Sequelae of COVID-19: Clinical to Prognostic Follow-Up
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Vascular Medicine".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 697
Special Issue Editors
Interests: arterial hypertension; coronary artery disease; heart failure; pulmonary hypertension; cardiovascular alterations in patients with other pathologies
Special Issues, Collections and Topics in MDPI journals
2. Centre of Molecular Research in Nephrology and Vascular Disease, University of Medicine and Pharmacy “Vic-tor Babes” Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania
3. County Emergency Hospital “Pius Brinzeu”, L. Rebreanu, Nr. 156, 300723 Timisoara, Romania
Interests: pulmonary hypertension; heart failure; heart rate variability; myocarditis; pericarditis; COVID-19 and post-acute COVID-19 syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A year after the onset of the COVID-19 pandemic, when increasing numbers of patients were observed to have an unusually long and difficult recovery after an acute SARS-CoV-2 infection, researchers suspected that COVID-19 could have long-lasting sequelae. In 2020, post-acute COVID-19 syndrome was first mentioned in the medical literature, defined by the persistence of symptoms between 3 weeks and 3 months after an acute SARS-CoV-2 infection. Unfortunately, this was just the "tip of the iceberg", as several of these patients continued to present complaints or even new symptoms that occurred up to 6 months after contracting the SARS-CoV-2 infection. These subjects were diagnosed as having long COVID, which, according to the World Health Organization, has an incidence of 10–20% of all patients recovering from COVID-19. The symptoms cover a large spectrum since various systems and organs can be affected during the acute infection. The most frequently encountered sequelae are respiratory ones such as interstitial pulmonary fibrosis resulting in respiratory insufficiency, followed by multiple cardiovascular dysfunctions, with the most severe being pulmonary hypertension and chronic heart failure, not to forget neurological and psychiatric alterations, but also the renal, metabolic, hematological, or even gastrointestinal consequences of this disease. It should be mentioned that these sequelae rarely appear isolated; they are frequently associated and interrelated, severely affecting patients′ quality of life.
This Special Issue aims to focus on new insights concerning the underlying pathophysiological mechanisms, diagnosis, management, and complex treatment of COVID-19 sequelae. We welcome the submission of original articles, reviews, and clinical trials focused on new approaches to COVID-19 syndromes.
Dr. Mariana Tudoran
Dr. Cristina Tudoran
Guest Editors
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Keywords
- COVID-19
- post-COVID-19 syndromes
- sequelae of COVID-19
- pathophysiological pathways
- multiorgan sequelae
- long-term management of post-COVID-19 syndromes
- quality of life
- long-term prognosis of COVID-19
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