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Advances in Trauma Surgery: Resuscitation, Critical Care, and Surgical Interventions

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 30 December 2026 | Viewed by 687

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Division of Trauma and Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD 21201, USA
Interests: trauma; acute care surgery; wounds; open abdomen
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Trauma remains one of the leading causes of death and disability worldwide, disproportionately affecting young and economically active populations. Over the past decades, significant advances in trauma care—including damage control resuscitation, hemostatic techniques, critical care optimization, and minimally invasive and endovascular interventions—have transformed outcomes in both civilian and military settings.

This Special Issue aims to highlight cutting-edge developments across the continuum of trauma care, from prehospital management to definitive surgical treatment and critical care. We invite original research and reviews, addressing topics such as whole blood resuscitation, viscoelastic testing, hybrid operating environments, advanced imaging, management of complex injuries (including vascular, hepatobiliary, and soft tissue infections), and innovations in trauma systems and education.

Particular emphasis will be placed on global trauma care disparities, and strategies to optimize outcomes in resource-limited settings. Contributions exploring multidisciplinary approaches and novel technologies are strongly encouraged.

This special issue aims to move the field of trauma surgery forward by gathering top-notch research that's based on facts and proven methods. It wants to shake up the current ways of thinking, encourage new ideas, and make a real difference in how trauma surgery is done all around the world.

Prof. Dr. Marcelo A. F. Ribeiro Jr.
Guest Editor

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • trauma surgery
  • damage control resuscitation
  • whole blood
  • critical care
  • hemorrhage control
  • endovascular resuscitation
  • hybrid operating room
  • acute care surgery
  • soft tissue infections
  • vascular trauma
  • hepatobiliary trauma
  • trauma systems
  • global surgery
  • resuscitation strategies
  • surgical education

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Published Papers (1 paper)

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14 pages, 2235 KB  
Systematic Review
Effectiveness of Platelet-Rich Plasma Combined with Split-Thickness Skin Grafts for Skin Defects: A Systematic Review and Meta-Analysis
by Rafael Dib Possiedi, Marcelo Augusto Fontenelle Ribeiro Junior, Lucas Fontenelle Vieira, Husna Irfan Thalib, Agata Grochowska-Krystman, Sariya Khan, Troy Shafer, Ayesha Jamal, Geovana Schulz and Jaques Waisberg
J. Clin. Med. 2026, 15(15), 6003; https://doi.org/10.3390/jcm15156003 - 2 Aug 2026
Viewed by 275
Abstract
Background/Objectives: Platelet-rich plasma (PRP) has been proposed as an adjunct to split-thickness skin grafting (STSG) to enhance graft adherence and reduce complications. However, evidence remains heterogeneous. This study evaluated the effectiveness of PRP combined with STSG compared with STSG alone. Methods: A systematic [...] Read more.
Background/Objectives: Platelet-rich plasma (PRP) has been proposed as an adjunct to split-thickness skin grafting (STSG) to enhance graft adherence and reduce complications. However, evidence remains heterogeneous. This study evaluated the effectiveness of PRP combined with STSG compared with STSG alone. Methods: A systematic review and meta-analysis was conducted following PRISMA guidelines. Databases and trial registries were searched for randomized controlled trials and comparative observational studies. Ten studies were included. The primary outcome was skin graft take. Secondary outcomes were wound healing time, graft loss, and hematoma incidence. Random-effects models were used. Risk of bias was assessed with RoB 2 and ROBINS-I, and certainty of evidence with GRADE. Results: Ten studies (7 randomized controlled trials and 3 observational studies) were included. PRP improved graft take (mean difference 9.93%; 95% CI: 4.70–15.17; p = 0.0002; I2 = 75%), with a larger effect in patient-level analyses (14.78; 95% CI: 10.97–18.59; p < 0.00001; I2 = 0%). Healing time could not be pooled. Hematoma incidence was reduced (risk ratio 0.26; 95% CI: 0.14–0.48; p < 0.0001; I2 = 0%). Graft loss was reduced in parallel-group trials (risk ratio 0.26; 95% CI: 0.11–0.58; p = 0.001; I2 = 0%) but not in sensitivity analysis (risk ratio 0.35; 95% CI: 0.10–1.19; p = 0.09; I2 = 73%). Evidence certainty was low to very low. Conclusions: PRP may improve graft take and reduce hematoma after STSG, but effects on graft loss and healing time remain uncertain. Full article
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