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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ischemic and Hemorrhagic Complications of Uncommon Cerebrovascular Diseases: Cutting-Edge Clinical Research, Reviews, and Expert Opinions

edited by Mariel G. Kozberg and Alexis T. Roy

submission deadline 24 Oct 2025 | Viewed by 101 | Submission Open

Keywords: cerebrovascular disease; ischemic stroke; hemorrhagic stroke; genetics; vasculopathy; headache; superficial siderosis; vascular malformations

(This special issue belongs to the Section Clinical Neurology)

Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives

edited by

Valeria Visco

Michele Ciccarelli

and

Costantino Mancusi

submission deadline 25 Oct 2025 | 9 articles | Viewed by 10263 | Submission Open

Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease

(This special issue belongs to the Section Cardiovascular Medicine)

Hereditary Hemorrhagic Telangiectasia: Recent Advances and Future Challenges—2nd Edition

edited by

Carmelo Bernabeu

Marco Post

and

Hans-Jurgen Mager

submission deadline 25 Oct 2025 | 8 articles | Viewed by 7981 | Submission Open

Keywords: hereditary hemorrhagic telangiectasia (HHT); ALK1; ACVRL1; endoglin (ENG); arteriovenous malformations; embolization; VEGF

(This special issue belongs to the Section Vascular Medicine)

Colon and Rectal Surgery: Current Clinical Practice and Future Trends

edited by Konstantinos Romanidis

submission deadline 25 Oct 2025 | 6 articles | Viewed by 7331 | Submission Open

Keywords: colorectal surgery; colorectal cancer; complications; metastasis; artificial intelligence; cancer metabolism

(This special issue belongs to the Section General Surgery)

Digital Health Technologies in Parkinson’s Disease and Related Disorders

edited by Ruth B. Schneider and Christine Doss Esper

submission deadline 25 Oct 2025 | 6 articles | Viewed by 6235 | Submission Open

Keywords: digital health technologies; telehealth; wearables; smartphones; Parkinson’ s disease; atypical parkinsonism

(This special issue belongs to the Section Clinical Neurology)

Clinical Perspectives on Surgical Management of Knee Injuries

edited by Min Jung

submission deadline 25 Oct 2025 | 4 articles | Viewed by 4899 | Submission Open

Keywords: osteoarthritis; meniscal repair; ligament reconstruction; cartilage restoration; knee surgery

(This special issue belongs to the Section Orthopedics)

Current Status, Challenges and Future Directions in Aortic Valve Replacement

edited by Guglielmo Saitto and Giovanni Alfonso Chiariello

submission deadline 25 Oct 2025 | 5 articles | Viewed by 4274 | Submission Open

Keywords: aortic valve; aortic valve replacement; minimally invasive surgery; robotic surgery; TAVI; ross operation; root enlargement techniques; heart team; lifetime management

(This special issue belongs to the Section Cardiology)

Assessment and Treatment of Trauma Patients

edited by

Arne Driessen

submission deadline 25 Oct 2025 | 2 articles | Viewed by 2909 | Submission Open

Keywords: trauma surgery; prehospital detection of trauma; assessment of trauma; trauma scale; trauma evaluation; trauma surgery

(This special issue belongs to the Section Emergency Medicine)

Paediatric Anaesthesia: Clinical Updates and Perspectives

edited by Peter Marhofer, Philipp Opfermann and Markus Zadrazil

submission deadline 25 Oct 2025 | 4 articles | Viewed by 2840 | Submission Open

Keywords: pediatric anesthesia; anesthesia; conduction; ultrasonography; conscious sedation; deep sedation; drug-related side effects and adverse reactions; neurotoxicity syndromes

(This special issue belongs to the Section Anesthesiology)

Migraine Headache: Symptoms, Diagnosis, and Current Treatment

edited by Ināra Logina

submission deadline 25 Oct 2025 | 3 articles | Viewed by 2554 | Submission Open

Keywords: migraine; headache disorders; burden of headache disorders; acute and preventive treatment of migraine; neuropathic pain

(This special issue belongs to the Section Clinical Neurology)

Current Treatment and Future Options of Ischemic Stroke

edited by Raluca Elena Sandu and Carmen Valeria Albu

submission deadline 25 Oct 2025 | 1 articles | Viewed by 2532 | Submission Open

Keywords: ischemic stroke; stroke; neuroinflammation; cerebral ischemia; thrombolysis; neuroprotection; rehabilitation strate-gies; stroke biomarkers; extracellular vesicles; stem cell therapy; post-stroke recovery; cerebral ischemia; advanced imaging in stroke; personalized stroke treatment

(This special issue belongs to the Section Clinical Neurology)

Management in Autism Spectrum Disorder: From Biomarkers to Precision Medicine

edited by

Michele Roccella

and

Alessandra Carta

submission deadline 25 Oct 2025 | 2 articles | Viewed by 2312 | Submission Open

Keywords: autism; autism spectrum disorder; neurodevelopmental disorders; epigenetics of autism; genetic inheritance; immunogenetics

(This special issue belongs to the Section Mental Health)

Clinical Management of Temporomandibular Joint Diseases

edited by

Nansi López-Valverde

and

Bruno Macedo Sousa

submission deadline 25 Oct 2025 | 3 articles | Viewed by 2255 | Submission Open

Keywords: temporomandibular joint disorders; dental occlusion; chronic pain; occlusal splints; risk factors

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Optimizing Outcomes in Scoliosis and Complex Spinal Surgery

edited by Francis C. Lovecchio

submission deadline 25 Oct 2025 | 2 articles | Viewed by 1829 | Submission Open

Keywords: outcomes; complications; scoliosis; adult spinal deformity; proximal junctional kyphosis; complex spine; pseudarthrosis

(This special issue belongs to the Section Orthopedics)

Targeted Medicine in Postoperative Pain Management

edited by

Martina Rekatsina

and Eleni Moka

submission deadline 25 Oct 2025 | 2 articles | Viewed by 1561 | Submission Open

Keywords: precision medicine; postoperative analgesia; pain control; drug delivery systems; surgical pain management; personalized interventions

(This special issue belongs to the Section Anesthesiology)

Autoimmune Skin Diseases: Innovations, Challenges, and Opportunities

edited by Shany Sherman

submission deadline 25 Oct 2025 | 2 articles | Viewed by 1532 | Submission Open

Keywords: healthcare utilization; inflammatory skin diseases; photodermatoses; collagen vascular disease; immunobullous disorders; graft-versus-host disease

(This special issue belongs to the Section Dermatology)

Advancements in Diagnostic Innovations in Sports Cardiology

edited by Giuseppe Di Gioia, Maria Rosaria Squeo and

Stefano Palermi

submission deadline 25 Oct 2025 | 1 articles | Viewed by 1203 | Submission Open

Keywords: athletes; cardiovascular prevention; risk factors; sport cardiology; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Advances in Clinical Anesthesia and Analgesia: Novel Approaches for Optimal Patient Safety and Comfort

edited by Cesare Gregoretti and Giuliano Lo Bianco

submission deadline 25 Oct 2025 | 2 articles | Viewed by 1159 | Submission Open

Keywords: pain management; pain medicine; anesthesia; analgesia; anesthesiology

(This special issue belongs to the Section Anesthesiology)

Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases

edited by

Calin Pop

and

Antoniu Petris

submission deadline 25 Oct 2025 | 1 articles | Viewed by 812 | Submission Open

Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease

(This special issue belongs to the Section Cardiology)

Clinical Trends and Prospects in Laboratory Hematology

edited by

Olga Ciepiela

submission deadline 25 Oct 2025 | 1 articles | Viewed by 773 | Submission Open

Keywords: laboratory hematology; hemostasis; flow cytometry; molecular diagnostics; blood cells; complete blood count

(This special issue belongs to the Section Clinical Laboratory Medicine)

Cardiac Magnetic Resonance Imaging: Current Techniques and Future Directions

edited by Ioannis Botis and

Theodoros D. Karamitsos

submission deadline 25 Oct 2025 | 1 articles | Viewed by 772 | Submission Open

Keywords: cardiac magnetic resonance imaging; cardiovascular magnetic resonance; cardiac imaging; multimodality imaging; parametric mapping; late gadolinium enhancement; myocardial perfusion; myocardial viability; cardiomyopathies; heart failure

(This special issue belongs to the Section Cardiology)

Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases

edited by Madalina Ilie and Mihai Ciocîrlan

submission deadline 25 Oct 2025 | 1 articles | Viewed by 570 | Submission Open

Keywords: esogastric lesions; pancreatic diseases; colorectal lesions; hepatobiliary diseases; optical endoscopy; endoscopic ultrasound; upper and lower endoscopy; endoscopic retrograde cholangiopancreatography

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Hand Surgery: Latest Advances and Prospects

edited by

Camillo Fulchignoni

and Lorenzo Rocchi

submission deadline 25 Oct 2025 | 1 articles | Viewed by 476 | Submission Open

Keywords: hand surgery; musculoskeletal and nerve disorders; innovative surgical procedures; minimally invasive techniques; rehabilitation strategies; robotic surgery

(This special issue belongs to the Section Orthopedics)

Oral and Maxillofacial Surgery: Current Advances and Future Directions

edited by Niedzielska Iwona

submission deadline 25 Oct 2025 | 1 articles | Viewed by 449 | Submission Open

Keywords: oral and maxillofacial surgery; reconstructive surgery; periodontitis; dental implants; maxillofacial deformities

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Imaging and Interventional Techniques for Renal and Adrenal Diseases

edited by Francesco Ziglioli and Umberto Vittorio Maestroni

submission deadline 25 Oct 2025 | 1 articles | Viewed by 341 | Submission Open

Keywords: renal cancer; adrenal mass; robotic surgery; minimally invasive techniques; radiomics; tailored treatment

(This special issue belongs to the Section Nephrology & Urology)

Robot-Assisted Surgery: Current Trends and Future Directions

edited by

Michele Di Dio

, Claudio Bisegna and Michele Morelli

submission deadline 25 Oct 2025 | Viewed by 279 | Submission Open

Keywords: robotic surgery; minimally invasive surgery; urology; artificial intelligence; augmented reality; public health; innovation; laparoscopic surgery; surgical platforms; surgical outcomes

(This special issue belongs to the Section General Surgery)

Interventional Cardiology: Recent Advances and Future Perspectives

edited by Cristina Aurigemma and Luigi Cappannoli

submission deadline 25 Oct 2025 | Viewed by 202 | Submission Open

Keywords: interventional cardiology; percutaneous coronary intervention (PCI); transcatheter aortic valve implantation (TAVI); structural heart disease; coronary artery disease; imaging and artificial intelligence; antithrombotic therapy; future technologies in cardiology; personalized cardiovascular care; minimally invasive interventions

(This special issue belongs to the Section Cardiology)

Testicular Cancer: Clinical Advances in Diagnosis and Treatment

edited by

Markus Lerchbaumer

, Andreas Maxeiner and

Thomas Fischer

submission deadline 25 Oct 2025 | Viewed by 178 | Submission Open

Keywords: testicular cancer; ultrasound imaging; computed tomography; new imaging modalities; personalized medicine; oncology; surgical treatment

(This special issue belongs to the Section Oncology)

Clinical Management of Frailty

edited by

Alejandro Alvarez-Bustos

, Walter Sepulveda-Loyola and

Isabel Rodríguez-Sánchez

submission deadline 25 Oct 2025 | Viewed by 139 | Submission Open

Keywords: frailty; comprehensive geriatric assessment; assessment; monitoring; functional decline; physical performance; ex-ercise interventions; nutritional strategies; interventions; adverse outcomes

(This special issue belongs to the Section Geriatric Medicine)

New Clinical Insights into Cardiac Pacing and Cardiac Resynchronization Therapy

edited by Massimo Zecchin

submission deadline 25 Oct 2025 | Viewed by 132 | Submission Open

Keywords: cardiac pacing; cardiac resynchronization therapy (CRT); cardiac conduction system pacing; left bundle branch area pacing; leadless pacing; short- and long-term outcomes; implantation technique

(This special issue belongs to the Section Cardiology)

Respiratory Medicine in the Oldest-Old

edited by

Takae Ebihara

submission deadline 25 Oct 2025 | Viewed by 125 | Submission Open

Keywords: oldest-old; respiratory system with aging; pneumonia; epidemiology; COPD; interstitial lung disease; bronchial asthma; lung cancer; mycobacterial or fungal infections; peri-/post-operative status; respiratory frailty; social problems and end of life

(This special issue belongs to the Section Respiratory Medicine)

Oral Cancer: Clinical Updates and Perspectives

edited by

Jutta Ries

Mayte Buchbender

and

Ulrike Simone Speth

submission deadline 25 Oct 2025 | Viewed by 122 | Submission Open

Keywords: oral cancer; oral surgery; dental implant; tooth extraction; oral health; early detection; biomarkers; targeted therapy; immunotherapy

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances and Clinical Outcomes of Endocrinology

edited by Stefana Catalina Bilha and

Cristina Preda

submission deadline 25 Oct 2025 | Viewed by 117 | Submission Open

Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions

(This special issue belongs to the Section Endocrinology & Metabolism)

Management and Prognosis of Spinal Surgery

edited by Francesco Costa

submission deadline 25 Oct 2025 | Viewed by 116 | Submission Open

Keywords: spine; spinal surgery; spinal biomechanics; microneurosurgery; vertebral oncology

(This special issue belongs to the Section Clinical Neurology)

Advances in Primary Sclerosing Cholangitis: Pathogenesis, Diagnosis and Emerging Therapies

edited by Konstantinos H. Katsanos and Fotios S. Fousekis

submission deadline 25 Oct 2025 | Viewed by 116 | Submission Open

Keywords: cholangiocarcinoma; primary sclerosing cholangitis; cholestatic; inflammatory bowel disease; liver

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Global Expert Views on Aortic Valve Repair and Replacement: 2nd Edition

edited by

Jose Alberto De Agustín

submission deadline 25 Oct 2025 | Viewed by 111 | Submission Open

Keywords: aortic valve pathologies; minimally invasive approach; aortic valve repair; aortic valve replacement; imaging techniques

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Gastrointestinal Endoscopy

edited by

Ivan Žaja

and Željko Puljiz

submission deadline 25 Oct 2025 | Viewed by 102 | Submission Open

Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Novel Insights into Colorectal Surgery

edited by

Valentin Calu

submission deadline 25 Oct 2025 | Viewed by 100 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Pathophysiology of Hypertension and Related Diseases: 2nd Edition

edited by

Tomislav Bulum

and

Ingrid Prkačin

submission deadline 25 Oct 2025 | Viewed by 97 | Submission Open

Keywords: arterial hypertension; resistant hypertension; secondary hypertension; prevention and screening of hypertension; hypertensive crisis; treatment of hypertension; obstructive sleep apnea syndrome; pathophysiology of hypertension; hypertension and the environment; (pre)hypertension and genetics

(This special issue belongs to the Section Vascular Medicine)

New Concepts in Minimally Invasive Spine Surgery

edited by

Yi Lu

and Michael Y. Wang

submission deadline 25 Oct 2025 | Viewed by 95 | Submission Open

Keywords: minimally invasive spine surgery; image navigation; tubular retractor; endoscopic spine surgery; virtual and aug-mented reality; lateral spine surgery

(This special issue belongs to the Section Clinical Neurology)

Recent Advances in the Diagnosis and Treatment of Gastrointestinal Diseases

edited by

Ahamed Khalyfa

submission deadline 27 Oct 2025 | 3 articles | Viewed by 2522 | Submission Open

Keywords: advanced endoscopy; innovation in GI; pathophysiology of GI disorders; artificial intelligence in GI; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Chronic Kidney Disease: Global Dimension and Perspectives

edited by Valentina Câmpean

submission deadline 28 Oct 2025 | 1 articles | Viewed by 1095 | Submission Open

Keywords: histological changes; renal dysfunction; kidney diseases; glomerulonephritis; polycystic kidney disease; kidney failure; kidney cancer; atherosclerosis; heart disease; renal and renovascular hypertension

(This special issue belongs to the Section Nephrology & Urology)

Prostate Surgery: The Latest Advances and Future Trends

edited by Akhil K. Das and

Bruce Gao

submission deadline 28 Oct 2025 | Viewed by 151 | Submission Open

Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP; ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation

(This special issue belongs to the Section Nephrology & Urology)

Symptoms and Treatment of Cardiac Amyloidosis

edited by Syed Bukhari

submission deadline 28 Oct 2025 | Viewed by 135 | Submission Open

Keywords: cardiac amyloidosis; transthyretin amyloidosis; light chain amyloidosis; cardiac magnetic resonance; echocardiography; nuclear scintigraphy; endomyocardial biopsy; gene silencers; transthyretin stabilizers; immunotherapy

(This special issue belongs to the Section Cardiology)

Recent Advances and Clinical Outcomes of Hip and Knee Arthroplasty

edited by

Andrea Volpin

submission deadline 28 Oct 2025 | Viewed by 99 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; clinical outcomes; surgical innovation; patient recovery; prosthetics; perioperative care

(This special issue belongs to the Section Orthopedics)

Diagnosis, Treatment, and Management of Gastrointestinal Oncology

edited by Toufic A. Kachaamy and Madappa N. Kundranda

submission deadline 30 Oct 2025 | 3 articles | Viewed by 9058 | Submission Open

Keywords: gastrointestinal oncology; endoscopic oncology; biliary tract cancer; colorectal cancer; esophageal cancer; stomach cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Biomarkers and Lung Cancer: Clinical Application

edited by

Roberto Gasparri

submission deadline 30 Oct 2025 | 5 articles | Viewed by 5901 | Submission Open

Keywords: lung cancer; early diagnosis; prognosis; biomarkers; body fluids; liquid biopsy

(This special issue belongs to the Section Respiratory Medicine)

New Update on Personalized Treatment of Autism Spectrum Disorder and Related Disorders

edited by

Francesca Cucinotta

, Rosamaria Siracusano and Erica Pironti

submission deadline 30 Oct 2025 | 2 articles | Viewed by 4940 | Submission Open

Keywords: autism spectrum disorder; autism related disorders; children and adolescents; intervention strategies; therapeutic advance; new technologies; evidence-based practices

(This special issue belongs to the Section Mental Health)

Advances in Anesthesia for Cardiac Surgery

edited by Christopher M. Munch and

Pietro Giorgio Malvindi

submission deadline 30 Oct 2025 | 5 articles | Viewed by 4855 | Submission Open

Keywords: enhanced recovery after cardiac surgery (ERACS); minimally invasive cardiac surgery (MICS); ultra-fast-track an-esthesia; chest wall blocks in cardiac anesthesia; opioid-free anesthesia in cardiac surgery; neurologic dysfunction and cardiac surgery; pre- and posthabilitation in cardiac surgery

(This special issue belongs to the Section Anesthesiology)

Clinical Highlights in Chronic Obstructive Pulmonary Disease (COPD)

edited by

Richard Zuwallack

and Dimosthenis Lykouras

submission deadline 30 Oct 2025 | 4 articles | Viewed by 4140 | Submission Open

Keywords: COPD treatment; inhalers; patient-reported outcomes; COPD rehabilitation; cardiovascular risk

(This special issue belongs to the Section Respiratory Medicine)

Displaying special issue 601-650 on page 13 of 28.

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