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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Movement Disorders: Current Diagnostics, Management and Future Perspectives
edited by and Marianthi A. Arnaoutoglou
submission deadline 25 Dec 2026 | 1 articles | Viewed by 847 | Submission Open
Keywords: neuroimaging; neuromodulation; cell and gene therapy; digital biomarkers; deep learning; artificial intelligence; movement disorders; hypokinetic; hyperkinetic; immune-mediated movement disorders; neurodegenerative movement disorders
(This special issue belongs to the Section Clinical Neurology)
Treatment of Atopic Dermatitis, 2nd Edition
edited by and Ricardo Ruíz-Villaverde
submission deadline 25 Dec 2026 | 1 articles | Viewed by 791 | Submission Open
Keywords: atopic dermatitis; eczema; topical treatment; systemic treatment; biological therapy; JAK inhibitor; antipruritic treatment
(This special issue belongs to the Section Dermatology)
Innovations in ENT Surgical Procedures
edited by , Giuseppe Fancello and
submission deadline 25 Dec 2026 | 1 articles | Viewed by 587 | Submission Open
Keywords: endoscopic sinus surgery; ear surgery; transoral robotic surgery; image-guided navigation; ENT minimally invasive techniques; ENT surgical innovation
(This special issue belongs to the Section Otolaryngology)
Clinical Perspectives in Acne, Rosacea, and Hidradenitis Suppurativa
edited by Marta Szepietowska and Lukasz Matusiak
submission deadline 25 Dec 2026 | 1 articles | Viewed by 527 | Submission Open
Keywords: acne; acneiform eruption; rosacea; hidradenitis suppurativa; clinical perspective; comorbidities; novel pharmacological options; procedural interventions
(This special issue belongs to the Section Dermatology)
Robotic Cardiac Surgery–State of the Art
edited by Borut Geršak, Robert Phillip Gallegos and Michael E.K. Ibrahim
submission deadline 25 Dec 2026 | 1 articles | Viewed by 472 | Submission Open
Keywords: robotic cardiac surgery; minimally invasive cardiac surgery; cardiac robotics; mitral valve surgery; aortic valve surgery; surgical robotics; cardiac surgery training; minimally invasive techniques; robotic technology
(This special issue belongs to the Section Cardiology)
Hepatobiliary and Pancreatic Cancers: Current Solutions and Future Perspectives
edited by and Cătălina Vlăduț
submission deadline 25 Dec 2026 | Viewed by 323 | Submission Open
Keywords: pancreatic neoplasia; pancreatic ductal adenocarcinoma; cholangiocarcinoma; endosonography; ERCP; cholangioscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Quantitative Surface Electromyography for Masticatory and Trigemino-Cervical Assessment: Novel Indices, Diagnostic Accuracy, and Clinical Applications
edited by
submission deadline 25 Dec 2026 | Viewed by 276 | Submission Open
Keywords: surface electromyography; sEMG; masticatory system; trigemino-cervical assessment; clinical applications; cervico-craniofacial disorders; temporomandibular disorders; pain assessment; bruxism
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Trends in Abdominal Surgery
edited by
submission deadline 25 Dec 2026 | Viewed by 243 | Submission Open
Keywords: abdominal surgery; minimally invasive surgery; robotic surgery; gastrointestinal surgery; artificial intelligence in surgery; enhanced recovery after surgery (ERAS)
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Urinary System Dysfunction: Focusing on Neurogenic Lower Urinary Tract Dysfunction and Prostate Diseases
edited by , Marie Aimée Perrouin Verbe and Xavier Biardeau
submission deadline 25 Dec 2026 | Viewed by 218 | Submission Open
Keywords: neurourology; neurogenic bladder; benign prostate hyperplasia; bladder obstruction; lower urinary tract dysfunction; bladder outlet obstruction; prostate cancer; lower urinary tract symptoms
(This special issue belongs to the Section Nephrology & Urology)
Innovations in Valve and Heart Failure Disease
edited by Andrea De Martino and Sandro Sponga
submission deadline 25 Dec 2026 | Viewed by 211 | Submission Open
Keywords: heart failure; aortic diseases; mitral valve; aortic valve; tricuspid valve
(This special issue belongs to the Section Cardiology)
Hepatitis: Clinical Guide to Infection, Complications, and Management
edited by Tarek Saadi and
submission deadline 25 Dec 2026 | Viewed by 209 | Submission Open
Keywords: acute hepatitis; chronic hepatitis; liver inflammation; viral hepatitis; HBV reactivation; immunocompromised host; oncology-associated hepatitis; antiviral therapy; biomarkers; non-invasive fibrosis; HDV; CMV; EBV; HSV; VZV; coinfection
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Sjogren’s Syndrome: Clinical Updates and Perspectives
edited by Caterina Vacchi
submission deadline 25 Dec 2026 | Viewed by 189 | Submission Open
Keywords: Sjogren’s disease; extra-glandular involvement; interstitial lung disease; treatment approach; precision medicine; patient subgrouping; patient-reported outcomes
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Neo-Adjuvnat Treatment and Tumor Microenvironment for Gastrointestinal Cancers
edited by
submission deadline 25 Dec 2026 | Viewed by 180 | Submission Open
Keywords: tumor microenviroment; chronic imflammation; gastrointestinal tumors; conversion surgery; target tumor chemotherapy; immunocheck point inhibitors
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Emerging Trends in Athlete Health: Advanced Monitoring for Injury Prevention and Recovery submission deadline 25 Dec 2026 | Viewed by 144 | Submission Open
Keywords: sport medicine; sports injuries; injury prevention; rehabilitation; athletic performance; return to play; clinical bio-mechanics; sports physiotherapy; wearable technology
(This special issue belongs to the Section Sports Medicine)
Multifactorial Causation and Therapies of Myopia: 2nd Edition submission deadline 26 Dec 2026 | 2 articles | Viewed by 2687 | Submission Open
Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
Harnessing the Power of Genomic Technologies for Personalized Medicine and Diagnosis
edited by and
submission deadline 27 Dec 2026 | Viewed by 171 | Submission Open
Keywords: personalized medicine; clinical genomics; next-generation sequencing (NGS); epigenomics; microbiome analysis; host–microbiome interactions
(This special issue belongs to the Section Clinical Laboratory Medicine)
From Biology to Bedside: Novel Clinical Strategies in Obesity-Linked Cardiometabolic Disease
edited by Matilda Florentin and
submission deadline 28 Dec 2026 | 2 articles | Viewed by 2085 | Submission Open
Keywords: obesity; cardiometabolic disease; type 2 diabetes; cardiovascular risk; adipose tissue dysfunction; inflammation; biomarkers; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Pediatric Ophthalmology: Current Progress and Future Options submission deadline 30 Dec 2026 | 5 articles | Viewed by 3460 | Submission Open
Keywords: pediatric ophthalmology; genetic eye diseases; gene therapy; genetic counseling; telemedicine; diagnostic tools; blindness in childhood; congenital cataract; visual rehabilitation; myopia control
(This special issue belongs to the Section Ophthalmology)
Advances in Trauma Surgery: Resuscitation, Critical Care, and Surgical Interventions submission deadline 30 Dec 2026 | 1 articles | Viewed by 831 | Submission Open
Keywords: trauma surgery; damage control resuscitation; whole blood; critical care; hemorrhage control; endovascular resuscitation; hybrid operating room; acute care surgery; soft tissue infections; vascular trauma; hepatobiliary trauma; trauma systems; global surgery; resuscitation strategies; surgical education
(This special issue belongs to the Section General Surgery)
Current Challenges in Syringomyelia
edited by
submission deadline 30 Dec 2026 | 1 articles | Viewed by 665 | Submission Open
Keywords: syringomyelia; epidemiology; genetics; hydrodynamics; cerebro-spinal fluid; MRI; neurophysiology; surgery; outcome measures; natural history
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates in Robotic and Robot-Assisted Surgery submission deadline 30 Dec 2026 | 1 articles | Viewed by 648 | Submission Open
Keywords: robot-assisted surgery; minimally invasive surgery; single-site surgery; surgical robotics; haptic feedback; artificial intelligence; robotic platforms; surgical precision; surgical outcomes; innovative surgical techniques; innovative robotic solutions
(This special issue belongs to the Section General Surgery)
Local Treatments for Oligometastatic Non-Small Cell Lung Cancer
edited by Elena Prisciandaro and
submission deadline 30 Dec 2026 | Viewed by 266 | Submission Open
Keywords: lung cancer; NSCLC; oligometastatic cancer; lung resection; lung surgery; pulmonary radiotherapy; SBRT; local treatments
(This special issue belongs to the Section Respiratory Medicine)
Advances in Musculoskeletal Tumor Surgery and Limb Salvage Reconstruction
edited by Alexander Christ and Brandon Gettleman
submission deadline 30 Dec 2026 | Viewed by 248 | Submission Open
Keywords: musculoskeletal oncology; limb salvage; sarcoma surgery; metastatic bone disease; oncologic reconstruction; patho-logic fracture; endoprosthetic reconstruction; arthroplasty; surgical outcomes; complications
(This special issue belongs to the Section Orthopedics)
Challenges in Gynecologic Cancers
edited by
submission deadline 30 Dec 2026 | Viewed by 234 | Submission Open
Keywords: ovarian cancer; endometrial cancer; uterine cancer; cervical cancer; vulvar cancer; nutrition in cancer; chemotherapy; immunotherapy; targeted therapies; surgery; mini-invasive surgery; robotic surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
New Advances in Wound Healing and Skin Wound Treatment
edited by Hajime Matsumura
submission deadline 31 Dec 2026 | 15 articles | Viewed by 39141 | Submission Open
Keywords: trauma wound; burns; chronic wound; DFU; VLU; ischemic wound; regenerative medicine in wound care; debridement; biofilm; wound dressing; antimicrobial treatment
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Sequelae of COVID-19: Clinical to Prognostic Follow-Up submission deadline 31 Dec 2026 | 15 articles | Viewed by 25246 | Submission Open
Keywords: COVID-19; post-COVID-19 syndromes; sequelae of COVID-19; pathophysiological pathways; multiorgan sequelae; long-term management of post-COVID-19 syndromes; quality of life; long-term prognosis of COVID-19
(This special issue belongs to the Section Vascular Medicine)
Clinical Research and Personalized Medicine in Inflammatory Bowel Disease
edited by and Loris Riccardo Lopetuso
submission deadline 31 Dec 2026 | 6 articles | Viewed by 10384 | Submission Open
Keywords: inflammatory bowel disease (IBD); personalized medicine; precision medicine; Crohn’s disease; ulcerative colitis; targeted therapy; artificial intelligence
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advancing Clinical Medicine Through Artificial Intelligence (AI) and Digital Technology: 2nd Edition submission deadline 31 Dec 2026 | 6 articles | Viewed by 9731 | Submission Open
Keywords: artificial intelligence; clinical medicine; medical imaging; precision medicine; clinical decision support systems; patient care; healthcare practices; early disease detection; patient outcomes
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Progress in Clinical Diagnosis and Therapy in Ophthalmology
edited by
submission deadline 31 Dec 2026 | 8 articles | Viewed by 7724 | Submission Open
Keywords: ophthalmic imaging; artificial intelligence in ophthalmology; retinal diseases; corneal transplantation; glaucoma diagnostics; ocular therapeutics; personalized medicine; ocular genetics
(This special issue belongs to the Section Ophthalmology)
Early Prevention and Diagnosis of Atherosclerosis: From Clinical Progression to Patient Management submission deadline 31 Dec 2026 | 3 articles | Viewed by 6425 | Submission Open
Keywords: atherosclerosis; atherothrombotic molecular pathways; cardiovascular risk; monitoring of goals; pharmacological and non-pharmacological prevention; carotid and peripheral interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy submission deadline 31 Dec 2026 | 3 articles | Viewed by 6104 | Submission Open
Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology
(This special issue belongs to the Section Pharmacology)
Clinical Advancements in Intraocular Lens Power Calculation Methods
edited by and Thomas Kohnen
submission deadline 31 Dec 2026 | 4 articles | Viewed by 5709 | Submission Open
Keywords: emmetropia; IOL power calculation; effective lens position; refractive lens exchange; IOL; refractive surgery; biometry
(This special issue belongs to the Section Ophthalmology)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 4 articles | Viewed by 5685 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition
edited by and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2904 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms
(This special issue belongs to the Section Cardiology)
Anemia: Clinical Updates in Diagnosis, Management, and Treatment submission deadline 31 Dec 2026 | 2 articles | Viewed by 2869 | Submission Open
Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia
(This special issue belongs to the Section Hematology)
Acute and Chronic Hemodialysis: Clinical Updates and Advances
edited by
submission deadline 31 Dec 2026 | 3 articles | Viewed by 2580 | Submission Open
Keywords: hemoadsorption; hemodiafiltration; medium cut-off membranes; expanded hemodialysis; vascular calcifications; renal anemia; vascular access; anticoagulation; ICU nephrology; acute kidney injury
(This special issue belongs to the Section Nephrology & Urology)
How Clinicians See the Use of AI in Psychiatry
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1507 | Submission Open
Keywords: artificial intelligence; psychiatry; patient care; psychotherapy
(This special issue belongs to the Section Mental Health)
Challenges and Solutions in Geriatric Fracture
edited by Detlef Van der Velde and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 1507 | Submission Open
Keywords: geriatric; fracture; frailty; hip fracture; comorbidity; perioperative optimization; orthogeriatrics; rehabilitation; shared decision-making; postoperative outcomes; mortality and morbidity; functional recovery; multidisciplinary care; quality of life; recovery; mobility; palliative care
(This special issue belongs to the Section Geriatric Medicine)
Advances in Artificial Intelligence Applications for Invasive and Non-Invasive Cardiovascular Procedures
edited by and Rahul Chaudhary
submission deadline 31 Dec 2026 | 2 articles | Viewed by 981 | Submission Open
Keywords: artificial intelligence and machine learning; interventional cardiology; electrophysiology; cardiovascular imaging; remote patient monitoring; digital biomarkers; clinical decision support
(This special issue belongs to the Section Cardiovascular Medicine)
Innovations in Heart Failure: Clinical and Surgical Perspectives
edited by and Vincenzo Tarzia
submission deadline 31 Dec 2026 | Viewed by 321 | Submission Open
Keywords: heart failure; heart transplantation; mechanical circulatory support; optimal medical therapy; LVAD; multidisciplinary care
(This special issue belongs to the Section Cardiology)
Critical Care Medicine: Innovation and Long-Term Patient Outcomes
edited by Charlie Corke
submission deadline 31 Dec 2026 | Viewed by 207 | Submission Open
Keywords: critical care innovation; patient-centred outcomes; goals-of-care decision-making; advanced organ sup-port; ethical and sustainable intensive care
(This special issue belongs to the Section Intensive Care)
Advances in Gynecological Cancers: Diagnosis, Treatment, and Care
edited by , Dariusz Wydra and
submission deadline 31 Dec 2026 | Viewed by 184 | Submission Open
Keywords: preinvasive cervical disease; cervical cancer; endometrial cancer; ovarian cancer; borderline ovarian tumors; rare tumors; uterine sarcoma; vulvar cancer; vaginal cancer; fertility sparing management; biomarkers; precision medicine; targeted therapy; immunotherapy; early detection
(This special issue belongs to the Section Obstetrics & Gynecology)
State of the Art of Corneal: Current Status and Prospects
edited by Justyna Izdebska
submission deadline 31 Dec 2026 | Viewed by 134 | Submission Open
Keywords: corneal diseases; corneal transplantation; OCT; corneal imaging; refractive surgery; keratoconus; graft survival; immunosuppression
(This special issue belongs to the Section Ophthalmology)
Multiparametric Ultrasound Techniques for Liver Disease Assessments
edited by Francesco Giangregorio
submission deadline 5 Jan 2027 | 2 articles | Viewed by 8139 | Submission Open
Keywords: ultrasound; multiparametric ultrasound; hepatic ultrasound; contrast-enhanced ultrasound; contrast agents; diffuse hepatic diseases; focal liver lesions; hepatic elastography; liver stiffness; hepatic endosonography; hepatic EUS
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Challenging ICU Dogma: Where Routine Practice and Evidence Collide
edited by and Nobutake Shimojo
submission deadline 10 Jan 2027 | 3 articles | Viewed by 14922 | Submission Open
Keywords: critical care; intensive care unit (ICU); clinical dogma; de-implementation; medical reversal; routine practices; clinical decision-making
(This special issue belongs to the Section Intensive Care)
New Clinical Advances in Pancreatobiliary Diseases
edited by
submission deadline 10 Jan 2027 | 4 articles | Viewed by 7790 | Submission Open
Keywords: pancreatobiliary diseases; EUS; ERCP; interventional endoscopy; targeted therapy; pancreatobiliary cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Thyroid Disorders: New Clinical Diagnosis and Management submission deadline 10 Jan 2027 | 2 articles | Viewed by 4175 | Submission Open
Keywords: thyroid disorders; clinical diagnosis; ultrasound; elastography; thyroid cancer; thyroiditis; hyperthyroidism; hypothyroidism; advanced imaging
(This special issue belongs to the Section Endocrinology & Metabolism)
Dialysis Versus Transplantation: Navigating Treatment Strategies in Chronic Kidney Disease
edited by
submission deadline 10 Jan 2027 | Viewed by 256 | Submission Open
Keywords: chronic kidney disease; kidney failure; dialysis; kidney transplantation; renal replacement therapy; hemodialysis; peritoneal dialysis; pre-emptive transplantation; patient-centered care; quality of life; precision nephrology; biomarkers; artificial intelligence; health disparities; treatment decision-making
(This special issue belongs to the Section Nephrology & Urology)
Clinical Management of Attention Deficit Hyperactivity Disorder (ADHD) submission deadline 15 Jan 2027 | 4 articles | Viewed by 12160 | Submission Open
Keywords: ADHD; addiction; neurodevelopmental disorders; levomethadone
(This special issue belongs to the Section Mental Health)
Updates on Treatment of Chronic Kidney Disease: Novel Approaches and Future Directions
edited by Pietro C. Dattolo and
submission deadline 15 Jan 2027 | 4 articles | Viewed by 7951 | Submission Open
Keywords: chronic kidney disease; CKD treatment; SGLT2 inhibitors; GLP-1 receptor agonists; non-steroidal MRAs; precision medicine; renal replacement therapy; novel therapeutics; clinical trials; nephrology
(This special issue belongs to the Section Nephrology & Urology)
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