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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Advanced Imaging in Cardiology: Current Status and Future Directions

edited by

Moshe Rav-Acha

and

Arik Wolak

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1436 | Submission Open

Keywords: cardiac imaging; cardiac magnetic resonance; echocardiography; computed tomography; trans-thoracic echocardiography global longitudinal strain (GLS) analyses; radiomics

(This special issue belongs to the Section Cardiovascular Medicine)

Emerging Clinical Insights into Adolescent Behavioral Development and Mental Health

edited by

Ainzara Favini

and Anne-Marie Iselin

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1388 | Submission Open

Keywords: adolescence; behavioral development; clinical maladjustment; adolescents’ mental health; innovative clinical approach; adolescents’ emotional problems; clinical settings; innovative developmental research; adolescents’ symptoms

(This special issue belongs to the Section Mental Health)

Clinical Updates on Prenatal Diagnosis

edited by Valentina D'Ambrosio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1020 | Submission Open

Keywords: fetal anomalies; twin pregnancy; fetal therapy; prenatal genetic testing; genome sequencies

(This special issue belongs to the Section Obstetrics & Gynecology)

Perioperative Management in Thoracic Surgery: Current Advances and Future Perspectives

edited by

Roberto Cascone

and

Alfonso Fiorelli

submission deadline 31 Dec 2025 | 1 articles | Viewed by 854 | Submission Open

Keywords: thoracic surgery; perioperative care; ERAS; minimally invasive surgery; interventional pulmonology; preoperative assessment; postoperative management; surgical outcomes; multidisciplinary approach; technology in surgery

(This special issue belongs to the Section Respiratory Medicine)

Recent Progress and Future Directions in Orthopedic Oncology

edited by

Giuseppe Papalia

and Carmine Zoccali

submission deadline 31 Dec 2025 | 1 articles | Viewed by 851 | Submission Open

Keywords: orthopedic oncology; bone tumors; limb-sparing surgery; reconstruction techniques; 3D-printed implants; navigation and robotics; precision medicine in musculoskeletal oncology

(This special issue belongs to the Section Orthopedics)

Innovations in Psychosis and Schizophrenia: New Findings and Implications

edited by

Gabriele Nibbio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 703 | Submission Open

Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions

(This special issue belongs to the Section Mental Health)

Orthopedic Oncology Updates and Controversial Issues

edited by Yehuda Kollender and Ron Batash

submission deadline 31 Dec 2025 | Viewed by 316 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; oligometastatic; atypical behavior tumor; cryosurgery; rare diseases; surgery; radiation therapy; immunotherapy; chemotherapy

(This special issue belongs to the Section Orthopedics)

Clinical Challenges and Advances in Dry Eye Disease and Meibomian Gland Dysfunction

edited by

Salvatore Troisi

and

Livio Vitiello

submission deadline 31 Dec 2025 | Viewed by 276 | Submission Open

Keywords: dry eye disease; ocular surface; corneal disease; conjunctival disease; ocular biomarkers; patient-centered care; advanced diagnostics; regenerative medicine; artificial intelligence; therapeutic innovations

(This special issue belongs to the Section Ophthalmology)

Updates on Treatment of Chronic Kidney Disease: Novel Approaches and Future Directions

edited by Pietro C. Dattolo and

Aris Tsalouchos

submission deadline 31 Dec 2025 | Viewed by 215 | Submission Open

Keywords: chronic kidney disease; CKD treatment; SGLT2 inhibitors; GLP-1 receptor agonists; non-steroidal MRAs; precision medicine; renal replacement therapy; novel therapeutics; clinical trials; nephrology

(This special issue belongs to the Section Nephrology & Urology)

Advances in Gene Therapy for Retinal Diseases

edited by Tahreem Aman Mir

submission deadline 31 Dec 2025 | Viewed by 214 | Submission Open

Keywords: gene therapy; inherited retinal degenerations; age-related macular degeneration; diabetic retinopathy

(This special issue belongs to the Section Ophthalmology)

Clinical Trends in Diagnostic Radiology

edited by Wolfram Schwindt, Benjamin Noto and Anne Helfen

submission deadline 31 Dec 2025 | Viewed by 183 | Submission Open

Keywords: diagnostic imaging; radiology; nuclear medicine; hybrid imaging; artificial intelligence; radiomics; quantitative imaging; theranostics; imaging biomarkers; clinical applications

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Paradigms, Advances and Future Directions in Oral Medicine

edited by

Pia Lopez-Jornet

submission deadline 31 Dec 2025 | Viewed by 165 | Submission Open

Keywords: oral medicine; oral potentially malignant disorders; leukoplakia; oral lichen planus; orofacial pain; biopsy and liquid biopsy; biomarkers

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

The Atrial Fibrillation–Heart Failure Interconnection: Challenges and Innovations in Diagnosis and Treatment

edited by

Roberto De Ponti

and

Michele Golino

submission deadline 31 Dec 2025 | Viewed by 147 | Submission Open

Keywords: atrial fibrillation; catheter ablation; ventricular dysfunction; myocardial remodeling; diastolic dysfunction; biomarkers; anti-arrhythmia agents; risk assessment; artificial intelligence; telemedicine

(This special issue belongs to the Section Cardiovascular Medicine)

Progress in the Multimodal Treatment of Pancreatic Disease

edited by

Gennaro Nappo

submission deadline 31 Dec 2025 | Viewed by 142 | Submission Open

Keywords: pancreatic diseases; pancreatic cancer; multimodal treatment; neoadjuvant therapy; imaging techniques; minimally invasive surgery; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Optimizing Outcomes in Deep Vein Thrombosis: A Focus on Interventional Management

edited by Adam Gwozdz

submission deadline 31 Dec 2025 | Viewed by 112 | Submission Open

Keywords: deep vein thrombosis; post-thrombotic syndrome; venous patency; emerging technology; vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment

edited by

Camilla Gesi

submission deadline 5 Jan 2026 | 1 articles | Viewed by 2425 | Submission Open

Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted

(This special issue belongs to the Section Mental Health)

Advances in Diagnosis and Management of Pancreatobiliary Disorders—2nd Edition

edited by

Francesca Lodato

submission deadline 9 Jan 2026 | 3 articles | Viewed by 2762 | Submission Open

Keywords: pancreas diseases; pancreatic tumors; biliary tract diseases and neoplams; ERCP; EUS; cholangioscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Clinical Advances in Pancreatobiliary Diseases

edited by

Kyong Joo Lee

submission deadline 9 Jan 2026 | 1 articles | Viewed by 702 | Submission Open

Keywords: pancreatobiliary diseases; EUS; ERCP; interventional endoscopy; targeted therapy; pancreatobiliary cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Advance in Chronic Total Occlusion Percutaneous Coronary Intervention

edited by Anbukarasi Maran and Kevin Croce

submission deadline 9 Jan 2026 | Viewed by 122 | Submission Open

Keywords: chronic total occlusion (CTO); percutaneous coronary intervention (PCI); innovative techniques; guidewire technology; retrograde PCI; interventional cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Heart Disease and Chronic Inflammatory Conditions: New Insights

edited by Ofer Kobo and Gilad Margolis

submission deadline 10 Jan 2026 | 4 articles | Viewed by 11887 | Submission Open

Keywords: heart diseases; chronic inflammatory; rheumatoid arthritis; cardiovascular disease; inflammatory bowel disease

(This special issue belongs to the Section Cardiology)

Clinical Guidelines in Critical Care Medicine

edited by

Ana Vujaklija Brajković

Andrej Markota

and Daniela Bandic-Pavlovic

submission deadline 10 Jan 2026 | 3 articles | Viewed by 5721 | Submission Open

Keywords: critical illness; immunocompromised host; biomarkers; thrombocytopenia; blood coagulation disorders; multiple trauma; diagnostic imaging

(This special issue belongs to the Section Intensive Care)

Heart Failure and Coronary Artery Diseases: Cardiovascular Complications and Comorbidities

edited by

Dhrubajyoti Bandyopadhyay

Vikash Jaiswal

and

Adrija Hajra

submission deadline 10 Jan 2026 | 2 articles | Viewed by 3495 | Submission Open

Keywords: heart failure; acute myocardial infarction; coronary artery diseases; cardiac imaging; biomarkers; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Advancements in Spinal Oncology: The Current Landscape

edited by Aladine Elsamadicy and

Daniel M. Sciubba

submission deadline 10 Jan 2026 | 1 articles | Viewed by 1749 | Submission Open

Keywords: spinal oncology; patient outcomes; primary bone tumor; spine metastases; intradural tumors

(This special issue belongs to the Section Clinical Neurology)

From Acute Injury to Personalized Prevention—Developing Modern Strategies

edited by

Markus Gesslein

and

Eduard Kurz

submission deadline 10 Jan 2026 | 2 articles | Viewed by 1665 | Submission Open

Keywords: orthopedics; acute injury; personalized prevention; innovative methodologies; musculoskeletal disorders; musculoskeletal injury; conservative therapy; functional testing; intervention

(This special issue belongs to the Section Orthopedics)

Advanced Physiotherapy Practice in Patients with Musculoskeletal Disorders

edited by

Filippo Maselli

and

Firas Mourad

submission deadline 10 Jan 2026 | Viewed by 151 | Submission Open

Keywords: differential diagnosis; physiotherapy; rehabilitation; multidisciplinary; effectiveness; musculoskeletal disorders; screening for referral; manual therapy; exercise; cognitive behavioral therapy; pain neuroscience

(This special issue belongs to the Section Clinical Rehabilitation)

Pelvic Organ Prolapse: Clinical Advances and Challenges

edited by

Barbara Bodner-Adler

submission deadline 10 Jan 2026 | Viewed by 148 | Submission Open

Keywords: pelvic organ prolapse; pessary treatment; uterus-preserving prolapse surgery; clinical management; clinical treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Vascular and Endovascular Surgery: Second Edition

edited by

Fadi Taher

and Afshin Assadian

submission deadline 11 Jan 2026 | 4 articles | Viewed by 2942 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic surgery; peripheral arterial disease; vascular imaging; EVAR; FEVAR; vascular access; vascular education; aneurysms

(This special issue belongs to the Section Vascular Medicine)

Clinical Updates in Physiotherapy for Musculoskeletal Disorders

edited by

Santiago Navarro Ledesma

submission deadline 15 Jan 2026 | 10 articles | Viewed by 23184 | Submission Open

Keywords: musculoskeletal disorders; physiotherapy interventions; lifestyle; psychoneuroimmunology; chronic pain; inflammation; physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Physical Therapy in Neurorehabilitation

edited by

Marianna Papadopoulou

and

George K. Papadimas

submission deadline 15 Jan 2026 | 8 articles | Viewed by 19673 | Submission Open

Keywords: physical therapy; transcutaneous electrical nerve stimulation (TENS); muscle strengthening; balance exercising; pain; quality of life; neurodegenerative disorders; neuromuscular disorders; stroke; demyelinating disorders

(This special issue belongs to the Section Clinical Neurology)

Innovative Systemic Treatments for Atopic Dermatitis

edited by

Luigi Gargiulo

submission deadline 15 Jan 2026 | 5 articles | Viewed by 14322 | Submission Open

Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib

(This special issue belongs to the Section Dermatology)

Clinical Application of Biomarkers in Cancers

edited by

Monica Florescu

submission deadline 15 Jan 2026 | 3 articles | Viewed by 12805 | Submission Open

Keywords: cancer biomarkers; early detection; personalized therapy; biomarker validation; advanced technologies; clinical implementation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Current Trends and Prospects of Critical Emergency Medicine

edited by Quincy K. Tran

submission deadline 15 Jan 2026 | 8 articles | Viewed by 7299 | Submission Open

Keywords: critically ill patients; critical care; resuscitation; emergency medicine; trends; prospects; outcomes

(This special issue belongs to the Section Emergency Medicine)

Advances in Pulmonary Disease Management and Innovation in Treatment

edited by

Monica Steluța Marc

and

Florin Mihaltan

submission deadline 15 Jan 2026 | 4 articles | Viewed by 5525 | Submission Open

Keywords: severe asthma; COPD; sleep-related breathing disorders; respiratory tract infections; innovative respiratory therapies; translational pulmonary research; pulmonary vascular disease; interstitial lung disease; eHealth in respiratory care

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 15 Jan 2026 | 3 articles | Viewed by 4463 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Pulmonary Embolism—Current and Novel Approaches

edited by Roy Beigel and Shlomi Matetzky

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3969 | Submission Open

Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification

(This special issue belongs to the Section Respiratory Medicine)

Safety in Spinal Surgery

edited by Simon B. Roberts and

Thanos Tsirikos

submission deadline 15 Jan 2026 | 1 articles | Viewed by 3567 | Submission Open

Keywords: spinal surgery; patients with spinal deformity; inherent risks; risk management; surgery safety

(This special issue belongs to the Section General Surgery)

Clinical Advances in Minimally Invasive Urologic Surgery

edited by

Umberto Carbonara

, Fabio Crocerossa and

Savio Domenico Pandolfo

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3560 | Submission Open

Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 15 Jan 2026 | 2 articles | Viewed by 3075 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Clinical Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

edited by Fabrizio Guarracini and

Marisa Varrenti

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2403 | Submission Open

Keywords: cardiac arrhythmias; antiarrhythmic agents; pacemakers; cardiac resynchronization; catheter ablation; electrophysiology

(This special issue belongs to the Section Cardiology)

Up-to-Date Research in Liver Transplantation

edited by

Pierluigi Toniutto

submission deadline 15 Jan 2026 | 1 articles | Viewed by 2213 | Submission Open

Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA); perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Management of Aortic Diseases: Drafting from Theoretical Aspects to Clinical Practice—2nd Edition

edited by

Mario D’Oria

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1792 | Submission Open

Keywords: aortic disease; aortic aneurysm; aortic dissection; aortic surgery; diagnosis and management

(This special issue belongs to the Section Cardiovascular Medicine)

Pediatric Nephrology: Advances in the Diagnosis and Management of Pediatric Kidney Disorders

edited by

Agnieszka Rybi-Szumińska

and

Anna Maria Wasilewska

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1438 | Submission Open

Keywords: diagnosis; management; treatment; kidney disorders; chronic kidney disease; biomarkers; genetic testing; kidney; children; newborn

(This special issue belongs to the Section Nephrology & Urology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Jan 2026 | 1 articles | Viewed by 1183 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Intracranial Hemorrhage: Advances in Diagnosis, Management and Treatment

edited by Hitoshi Fukuda

submission deadline 15 Jan 2026 | 1 articles | Viewed by 852 | Submission Open

Keywords: intracerebral hemorrhage; subarachnoid hemorrhage; traumatic hemorrhage; prehospital care; less invasive surgery; vascular malformation; antihypertensive drug; intracranial pressure elevation; decompressive craniectomy; neurocritical care; nursing care; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Pediatric Urology: How to Adapt Current Knowledge to the New Era

edited by Simona Gerocarni Nappo and

Elisa Cerchia

submission deadline 15 Jan 2026 | Viewed by 413 | Submission Open

Keywords: pediatric urology; telemedicine; telesurgery; artificial intelligence; 3D-models; congenital urinary diseases; pediatric oncology

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Oculoplastic Surgery and Ocular Surface Diseases

edited by Michael T. Yen, Francesco Quaranta Leoni and

Balestrazzi Alessandra

submission deadline 15 Jan 2026 | Viewed by 185 | Submission Open

Keywords: ocular surface disease; corneal neurotization; neurotrophic keratopathy; eyelid malposition; facial nerve palsy; thyroid eye disease; oculoplastic surgery; hemocomponents; dry anophthalmic socket; corneal pathology; ocular surface reconstruction; exposure keratopathy

(This special issue belongs to the Section Ophthalmology)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 15 Jan 2026 | Viewed by 153 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations

edited by

Akshay Kumar

and

Mohamed Rahouma

submission deadline 15 Jan 2026 | Viewed by 145 | Submission Open

Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology

(This special issue belongs to the Section Cardiovascular Medicine)

Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management

edited by Gil Nissim Bachar and Ram Dickman

submission deadline 15 Jan 2026 | Viewed by 132 | Submission Open

Keywords: acute pancreatitis; pancreatic inflammation; necrotizing pancreatitis; clinical outcomes; ultrasound examination

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Pulmonary Critical Care: Diagnosis and Treatment of Respiratory System Diseases

edited by Yaron Bar-Lavie

submission deadline 15 Jan 2026 | Viewed by 131 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); mechanical ventilation; chronic obstructive pulmonary disease (COPD); sepsis-induced lung injury; pulmonary fibrosis; bronchoscopy in critical care

(This special issue belongs to the Section Intensive Care)

Displaying special issue 401-450 on page 9 of 31.

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