by 339 | Submission Open
Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Innovative Treatment and Management Strategies for Inflammatory Bowel Disease
edited by Syed Adeel Hassan and
submission deadline 20 Dec 2025 | Viewed by 326 | Submission Open
Keywords: Crohn’ s disease; ulcerative colitis; efficacy; safety; nutrition; surgery; biomarkers
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Risk Factors in Neonatal Intensive Care submission deadline 20 Dec 2025 | Viewed by 306 | Submission Open
Keywords: neonatal intensive care; infant birth; preterm; neonatal resuscitation; neonatal outcome; growth restriction; prenatal diagnosis; severe maternal pathology and its effects on a newborn; therapeutical hypothermia; parenteral nutrition; neonatal infection; retinopathy of prematurity
(This special issue belongs to the Section Clinical Pediatrics)
Transformative Research in Hydrocephalus: Clinical Advances
edited by Afroditi D. Lalou, Zofia Helena Czosnyka and Marek Czosnyka
submission deadline 20 Dec 2025 | Viewed by 294 | Submission Open
Keywords: cerebrospinal fluid dynamics; CSF shunt; intracranial pressure monitoring; telemetric ICP; hydrocephalus pathophysiology; neuroimaging; paediatric hydrocephalus; adult hydrocephalus; translational neuroscience
(This special issue belongs to the Section Clinical Neurology)
Applications of Artificial Intelligence in Cardiology: New Tools to Transform Care submission deadline 20 Dec 2025 | Viewed by 251 | Submission Open
Keywords: artificial intelligence in cardiology; machine learning; deep learning; AI-driven ECG analysis; cardiovas-cular imaging and AI; predictive analytics in cardiology; mHealth and wearables; clinical decision support systems; ethics and AI in healthcare; digital health and remote monitoring
(This special issue belongs to the Section Cardiology)
Recent Developments in Urinary Incontinence
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 234 | Submission Open
Keywords: urinary incontinence; overactive bladder; stress urinary incontinence; pelvic floor dysfunction; urodynamics; minimally invasive treatment; neuromodulation; regenerative medicine; conservative management; digital health in urology
(This special issue belongs to the Section Nephrology & Urology)
Hospital-Acquired Infections: Insights, Prevention, and Control Strategies
edited by
submission deadline 20 Dec 2025 | Viewed by 201 | Submission Open
Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department
(This special issue belongs to the Section Epidemiology & Public Health)
Surgical Oncology: Clinical Application of Translational Medicine
edited by Domenico Parmeggiani
submission deadline 20 Dec 2025 | Viewed by 198 | Submission Open
Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research
(This special issue belongs to the Section Oncology)
Laparoscopy and Surgery in Gynecologic Oncology: 2nd Edition
edited by Zoltan Novak
submission deadline 20 Dec 2025 | Viewed by 177 | Submission Open
Keywords: gynecologic cancers; ovarian; uterine; cervical; laparoscopy; diagnosis; staging; treatment; palliative care; fertility preservation
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Clinical Management of Temporomandibular Joint Diseases submission deadline 20 Dec 2025 | Viewed by 172 | Submission Open
Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 20 Dec 2025 | Viewed by 169 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current and Emerging Treatment Options in Intestinal and Stomach Neoplasms
edited by Alexandros E. Giakoustidis and
submission deadline 20 Dec 2025 | Viewed by 167 | Submission Open
Keywords: colorectal cancer; colon cancer; gastric carcinoma; malignancy; gastroenterology; endoscopic techniques; therapeutic advancements; intestinal neoplasms
(This special issue belongs to the Section Oncology)
Clinical Research and Insights in Endometriosis
edited by
submission deadline 20 Dec 2025 | Viewed by 163 | Submission Open
Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics
(This special issue belongs to the Section Obstetrics & Gynecology)
Advanced Technologies, Concepts, and Topics in Modern Neurosurgery
edited by and Ralf Stroop
submission deadline 20 Dec 2025 | Viewed by 160 | Submission Open
Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning
(This special issue belongs to the Section General Surgery)
Advances in Lung Transplantation and Interventional Pulmonology
edited by Anupam Kumar and Frye Laura
submission deadline 20 Dec 2025 | Viewed by 155 | Submission Open
Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery
(This special issue belongs to the Section Respiratory Medicine)
The Treatment of BPO with Minimal Invasive Approach
edited by
submission deadline 20 Dec 2025 | Viewed by 154 | Submission Open
Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery
(This special issue belongs to the Section Nephrology & Urology)
Status, Application and Future Directions of Artificial Urinary Sphincters
edited by JiSung Shim
submission deadline 20 Dec 2025 | Viewed by 142 | Submission Open
Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO
(This special issue belongs to the Section Nephrology & Urology)
Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers submission deadline 20 Dec 2025 | Viewed by 112 | Submission Open
Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations in Preeclampsia
edited by Jeffrey M. Denney and
submission deadline 22 Dec 2025 | 3 articles | Viewed by 16177 | Submission Open
Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity
(This special issue belongs to the Section Obstetrics & Gynecology)
Scoliosis: Advances in Diagnosis and Management
edited by Michal Latalski
submission deadline 22 Dec 2025 | 3 articles | Viewed by 4771 | Submission Open
Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life
(This special issue belongs to the Section Orthopedics)
Oral Surgery: Recent Advances and Future Perspectives submission deadline 22 Dec 2025 | 1 articles | Viewed by 4074 | Submission Open
Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects
edited by Maria Chiara Maccarone and
submission deadline 22 Dec 2025 | 2 articles | Viewed by 3927 | Submission Open
Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine
(This special issue belongs to the Section Orthopedics)
Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology
edited by Praveen Peddu
submission deadline 22 Dec 2025 | 1 articles | Viewed by 816 | Submission Open
Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition) submission deadline 22 Dec 2025 | 1 articles | Viewed by 703 | Submission Open
Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 24 Dec 2025 | 2 articles | Viewed by 1072 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Sports Injury: Clinical Prevention and Treatment
edited by , Susana Pulgar and
submission deadline 25 Dec 2025 | 4 articles | Viewed by 25312 | Submission Open
Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV
(This special issue belongs to the Section Sports Medicine)
Skin Diseases: From Diagnosis to Treatment
edited by
submission deadline 25 Dec 2025 | 6 articles | Viewed by 19537 | Submission Open
Keywords: skin; melanoma; NMSC; CTCL; mesenchymal
(This special issue belongs to the Section Dermatology)
Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease
edited by
submission deadline 25 Dec 2025 | 6 articles | Viewed by 14295 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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